papaverine has been researched along with Hypothyroidism in 5 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1 The effect of hypothyroidism, induced by methimazole, upon the response of the isolated portal vein of the rat to adrenoceptor agonists and antagonists, to angiotensin II and to papaverine has been investigated." | 3.66 | Adrenoreceptor-mediated responses in the isolated portal vein of the hypothyroid rat. ( Handberg, GM; Ishac, EJ; Pennefather, JN; Story, ME; Yoong, YL, 1982) |
| "Hypothyroidism has been reported to occur in 6% of impotent men." | 1.33 | Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits. ( Bagcivan, I; Kaya, K; Kilicarslan, H; Sarac, B; Yildirim, MK; Yildirim, S, 2006) |
| "Hypothyroidism has been reported to occur in 6% of impotent men." | 1.33 | Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits. ( Bagcivan, I; Kaya, T; Kilicarslan, H; Sarac, B; Yildirim, MK, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sarac, B | 2 |
| Yildirim, MK | 2 |
| Bagcivan, I | 2 |
| Kaya, K | 1 |
| Kilicarslan, H | 2 |
| Yildirim, S | 1 |
| Kaya, T | 1 |
| Hagino, Y | 1 |
| Uematsu, T | 1 |
| Tachibana, M | 1 |
| Tsuru, H | 1 |
| Oguro, K | 1 |
| Ohguchi, S | 1 |
| Nakashima, M | 1 |
| Yoong, YL | 1 |
| Story, ME | 1 |
| Ishac, EJ | 1 |
| Pennefather, JN | 1 |
| Handberg, GM | 1 |
5 other studies available for papaverine and Hypothyroidism
| Article | Year |
|---|---|
Effect of hypothyroidism on the nitrergic relaxant responses of corpus cavernosal smooth muscle in rabbits.
Topics: Animals; Carbachol; Cholinergic Agonists; Disease Models, Animal; Electric Stimulation; Hypothyroidi | 2006 |
Effect of hypothyroidism on the NO/cGMP pathway of corpus cavernosum in rabbits.
Topics: Animals; Carbachol; Cyclic GMP; Disease Models, Animal; Electric Stimulation; Hypothyroidism; Impote | 2006 |
Effect of thyroid hormone on cyclic AMP phosphodiesterase in rat kidney.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Hypothyroidism; In Vitro | 1980 |
Induction of opposite response of hindlimb vasculature to adrenergic agents in hypothyroid rats.
Topics: Acetylcholine; Animals; Blood Pressure; Clonidine; Heart Rate; Hindlimb; Hypothyroidism; In Vitro Te | 1984 |
Adrenoreceptor-mediated responses in the isolated portal vein of the hypothyroid rat.
Topics: Angiotensin II; Animals; Hypothyroidism; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; P | 1982 |