Page last updated: 2024-08-23

fomesafen and Hypothyroidism

fomesafen has been researched along with Hypothyroidism in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	45 (88.24)	18.7374
1990's	2 (3.92)	18.2507
2000's	1 (1.96)	29.6817
2010's	2 (3.92)	24.3611
2020's	1 (1.96)	2.80

Authors

Authors	Studies
Lee, MY; Maahs, DM	1
Castelán, F; Corona-Quintanilla, DL; Cuevas-Romero, E; López-Juárez, R; Martínez-Gómez, M; Rodríguez-Castelán, J; Sánchez-García, O	1
Dong, Y; Hu, X; Jesse, FF; Li, W; Rao, E; Shan, Z; Takahashi, E; Teng, W; Teng, X; Wang, R; Zheng, H	1
FLEISCHMANN, W; GANTT, WH	1
SIGROTH, K	1
LAWSON, JD	2
BOWERS, CY; GORDON, DL; SEGALOFF, A	1
BINSWANGER, J; STUDER, H; WYSS, F	1
ISAACS, R	1
BLAIR, JH; NARTOWICZ, GR; SIMPSON, GM	1
HALES, I; QUIGLEY, M	1
HIRST, DV	1
BEARDWOOD, DM; SCHUMACHER, LR	1
GEPPERT, LJ; UMLAUF, HJ; WALL, RL	1
MARTINEZ, A; VULPE, M	1
DUC, M; DUC, ML; HARTEMANN, P; KISSEL, P	1
NEWMAN, MK	1
CANLORBE, P; CHEFNEUX, A	1
DOE, RP; NUTTALL, FQ	1
CAVALCA, GG; GUARALDI, GP	1
LEMMON, GB	1
DANOWSKI, TS; MOSES, C	1
FEJER, A; KUN, M	1
BECKER, DV; FURTH, ED; RIVES, KL	1
DURKALEC, J	1
Bhagat, CI; Bhagat, MC; Chew, GT; Cussons, AJ; Dhaliwal, SS; Lim, EM; Shiels, L; Stuckey, BG; Walsh, JP; Ward, LC	1
HAGEDOORN, A	1
Glennon, JA; Kaufman, RP; Reinfrank, RF; Wetstone, HJ	1
Doehne, EF; Edens, CJ; Prange, AJ; Treadway, CR; Whybrow, PC	1
Bantle, JP; Bingham, C; Dillmann, WH; Oppenheimer, JH; Runger, GC	1
Ivanova, ES; Tereshchenko, IV; Tsepelev, VV	1
Avramides, A; Dagilas, A; Delaroudis, S; Goulis, DG; Maltas, B; Tsimpiris, N; Tzoiti, M	1
Bednár, J; Nĕmec, J; Vána, S	1
Croxson, MS; Ibbertson, HK	1
Fundarò, A; Molinengo, L; Orsetti, M	1
Muller, H; Sparkes, RS; Valente, M	1
Adams, PM; Anthony, A; Gerrity, L; Palnitkar, M; Shanklin, DR; Stein, SA	1
Goto, I; Kira, J; Kobayashi, T; Kuga, T; Ohyagi, Y	1
D'Athis, P; Dumas, R; Giroud, M; Nivelon, JL; Tenenbaum, D	1
Korn, JH	1
Baufeld, W; Hendrik, A; Knoke, M; Männchen, E; Meng, S; Meng, W	1
Chesters, MI; Crooks, J; Flemming, CJ; Hedley, AJ; Michie, W	1
Korn, R; Krug, JP; Messer, J; Sacrez, R; Vors, J; Willard, D	1
Di Lauro, L; Federico, F; Genco, S; Masi, G; Puca, FM; Specchio, LM	1
Davenport, JW; Dorcey, TP	1
Barker, DJ; Mucklow, JC	1
Stopczyk, K	1
Emrich, D; Marongiu, F	1
Fankhauser, S; Morell, B; Reubi, F	1

Trials

1 trial(s) available for fomesafen and Hypothyroidism

Article	Year
Combined thyroxine/liothyronine treatment does not improve well-being, quality of life, or cognitive function compared to thyroxine alone: a randomized controlled trial in patients with primary hypothyroidism. The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:10 Topics: Adult; Blood Pressure; Cognition; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypothyroidism; Male; Middle Aged; Patient Compliance; Patient Satisfaction; Quality of Life; Reflex; Thyroxine; Triiodothyronine	2003

Article

Year

Combined thyroxine/liothyronine treatment does not improve well-being, quality of life, or cognitive function compared to thyroxine alone: a randomized controlled trial in patients with primary hypothyroidism.

The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:10

Topics: Adult; Blood Pressure; Cognition; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypothyroidism; Male; Middle Aged; Patient Compliance; Patient Satisfaction; Quality of Life; Reflex; Thyroxine; Triiodothyronine

2003

Other Studies

50 other study(ies) available for fomesafen and Hypothyroidism

Article	Year
50 Years Ago in TheJournal ofPediatrics: The Achilles Reflex Time in Thyroid Disorders. The Journal of pediatrics, 2020, Volume: 217 Topics: Achilles Tendon; Child; Endocrine System Diseases; Epinephrine; Exercise; Goiter, Nodular; History, 20th Century; History, 21st Century; Humans; Hyperthyroidism; Hypothyroidism; Insulin; Pediatrics; Reflex; Thyroid Diseases; Thyrotropin; Thyroxine; Triiodothyronine	2020
Hypothyroidism impairs somatovisceral reflexes involved in micturition of female rabbits. Neurourology and urodynamics, 2018, Volume: 37, Issue:8 Topics: Animals; Antithyroid Agents; Electromyography; Female; Hypothyroidism; Methimazole; Pelvic Floor; Pressure; Rabbits; Reflex; Urethra; Urinary Bladder; Urination; Urodynamics	2018
Perinatal Iron Deficiency-Induced Hypothyroxinemia Impairs Early Brain Development Regardless of Normal Iron Levels in the Neonatal Brain. Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:7 Topics: Anemia, Iron-Deficiency; Animals; Animals, Newborn; Behavior, Animal; Brain; Cerebral Cortex; Disease Models, Animal; Female; Hippocampus; Hypothyroidism; Iodide Peroxidase; Iron; Iron Deficiencies; Liver; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Rats; Reflex; RNA, Messenger; Spectrophotometry, Atomic; Thyroxine; Transcriptome	2016
Effect of thyroid therapy on the conditional reflex function in hypothyroidism. The American journal of psychiatry, 1948, Volume: 104, Issue:11 Topics: Humans; Hypothyroidism; Reflex; Thyroid Gland	1948
Reflex vasodilatation of the fingers in the study of peripheral vascular disorders with special reference to diabetes mellitus. Acta medica Scandinavica. Supplementum, 1957, Volume: 325 Topics: Diabetes Complications; Diabetes Mellitus; Fingers; Humans; Hyperthyroidism; Hypothyroidism; Peripheral Vascular Diseases; Reflex; Vascular Diseases; Vasodilation	1957
The free Achilles reflex in hypothyroidism and hyperthyroidism. The New England journal of medicine, 1958, Oct-16, Volume: 259, Issue:16 Topics: Heel; Hyperthyroidism; Hypothyroidism; Reflex	1958
The myxedema reflex in infants and children with hypothyroidism. The Journal of pediatrics, 1959, Volume: 54, Issue:1 Topics: Child; Humans; Hypothyroidism; Infant; Myxedema; Reflex	1959
The free Achilles reflex as an aid in the diagnosis of thyroid dysfunction. United States Armed Forces medical journal, 1959, Volume: 10, Issue:1 Topics: Humans; Hyperthyroidism; Hypothyroidism; Reflex; Reflex, Stretch; Thyroid Diseases	1959
[The expiration of the tendon reflex in functional disorders of the thyroid gland]. Helvetica medica acta, 1961, Volume: 28 Topics: Hypothyroidism; Reflex; Reflex, Stretch; Tendons	1961
The yawning reflex in hypothyroidism. The Illinois medical journal, 1963, Volume: 123 Topics: Humans; Hypothyroidism; Nervous System Physiological Phenomena; Reflex; Yawning	1963
Diagnostic limitations of Achilles tendon reflex in thyroid disease. New York state journal of medicine, 1963, Apr-15, Volume: 63 Topics: Achilles Tendon; Humans; Hypothyroidism; Reflex; Reflex, Abnormal; Reflex, Stretch; Schizophrenia; Thyroid Diseases	1963
ACHILLES TENDON REFLEX IN THE DIAGNOSIS OF THYROID DISEASE. The Medical journal of Australia, 1963, Oct-12, Volume: 2 Topics: Achilles Tendon; Diagnosis; Equipment and Supplies; Humans; Hyperthyroidism; Hypothyroidism; Reflex; Reflex, Stretch	1963
REFINEMENTS IN TECHNIQUE AND INTERPRETATION OF MUSCLE CONTRACTION TIME (MCT) USED AS AN OFFICE TEST OF THYROID FUNCTION. American journal of obstetrics and gynecology, 1963, Sep-01, Volume: 87 Topics: Achilles Tendon; Female; Humans; Hyperthyroidism; Hypothyroidism; Magnetic Phenomena; Magnetics; Muscle Contraction; Pregnancy; Pregnancy Complications; Reflex; Thyroid Function Tests	1963
DELAY OF THE ACHILLES REFLEX IN DIABETES MELLITUS. The American journal of the medical sciences, 1964, Volume: 247 Topics: Diabetes Mellitus; Diabetic Neuropathies; Humans; Hypothyroidism; Reflex; Tendons	1964
MUSCLE REFLEX PATTERNS IN INFANCY AND CHILDHOOD. NORMAL PATTERNS AND PATTERNS IN THYROID DISORDERS, CEREBRAL PALSY, AND MENINGOPATHIES. The Journal of pediatrics, 1964, Volume: 64 Topics: Cerebral Palsy; Child; Clinical Laboratory Techniques; Down Syndrome; Electrocardiography; Electrophysiology; Humans; Hyperthyroidism; Hypothyroidism; Infant; Infant, Newborn; Meningitis; Physiology; Reflex; Reflex, Abnormal; Triiodothyronine; Vitamin B 12	1964
RAPID ESTIMATION OF THYROID FUNCTION BY PHOTOMOTOGRAPHY. Canadian Medical Association journal, 1964, Jul-18, Volume: 91 Topics: Achilles Tendon; Biomedical Research; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Iodine Isotopes; Reflex; Reflex, Stretch; Thyroid Function Tests	1964
[THE ACHILLES REFLEXOGRAM IN THYROID DISORDERS AND IN ELECTROLYTE METABOLISM DISORDERS]. La Presse medicale, 1964, Sep-19, Volume: 72 Topics: Achilles Tendon; Adrenal Gland Diseases; Diabetes Mellitus; Electrolytes; Emaciation; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Liver Cirrhosis; Reflex; Thyroid Function Tests; Water-Electrolyte Balance	1964
WEAKNESS, ATONIA AND WASTING OF THE MUSCLES IN THE AGED: DIAGNOSTIC METHODS. Journal of the American Geriatrics Society, 1964, Volume: 12 Topics: Cachexia; Diabetic Neuropathies; Diagnosis; Electromyography; Geriatrics; Hemiplegia; Humans; Hyperthyroidism; Hypothyroidism; Muscular Atrophy; Myotonia; Neurons; Reflex	1964
[PRACTICAL VALUE OF THE ACHILLES REFLEXOGRAM FOR THE DIAGNOSIS AND THERAPEUTIC EQUILIBRATION OF HYPOTHYROIDISM IN INFANTS AND CHILDREN]. Les Cahiers du College de medecine des hopitaux de Paris, 1964, Oct-15, Volume: 5 Topics: Achilles Tendon; Child; Diagnosis; Humans; Hypothyroidism; Infant; Reflex; Reflex, Stretch	1964
THE ACHILLES REFLEX IN THYROID DISORDERS; A CRITICAL EVALUATION. Annals of internal medicine, 1964, Volume: 61 Topics: Achilles Tendon; Adrenocorticotropic Hormone; Aging; Anemia; Anemia, Pernicious; Aspirin; Cold Temperature; Cortisone; Dextroamphetamine; Epinephrine; Guanethidine; Hot Temperature; Humans; Hyperthyroidism; Hypogonadism; Hypothyroidism; Leg; Myotonic Dystrophy; Myxedema; Pharmacology; Reflex; Reflex, Stretch; Reserpine	1964
[EVALUATION OF THYROID FUNCTION BY MEANS OF THE ACHILLES REFLEXOGRAPHIC TEST IN SOME NEUROPSYCHIATRIC DISORDERS]. Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1964, Sep-30, Volume: 88 Topics: Achilles Tendon; Humans; Hyperthyroidism; Hypothyroidism; Mental Disorders; Nervous System Diseases; Physiology; Reflex; Thyroid Gland	1964
HYPOTHYROIDISM AND ALLERGY: CONFUSION IN DIAGNOSIS. Missouri medicine, 1965, Volume: 62 Topics: Confusion; Conjunctivitis; Diagnosis, Differential; Humans; Hypersensitivity; Hypothyroidism; Reflex; Reflex, Stretch; Rhinitis; Rhinitis, Allergic, Seasonal; Tendons	1965
THYROID INDICES DURING REPLACEMENT WITH DESICCATED THYROID AND PROLOID. Metabolism: clinical and experimental, 1965, Volume: 14 Topics: Cholesterol; Drug Therapy; Fatty Acids; Humans; Hypothyroidism; Lipids; Lipoproteins; Myxedema; Pharmacology; Reflex; Reflex, Stretch; Tendons; Thyroid Function Tests; Thyroid Hormones; Thyroxine; Triiodothyronine	1965
[MEASURING THE SEMIRELAXATION TIME OF THE ACHILLES TENDON REFLEX]. Orvosi hetilap, 1965, Mar-21, Volume: 106 Topics: Achilles Tendon; Humans; Hyperthyroidism; Hypothyroidism; Myxedema; Physiology; Reflex; Reflex, Stretch	1965
LIMITATIONS OF THE ANKLE JERK TEST: INTERCOMPARISON WITH OTHER TESTS OF THYROID FUNCTION. Annals of internal medicine, 1965, Volume: 62 Topics: Achilles Tendon; Ankle; Diagnosis; Humans; Hyperthyroidism; Hypothyroidism; Iodine Isotopes; Muscle Contraction; Reflex; Reflex, Stretch; Thyroid Function Tests	1965
[GRAPHIC RECORDING OF MUSCULAR CONTRACTIONS (JUMP REFLEX) IN THYROID HYPOFUNCTION AND HYPERFUNCTION]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1964, Nov-23, Volume: 19 Topics: Humans; Hyperthyroidism; Hypothyroidism; Muscle Contraction; Reflex	1964
[Idiopathic hypothyroidism, cataract and low tendon reflexes]. Nederlands tijdschrift voor geneeskunde, 1949, Dec-17, Volume: 93, Issue:51 Topics: Cataract; Humans; Hypothyroidism; Parathyroid Glands; Paratyphoid Fever; Reflex; Reflex, Stretch; Tendons	1949
Observations of the Achilles reflex test. JAMA, 1967, Jan-02, Volume: 199, Issue:1 Topics: Achilles Tendon; Adolescent; Adult; Aged; Child; Child, Preschool; Diabetes Mellitus; Humans; Hyperthyroidism; Hypothyroidism; Middle Aged; Reflex; Thyroid Function Tests	1967
The Achilles heel of the ankle jerk. JAMA, 1967, Jan-02, Volume: 199, Issue:1 Topics: Achilles Tendon; Humans; Hypothyroidism; Reflex	1967
Myxedema psychosis: clinical and biochemical changes during recovery. Journal of psychiatric research, 1967, Volume: 5, Issue:4 Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adult; Ankle; Catecholamines; Epinephrine; Female; Humans; Hypothyroidism; Mandelic Acids; Myxedema; Norepinephrine; Psychological Tests; Psychotic Disorders; Reaction Time; Reflex; Thyroid Hormones	1967
Common clinical indices of thyroid hormone action: relationships to serum free 3,5,3'-triiodothyronine concentration and estimated nuclear occupancy. The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:2 Topics: Adult; Cell Nucleus; Cholesterol; Creatine Kinase; Female; Heart Rate; Humans; Hyperthyroidism; Hypothyroidism; Kidney; Kinetics; Liver; Male; Middle Aged; Receptors, Cell Surface; Reflex; Thyroid Hormones; Triiodothyronine	1980
[Subclinical hypothyroidism in patients with ischemic heart disease]. Kardiologiia, 1993, Volume: 33, Issue:11 Topics: Achilles Tendon; Aged; Amiodarone; Angina, Unstable; Arrhythmias, Cardiac; Euthyroid Sick Syndromes; Humans; Hypertension; Hypothyroidism; Middle Aged; Myocardial Ischemia; Reflex	1993
Stapedial reflex: a biological index found to be abnormal in clinical and subclinical hypothyroidism. Thyroid : official journal of the American Thyroid Association, 1998, Volume: 8, Issue:7 Topics: Acoustic Impedance Tests; Adult; Audiometry; Case-Control Studies; Female; Humans; Hypothyroidism; Male; Middle Aged; Physical Examination; Predictive Value of Tests; Reflex; Stapedius	1998
Delayed response of ankle jerk time changes in decreasing thyroid function in comparison with the serum cholesterol changes. Endokrinologie, 1975, Volume: 65, Issue:2 Topics: Ankle; Cholesterol; Humans; Hypothyroidism; Reflex; Thyroid Function Tests	1975
Low serum triiodothyronine (T3) and hypothyroidism in anorexia nervosa. The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:1 Topics: Achilles Tendon; Adolescent; Adult; Anorexia Nervosa; Body Weight; Brain Neoplasms; Female; Humans; Hypothalamus; Hypothyroidism; Iodides; Male; Pituitary Neoplasms; Reflex; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Time Factors; Triiodothyronine	1977
The "grasping reflex" in rats with altered thyroid activity. Bollettino della Societa italiana di biologia sperimentale, 1979, Apr-30, Volume: 55, Issue:8 Topics: Animals; Foot; Forelimb; Hyperthyroidism; Hypothyroidism; Male; Methimazole; Rats; Reflex; Thyroxine	1979
Ring 11 chromosome (46,xx,r11(p15q25)). Human genetics, 1977, May-10, Volume: 36, Issue:3 Topics: Child; Child Behavior Disorders; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 6-12 and X; Electroencephalography; Female; Growth Disorders; Humans; Hypothyroidism; Intellectual Disability; Karyotyping; Reflex	1977
Evaluation and characterization of the hypothyroid hyt/hyt mouse. I: Somatic and behavioral studies. Neuroendocrinology, 1989, Volume: 49, Issue:2 Topics: Animals; Avoidance Learning; Behavior, Animal; Crosses, Genetic; Escape Reaction; Female; Fetus; Hypothyroidism; Male; Mice; Mice, Mutant Strains; Motor Activity; Reflex; Swimming; Thyroxine	1989
[A case of syncope attack due to vagal reflex of rest angina]. Rinsho shinkeigaku = Clinical neurology, 1988, Volume: 28, Issue:8 Topics: Adult; Angina Pectoris; Coronary Vasospasm; Female; Humans; Hypothyroidism; Reflex; Syncope; Vagus Nerve	1988
[Neurophysiological study of peripheral nerves in newborn infants with congenital hypothyroidism. Value in the surveillance of replacement therapy]. Archives francaises de pediatrie, 1988, Volume: 45, Issue:3 Topics: Congenital Hypothyroidism; Electrophysiology; Female; Humans; Hyperthyroidism; Hypothyroidism; Infant, Newborn; Male; Neural Conduction; Peripheral Nerves; Prospective Studies; Reflex; Sural Nerve	1988
The effect of thyroid hormone and an antithyroid drug on the startle response of the rat. Journal of psychosomatic research, 1966, Volume: 9, Issue:4 Topics: Animals; Antithyroid Agents; Heart Rate; Hyperthyroidism; Hypothyroidism; Rats; Reflex; Reflex, Startle; Triiodothyronine	1966
[Significance and reliability of various methods in thyroid gland diagnostics]. Das Deutsche Gesundheitswesen, 1969, Oct-23, Volume: 24, Issue:43 Topics: Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Lipids; Methods; Radioisotope Dilution Technique; Reflex; Thyroid Function Tests; Vital Capacity	1969
Surgical treatment of thyrotoxicosis. British medical journal, 1970, Feb-28, Volume: 1, Issue:5695 Topics: Diet; Electrocardiography; Environment; Female; Humans; Hyperthyroidism; Hypothyroidism; Iodine Isotopes; Male; Reflex; Retrospective Studies; Thyroid Function Tests; Thyroidectomy; Thyroxine	1970
[Primary anterior pituitary dysgenesis]. La Nouvelle presse medicale, 1972, Sep-30, Volume: 1, Issue:34 Topics: Adrenal Insufficiency; Cryptorchidism; Cyanosis; Electrocardiography; Estriol; Female; Humans; Hypertrichosis; Hypoglycemia; Hypothyroidism; Infant, Newborn; Male; Maternal-Fetal Exchange; Pituitary Gland; Pregnancy; Pregnancy, Prolonged; Reflex; Water-Electrolyte Balance	1972
[Vestibulo-oculomotor reflexes in the course of dysmetabolic coma (author's transl)]. Rivista di patologia nervosa e mentale, 1974, Volume: 95, Issue:5 Topics: Coma; Hepatic Encephalopathy; Humans; Hypothyroidism; Insulin Coma; Oculomotor Nerve; Reflex; Uremia; Vestibular Function Tests; Vestibular Nerve	1974
Hypothyroidism: learning deficit induced in rats by early exposure to thiouracil. Hormones and behavior, 1972, Volume: 3, Issue:2 Topics: Age Factors; Animals; Animals, Newborn; Avoidance Learning; Body Weight; Conditioning, Operant; Critical Period, Psychological; Discrimination Learning; Dose-Response Relationship, Drug; Extinction, Psychological; Female; Fetus; Gestational Age; Humans; Hypothyroidism; Learning Disabilities; Male; Maternal-Fetal Exchange; Pregnancy; Rats; Reflex; Reversal Learning; Space Perception; Thiouracil	1972
Ankle reflex timing as a screening procedure for the detection of hypothyroidism. British journal of preventive & social medicine, 1970, Volume: 24, Issue:1 Topics: Ankle; Humans; Hyperthyroidism; Hypothyroidism; Iodine Isotopes; Reflex; Thyroxine; Time Factors	1970
Reflexograph in evaluation of thyroid function in healthy children and in children with hormonal disturbances. Polish medical science and history bulletin, 1971, Volume: 14, Issue:2 Topics: Child; Humans; Hyperthyroidism; Hypothyroidism; Reflex; Thyroid Diseases; Thyroid Function Tests	1971
[Registration of the Achilles tendon reflex as a diagnostic aid in thyroid diseases]. Deutsche medizinische Wochenschrift (1946), 1966, Jan-21, Volume: 91, Issue:3 Topics: Achilles Tendon; Humans; Hyperthyroidism; Hypothyroidism; Iodine Radioisotopes; Reflex; Thyroid Function Tests	1966
[Changes in Achilles tendon reflex time in patients with renal insufficiency]. Deutsche medizinische Wochenschrift (1946), 1966, Apr-22, Volume: 91, Issue:16 Topics: Achilles Tendon; Acute Kidney Injury; Humans; Hyperkalemia; Hypothyroidism; Ion Exchange Resins; Kidney Diseases; Kidney Failure, Chronic; Kidneys, Artificial; Peritoneal Dialysis; Reflex; Water-Electrolyte Balance	1966