trimethoprim has been researched along with Hypothyroidism in 1 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of a 9-year-old spayed female mixed-breed dog with trimethoprim-sulfadiazine for a prolonged period resulted in clinical signs of hypothyroidism, and results of thyroid gland function tests were indistinguishable from those associated with endogenous hypothyroidism." | 7.70 | Clinical hypothyroidism associated with trimethoprim-sulfadiazine administration in a dog. ( Bunch, SE; Gookin, JL; Trepanier, LA, 1999) |
| "Treatment of a 9-year-old spayed female mixed-breed dog with trimethoprim-sulfadiazine for a prolonged period resulted in clinical signs of hypothyroidism, and results of thyroid gland function tests were indistinguishable from those associated with endogenous hypothyroidism." | 3.70 | Clinical hypothyroidism associated with trimethoprim-sulfadiazine administration in a dog. ( Bunch, SE; Gookin, JL; Trepanier, LA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gookin, JL | 1 |
| Trepanier, LA | 1 |
| Bunch, SE | 1 |
1 other study available for trimethoprim and Hypothyroidism
| Article | Year |
|---|---|
Clinical hypothyroidism associated with trimethoprim-sulfadiazine administration in a dog.
Topics: Animals; Anti-Infective Agents, Urinary; Dog Diseases; Dogs; Drug Combinations; Female; Hypothyroidi | 1999 |