Page last updated: 2024-11-04

sulpiride and Hypothyroidism

sulpiride has been researched along with Hypothyroidism in 4 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
" In order to study the effect of thyroid hormones on the activity of hypothalamic dopamine neurons, lactotrophs and thyrotrophs, we administered increasing doses of thyroid hormones to patients with primary hypothyroidism, and examined the changes of basal PRL, TSH and PRL responses to a dopamine receptor blocker (sulpiride)."3.67Enhanced prolactin secretion in patients with primary hypothyroidism during thyroid replacement. ( Fukazawa, H; Hanew, K; Murakami, O; Saito, S; Sakurada, T; Sasaki, A; Sato, S; Shimizu, Y; Yoshinaga, K, 1984)
" sulpiride (a dopamine-receptor-blocking drug) led to a significant rise in plasma TSH in normal womem, in female patients with galactorrhoea, and, to a much more marked degree, in male and female patients with primary hypothyroidism."3.66Increased thyrotrophin secretion induced by sulpiride in man. ( Belforte, L; Camanni, F; Massara, F; Molinatti, GM; Vergano, V, 1978)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mendhekar, DN1
Andrade, C1
Sato, S1
Hanew, K1
Sasaki, A1
Shimizu, Y1
Murakami, O1
Fukazawa, H1
Sakurada, T1
Saito, S1
Yoshinaga, K1
Massara, F1
Camanni, F1
Belforte, L1
Vergano, V1
Molinatti, GM1
Sandyk, R1

Other Studies

4 other studies available for sulpiride and Hypothyroidism

ArticleYear
Amisulpride-induced tardive dyskinesia and possible association of dyskinesia with hypothyroidism.
    The Journal of neuropsychiatry and clinical neurosciences, 2009,Winter, Volume: 21, Issue:1

    Topics: Amisulpride; Dopamine Antagonists; Dyskinesia, Drug-Induced; Humans; Hypothyroidism; Male; Sulpiride

2009
Enhanced prolactin secretion in patients with primary hypothyroidism during thyroid replacement.
    The Tohoku journal of experimental medicine, 1984, Volume: 144, Issue:4

    Topics: Adult; Aged; Female; Humans; Hypothyroidism; Male; Middle Aged; Prolactin; Sulpiride; Thyroid Hormon

1984
Increased thyrotrophin secretion induced by sulpiride in man.
    Clinical endocrinology, 1978, Volume: 9, Issue:5

    Topics: Adolescent; Adult; Female; Galactorrhea; Humans; Hypothyroidism; Male; Middle Aged; Pregnancy; Prola

1978
Tardive dyskinesia induced by sulpiride in a patient with hypothyroidism.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:1

    Topics: Aged; Dyskinesia, Drug-Induced; Female; Humans; Hypothyroidism; Sulpiride

1986