gamma-aminobutyric acid has been researched along with Hypothyroidism in 20 studies
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " He had been administered phenytoin and gabapentin for the treatment of symptomatic traumatic epilepsy 8 years before." | 7.88 | Hypothyroidism induced by phenytoin and gabapentin: A Case Report. ( Ishii, K; Miyake, Z; Tamaoka, A, 2018) |
| "The aspartic acid, glutamic acid, and gamma-aminobutyric acid (GABA) contents were determined in four central auditory system regions in rats with transient neonatal hypothyroidism compared with control ones: the ventral and dorsal parts of the cochlear nucleus, the central nucleus of the inferior colliculus, the auditory cortex, and in an extra-auditory structure, the substantia nigra pars reticulata." | 7.67 | Effect of transient neonatal hypothyroidism on the free aspartic acid, glutamic acid, and GABA content of different central auditory regions in the rat. ( Barden, N; Dussault, JH; Hébert, R; Poulin, R, 1987) |
| " He had been administered phenytoin and gabapentin for the treatment of symptomatic traumatic epilepsy 8 years before." | 3.88 | Hypothyroidism induced by phenytoin and gabapentin: A Case Report. ( Ishii, K; Miyake, Z; Tamaoka, A, 2018) |
| " In our article, we report two sisters, one of whom was treated with levothyroxine because of hypothyroidism." | 3.80 | Transient hypothyroidism induced by anticonvulsant agents. ( Krysiak, R; Stojko, R, 2014) |
| "The effects of adult-onset hypothyroidism on the metabolic compartmentation of the cerebral tricarboxylic acid cycle and the gamma-aminobutyric acid (GABA) shunt have been investigated by 13C nuclear magnetic resonance spectroscopy." | 3.69 | Adult-onset hypothyroidism and the cerebral metabolism of (1,2-13C2) acetate as detected by 13C nuclear magnetic resonance. ( Calvo, R; Cerdán, S; Chapa, F; Escobar del Rey, F; Künnecke, B; Morreale de Escobar, G, 1995) |
| "The aspartic acid, glutamic acid, and gamma-aminobutyric acid (GABA) contents were determined in four central auditory system regions in rats with transient neonatal hypothyroidism compared with control ones: the ventral and dorsal parts of the cochlear nucleus, the central nucleus of the inferior colliculus, the auditory cortex, and in an extra-auditory structure, the substantia nigra pars reticulata." | 3.67 | Effect of transient neonatal hypothyroidism on the free aspartic acid, glutamic acid, and GABA content of different central auditory regions in the rat. ( Barden, N; Dussault, JH; Hébert, R; Poulin, R, 1987) |
| "The effect of di-n-propylacetic acid (valproic acid), an inhibitor of gamma aminobutyric acid (GABA) transaminase, was studied with reference to its effect on the serum concentration of thyroid hormones, baseline serum TSH concentration and TRH stimulated TSH release, in seven normal controls and six patients with primary hypothyroidism." | 3.66 | Effect of di-N-propylacetic acid (valproic acid) on the TSH response to TRH--a presumptive role for gamma aminobutyric acid. ( Elias, AN; Grossman, M; Szekeres, AV; Valenta, LJ, 1981) |
| "Compounds to treat hypothyroidism in the absence of cardiac side effects are urgently required." | 1.51 | Analysis of the protective effects of γ-aminobutyric acid during fluoride-induced hypothyroidism in male Kunming mice. ( Li, P; Liu, S; Xing, R; Yang, H; Yu, H, 2019) |
| "Fifteen patients with primary hypothyroidism and 15 matched healthy controls underwent single-voxel MEGA-PRESS magnetic resonance spectroscopy at 3T, to quantify GABA levels in the median prefrontal cortex (mPFC) and posterior cingulate cortex (PCC)." | 1.46 | Investigation of brain GABA+ in primary hypothyroidism using edited proton MR spectroscopy. ( Chen, W; Edden, RA; Gao, F; Gong, T; Liu, B; Wang, G; Wang, Q; Wang, Z; Yang, H; Zhao, B, 2017) |
| "Hypothyroidism affects neurogenesis." | 1.38 | Similar distribution changes of GABAergic interneuron subpopulations in contrast to the different impact on neurogenesis between developmental and adult-stage hypothyroidism in the hippocampal dentate gyrus in rats. ( Akane, H; Mitsumori, K; Morita, R; Ohishi, T; Shibutani, M; Shiraki, A; Suzuki, K; Wang, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 9 (45.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, B | 2 |
| Wang, Z | 2 |
| Lin, L | 1 |
| Yang, H | 4 |
| Gao, F | 2 |
| Gong, T | 2 |
| Edden, RAE | 1 |
| Wang, G | 2 |
| Miyake, Z | 1 |
| Ishii, K | 1 |
| Tamaoka, A | 1 |
| Xing, R | 2 |
| Liu, S | 2 |
| Yu, H | 2 |
| Li, P | 2 |
| Sawano, E | 1 |
| Takahashi, M | 1 |
| Negishi, T | 1 |
| Tashiro, T | 1 |
| Krysiak, R | 1 |
| Stojko, R | 1 |
| Abd Allah, ES | 1 |
| Gomaa, AM | 1 |
| Sayed, MM | 1 |
| Wang, Q | 1 |
| Zhao, B | 1 |
| Chen, W | 1 |
| Edden, RA | 1 |
| Friauf, E | 1 |
| Wenz, M | 1 |
| Oberhofer, M | 1 |
| Nothwang, HG | 1 |
| Balakrishnan, V | 1 |
| Knipper, M | 1 |
| Löhrke, S | 1 |
| Hadjab-Lallemend, S | 1 |
| Wallis, K | 1 |
| van Hogerlinden, M | 1 |
| Dudazy, S | 1 |
| Nordström, K | 1 |
| Vennström, B | 1 |
| Fisahn, A | 1 |
| Shiraki, A | 1 |
| Akane, H | 1 |
| Ohishi, T | 1 |
| Wang, L | 1 |
| Morita, R | 1 |
| Suzuki, K | 1 |
| Mitsumori, K | 1 |
| Shibutani, M | 1 |
| Arvio, M | 1 |
| Sipilä, I | 1 |
| Cuevas, E | 1 |
| Ausó, E | 1 |
| Telefont, M | 1 |
| Morreale de Escobar, G | 2 |
| Sotelo, C | 1 |
| Berbel, P | 2 |
| Manzano, J | 1 |
| Cuadrado, M | 1 |
| Morte, B | 1 |
| Bernal, J | 1 |
| Elias, AN | 1 |
| Valenta, LJ | 1 |
| Szekeres, AV | 1 |
| Grossman, M | 1 |
| Chapa, F | 1 |
| Künnecke, B | 1 |
| Calvo, R | 1 |
| Escobar del Rey, F | 1 |
| Cerdán, S | 1 |
| Marco, P | 1 |
| Cerezo, JR | 1 |
| DeFelipe, J | 1 |
| Kalaria, RN | 1 |
| Prince, AK | 1 |
| Hébert, R | 1 |
| Poulin, R | 1 |
| Barden, N | 1 |
| Dussault, JH | 1 |
| Sánchez-Herranz, A | 1 |
| Martín del Rio, R | 1 |
| Montoya, E | 1 |
20 other studies available for gamma-aminobutyric acid and Hypothyroidism
| Article | Year |
|---|---|
Brain GABA+ changes in primary hypothyroidism patients before and after levothyroxine treatment: A longitudinal magnetic resonance spectroscopy study.
Topics: Brain; gamma-Aminobutyric Acid; Humans; Hypothyroidism; Magnetic Resonance Spectroscopy; Thyroxine | 2020 |
Hypothyroidism induced by phenytoin and gabapentin: A Case Report.
Topics: Aged; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Epilepsy; Gabapentin; gamma-Aminobutyric | 2018 |
Analysis of the protective effects of γ-aminobutyric acid during fluoride-induced hypothyroidism in male Kunming mice.
Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric | 2019 |
Thyroid hormone-dependent development of the GABAergic pre- and post-synaptic components in the rat hippocampus.
Topics: Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Gen | 2013 |
Transient hypothyroidism induced by anticonvulsant agents.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamm | 2014 |
The effect of omega-3 on cognition in hypothyroid adult male rats.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Calcium Channels, L-Type; Carbimazole; Cognition; Co | 2014 |
γ-Aminobutyric acid ameliorates fluoride-induced hypothyroidism in male Kunming mice.
Topics: Animals; Apoptosis; Epithelial Cells; Fluorides; GABA Agents; gamma-Aminobutyric Acid; Hypothyroidis | 2016 |
Investigation of brain GABA+ in primary hypothyroidism using edited proton MR spectroscopy.
Topics: Adult; Brain; Brain Chemistry; Case-Control Studies; Female; gamma-Aminobutyric Acid; Gyrus Cinguli; | 2017 |
Hypothyroidism impairs chloride homeostasis and onset of inhibitory neurotransmission in developing auditory brainstem and hippocampal neurons.
Topics: Animals; Antithyroid Agents; Auditory Pathways; Brain Stem; Chlorides; Female; gamma-Aminobutyric Ac | 2008 |
A mutant thyroid hormone receptor alpha1 alters hippocampal circuitry and reduces seizure susceptibility in mice.
Topics: Animals; Brain; Calbindin 2; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Hypo | 2010 |
Similar distribution changes of GABAergic interneuron subpopulations in contrast to the different impact on neurogenesis between developmental and adult-stage hypothyroidism in the hippocampal dentate gyrus in rats.
Topics: Age Factors; Animals; Antithyroid Agents; Apoptosis; Cell Proliferation; Dentate Gyrus; Dose-Respons | 2012 |
[Psychomotor slowness of a mentally retarded woman].
Topics: Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexan | 2001 |
Transient maternal hypothyroxinemia at onset of corticogenesis alters tangential migration of medial ganglionic eminence-derived neurons.
Topics: Animals; Brain Mapping; Calbindins; Cell Count; Cell Movement; Cells, Cultured; Cerebral Cortex; Emb | 2005 |
Influence of thyroid hormone and thyroid hormone receptors in the generation of cerebellar gamma-aminobutyric acid-ergic interneurons from precursor cells.
Topics: Acetates; Age Factors; Animals; Blotting, Western; Cell Differentiation; Cell Proliferation; Cerebel | 2007 |
Effect of di-N-propylacetic acid (valproic acid) on the TSH response to TRH--a presumptive role for gamma aminobutyric acid.
Topics: 4-Aminobutyrate Transaminase; Adult; Female; gamma-Aminobutyric Acid; Humans; Hypothyroidism; Male; | 1981 |
Adult-onset hypothyroidism and the cerebral metabolism of (1,2-13C2) acetate as detected by 13C nuclear magnetic resonance.
Topics: Acetates; Age of Onset; Animals; Brain; Brain Chemistry; Carbon Isotopes; Electronic Data Processing | 1995 |
Distribution of parvalbumin immunoreactivity in the neocortex of hypothyroid adult rats.
Topics: Animals; Cerebral Cortex; gamma-Aminobutyric Acid; Hypothyroidism; Image Processing, Computer-Assist | 1996 |
Decreased neurotransmitter receptor binding in striatum and cortex from adult hypothyroid rats.
Topics: Animals; Choline O-Acetyltransferase; Corpus Striatum; Dioxanes; gamma-Aminobutyric Acid; Glutamate | 1986 |
Effect of transient neonatal hypothyroidism on the free aspartic acid, glutamic acid, and GABA content of different central auditory regions in the rat.
Topics: Animals; Animals, Newborn; Aspartic Acid; Auditory Cortex; Cochlea; gamma-Aminobutyric Acid; Glutama | 1987 |
In vivo effects of gamma-aminobutyric acid and beta-alanine on thyrotrophin secretion in the normal and hypothyroid rat.
Topics: Alanine; Animals; beta-Alanine; Brain; gamma-Aminobutyric Acid; Hypothyroidism; Male; Rats; Secretor | 1985 |