lactic acid has been researched along with Hypothyroidism in 15 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 7.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| " The aim of this study was to investigate the effects of hypothyroidism on leucine, mannose, glucose and lactate metabolism in rat cerebellar slices." | 7.79 | Propylthiouracil-induced hypothyroidism during lactation alters leucine and mannose metabolism in rat cerebellar slices. ( da Silveira, CK; de Assis, AM; Farina, M; Longoni, A; Müller, AP; Perry, ML; Souza, DO, 2013) |
| "Metformin-associated lactic acidosis (MALA) carries a high mortality rate." | 3.96 | Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020) |
| " The aim of this study was to investigate the effects of hypothyroidism on leucine, mannose, glucose and lactate metabolism in rat cerebellar slices." | 3.79 | Propylthiouracil-induced hypothyroidism during lactation alters leucine and mannose metabolism in rat cerebellar slices. ( da Silveira, CK; de Assis, AM; Farina, M; Longoni, A; Müller, AP; Perry, ML; Souza, DO, 2013) |
| "Further, neonatal hypothyroidism affected germ cell proliferation with decreased expression of proliferating cell nuclear antigen (PCNA) and Cx43." | 1.46 | Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43. ( Sarkar, D; Singh, SK, 2017) |
| "Treatment with triiodothyronine for 5 or 10 days decreased the sensitivity of glycogen synthesis but increased the sensitivity of lactate formation to insulin." | 1.30 | The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats. ( Bevan, S; Challiss, RA; Dimitriadis, G; Krause, U; Leighton, B; Newsholme, EA; Parry-Billings, M; Piva, T; Tegos, K; Wegener, G, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hiraki, N | 1 |
| Tanaka, TD | 1 |
| Yoshimura, M | 1 |
| Goonoo, MS | 1 |
| Morris, R | 1 |
| Raithatha, A | 1 |
| Creagh, F | 1 |
| Sarkar, D | 1 |
| Singh, SK | 1 |
| Müller, AP | 1 |
| Longoni, A | 1 |
| Farina, M | 1 |
| da Silveira, CK | 1 |
| Souza, DO | 1 |
| Perry, ML | 1 |
| de Assis, AM | 1 |
| Lankhaar, JA | 1 |
| de Vries, WR | 1 |
| Jansen, JA | 1 |
| Zelissen, PM | 1 |
| Backx, FJ | 1 |
| Eynan, M | 1 |
| Knubuvetz, T | 1 |
| Meiri, U | 1 |
| Navon, G | 1 |
| Gerstenblith, G | 1 |
| Bromberg, Z | 1 |
| Hasin, Y | 1 |
| Horowitz, M | 1 |
| Caraccio, N | 1 |
| Natali, A | 1 |
| Sironi, A | 1 |
| Baldi, S | 1 |
| Frascerra, S | 1 |
| Dardano, A | 1 |
| Monzani, F | 1 |
| Ferrannini, E | 1 |
| Storm, H | 1 |
| Van Hardeveld, C | 1 |
| Kassenaar, AA | 1 |
| Almeida, A | 1 |
| González-Buitrago, JM | 1 |
| Bolaños, JP | 1 |
| Medina, JM | 1 |
| Dimitriadis, G | 1 |
| Parry-Billings, M | 1 |
| Bevan, S | 1 |
| Leighton, B | 1 |
| Krause, U | 1 |
| Piva, T | 1 |
| Tegos, K | 1 |
| Challiss, RA | 1 |
| Wegener, G | 1 |
| Newsholme, EA | 1 |
| Kneer, N | 1 |
| Lardy, H | 1 |
| Müller, MJ | 1 |
| Seitz, HJ | 1 |
| Dudley, GA | 1 |
| Tullson, PC | 1 |
| Terjung, RL | 1 |
| Everts, ME | 1 |
| Clausen, T | 1 |
| Heimberg, M | 1 |
| Olubadewo, JO | 1 |
| Wilcox, HG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966] | 50 participants (Anticipated) | Observational | 2021-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lactic acid and Hypothyroidism
| Article | Year |
|---|---|
Impact of overt and subclinical hypothyroidism on exercise tolerance: a systematic review.
Topics: Blood Flow Velocity; Blood Pressure; Echocardiography; Electrocardiography; Exercise Tolerance; Hear | 2014 |
Plasma lipoproteins and regulation of hepatic metabolism of fatty acids in altered thyroid states.
Topics: Alanine; Animals; Apolipoproteins; Cholesterol, HDL; Cholesterol, LDL; Fatty Acids; Fatty Acids, Non | 1985 |
1 trial available for lactic acid and Hypothyroidism
| Article | Year |
|---|---|
Muscle metabolism and exercise tolerance in subclinical hypothyroidism: a controlled trial of levothyroxine.
Topics: Adult; Double-Blind Method; Exercise; Fatty Acids, Nonesterified; Female; Follow-Up Studies; Hormone | 2005 |
12 other studies available for lactic acid and Hypothyroidism
| Article | Year |
|---|---|
A Man With Left Ventricular Hypertrophy.
Topics: Adult; Atrophy; Cardiomyopathies; Cerebellar Diseases; Cognitive Dysfunction; Echocardiography; Gluc | 2022 |
Metformin-associated lactic acidosis: reinforcing learning points.
Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes | 2020 |
Neonatal hypothyroidism affects testicular glucose homeostasis through increased oxidative stress in prepubertal mice: effects on GLUT3, GLUT8 and Cx43.
Topics: Age Factors; Animals; Animals, Newborn; Antioxidants; Apoptosis; Cell Proliferation; Connexin 43; Di | 2017 |
Propylthiouracil-induced hypothyroidism during lactation alters leucine and mannose metabolism in rat cerebellar slices.
Topics: Animals; Carbon Dioxide; Cerebellum; Disease Models, Animal; Female; Glucose; Hypothyroidism; Lactat | 2013 |
Heat acclimation-induced elevated glycogen, glycolysis, and low thyroxine improve heart ischemic tolerance.
Topics: Acclimatization; Animals; Carbon Isotopes; Glucose; Glycogen; Glycolysis; Hot Temperature; Hypothyro | 2002 |
The influence of hypothyroidism on the adrenergic stimulation of glycogenolysis in perfused rat liver.
Topics: Animals; Calcium; Glucose-6-Phosphate; Glucosephosphates; Hypothyroidism; Lactates; Lactic Acid; Liv | 1984 |
Fuel utilization by early newborn brain is preserved under congenital hypothyroidism in the rat.
Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Antithyroid Agents; Brain; Congenital Hypothyroidi | 1996 |
The effects of insulin on transport and metabolism of glucose in skeletal muscle from hyperthyroid and hypothyroid rats.
Topics: Animals; Biological Transport, Active; Cortisone; Dinoprostone; Drug Interactions; Glucose; Glycogen | 1997 |
Thyroid hormone and dehydroepiandrosterone permit gluconeogenic hormone responses in hepatocytes.
Topics: Aminooxyacetic Acid; Animals; Calcium; Cyclic AMP; Dehydroepiandrosterone; Glucagon; Gluconeogenesis | 2000 |
Interrelation between thyroid state and the effect of glucagon on gluconeogenesis in perfused rat livers.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Alanine; Aminoisobutyric Acids; An | 1987 |
Influence of mitochondrial content on the sensitivity of respiratory control.
Topics: Adenylate Kinase; AMP Deaminase; Animals; Creatine Kinase; Glycolysis; Hypothyroidism; Lactates; Lac | 1987 |
Effects of thyroid hormones on calcium contents and 45Ca exchange in rat skeletal muscle.
Topics: Animals; Calcium; Calcium Radioisotopes; Dantrolene; Female; Gallopamil; Hyperthyroidism; Hypothyroi | 1986 |