Compounds > hydroxyproline
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hydroxyproline and Hypothyroidism

hydroxyproline has been researched along with Hypothyroidism in 47 studies

Hydroxyproline: A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
hydroxyproline : A proline derivative that is proline substituted by at least one hydroxy group.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Bone metabolism markers (bone alkaline phosphatase, ionized calcium, inorganic phosphorus, serum osteocalcin) and urinary excretion of hydroxyproline, Ca2+ and P after overnight fasting and of creatinine were studied in 52 female patients with endemic goiter and hypothyrosis (18 of these with decompensated hypothyrosis, 34 treated with thyroid hormones) and 48 women without thyroid diseases aged 45-60 years with menopause of no longer than 10 years (6."3.71[Calcium-phosphorus metabolism and bone metabolism in postmenopausal patients with the thyroid gland pathology]. ( Esedova, AE; Ferzilaeva, RA; Gadzhieva, MM, 2002)
"Changes in serum amino-terminal type III procollagen propeptide (PIIIPN) and hydroxyproline were compared with indices of thyroid function in 33 patients with hyperthyroidism and 16 patients with hypothyroidism before and after treatment."3.69Serum amino-terminal propeptide of type III procollagen in patients with hyperthyroidism or hypothyroidism during therapy. ( Jonderko, G; Jurecka-Tuleja, B; Kucharz, EJ; Marcisz, C, 1994)
" An increase of urinary excretion of hydroxyproline and hydroxylysine as well as concentration of these amino acids in blood serum was found in hyperthyroidism, and a decrease was shown in hyperthyroid guinea pigs."3.66Influence of thyroid hormones on collagen content in tissues of guinea pigs. ( Drózdzm, M; Grucka-Mamczar, E; Kucharz, E, 1979)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199040 (85.11)18.7374
1990's5 (10.64)18.2507
2000's2 (4.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BENOIT, FL1
THEIL, GB1
WATTEN, RH1
LEE, CA1
LLOYD, HM1
MALT, RA1
SCOTT, RB1
CHIUMELLO, G1
DELGUERCIO, MJ1
Douglas, N1
Olmedo, P1
Douglas, CR1
Monte, O1
Kivirikko, KI4
Laitinen, O3
Aer, J1
Halme, J1
Eisner, M1
Kondraciuk, A1
Kowalewski, K2
Yong, S2
Rico, H1
Cabranes, JA1
Paniagua, MC1
de Frutos, E1
Núñez-Torrón, M1
de Pablos, I1
Gómez-Castresana, F1
Bijlsma, JW1
Duursma, SA1
Roelofs, JM1
der Kinderen, PJ1
Frühbeck, G1
Cavallé, C1
Aragón, AM1
Muguerza, B1
Tosar, A1
Santidrián, S1
Kucharz, EJ1
Jurecka-Tuleja, B1
Jonderko, G1
Marcisz, C1
Erdoğan, M1
Ilhan, YS1
Akkuş, MA1
Caboğlu, SA1
Ozercan, I1
Ilhan, N1
Yaman, M1
Natori, J1
Shimizu, K1
Nagahama, M1
Tanaka, S1
Esedova, AE1
Gadzhieva, MM1
Ferzilaeva, RA1
Lamberg, BA3
Rosengård, S1
Liewendahl, K1
Saarinen, P1
Evered, DC1
Lisá, L1
Jansa, M1
Drózdzm, M1
Kucharz, E1
Grucka-Mamczar, E1
Pavlova, L1
Touliatos, J1
Lindholm, BW1
Castro, JH1
Genuth, SM1
Klein, L1
Krakauer, JC1
Kleerekoper, M1
Martinez, ME1
Herranz, L1
de Pedro, C1
Pallardo, LF1
Charles, P1
Poser, JW1
Mosekilde, L1
Jensen, FT1
Mäenpää, J1
Riviere, HB1
Reynolds, WA1
Wortsman, J1
Litvak, J1
Riesco, J1
Armendaris, R1
Rojas, A1
Fink, CW1
Ferguson, JL1
Smiley, JD1
Uitto, J1
Langness, U2
Eickenbusch, W2
Pak, CY1
Goncerzewicz, M1
Socha, J1
Cichy, W1
Nagadowska, J1
Teller, WM1
Genscher, U1
Burkhardt, H2
Rommel, K2
Ganea, E1
Ege, P1
Böhmer, T1
Wharton, BA1
Gough, G1
Williams, A1
Kitts, S1
Pennock, CA1
Ruiz-Torres, A1
Karstens, R1
Böhm, W1
Von Knorring, J1
Zatońska, I1
Widomska-Czekajska, T1
Zimmermann, J1
Rubegni, M1
Gennari, C1
Ravenni, G1
Forconi, S1
Bencini, M1
Banno', S1
Maggi, GC1
Buzzetti, A1

Reviews

3 reviews available for hydroxyproline and Hypothyroidism

ArticleYear
Parathyroid hormone and thyrocalcitonin: their mode of action and regulation.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Adenoma; Adenylyl Cyclases; Adult; Animals; Biological Transport; Bone and Bones; Bone Resorption; C

1971
[Urine hydroxyproline a review].
    Ugeskrift for laeger, 1968, Oct-17, Volume: 130, Issue:42

    Topics: Acromegaly; Bone Resorption; Carbon Isotopes; Collagen; Humans; Hydroxyproline; Hyperthyroidism; Hyp

1968
The biosynthesis of collagen.
    Acta rheumatologica Scandinavica, 1971, Volume: 17, Issue:3

    Topics: Acromegaly; Ascorbic Acid Deficiency; Carbon Isotopes; Collagen; Ehlers-Danlos Syndrome; Hydroxylati

1971

Other Studies

44 other studies available for hydroxyproline and Hypothyroidism

ArticleYear
HYDROXYPROLINE EXCRETION IN ENDOCRINE DISEASE.
    Metabolism: clinical and experimental, 1963, Volume: 12

    Topics: Acromegaly; Adolescent; Adrenocorticotropic Hormone; Aldosterone; Anabolic Agents; Cushing Syndrome;

1963
URINARY HYDROXYPROLINE IN DISEASES INVOLVING BONE AND CALCIUM METABOLISM.
    The Medical journal of Australia, 1964, Jun-27, Volume: 1

    Topics: Acute Kidney Injury; Alkaline Phosphatase; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Calcium;

1964
INFLUENCE OF THYROXINE ON THE RIBOSOMAL SYNTHESIS OF COLLAGEN.
    Surgical forum, 1964, Volume: 15

    Topics: Animals; Ascorbic Acid; Collagen; Guinea Pigs; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Meta

1964
[MODIFICATONS OF HYDROXYPROLINURIA IN TREATMENT OF HYPOTHYROIDISM AND HYPOPITUITARY NANISM].
    Minerva pediatrica, 1965, Jun-16, Volume: 17

    Topics: Adolescent; Child; Congenital Hypothyroidism; Dwarfism; Dwarfism, Pituitary; Humans; Hydroxyproline;

1965
[Influence of propyl-thiouracil-induced hypothyroidism on rat gingival mucosa].
    Arquivos brasileiros de endocrinologia e metabologia, 2006, Volume: 50, Issue:5

    Topics: Animals; Antithyroid Agents; Collagen; Colorimetry; Disease Models, Animal; DNA; Gingiva; Hydroxypro

2006
Metabolism of collagen in experimental hyperthyroidism and hypothyroidism in the rat.
    Endocrinology, 1967, Volume: 80, Issue:6

    Topics: Animals; Carbon Isotopes; Collagen; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Male; Proline;

1967
[Clinical evaluation of serum and urinary proline and hydroxyproline determination in thyroid diseases].
    Polskie Archiwum Medycyny Wewnetrznej, 1967, Volume: 38, Issue:5

    Topics: Adult; Chromatography, Paper; Female; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Male;

1967
Hydroxyproline in healing dermal wounds of normal and hypothyroid rats.
    Acta endocrinologica, 1967, Volume: 54, Issue:1

    Topics: Animals; Collagen; Hydroxyproline; Hypothyroidism; In Vitro Techniques; Rats; Skin; Wound Healing

1967
Bone and urinary hydroxyproline in normal and hypothyroid rat with a long bone fracture.
    Acta endocrinologica, 1967, Volume: 56, Issue:3

    Topics: Animals; Body Weight; Bone and Bones; Collagen; Humeral Fractures; Hydroxyproline; Hypothyroidism; M

1967
[Is phosphodiesterase responsible for bone changes in thyroid dysfunction?].
    Medicina clinica, 1983, Nov-19, Volume: 81, Issue:16

    Topics: Bone Diseases, Metabolic; Female; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Male; Par

1983
Thyroid function and bone turnover.
    Acta endocrinologica, 1983, Volume: 104, Issue:1

    Topics: Acid Phosphatase; Adult; Aged; Alkaline Phosphatase; Bone and Bones; Calcitriol; Calcium; Creatinine

1983
Effect of thyroxine on the rate of collagen breakdown in young thyroidectomized male rats.
    Revista espanola de fisiologia, 1994, Volume: 50, Issue:2

    Topics: Animals; Body Weight; Collagen; Hydroxyproline; Hypothyroidism; Liver; Male; Muscles; Organ Size; Ra

1994
Serum amino-terminal propeptide of type III procollagen in patients with hyperthyroidism or hypothyroidism during therapy.
    Thyroid : official journal of the American Thyroid Association, 1994,Summer, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Female; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Male; Methimazol

1994
Effects of L-thyroxine and zinc therapy on wound healing in hypothyroid rats.
    Acta chirurgica Belgica, 1999, Volume: 99, Issue:2

    Topics: Animals; Hormone Replacement Therapy; Hydroxyproline; Hypothyroidism; Rats; Thyroxine; Wound Healing

1999
The influence of hypothyroidism on wound healing. An experimental study.
    Nihon Ika Daigaku zasshi, 1999, Volume: 66, Issue:3

    Topics: Animals; Biomarkers; Collagen; Disease Models, Animal; Hydroxyproline; Hypothyroidism; Male; Rats; R

1999
[Calcium-phosphorus metabolism and bone metabolism in postmenopausal patients with the thyroid gland pathology].
    Klinicheskaia laboratornaia diagnostika, 2002, Issue:3

    Topics: Alkaline Phosphatase; Bone and Bones; Calcitonin; Calcium; Female; Goiter, Endemic; Humans; Hydroxyp

2002
Familial partial peripheral resistance to thyroid hormones.
    Acta endocrinologica, 1978, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Female; Goiter; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Male; Mi

1978
[Excretion of hydroxyproline--a fast acting symptom of bone metabolism].
    Ceskoslovenska pediatrie, 1975, Volume: 30, Issue:1-2

    Topics: Bone and Bones; Child; Female; Humans; Hydroxyproline; Hypophosphatemia, Familial; Hypothyroidism; I

1975
Influence of thyroid hormones on collagen content in tissues of guinea pigs.
    Endokrinologie, 1979, Volume: 73, Issue:1

    Topics: Animals; Bone and Bones; Collagen; Guinea Pigs; Hydroxylysine; Hydroxyproline; Hyperthyroidism; Hypo

1979
[Studies of calcium-phosphorus metabolism in thyrotoxicosis].
    Vutreshni bolesti, 1977, Volume: 16, Issue:4

    Topics: Adult; Calcium; Female; Humans; Hydroxyproline; Hypercalcemia; Hyperthyroidism; Hypothyroidism; Male

1977
Treatment of acromegaly by transsphenoidal hypophysectomy with cryoapplication.
    Clinical endocrinology, 1975, Volume: 4, Issue:1

    Topics: Acromegaly; Adrenal Insufficiency; Adult; Calcium; Cerebrospinal Fluid Rhinorrhea; Cryosurgery; Diab

1975
Comparative response to parathyroid hormone in hyperthyroidism and hypothyroidism.
    Metabolism: clinical and experimental, 1975, Volume: 24, Issue:7

    Topics: Adult; Aged; Alkaline Phosphatase; Antigens; Bone and Bones; Calcium; Female; Humans; Hydroxyproline

1975
Borderline-low serum thyrotropin level is correlated with increased fasting urinary hydroxyproline excretion.
    Archives of internal medicine, 1992, Volume: 152, Issue:2

    Topics: Aged; Bone Diseases, Metabolic; Calcium; Creatinine; Fasting; Female; Humans; Hydroxyproline; Hyperp

1992
Osteocalcin levels in patients with hyper- and hypothyroidism.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1986, Volume: 18, Issue:3

    Topics: Adult; Alkaline Phosphatase; Calcium-Binding Proteins; Female; Humans; Hydroxyproline; Hyperthyroidi

1986
Estimation of bone turnover evaluated by 47Ca-kinetics. Efficiency of serum bone gamma-carboxyglutamic acid-containing protein, serum alkaline phosphatase, and urinary hydroxyproline excretion.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:6

    Topics: Adult; Aged; Alkaline Phosphatase; Bone and Bones; Bone Resorption; Calcification, Physiologic; Calc

1985
Juvenile goitrous autoimmune thyroiditis.
    Acta paediatrica Scandinavica, 1972, Volume: 61, Issue:1

    Topics: Adolescent; Age Factors; Antibodies, Anti-Idiotypic; Autoanalysis; Autoimmune Diseases; Biopsy; Bloo

1972
Hydroxyproline content of the tadpole tail in response to hypothyroidism.
    Comparative biochemistry and physiology. A, Comparative physiology, 1974, Feb-01, Volume: 47, Issue:2

    Topics: Animals; Collagen; Hydroxyproline; Hypophysectomy; Hypothyroidism; Larva; Metamorphosis, Biological;

1974
[Urinary hydroxyproline as an indicator of thyroid function activity].
    Revista medica de Chile, 1967, Volume: 95, Issue:7

    Topics: Adult; Biomarkers; Bone Resorption; Female; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism;

1967
Value of urine and serum hydroxyproline in the diagnosis of thyroid disease.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aged; Antithyroid Agents; Blood; Child; Child, Preschool; Female; Humans; Hydroxy

1965
Effect of hyperthyroidism and hypothyroidism on collagen metabolism.
    The Journal of laboratory and clinical medicine, 1967, Volume: 69, Issue:6

    Topics: Aging; Animals; Antithyroid Agents; Bone and Bones; Carbon Isotopes; Collagen; Hydroxyproline; Hyper

1967
Further evaluation of the significance of urinary hydroxyproline determinations in the diagnosis of thyroid disorders.
    Clinica chimica acta; international journal of clinical chemistry, 1968, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Collagen; Goiter; Graves Disease; Humans; Hydroxyp

1968
[Hydroxyproline determination in the urine for diagnosis of thyroid function].
    Medizinische Klinik, 1969, Jun-13, Volume: 64, Issue:24

    Topics: Cholesterol; Goiter; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Thyroid Diseases; Thyr

1969
[Hydroxyproline indicators in the evaluation of nutritional status of children with various metabolic diseases].
    Pediatria polska, 1974, Volume: 49, Issue:2

    Topics: Child; Child Nutrition Disorders; Diabetes Mellitus, Type 1; Endocrine System Diseases; Female; Huma

1974
Hydroxyproline excretion in various forms of growth failure.
    Archives of disease in childhood, 1973, Volume: 48, Issue:2

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Diagnosis, Differential; Dwarfism; Dwarfism

1973
[Collagen in endocrine diseases with bone involvement].
    Studii si cercetari de endocrinologie, 1973, Volume: 24, Issue:6

    Topics: Acromegaly; Bone and Bones; Bone Diseases; Collagen; Collagen Diseases; Dwarfism, Pituitary; Endocri

1973
Urinary total hydroxyproline: creatinine ratio. Range of normal, and clinical application in British children.
    Archives of disease in childhood, 1972, Volume: 47, Issue:251

    Topics: Adolescent; Anthropometry; Autoanalysis; Celiac Disease; Child; Child, Preschool; Congenital Hypothy

1972
[Clinical significance of the determination of hydroxyprolinuria].
    Die Medizinische Welt, 1969, Oct-04, Volume: 40

    Topics: Bone Diseases; Diabetes Mellitus; Diagnosis, Differential; Endocarditis; Female; Humans; Hydroxyprol

1969
[Urinary hydroxyproline and the metabolism of collagen].
    Duodecim; laaketieteellinen aikakauskirja, 1969, Volume: 85, Issue:18

    Topics: Acromegaly; Bone Diseases; Child; Collagen; Collagen Diseases; Dwarfism, Pituitary; Humans; Hydroxyp

1969
[Diagnosis of thyroid function by means of measurement of collagen turnover].
    Die Medizinische Welt, 1969, Nov-15, Volume: 46

    Topics: Collagen; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Thyroid Function Tests

1969
Myocardial collagen in hyper- and hypothyroid rats and guinea-pigs.
    Annales medicinae experimentalis et biologiae Fenniae, 1970, Volume: 48, Issue:1

    Topics: Animals; Body Weight; Collagen; Guinea Pigs; Heart; Hydroxyproline; Hyperthyroidism; Hypothyroidism;

1970
[Blood and urinary hydroxyproline levels in patients with hyperthyroidism and hypothyroidism].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1970, Volume: 25, Issue:36

    Topics: Adolescent; Adult; Aged; Female; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Male; Midd

1970
[Determination of amino acids in plasma and urine for the functional diagnosis of the thyroid gland].
    Medizinische Klinik, 1971, Jan-01, Volume: 66, Issue:1

    Topics: Amino Acids; Diagnosis, Differential; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Iodin

1971
[Hydroxyprolinuria in thyroid diseases].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Apr-15, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Aged; Collagen; Humans; Hydroxyproline; Hyperthyroidism; Hypothyroidism; Middle A

1965
[Metabolism of collagen and hydroxprolinuria in thyroid diseases].
    Il Policlinico. Sezione pratica, 1966, Nov-21, Volume: 73, Issue:47

    Topics: Adult; Alkaline Phosphatase; Calcium; Collagen; Female; Humans; Hydroxyproline; Hyperthyroidism; Hyp

1966