Page last updated: 2024-10-24

verapamil and Hypothyroidism

verapamil has been researched along with Hypothyroidism in 8 studies

Verapamil: A calcium channel blocker that is a class IV anti-arrhythmia agent.
verapamil : A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine.
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile : A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Aim of this study was to investigate antiarrhythmic and toxic effects of verapamil in mice and rats with thyrotoxicosis and hypothyroidism."7.74[Characteristics of pharmacological and toxic effects of verapamil during cardiac arrhythmia in thyrotoxic and hypothyroid rats]. ( Afanas'eva, EIu; Arzamastsev, EV; Sokhanenkov, MIu; Sokhanenkova, AE, 2008)
"In some patients with severe hypothyroidism, thyroxine replacement therapy precipitates or aggravates angina pectoris, whereas in other patients angina pectoris is ameliorated or even cured."7.68Cardiac left ventricular function before and during early thyroxine treatment in severe hypothyroidism. ( Bernstein, R; Haug, E; Hertzenberg, L; Kjørstad, KE; Midtbø, K; Müller, C; Nakken, KF, 1991)
"Aim of this study was to investigate antiarrhythmic and toxic effects of verapamil in mice and rats with thyrotoxicosis and hypothyroidism."3.74[Characteristics of pharmacological and toxic effects of verapamil during cardiac arrhythmia in thyrotoxic and hypothyroid rats]. ( Afanas'eva, EIu; Arzamastsev, EV; Sokhanenkov, MIu; Sokhanenkova, AE, 2008)
"In some patients with severe hypothyroidism, thyroxine replacement therapy precipitates or aggravates angina pectoris, whereas in other patients angina pectoris is ameliorated or even cured."3.68Cardiac left ventricular function before and during early thyroxine treatment in severe hypothyroidism. ( Bernstein, R; Haug, E; Hertzenberg, L; Kjørstad, KE; Midtbø, K; Müller, C; Nakken, KF, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sokhanenkova, AE1
Sokhanenkov, MIu1
Afanas'eva, EIu1
Arzamastsev, EV1
Andersson, DE1
Röjmark, S1
Veksler, VI1
Levitskaya, EL1
Khatkevich, AN1
Orekhova, IV1
Khuchua, ZA1
Kapelko, VI1
Doughty, JC1
Donald, AK1
Keogh, G1
Cooke, TG1
Seppet, EK1
Kolar, F1
Dixon, IM1
Hata, T1
Dhalla, NS1
Bernstein, R1
Müller, C1
Midtbø, K1
Haug, E1
Nakken, KF1
Hertzenberg, L1
Kjørstad, KE1
Hagino, Y1
Nomura, H1
Nomura, T1
Maekawa, H1
Izuhara, K1
Tachibana, M1
De Marinis, L1
Mancini, A1
Minnielli, S1
D'Amico, C1
Di Pietro, ML1
Albini, C1
Passeri, M1
Liberale, I1
Menini, E1
Barbarino, A1

Other Studies

8 other studies available for verapamil and Hypothyroidism

ArticleYear
[Characteristics of pharmacological and toxic effects of verapamil during cardiac arrhythmia in thyrotoxic and hypothyroid rats].
    Kardiologiia, 2008, Volume: 48, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dose-Response Relatio

2008
Effect of verapamil on blood glucose and serum insulin in patients with hyper- and hypothyroidism.
    Acta medica Scandinavica, 1980, Volume: 208, Issue:5

    Topics: Adult; Aged; Blood Glucose; Female; Humans; Hyperthyroidism; Hypothyroidism; Insulin; Male; Middle A

1980
Myocardial adaptation to long-term action of substances associated with decreased intensity of cardiac function.
    Biochemical medicine and metabolic biology, 1994, Volume: 53, Issue:1

    Topics: Adaptation, Physiological; Adenosine Triphosphatases; Animals; Body Weight; Calcium; Heart; Hypothyr

1994
Stercoral perforation with verapamil.
    Postgraduate medical journal, 1994, Volume: 70, Issue:825

    Topics: Aged; Chronic Disease; Constipation; Female; Humans; Hypothyroidism; Intestinal Perforation; Sigmoid

1994
Regulation of cardiac sarcolemmal Ca2+ channels and Ca2+ transporters by thyroid hormone.
    Molecular and cellular biochemistry, 1993, Dec-22, Volume: 129, Issue:2

    Topics: Animals; Calcium Channels; Calcium-Binding Proteins; Heart; Hyperthyroidism; Hypothyroidism; In Vitr

1993
Cardiac left ventricular function before and during early thyroxine treatment in severe hypothyroidism.
    Journal of internal medicine, 1991, Volume: 230, Issue:6

    Topics: Adult; Aged; Exercise Test; Female; Gated Blood-Pool Imaging; Humans; Hypothyroidism; Male; Middle A

1991
The role of calcium ion in methoxamine-induced amylase release from parotid glands of euthyroid and hypothyroid rats.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:1

    Topics: Adrenergic alpha-Agonists; Amylases; Animals; Calcium; Calmodulin; Hypothyroidism; Male; Methoxamine

1985
Calcium antagonists and hormone release. V. Effects of a calcium-antagonist (verapamil) on pituitary hormone release in hypersecretory states.
    Hormone research, 1987, Volume: 25, Issue:1

    Topics: Acromegaly; Adolescent; Adult; Cushing Syndrome; Female; Humans; Hypogonadism; Hypothyroidism; Male;

1987