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oxyphenbutazone and Hypothyroidism

oxyphenbutazone has been researched along with Hypothyroidism in 1 studies

Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"A woman who had taken oxyphenbutazone for 4 years because of back pain presented with goitre and hypothyroidism."3.65Oxyphenbutazone-induced goitre. ( Clark, F; Lane, RJ; McCollum, JK, 1977)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lane, RJ1
Clark, F1
McCollum, JK1

Other Studies

1 other study available for oxyphenbutazone and Hypothyroidism

ArticleYear
Oxyphenbutazone-induced goitre.
    Postgraduate medical journal, 1977, Volume: 53, Issue:616

    Topics: Back Pain; Female; Goiter; Humans; Hypothyroidism; Middle Aged; Oxyphenbutazone

1977