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urea and Hypothyroidism

urea has been researched along with Hypothyroidism in 35 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Basal blood amino nitrogen concentrations (AAN), the urea nitrogen synthesis rate (UNSR) and the maximal hepatic capacity for urea nitrogen synthesis (CUNS) obtained during alanine infusion were determined together with N-contents in the soleus muscle and kidneys in experimentally hypothyroid rats (n = 19), upon thyroxine replacement (n = 14) and in experimentally hyperthyroid rats (n = 19)."7.69Hepatic amino nitrogen conversion and organ N-contents in hypothyroidism, with thyroxine replacement, and in hyperthyroid rats. ( Grøfte, T; Jensen, DS; Jørgensen, JO; Møller, N; Orskov, H; Vilstrup, H; Wolthers, T, 1997)
"Phorbol myristate acetate (PMA) inhibits glucagon-stimulated cyclic AMP accumulation and shifts to the right the dose-response curve to glucagon for ureagenesis."5.28Modulation of glucagon actions by phorbol myristate acetate in isolated hepatocytes. Effect of hypothyroidism. ( García-Sáinz, JA; Hernández-Sotomayor, SM; Hruby, VJ; Macías-Silva, M; Torres-Márquez, ME; Trivedi, D, 1990)
"Basal blood amino nitrogen concentrations (AAN), the urea nitrogen synthesis rate (UNSR) and the maximal hepatic capacity for urea nitrogen synthesis (CUNS) obtained during alanine infusion were determined together with N-contents in the soleus muscle and kidneys in experimentally hypothyroid rats (n = 19), upon thyroxine replacement (n = 14) and in experimentally hyperthyroid rats (n = 19)."3.69Hepatic amino nitrogen conversion and organ N-contents in hypothyroidism, with thyroxine replacement, and in hyperthyroid rats. ( Grøfte, T; Jensen, DS; Jørgensen, JO; Møller, N; Orskov, H; Vilstrup, H; Wolthers, T, 1997)
"Isolated hepatocytes from hypothyroid, euthyroid and hyperthyroid rats have been employed to investigate the relative importance of reducing-equivalent shuttles for the transfer of hydrogen between cytoplasm and mitochondria during simultaneous ureogenesis and gluconeogenesis."3.68Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status. ( Berry, MN; Gregory, RB; Phillips, JW, 1992)
" In an attempt to elucidate this important relationship, we have studied the effect of experimental hypo- and hyperthyroidism on urea biosynthesis and related processes."3.67Effect of thyroid hormones on urea biosynthesis and related processes in rat liver. ( Cabo, J; Jimenez-Nacher, I; Jorda, A; Marti, J; Portoles, M, 1988)
"Hypothyroidism was induced for 6 weeks by the administration of propylthiouracil in drinking water."1.39Biochemical and histopathological studies of the PTU-induced hypothyroid rat kidney with reference to the ameliorating role of folic acid. ( Hussein, WM; Ibrahim, W; Salama, AF; Tousson, E, 2013)
" The aim of this retrospective study was to evaluate the treatment of 83 hyperthyroid cats with 131I The dosage of 131I ranged from 4 to 6 milliCurie (mCi)."1.35[Treatment of feline hyperthyroidism with radioactive iodine-131]. ( Hof, AJ; van Dijl, IC, 2008)
"Phorbol myristate acetate (PMA) inhibits glucagon-stimulated cyclic AMP accumulation and shifts to the right the dose-response curve to glucagon for ureagenesis."1.28Modulation of glucagon actions by phorbol myristate acetate in isolated hepatocytes. Effect of hypothyroidism. ( García-Sáinz, JA; Hernández-Sotomayor, SM; Hruby, VJ; Macías-Silva, M; Torres-Márquez, ME; Trivedi, D, 1990)
"Renal compensatory hypertrophy is studied in age matched euthyroid and radiothyroidectomized female rats."1.26[Excretion of water, sodium, and potassium during the compensatory renal hypertrophy in hypothyroid rats]. ( Reville, P; Stephan, F, 1976)
"Distoritions of tase (dysgeusia) and smell (dysosmia) were frequent complaints among the untreated patients; dysgeusia was observed by 7 patients (39 per cent) and dysosmia by 3 patients (17 per cent)."1.25Defects of taste and smell in patients with hypothyroidism. ( Henkin, RI; McConnell, RJ; Menendez, CE; Rivlin, RS; Smith, FR, 1975)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199029 (82.86)18.7374
1990's4 (11.43)18.2507
2000's1 (2.86)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Salama, AF1
Tousson, E1
Ibrahim, W1
Hussein, WM1
van Dijl, IC1
Hof, AJ1
Pittman, JA1
Beschi, RJ1
Corvera, S2
Hernandez-Sotomayor, SM5
Garcia-Sainz, JA10
Pushpendran, CK1
Marchesini, G1
Fabbri, A1
Bianchi, GP1
Motta, E1
Bugianesi, E1
Urbini, D1
Pascoli, A1
Lodi, A1
Grøfte, T1
Wolthers, T1
Jensen, DS1
Møller, N1
Jørgensen, JO1
Orskov, H1
Vilstrup, H1
Barbosa-Saldivar, JL1
Van Itallie, TB1
Reville, P5
Stephan, F5
Pronina, NN1
Totrova, EA1
Belilova, FS1
McConnell, RJ1
Menendez, CE1
Smith, FR1
Henkin, RI1
Rivlin, RS1
Gregory, RB1
Phillips, JW1
Berry, MN1
Macías-Silva, M3
Torres-Márquez, ME1
Trivedi, D1
Hruby, VJ1
Müller, MJ1
Seitz, HJ1
Contreras-Rodríguez, JL3
Michel, B1
Marti, J1
Portoles, M1
Jimenez-Nacher, I1
Cabo, J1
Jorda, A1
Plebañski, M1
Huerta-Bahena, J1
Tussié-Luna, MI1
de la Garza, MC1
Nájera-Alvarado, A1
Jahn, H1
Porte, A1
Menahan, LA1
Wieland, O1
Holmes, EW1
DiScala, VA1
Russell, WC1
Eisinger, AJ1
Jones, NF1
Barraclough, MA1
McSwiney, RR1
Evered, DC1
Chapman, C1
Grillo, MA4
Coghe, M1
Cavallo, F1
Fossa, T3
Sategna-Guidetti, C1

Reviews

1 review available for urea and Hypothyroidism

ArticleYear
Semistarvation: an overview of an old problem.
    Bulletin of the New York Academy of Medicine, 1979, Volume: 55, Issue:8

    Topics: Adolescent; Adult; Amenorrhea; Animals; Anorexia Nervosa; Child; Edema; Female; Growth Hormone; Huma

1979

Trials

1 trial available for urea and Hypothyroidism

ArticleYear
Effect of vasopressin on the renal excretion of phosphate in man.
    Clinical science, 1970, Volume: 39, Issue:5

    Topics: Adult; Creatinine; Diuresis; Humans; Hypothyroidism; Kidney Tubules; Male; Phosphates; Urea; Vasopre

1970

Other Studies

33 other studies available for urea and Hypothyroidism

ArticleYear
Biochemical and histopathological studies of the PTU-induced hypothyroid rat kidney with reference to the ameliorating role of folic acid.
    Toxicology and industrial health, 2013, Volume: 29, Issue:7

    Topics: Analysis of Variance; Animals; Antioxidants; Creatinine; Folic Acid; Hypothyroidism; Kidney; Male; O

2013
[Treatment of feline hyperthyroidism with radioactive iodine-131].
    Tijdschrift voor diergeneeskunde, 2008, Jan-15, Volume: 133, Issue:2

    Topics: Animals; Cat Diseases; Cats; Creatinine; Female; Hyperthyroidism; Hypothyroidism; Iodine Radioisotop

2008
Taste thresholds in hyper- and hypothyroidism.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:6

    Topics: Addison Disease; Bicarbonates; Humans; Hydrochloric Acid; Hyperthyroidism; Hypothyroidism; Myxedema;

1967
Modulation by thyroid status of cyclic AMP-dependent and Ca2+-dependent mechanisms of hormone action in rat liver cells. Possible involvement of two different transduction mechanisms in alpha 1-adrenergic action.
    Biochimica et biophysica acta, 1984, Feb-17, Volume: 803, Issue:1-2

    Topics: Angiotensin II; Animals; Calcium; Cyclic AMP; Gluconeogenesis; Glycogen; Hyperthyroidism; Hypothyroi

1984
Effect of insulin on alpha1-adrenergic actions in hepatocytes from euthyroid and hypothyroid rats. Possible involvement of two pathways in alpha1-adrenergic actions.
    Biochemical and biophysical research communications, 1984, Jan-30, Volume: 118, Issue:2

    Topics: Animals; Epinephrine; Female; Glucagon; Hypothyroidism; Insulin; Kinetics; Liver; Liver Glycogen; Ph

1984
Hepatic conversion of amino nitrogen to urea nitrogen in hypothyroid patients and upon L-thyroxine therapy.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:10

    Topics: Adult; Alanine; Amino Acids; Female; Galactose; Homeostasis; Humans; Hypothyroidism; Linear Models;

1993
Hepatic amino nitrogen conversion and organ N-contents in hypothyroidism, with thyroxine replacement, and in hyperthyroid rats.
    Journal of hepatology, 1997, Volume: 26, Issue:2

    Topics: Animals; Body Weight; Female; Galactose; Heart Rate; Hyperthyroidism; Hypothyroidism; Liver; Rats; R

1997
[Excretion of water, sodium, and potassium during the compensatory renal hypertrophy in hypothyroid rats].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1976, Volume: 170, Issue:5

    Topics: Animals; Body Weight; Diuresis; Female; Glomerular Filtration Rate; Hypertrophy; Hypothyroidism; Kid

1976
[Role of hormones in the effects of vasopressin on the kidneys].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1976, Volume: 62, Issue:12

    Topics: Animals; Diabetes Mellitus, Experimental; Dogs; Hypothyroidism; Insulin; Kidney; Natriuresis; Norepi

1976
Defects of taste and smell in patients with hypothyroidism.
    The American journal of medicine, 1975, Volume: 59, Issue:3

    Topics: Adult; Aged; Dysgeusia; Female; Humans; Hydrochloric Acid; Hypothyroidism; Male; Middle Aged; Nitrob

1975
Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status.
    Biochimica et biophysica acta, 1992, Oct-06, Volume: 1137, Issue:1

    Topics: Alanine; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cytoplasm; Gluconeogenesis;

1992
Modulation of glucagon actions by phorbol myristate acetate in isolated hepatocytes. Effect of hypothyroidism.
    Cellular signalling, 1990, Volume: 2, Issue:3

    Topics: Animals; Bucladesine; Cyclic AMP; Dose-Response Relationship, Drug; Female; Glucagon; Hypothyroidism

1990
Interrelation between thyroid state and the effect of glucagon on gluconeogenesis in perfused rat livers.
    Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alanine; Aminoisobutyric Acids; An

1987
Effect of H-7 on the modulation of glucagon actions by activators of protein kinase-C.
    Biochemistry international, 1989, Volume: 18, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginine Vasopressin; Cells, Cultured; Drug

1989
Homologous beta-adrenergic desensitization in isolated rat hepatocytes.
    The Biochemical journal, 1987, Sep-01, Volume: 246, Issue:2

    Topics: Animals; Cyclic AMP; Female; Glucagon; Hypothyroidism; In Vitro Techniques; Isoproterenol; Liver; Pe

1987
Effect of thyroid hormones on urea biosynthesis and related processes in rat liver.
    Endocrinology, 1988, Volume: 123, Issue:5

    Topics: Amino Acids; Ammonia; Animals; Carbamoyl-Phosphate Synthase (Ammonia); Cyclic AMP; Glucagon; Glutama

1988
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
    Biochimica et biophysica acta, 1988, Dec-09, Volume: 972, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzym

1988
Possible existence of two mechanisms involved in alpha 1-adrenergic action: effect of Sgd 101/75.
    European journal of pharmacology, 1986, Jun-05, Volume: 125, Issue:1

    Topics: Adrenalectomy; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine;

1986
Possible involvement of two mechanisms of signal transduction in alpha 1-adrenergic action. Selective effect of cycloheximide.
    Biochimica et biophysica acta, 1985, Apr-22, Volume: 845, Issue:1

    Topics: Animals; Cycloheximide; Epinephrine; Female; Hypothyroidism; In Vitro Techniques; Insulin; Liver; Mo

1985
Insulin-like effect of epidermal growth factor in isolated rat hepatocytes. Modulation of the alpha-1-adrenergic stimulation of ureagenesis.
    Biochimica et biophysica acta, 1986, Nov-28, Volume: 889, Issue:2

    Topics: Animals; Epidermal Growth Factor; Epinephrine; Female; Hypothyroidism; Insulin; Liver; Rats; Rats, I

1986
Effects of histamine on the metabolism of isolated rat hepatocytes: roles of H1- and H2-histamine receptors.
    Molecular pharmacology, 1987, Volume: 31, Issue:3

    Topics: Animals; Calcium; Colforsin; Gluconeogenesis; Histamine; Hypothyroidism; Liver; Liver Glycogen; Pert

1987
[Comparative study of the effects of hyperthyroidism and hypothyroidism on output and concentration of rat urine].
    Archives internationales de physiologie et de biochimie, 1965, Volume: 73, Issue:1

    Topics: Animals; Hyperthyroidism; Hypothyroidism; Kidney; Polyuria; Potassium; Rats; Sodium; Thirst; Thyroxi

1965
[Determination of the intrarenal gradient of concentration of urea and sodium in hypothyroid rats and adrenalectomized rats].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1967, Volume: 161, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Animals; Hypothyroidism; Kidney; Rats; Sodium; Urea

1967
[Comparative study of the composition of plasma from hypothyroid and adrenalectoized rats].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1968, Oct-19, Volume: 162, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Chemical Analysis; Blood Glucose; Blood Proteins; Fema

1968
[Functional and ultrastructural study of the kidney of hypothyroid rats].
    Archives d'anatomie, d'histologie et d'embryologie normales et experimentales, 1968, Volume: 51, Issue:5

    Topics: Animals; Hypothyroidism; Kidney; Kidney Concentrating Ability; Kidney Glomerulus; Kidney Tubules; Pr

1968
The role of thyroid function in the metabolism of perfused rat liver with particular reference to gluconeogenesis.
    European journal of biochemistry, 1969, Volume: 10, Issue:1

    Topics: Animals; Body Weight; Carboxy-Lyases; Fasting; Glucagon; Gluconeogenesis; Hypothyroidism; Iodine Iso

1969
Studies on the exaggerated natriuretic response to a saline infusion in the hypothyroid rat.
    The Journal of clinical investigation, 1970, Volume: 49, Issue:6

    Topics: Aldosterone; Animals; Hypothyroidism; Infusions, Parenteral; Inulin; Iodine Radioisotopes; Kidney; K

1970
Hypothyroidism in a grizzly bear.
    Journal of the American Veterinary Medical Association, 1970, Sep-01, Volume: 157, Issue:5

    Topics: Animals; Carnivora; Dermatitis; Diet Therapy; Female; Gallbladder; Goiter; Hypothyroidism; Liver; Pe

1970
Plasma digoxin concentrations and digoxin toxicity in hospital patients.
    British heart journal, 1971, Volume: 33, Issue:4

    Topics: Administration, Oral; Adult; Age Factors; Aged; Arrhythmias, Cardiac; Coronary Disease; Digoxin; Ele

1971
Effect of thyroid hormones on some enzymes of nitrogen metabolism.
    Enzymologia, 1968, Dec-31, Volume: 35, Issue:6

    Topics: Ammonia; Animals; Antithyroid Agents; Aspartic Acid; Dactinomycin; Depression, Chemical; Diet; Ethio

1968
[On ureagenesis in the liver of the hypothyroid rat. Preliminary note].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Jul-31, Volume: 41, Issue:14

    Topics: Animals; Hypothyroidism; Liver; Rats; Urea

1965
[On ureagenesis in hypo- and hyperthyroidism. IV].
    Bollettino della Societa italiana di biologia sperimentale, 1966, Mar-15, Volume: 42, Issue:5

    Topics: Animals; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Liver; Rats; Urea

1966
Urea synthesis in the liver of the hypothyroid rat.
    Clinica chimica acta; international journal of clinical chemistry, 1966, Volume: 13, Issue:3

    Topics: Animals; Arginase; HLA-DR Antigens; HLA-DRB1 Chains; Hypothyroidism; In Vitro Techniques; Ligases; L

1966