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carbonyl cyanide p-trifluoromethoxyphenylhydrazone and Hypothyroidism

carbonyl cyanide p-trifluoromethoxyphenylhydrazone has been researched along with Hypothyroidism in 10 studies

Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone: A proton ionophore that is commonly used as an uncoupling agent in biochemical studies.
carbonyl cyanide p-trifluoromethoxyphenylhydrazone : A hydrazone that is hydrazonomalononitrile in which one of the hydrazine hydrogens is substituted by a p-trifluoromethoxyphenyl group.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"The effect of thyroid status on passive permeability of liver mitochondrial inner membrane was studied in euthyroid (EU), hyperthyroid (HYPER), hypothyroid (HYPO) rats and hypothyroid rats treated with a single dose of 3,3',5-triiodothyronine (HYPO + T3)."3.68Thyroid hormone effects on the proton permeability of rat liver mitochondria. ( Ecklund, RE; Horrum, MA; Tobin, RB, 1990)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's7 (70.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Severin, FF1
Severina, II1
Antonenko, YN1
Rokitskaya, TI1
Cherepanov, DA1
Mokhova, EN1
Vyssokikh, MY1
Pustovidko, AV1
Markova, OV1
Yaguzhinsky, LS1
Korshunova, GA1
Sumbatyan, NV1
Skulachev, MV1
Skulachev, VP2
Lombardi, A1
Lanni, A1
de Lange, P1
Silvestri, E1
Grasso, P1
Senese, R1
Goglia, F1
Moreno, M1
Horrum, MA4
Tobin, RB4
Ecklund, RE4
Herpin, P1
Berthon, D1
Duchamp, C1
Dauncey, MJ1
Le Dividich, J1
Bobyleva, V1
Pazienza, TL1
Maseroli, R1
Tomasi, A1
Salvioli, S1
Cossarizza, A1
Franceschi, C1
Gregory, RB1
Berry, MN1
Clay, VJ1
Ragan, CI1

Other Studies

10 other studies available for carbonyl cyanide p-trifluoromethoxyphenylhydrazone and Hypothyroidism

ArticleYear
Penetrating cation/fatty acid anion pair as a mitochondria-targeted protonophore.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-12, Volume: 107, Issue:2

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cat

2010
Acute administration of 3,5-diiodo-L-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria.
    FEBS letters, 2007, Dec-22, Volume: 581, Issue:30

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Respiration; Diiodothyronines; Ene

2007
Effects of 3,3',5-triiodo-L-thyronine (L-T3) and T3 analogues on mitochondrial function.
    Biochemistry and molecular biology international, 1995, Volume: 35, Issue:4

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cytochromes c1; Dactinomycin; Electron

1995
Effect of thyroid status in the perinatal period on oxidative capacities and mitochondrial respiration in porcine liver and skeletal muscle.
    Reproduction, fertility, and development, 1996, Volume: 8, Issue:1

    Topics: Animals; Animals, Newborn; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Electron Transport Co

1996
Effects of the novel thyroid hormone analogues, SKF L-94901, DIBIT, and 3'-AC-T2 on mitochondrial function.
    Biochemistry and molecular biology international, 1996, Volume: 38, Issue:1

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane; Diiodothyronines; Glycer

1996
Decrease in mitochondrial energy coupling by thyroid hormones: a physiological effect rather than a pathological hyperthyroidism consequence.
    FEBS letters, 1998, Jul-03, Volume: 430, Issue:3

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Energy Metabolism; Hyperthyroidism; Hyp

1998
The early triiodothyronine-induced changes in state IV respiration is not regulated by the proton permeability of the mitochondrial inner membrane.
    Biochemistry international, 1992, Volume: 28, Issue:5

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Dactinomycin; Glycerolphosphate Dehydro

1992
On the thyroid hormone-induced increase in respiratory capacity of isolated rat hepatocytes.
    Biochimica et biophysica acta, 1991, Dec-03, Volume: 1098, Issue:1

    Topics: Animals; Antimycin A; Atractyloside; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cult

1991
Thyroid hormone effects on the proton permeability of rat liver mitochondria.
    Molecular and cellular endocrinology, 1990, Jan-22, Volume: 68, Issue:2-3

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Hyperthyroidism; Hypothyroidism; In Vit

1990
Biosynthesis and import into the mitochondrion of L-3-glycerophosphate dehydrogenase, and the effect of thyroid hormone deficiency on gene expression.
    Biochimica et biophysica acta, 1989, Jun-23, Volume: 975, Issue:1

    Topics: Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cattle; Cell Line; Glycerolphosphate De

1989