Page last updated: 2024-11-07

carbachol and Hypothyroidism

carbachol has been researched along with Hypothyroidism in 12 studies

Carbachol: A slowly hydrolyzed CHOLINERGIC AGONIST that acts at both MUSCARINIC RECEPTORS and NICOTINIC RECEPTORS.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"The effects of hypothyroidism on the muscarinic cholinergic receptor-coupled inositol phospholipid hydrolysis in the adult rat brain were examined."7.68Hypothyroidism inhibits the formation of inositol phosphate in response to carbachol in the striatum of adult rat. ( Iriuchijima, T; Michimata, T; Mizuma, H; Mori, M; Murakami, M; Yamada, M, 1991)
" As the mechanism of this effect has not been fully known, in this experimental study the isolated gastric acid secretion of hypothyroid and hyperthyroid rats were compared with control group by the administration of different doses of pentagastrin, histamine and carbachol as gastric acid secretion stimulators."3.72Effects of thyroid hormones on basal and stimulated gastric acid secretion due to histamine, carbachol and pentagastrin in rats. ( Naseri, MK; Rafsanjani, FN; Vahedian, J; Z Asl, S, 2003)
"The effects of hypothyroidism on the muscarinic cholinergic receptor-coupled inositol phospholipid hydrolysis in the adult rat brain were examined."3.68Hypothyroidism inhibits the formation of inositol phosphate in response to carbachol in the striatum of adult rat. ( Iriuchijima, T; Michimata, T; Mizuma, H; Mori, M; Murakami, M; Yamada, M, 1991)
"Hypothyroidism has been reported to occur in 6% of impotent men."1.33Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits. ( Bagcivan, I; Kaya, K; Kilicarslan, H; Sarac, B; Yildirim, MK; Yildirim, S, 2006)
"Hypothyroidism has been reported to occur in 6% of impotent men."1.33Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits. ( Bagcivan, I; Kaya, T; Kilicarslan, H; Sarac, B; Yildirim, MK, 2006)
" The dose producing a 35% decrease in sGaw (PD35) was determined from the cumulative log dose-response curve by linear regression analysis."1.28Effects of hypothyroidism on bronchial reactivity in non-asthmatic subjects. ( Hombach, V; Keck, FS; Schäuffelen, AC; Seibold, H; von Beauvais, H; Wieshammer, S, 1990)
"Hyperthyroidism was induced by daily injections of L-triiodothyronine and hypothyroidism by a single injection of 131I."1.26Insulin secretory response to different secretagogues in hyper- and hypothyroid mice. ( Ahrén, B; Lundquist, I, 1981)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's4 (33.33)18.2507
2000's3 (25.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bagheripuor, F1
Ghanbari, M1
Piryaei, A1
Ghasemi, A1
Rafsanjani, FN1
Z Asl, S1
Naseri, MK1
Vahedian, J1
Sarac, B2
Yildirim, MK2
Bagcivan, I2
Kaya, K1
Kilicarslan, H2
Yildirim, S1
Kaya, T1
Ahrén, B1
Lundquist, I1
Simpson, WW2
Rodgers, RL1
McNeill, JH2
Kragie, L1
Kwon, YW1
Smiehorowski, R1
Pintor, A1
Fortuna, S1
Lorenzini, P1
Pascale, A1
Battaini, F1
Avellino, C1
Malvezzi Campeggi, L1
Salvati, S1
Iriuchijima, T2
Michimata, T2
Mizuma, H1
Murakami, M1
Yamada, M1
Mori, M2
Wieshammer, S1
Keck, FS1
Schäuffelen, AC1
von Beauvais, H1
Seibold, H1
Hombach, V1
Akuzawa, M1
Yamaguchi, M1
Kobayashi, S1

Other Studies

12 other studies available for carbachol and Hypothyroidism

ArticleYear
Effects of fetal hypothyroidism on uterine smooth muscle contraction and structure of offspring rats.
    Experimental physiology, 2018, 05-01, Volume: 103, Issue:5

    Topics: Animals; Carbachol; Female; Fetus; Hypothyroidism; Muscle Contraction; Muscle, Smooth; Oxytocin; Pre

2018
Effects of thyroid hormones on basal and stimulated gastric acid secretion due to histamine, carbachol and pentagastrin in rats.
    Saudi medical journal, 2003, Volume: 24, Issue:4

    Topics: Animals; Carbachol; Female; Gastric Acid; Histamine; Hyperthyroidism; Hypothyroidism; Male; Pentagas

2003
Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits.
    International journal of urology : official journal of the Japanese Urological Association, 2006, Volume: 13, Issue:1

    Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electric Stimulation; Hypothyroidi

2006
Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits.
    The journal of sexual medicine, 2006, Volume: 3, Issue:5

    Topics: Animals; Carbachol; Cyclic GMP; Disease Models, Animal; Electric Stimulation; Hypothyroidism; Impote

2006
Insulin secretory response to different secretagogues in hyper- and hypothyroid mice.
    Acta endocrinologica, 1981, Volume: 97, Issue:4

    Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cholecystokinin; Female; Glucose; Hyperthyroidism; Hyp

1981
Cardiac responsiveness to alpha and beta adrenergic amines: effects of carbachol and hypothyroidism.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbachol; Heart; Hypothyroidism; In V

1981
The effect of carbachol and isoproterenol on the responses of the atria to methoxamine in euthyroid and hypothyroid rats.
    Proceedings of the Western Pharmacology Society, 1980, Volume: 23

    Topics: Animals; Carbachol; Heart; Heart Rate; Hypothyroidism; In Vitro Techniques; Isoproterenol; Methoxami

1980
Rat cardiac calcium channels and their relationships with beta-adrenergic and muscarinic receptors in hypothyroidism.
    Endocrine research, 1993, Volume: 19, Issue:1

    Topics: Animals; Calcium; Calcium Channels; Carbachol; Dose-Response Relationship, Drug; Heart Rate; Hypothy

1993
Influences of hypothyroidism on lipid composition and inositol lipid-linked receptors responsiveness and protein kinase C (PKC) activity in the cerebral cortex of Lewis rats.
    Neurochemical research, 1996, Volume: 21, Issue:5

    Topics: Animals; Carbachol; Cerebral Cortex; Cycloleucine; Hypothyroidism; Inositol; Inositol Phosphates; Ma

1996
Hypothyroidism inhibits the formation of inositol phosphate in response to carbachol in the striatum of adult rat.
    Research communications in chemical pathology and pharmacology, 1991, Volume: 73, Issue:2

    Topics: Animals; Atropine; Binding Sites; Carbachol; Cell Membrane; Cerebral Cortex; Corpus Striatum; Hippoc

1991
Effects of hypothyroidism on bronchial reactivity in non-asthmatic subjects.
    Thorax, 1990, Volume: 45, Issue:12

    Topics: Acute Disease; Adult; Airway Resistance; Bronchial Diseases; Bronchial Provocation Tests; Carbachol;

1990
Hypothyroidism enhances carbachol-induced hypothermia in the rat.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 65, Issue:1

    Topics: Animals; Atropine; Body Temperature; Carbachol; Hypothyroidism; Male; Rats; Rats, Inbred Strains; Th

1989