aminoglutethimide has been researched along with Hypothyroidism in 6 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clinical and biochemical evidence of hypothyroidism (thyrotropin levels greater than 10 mU/L) was noted in nine of 29 patients treated following the initiation of aminoglutethimide (250 mg four times daily)." | 7.69 | Hypothyroidism associated with aminoglutethimide in patients with prostate cancer. ( Calis, KA; Cooper, MR; Figg, WD; Headlee, D; Mays, D; Sartor, AO; Thibault, A, 1994) |
| "Clinical and biochemical evidence of hypothyroidism (thyrotropin levels greater than 10 mU/L) was noted in nine of 29 patients treated following the initiation of aminoglutethimide (250 mg four times daily)." | 3.69 | Hypothyroidism associated with aminoglutethimide in patients with prostate cancer. ( Calis, KA; Cooper, MR; Figg, WD; Headlee, D; Mays, D; Sartor, AO; Thibault, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cury, Y | 1 |
| Garcia-Leme, J | 1 |
| Figg, WD | 1 |
| Thibault, A | 1 |
| Sartor, AO | 1 |
| Mays, D | 1 |
| Headlee, D | 1 |
| Calis, KA | 1 |
| Cooper, MR | 1 |
| McLaren, EH | 1 |
| Alexander, WD | 1 |
| Rallison, ML | 1 |
| Kumagai, LF | 1 |
| Tyler, FH | 1 |
| Hughss, SW | 1 |
| Burley, DM | 1 |
| Philbert, M | 1 |
| Luton, JP | 1 |
| Mathieu de Fossey, B | 1 |
| Bricaire, H | 1 |
2 reviews available for aminoglutethimide and Hypothyroidism
| Article | Year |
|---|---|
Goitrogens.
Topics: Adult; Aminoglutethimide; Animals; Antithyroid Agents; Carbimazole; Cobalt; Ethionamide; Female; Fet | 1979 |
Aminoglutethimide: a "side-effect" turned to therapeutic advantage.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocortical Hyperfunctio | 1970 |
4 other studies available for aminoglutethimide and Hypothyroidism
| Article | Year |
|---|---|
The inflammatory response of hyperthyroid and hypothyroid rats. Role of adrenocortical steroids.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Aminoglutethimide; Animals; Ascorbic Acid; Histamine; Hyper | 1984 |
Hypothyroidism associated with aminoglutethimide in patients with prostate cancer.
Topics: Aged; Aminoglutethimide; Diagnosis, Differential; Humans; Hypothyroidism; Male; Prospective Studies; | 1994 |
Goitrous hypothyroidism induced by amino-glutethimide, anticonvulsant drug.
Topics: Adolescent; Aminoglutethimide; Animals; Anticonvulsants; Child; Child, Preschool; Chromatography; Fe | 1967 |
[Corticosteroidogenesis inhibitors. II. A new cortico-adrenal inhibitor: amino-glutethimide (16,038Ba)].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal G | 1968 |