Page last updated: 2024-10-29

imipramine and Hypothyroidism

imipramine has been researched along with Hypothyroidism in 11 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"A case report is presented of an adolescent male who developed hypothyroidism and cardiomyopathy 6 months after he began taking lithium and imipramine for a severe conduct disorder."3.68Cardiac toxicity in an adolescent following chronic lithium and imipramine therapy. ( Dietrich, A; Mortensen, ME; Wheller, J, 1993)
"Narcolepsy may affect as many as 200,000 Americans."1.26Narcolepsy. Diagnosis and treatment. ( Carskadon, MA; Dement, WC; Guilleminault, C; Zarcone, VP, 1976)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19909 (81.82)18.7374
1990's2 (18.18)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PRANGE, AJ2
LIPTON, MA1
LOVE, GN1
KLEIN, JJ1
SEGAL, RL1
WARNER, RR1
Dietrich, A1
Mortensen, ME1
Wheller, J1
Dement, WC1
Carskadon, MA1
Guilleminault, C1
Zarcone, VP1
Sandrini, M1
Marrama, D1
Vergoni, AV1
Bertolini, A1
Martin, P1
Massol, J1
Belon, JP1
Gaudel, G1
SoubriƩ, P1
Rogers, MP1
Whybrow, PC1
Colantonio, LA1
Orson, JM1
Avni, J1
Edelstein, EL1
Khazan, N1
Sulman, FG1
Winter, D1

Other Studies

11 other studies available for imipramine and Hypothyroidism

ArticleYear
Diminution of imipramine mortality in hypothyroid mice.
    Nature, 1963, Mar-23, Volume: 197

    Topics: Animals; Hypothyroidism; Imipramine; Mice

1963
THE PHARMACOLOGY AND BIOCHEMISTRY OF DEPRESSION.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Amitriptyline; Antidepressive Agents; Biochemical Phenomena; Biochemistry; Brain; Depression; Depres

1964
GALACTORRHEA DUE TO IMIPRAMINE. REPORT OF A CASE.
    The New England journal of medicine, 1964, Sep-03, Volume: 271

    Topics: Amenorrhea; Chlorpromazine; Depression; Depressive Disorder; Female; Galactorrhea; Humans; Hypothyro

1964
Cardiac toxicity in an adolescent following chronic lithium and imipramine therapy.
    The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 1993, Volume: 14, Issue:5

    Topics: Adolescent; Cardiac Complexes, Premature; Cardiomyopathies; Child; Child Behavior Disorders; Drug Th

1993
Narcolepsy. Diagnosis and treatment.
    Primary care, 1976, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Behavior; Cataplexy; Child; Diagnosis, Differential; Female; Humans; Hypoglycemia

1976
Effects of thyroid status on the characteristics of alpha 1-, alpha 2-, beta, imipramine and GABA receptors in the rat brain.
    Life sciences, 1991, Volume: 48, Issue:7

    Topics: Animals; Brain; Dihydroalprenolol; Hyperthyroidism; Hypothyroidism; Imipramine; Kinetics; Male; Musc

1991
Thyroid function and reversal by antidepressant drugs of depressive-like behavior (escape deficits) in rats.
    Neuropsychobiology, 1987, Volume: 18, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Clomipramine; Desipramine; Dose-Response Relationship, Drug;

1987
Clinical hypothyroidism occurring during lithium treatment: two case histories and a review of thyroid function in 19 patients.
    The American journal of psychiatry, 1971, Volume: 128, Issue:2

    Topics: Adolescent; Adult; Bipolar Disorder; Female; Humans; Hypothyroidism; Imipramine; Lithium; Male; Midd

1971
Triiodothyronine thyrotoxicosis. Induction by desiccated thyroid and imipramine.
    American journal of diseases of children (1960), 1974, Volume: 128, Issue:3

    Topics: Child; Congenital Hypothyroidism; Drug Synergism; Enuresis; Female; Humans; Hyperthyroidism; Hypothy

1974
Comparative study of imipramine, amitriptyline and their desmethyl analogues in the hypothyroid rat.
    Psychopharmacologia, 1967, Volume: 10, Issue:5

    Topics: Amitriptyline; Animals; Blepharoptosis; Desipramine; Exploratory Behavior; Female; Hypothyroidism; I

1967
[Experimental contribution to the role of the thyroid gland in modification of reactivity of the body to medication. Modification of the toxicity of some psychotropic drugs in animals with induced hyperthyroidism and hypothyroidism].
    Studii si cercetari de endocrinologie, 1966, Volume: 17, Issue:5

    Topics: Amphetamine; Animals; Chlordiazepoxide; Drug Hypersensitivity; Hyperthyroidism; Hypothyroidism; Imip

1966