dehydroepiandrosterone has been researched along with Hypothyroidism in 22 studies
Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Objective The present study was aimed at assessing whether oral dehydroepiandrosterone affects thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in men with subclinical hypothyroidism induced by Hashimoto's thyroiditis." | 8.02 | Impact of dehydroepiandrosterone on thyroid autoimmunity and function in men with autoimmune hypothyroidism. ( Krysiak, R; Okopień, B; Szkróbka, W, 2021) |
| " We examined serum concentrations of ADIOL, ADIOLS, DHEA, DHEAS and pregnenolone sulfate (5-pregnen-3beta-ol-20-one sulfate, PREGS) in patients with Graves' thyrotoxicosis (male/female 9/14), hypothyroidism (11/20) and in normal controls (14/29)." | 7.71 | Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism. ( Amino, N; Fukata, S; Izumi, Y; Kobayashi, Y; Kuma, K; Tada, H; Tagawa, N; Takano, T, 2001) |
| "We were interested if the treatment of hypothyroidism would affect the above factors." | 5.31 | Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine. ( Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A, 2001) |
| " Objective The present study was aimed at assessing whether oral dehydroepiandrosterone affects thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in men with subclinical hypothyroidism induced by Hashimoto's thyroiditis." | 4.02 | Impact of dehydroepiandrosterone on thyroid autoimmunity and function in men with autoimmune hypothyroidism. ( Krysiak, R; Okopień, B; Szkróbka, W, 2021) |
| " We examined serum concentrations of ADIOL, ADIOLS, DHEA, DHEAS and pregnenolone sulfate (5-pregnen-3beta-ol-20-one sulfate, PREGS) in patients with Graves' thyrotoxicosis (male/female 9/14), hypothyroidism (11/20) and in normal controls (14/29)." | 3.71 | Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism. ( Amino, N; Fukata, S; Izumi, Y; Kobayashi, Y; Kuma, K; Tada, H; Tagawa, N; Takano, T, 2001) |
| "Plasma dehydroepiandrosterone sulphate (DHEAS), cortisol (F) and prolactin (PRL) were measured in seventeen premenopausal women with primary hypothyroidism and in fifteen normal premenopausal women." | 3.66 | Plasma dehydroepiandrosterone sulphate in hypothyroid premenopausal women. ( Bassi, F; Fiorelli, G; Forti, G; Giannotti, P; Pinchera, A; Pupi, A; Serio, M, 1980) |
| " New preparations are being developed to better mimic normal physiological cortisol levels with convenient, once-daily dosing which may improve treatment outcomes." | 2.49 | Therapy of endocrine disease: Perspectives on the management of adrenal insufficiency: clinical insights from across Europe. ( Grossman, A; Johannsson, G; Quinkler, M; Zelissen, P, 2013) |
| "Hypothyroidism was significantly more common in patients after chemoradiotherapy than in those who received only chemotherapy (χ2=9." | 1.91 | [Endocrine disorders after combined chemoradiotherapy in Hodgkin Lymphoma survivors]. ( Fazullina, ON; Klimontov, VV; Pospelova, TI; Shebunyaeva, YY; Voytko, MS, 2023) |
| "Future studies on primary hypothyroidism should focus on role of lower DHEAS levels in inducing symptoms of fatigue and joint pains." | 1.62 | Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism. ( Agarwal, M; Ganeshani, M; Jangir, R; Kandel, G; Sankanagoudar, S; Shukla, R; Srivastava, S, 2021) |
| "We were interested if the treatment of hypothyroidism would affect the above factors." | 1.31 | Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine. ( Bicíková, M; Hill, M; Putz, Z; Tallová, J; Tomandl, J; Vañuga, A, 2001) |
| "Dehydroepiandrosterone (DHEA) is a peroxisome proliferating agent when administered in pharmacological dosages, but it has not been shown to function through the peroxisome proliferator-activated receptor in cell-based assays." | 1.29 | Regulation of CYP4A expression in rat by dehydroepiandrosterone and thyroid hormone. ( Geoghegan, TE; Prough, RA; Webb, SJ; Xiao, GH, 1996) |
| "Hypothyroidism is associated with a severe retardation of body growth, which appears more marked in thyroidectomized than in MMI treated rats; no significant variations in testis weight are observed." | 1.28 | Influence of hypothyroidism on in-vitro testicular steroidogenesis in adult rats. ( Andó, S; Beraldi, E; Fugassa, E; Palmero, S; Panno, ML; Prati, M; Salerno, M; Tarantino, G, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 4 (18.18) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Voytko, MS | 1 |
| Klimontov, VV | 1 |
| Pospelova, TI | 1 |
| Shebunyaeva, YY | 1 |
| Fazullina, ON | 1 |
| Krysiak, R | 1 |
| Szkróbka, W | 1 |
| Okopień, B | 1 |
| Shukla, R | 1 |
| Ganeshani, M | 1 |
| Agarwal, M | 1 |
| Jangir, R | 1 |
| Kandel, G | 1 |
| Sankanagoudar, S | 1 |
| Srivastava, S | 1 |
| Aicher, KM | 1 |
| Cullen, JM | 1 |
| Seiler, GS | 1 |
| Lunn, KF | 1 |
| Mathews, KG | 1 |
| Gookin, JL | 1 |
| Grossman, A | 1 |
| Johannsson, G | 1 |
| Quinkler, M | 1 |
| Zelissen, P | 1 |
| Diamanti-Kandarakis, E | 1 |
| Dattilo, M | 1 |
| Macut, D | 1 |
| Duntas, L | 1 |
| Gonos, ES | 1 |
| Goulis, DG | 1 |
| Gantenbein, CK | 1 |
| Kapetanou, M | 1 |
| Koukkou, E | 1 |
| Lambrinoudaki, I | 1 |
| Michalaki, M | 1 |
| Eftekhari-Nader, S | 1 |
| Pasquali, R | 1 |
| Peppa, M | 1 |
| Tzanela, M | 1 |
| Vassilatou, E | 1 |
| Vryonidou, A | 1 |
| Maggi, M | 1 |
| Buvat, J | 1 |
| Corona, G | 1 |
| Guay, A | 1 |
| Torres, LO | 1 |
| Drbalová, K | 1 |
| Matucha, P | 1 |
| Matějková-Běhanová, M | 1 |
| Bílek, R | 1 |
| Kříž, L | 1 |
| Kazihnitková, H | 1 |
| Hampl, R | 1 |
| Földes, J | 2 |
| Fehér, T | 2 |
| Fehér, KG | 1 |
| Kollin, E | 1 |
| Bodrogi, L | 1 |
| Bassi, F | 1 |
| Pupi, A | 1 |
| Giannotti, P | 1 |
| Fiorelli, G | 1 |
| Forti, G | 1 |
| Pinchera, A | 1 |
| Serio, M | 1 |
| Webb, SJ | 1 |
| Xiao, GH | 1 |
| Geoghegan, TE | 1 |
| Prough, RA | 1 |
| Bobyleva, V | 1 |
| Bellei, M | 1 |
| Kneer, N | 2 |
| Lardy, H | 2 |
| Tagawa, N | 2 |
| Tamanaka, J | 1 |
| Fujinami, A | 1 |
| Kobayashi, Y | 2 |
| Takano, T | 2 |
| Fukata, S | 2 |
| Kuma, K | 2 |
| Tada, H | 2 |
| Amino, N | 2 |
| Izumi, Y | 1 |
| Bicíková, M | 1 |
| Tallová, J | 1 |
| Hill, M | 1 |
| Vañuga, A | 1 |
| Putz, Z | 1 |
| Tomandl, J | 1 |
| Gerhard, I | 1 |
| Eggert-Kruse, W | 1 |
| Merzoug, K | 1 |
| Klinga, K | 1 |
| Runnebaum, B | 1 |
| Littley, MD | 1 |
| Pollock, A | 1 |
| Kane, J | 1 |
| Shalet, SM | 1 |
| Andó, S | 1 |
| Panno, ML | 1 |
| Beraldi, E | 1 |
| Tarantino, G | 1 |
| Salerno, M | 1 |
| Palmero, S | 1 |
| Prati, M | 1 |
| Fugassa, E | 1 |
| Bársony, J | 1 |
| Lakatos, P | 1 |
| Sneddon, A | 1 |
| Steel, JM | 1 |
| Strong, JA | 1 |
| Goldfine, I | 1 |
| Rosenfield, R | 1 |
| Landau, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antioxidants vs.Ovarian Bio-stimulation Therapy to Rescue the Ovarian Reserve[NCT03621683] | 78 participants (Actual) | Interventional | 2016-01-06 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for dehydroepiandrosterone and Hypothyroidism
| Article | Year |
|---|---|
Therapy of endocrine disease: Perspectives on the management of adrenal insufficiency: clinical insights from across Europe.
Topics: Addison Disease; Adrenal Insufficiency; Cardiovascular Diseases; Circadian Rhythm; Dehydroepiandrost | 2013 |
MECHANISMS IN ENDOCRINOLOGY: Aging and anti-aging: a Combo-Endocrinology overview.
Topics: Adjuvants, Immunologic; Aging; Androgens; Antioxidants; Circadian Rhythm; Dehydroepiandrosterone; Di | 2017 |
Hormonal causes of male sexual dysfunctions and their management (hyperprolactinemia, thyroid disorders, GH disorders, and DHEA).
Topics: Acromegaly; Adrenal Insufficiency; Dehydroepiandrosterone; Gonadotropins; Hormone Replacement Therap | 2013 |
19 other studies available for dehydroepiandrosterone and Hypothyroidism
| Article | Year |
|---|---|
[Endocrine disorders after combined chemoradiotherapy in Hodgkin Lymphoma survivors].
Topics: Adult; Chemoradiotherapy; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Hodgkin Dise | 2023 |
Impact of dehydroepiandrosterone on thyroid autoimmunity and function in men with autoimmune hypothyroidism.
Topics: Aged; Autoimmunity; Dehydroepiandrosterone; Humans; Hypothyroidism; Male; Thyroid Hormones; Thyrotro | 2021 |
Dehydroepiandrostenedione sulphate (DHEAS) levels predict high risk of rheumatoid arthritis (RA) in subclinical hypothyroidism.
Topics: Aged; Arthritis, Rheumatoid; Dehydroepiandrosterone; Female; Humans; Hypothyroidism; Male; Retrospec | 2021 |
Investigation of adrenal and thyroid gland dysfunction in dogs with ultrasonographic diagnosis of gallbladder mucocele formation.
Topics: Adrenal Glands; Adrenocortical Hyperfunction; Animals; Autoantibodies; Case-Control Studies; Dehydro | 2019 |
Immunoprotective steroids and SHBG in non-treated hypothyroidism and their relationship to autoimmune thyroid disorders.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoimmunity; Dehydroepiandrosterone; Female; Humans; Hy | 2008 |
Dehydroepiandrosterone sulphate (DS), dehydroepiandrosterone (D) and "free" dehydroepiandrosterone (FD) in the plasma of patients with thyroid diseases.
Topics: Adrenal Cortex; Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Graves Diseas | 1983 |
Plasma dehydroepiandrosterone sulphate in hypothyroid premenopausal women.
Topics: Adult; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hypothyroidism; Middle Aged; Prolacti | 1980 |
Regulation of CYP4A expression in rat by dehydroepiandrosterone and thyroid hormone.
Topics: Animals; Blotting, Northern; Blotting, Western; Cell Fractionation; Cells, Cultured; Cytochrome P-45 | 1996 |
The effects of the ergosteroid 7-oxo-dehydroepiandrosterone on mitochondrial membrane potential: possible relationship to thermogenesis.
Topics: Animals; Cell Respiration; Dehydroepiandrosterone; Glycerophosphates; Hyperthyroidism; Hypothyroidis | 1997 |
Thyroid hormone and dehydroepiandrosterone permit gluconeogenic hormone responses in hepatocytes.
Topics: Aminooxyacetic Acid; Animals; Calcium; Cyclic AMP; Dehydroepiandrosterone; Glucagon; Gluconeogenesis | 2000 |
Serum dehydroepiandrosterone, dehydroepiandrosterone sulfate, and pregnenolone sulfate concentrations in patients with hyperthyroidism and hypothyroidism.
Topics: Adult; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyperthyroidism; Hypo | 2000 |
Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism.
Topics: Adult; Androstenediol; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Hyper | 2001 |
Effect of treatment of hypothyroidism on the plasma concentrations of neuroactive steroids and homocysteine.
Topics: Adjuvants, Immunologic; Adult; Aged; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estradi | 2001 |
Thyrotropin-releasing hormone (TRH) and metoclopramide testing in infertile women.
Topics: Dehydroepiandrosterone; Dopamine Agents; Estradiol; Female; Fertilization; Follicle Stimulating Horm | 1991 |
Basal serum dehydroepiandrosterone sulphate concentration does not predict the cortisol response to provocative testing.
Topics: Adolescent; Adult; Aged; Cushing Syndrome; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; F | 1990 |
Influence of hypothyroidism on in-vitro testicular steroidogenesis in adult rats.
Topics: Androstenedione; Animals; Body Weight; Dehydroepiandrosterone; Dihydrotestosterone; Glucosephosphate | 1990 |
Effect of vitamin D3 loading and thyroid hormone replacement therapy on the decreased serum 25-hydroxyvitamin D level in patients with hypothyroidism.
Topics: Adolescent; Adult; Aged; Calcifediol; Cholecalciferol; Dehydroepiandrosterone; Dehydroepiandrosteron | 1986 |
Effect of thyroid funtion and of obesity on discriminant function for mammary carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androgens; Androsterone; Breast Neoplasms; | 1968 |
Hyperleydigism: a cause of severe pubertal gynecomastia.
Topics: 17-Ketosteroids; Adolescent; Dehydroepiandrosterone; Diabetes Insipidus; Estradiol; Feedback; Gyneco | 1971 |