dantrolene has been researched along with Hypothyroidism in 3 studies
Dantrolene: Skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. It is used in spasticity and other neuromuscular abnormalities. Although the mechanism of action is probably not central, dantrolene is usually grouped with the central muscle relaxants.
dantrolene : The hydrazone resulting from the formal condensation of 5-(4-nitrophenyl)furfural with 1-aminohydantoin. A ryanodine receptor antagonist used for the relief of chronic severe spasticity and malignant hyperthermia.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1 The effects of dantrolene on twitch and tetanic force development were determined in soleus and gastrocnemius muscle of euthyroid, hypothyroid, and hyperthyroid rats." | 7.67 | Effects of dantrolene on force development in slow- and fast-twitch muscle of euthyroid, hypothyroid, and hyperthyroid rats. ( Everts, ME; van Hardeveld, C, 1987) |
| "1 The effects of dantrolene on twitch and tetanic force development were determined in soleus and gastrocnemius muscle of euthyroid, hypothyroid, and hyperthyroid rats." | 3.67 | Effects of dantrolene on force development in slow- and fast-twitch muscle of euthyroid, hypothyroid, and hyperthyroid rats. ( Everts, ME; van Hardeveld, C, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Hardeveld, C | 2 |
| Kassenaar, AA | 1 |
| Everts, ME | 2 |
| Clausen, T | 1 |
3 other studies available for dantrolene and Hypothyroidism
| Article | Year |
|---|---|
A possible role for Ca2+ in thyroid hormone-dependent oxygen consumption in skeletal muscle of the rat.
Topics: Animals; Calcium; Dantrolene; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Male; Muscles; O | 1980 |
Effects of dantrolene on force development in slow- and fast-twitch muscle of euthyroid, hypothyroid, and hyperthyroid rats.
Topics: Animals; Dantrolene; Electric Stimulation; Hyperthyroidism; Hypothyroidism; Male; Muscle Contraction | 1987 |
Effects of thyroid hormones on calcium contents and 45Ca exchange in rat skeletal muscle.
Topics: Animals; Calcium; Calcium Radioisotopes; Dantrolene; Female; Gallopamil; Hyperthyroidism; Hypothyroi | 1986 |