Page last updated: 2024-11-11

clopenthixol acetate ester

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

clopenthixol acetate ester: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6436640
CHEBI ID135722
SCHEMBL ID1651216
MeSH IDM0167711

Synonyms (20)

Synonym
AKOS015841102
(z)-4-(3-(2-chloro-9h-thioxanthen-9-ylidene)propyl)piperazine-1-ethyl acetate
clopenthixol acetate ester
einecs 288-415-5
CHEBI:135722
zuclopenthixol acetate
D08691
cisordinol-acutard (tn)
85721-05-7
2-[4-[(3z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethyl acetate
clopixol-acuphase
(z)-4-(3-(2-chlorothioxanthen-9-ylidene)propyl)-1-piperazineethanol acetate
clopixol acuphase
unii-349s2zhf05
349s2zhf05 ,
zuclopenthixol acetate [mart.]
zuclopenthixol acetate [who-dd]
SCHEMBL1651216
DTXSID00235032
Q27256348

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" The pharmacokinetic profiles of the three injectable zuclopenthixol preparations are very different."( Pharmacokinetics of three different injectable zuclopenthixol preparations.
Aaes-Jørgensen, T, 1989
)
0.28

Dosage Studied

ExcerptRelevanceReference
" The dosage ranged from 50 mg to 100 mg."( Zuclopenthixol acetate in viscoleo in acutely disturbed psychotic patients.
Barr, F; Schlosberg, A, 1991
)
0.28
" The mean dosage of zuclopenthixol acetate by injection, foreseen in the protocol, was between 126 to 138 mg."( [Efficacy of zuclopenthixol acetate on psychotic anxiety evaluated in an open study].
Benyaya, J; Dermain, P; Greslé, P; Grignon, S; Moisan, P; Nore, D; Pech, G; Perret, I; Romain, JL,
)
0.13
" Age, sex, psychiatric and somatic diagnoses, body mass index (BMI), dosage and duration of Zuclopenthixol-acetate medication and the timing of the changeover from intramuscular to oral prescription, the single dosage of Clopenthixol if initially coadministered, incidence, onset and duration of transient benign hyperthermia, iron, ferritin, transferrin and saturation values, and white and red blood cell counts as well as liver function and electrolytes were registered."( Zuclopenthixol-acetate treatment in catatonic patients: the implication of iron metabolism.
Bertsch, E; Conca, A; Hansen, M; Hrubos, W; König, P; Küng, A; Waschgler, R, 2003
)
0.32
" This dosage should be varied depending on health, age, and temperament of the individual cheetah."( Evaluation of long-term sedation in cheetah (Acinonyx jubatus) with perphenazine enanthate and zuclopenthixol acetate.
Huber, C; Slotta-Bachmayr, L; Walzer, C, 2001
)
0.31
" No significant differences were found in the rate of violent behavior and antipsychotic dosage at discharge."( Olanzapine intramuscular shows better efficacy than zuclopenthixol acetate intramuscular in reducing the need for restraint, but not in comparison to haloperidol intramuscular.
Bloemhof-Bris, E; Shelef, A; Sinai, O; Stryjer, R; Weizman, S, 2022
)
0.72
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
thioxanthenesThioxanthene and its substitution derivatives.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (33)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (6.06)18.7374
1990's12 (36.36)18.2507
2000's12 (36.36)29.6817
2010's5 (15.15)24.3611
2020's2 (6.06)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.29

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.29 (24.57)
Research Supply Index3.87 (2.92)
Research Growth Index5.16 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.29)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials9 (23.68%)5.53%
Reviews3 (7.89%)6.00%
Case Studies7 (18.42%)4.05%
Observational0 (0.00%)0.25%
Other19 (50.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]