1-methyl-3-isobutylxanthine has been researched along with Hypothyroidism in 4 studies
1-Methyl-3-isobutylxanthine: A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
3-isobutyl-1-methylxanthine : An oxopurine that is xanthine which is substituted at positions 1 and 3 by methyl and isobutyl groups, respectively.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hagino, Y | 1 |
| Uematsu, T | 1 |
| Tachibana, M | 1 |
| Tsuru, H | 1 |
| Elks, ML | 1 |
| Manganiello, VC | 1 |
| Al-Turk, WA | 1 |
| Shaheen, O | 1 |
| Othman, S | 1 |
| Müller, MJ | 1 |
| Seitz, HJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thyroid Hormone-Induced Lipolysis: An In Vivo Microdialysis Study[NCT00312715] | 41 participants (Actual) | Observational | 2006-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for 1-methyl-3-isobutylxanthine and Hypothyroidism
| Article | Year |
|---|---|
Effect of thyroid hormone on cyclic AMP phosphodiesterase in rat kidney.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Hypothyroidism; In Vitro | 1980 |
Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue; | 1985 |
Effect of forskolin on cAMP accumulation and ketogenesis in isolated hepatocytes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Colforsin; Cyclic AMP; Glucagon; Hypothyroidism; In Vitro Tech | 1986 |
Interrelation between thyroid state and the effect of glucagon on gluconeogenesis in perfused rat livers.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alanine; Aminoisobutyric Acids; An | 1987 |