Page last updated: 2024-11-02

aminosalicylic acid and Hypothyroidism

aminosalicylic acid has been researched along with Hypothyroidism in 12 studies

Aminosalicylic Acid: An antitubercular agent often administered in association with ISONIAZID. The sodium salt of the drug is better tolerated than the free acid.
4-aminosalicylic acid : An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism were reported."7.71[Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism]. ( Horiba, M; Kimura, T; Mizutani, H; Shindoh, J; Son, M; Wakahara, K, 2001)
" Hypothyroidism is a common AE associated with ethionamide, p-aminosalicylic acid (PAS), and stavudine."3.79High rate of hypothyroidism in multidrug-resistant tuberculosis patients co-infected with HIV in Mumbai, India. ( Andries, A; Dalal, A; Das, M; Desai, C; Fernandes, D; Isaakidis, P; Khan, S; Mansoor, H; Migliori, GB; Paryani, R; Saranchuk, P; Sotgiu, G; Verma, R, 2013)
" Clinical data, serum thyroid stimulating hormone (TSH) and free thyroxine (fT4) levels were retrospectively assessed in 137 children receiving anti-tuberculosis treatment including ETH."3.77Abnormal thyroid function tests in children on ethionamide treatment. ( Hesseling, AC; Magdorf, K; Schaaf, HS; Thee, S; Willemse, M; Zöllner, EW, 2011)
"Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism were reported."3.71[Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism]. ( Horiba, M; Kimura, T; Mizutani, H; Shindoh, J; Son, M; Wakahara, K, 2001)
"Ethionamide and PAS were the most frequently reported drugs that associated with the occurrence of hypothyroidism."2.61Is hypothyroidism rare in multidrug resistance tuberculosis patients on treatment? A systematic review and meta-analysis. ( Holakouie-Naieni, K; Lejisa, T; Mansournia, MA; Mola, M; Tesfaye, E; Tola, HH; Yaseri, M, 2019)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tola, HH1
Holakouie-Naieni, K1
Lejisa, T1
Mansournia, MA1
Yaseri, M1
Tesfaye, E1
Mola, M1
Andries, A1
Isaakidis, P1
Das, M1
Khan, S1
Paryani, R1
Desai, C1
Dalal, A1
Mansoor, H1
Verma, R1
Fernandes, D1
Sotgiu, G1
Migliori, GB1
Saranchuk, P1
Thee, S1
Zöllner, EW1
Willemse, M1
Hesseling, AC1
Magdorf, K1
Schaaf, HS1
BERGQVIST, N1
DE MARE, O1
RISKA, N2
DAVIES, HT1
GALBRAITH, HJ1
BUTTARO, CA1
MACGREGOR, AG1
SOMNER, AR1
STRUTINSKII, MI1
Soumakis, SA1
Berg, D1
Harris, HW1
Mizutani, H1
Horiba, M1
Shindoh, J1
Kimura, T1
Son, M1
Wakahara, K1

Reviews

1 review available for aminosalicylic acid and Hypothyroidism

ArticleYear
Is hypothyroidism rare in multidrug resistance tuberculosis patients on treatment? A systematic review and meta-analysis.
    PloS one, 2019, Volume: 14, Issue:6

    Topics: Aminosalicylic Acid; Antitubercular Agents; Cross-Sectional Studies; Drug-Related Side Effects and A

2019

Other Studies

11 other studies available for aminosalicylic acid and Hypothyroidism

ArticleYear
High rate of hypothyroidism in multidrug-resistant tuberculosis patients co-infected with HIV in Mumbai, India.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adult; Aminosalicylic Acid; Cohort Studies; Coinfection; Ethionamide; Female; HIV Infections; Humans

2013
Abnormal thyroid function tests in children on ethionamide treatment.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2011, Volume: 15, Issue:9

    Topics: Adolescent; Aminosalicylic Acid; Antitubercular Agents; Child; Child, Preschool; Ethionamide; Euthyr

2011
Hypothyroidism and cerebral edema following combined treatment of tuberculosis with conteben (TB I 698) and p-amino-salicylic acid.
    Acta medica Scandinavica, 1952, Aug-05, Volume: 143, Issue:5

    Topics: Aminosalicylic Acid; Brain Edema; Combined Modality Therapy; Hypothyroidism; Thioacetazone; Thiosemi

1952
[Thyroid dysfunction and PAS].
    Nordisk medicin, 1952, Sep-19, Volume: 48, Issue:38

    Topics: Aminosalicylic Acid; Hyperthyroidism; Hypothyroidism; Tuberculosis; Tuberculosis, Pulmonary

1952
Goitre and hypothyroidism developing during treatment with P.A.S.
    British medical journal, 1953, Jun-06, Volume: 1, Issue:4822

    Topics: Aminosalicylic Acid; Goiter; Hypothyroidism

1953
[Effects of PAS on thyroid function].
    Nordisk medicin, 1953, Feb-20, Volume: 49, Issue:8

    Topics: Aminosalicylic Acid; Hyperthyroidism; Hypothyroidism

1953
[Antithyroid action of paraaminosalicylic acid and isonicotinic acid hydrazide].
    La Riforma medica, 1953, Mar-28, Volume: 67, Issue:13

    Topics: Aminosalicylic Acid; Hyperthyroidism; Hypothyroidism; Isoniazid; Niacin; Nicotinic Acids; Thyroid Gl

1953
The anti-thyroid action of para-aminosalicylic acid.
    Lancet (London, England), 1954, Nov-06, Volume: 267, Issue:6845

    Topics: Aminosalicylic Acid; Goiter; Humans; Hypothyroidism; Tuberculosis

1954
[THYROID FUNCTION IN PATIENTS WITH PULMONARY TUBERCULOSIS AND ITS MODIFICATION DURING THE COURSE OF ANTIBACTERIAL THERAPY].
    Problemy tuberkuleza, 1964, Volume: 42

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Drug Therapy; Hyperthyroidism; Hyp

1964
Hypothyroidism in a patient receiving treatment for multidrug-resistant tuberculosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:4

    Topics: Aminosalicylic Acid; Antitubercular Agents; Humans; Hypothyroidism; Male; Middle Aged; Tuberculosis,

1998
[Two cases of multi-drug-resistant pulmonary tuberculosis with para-aminosalicylic acid (PAS)-induced hypothyroidism].
    Kekkaku : [Tuberculosis], 2001, Volume: 76, Issue:10

    Topics: Adult; Aged; Aminosalicylic Acid; Antitubercular Agents; Drug Therapy, Combination; Female; Humans;

2001