flunitrazepam has been researched along with Hypothyroidism in 2 studies
Flunitrazepam: A benzodiazepine with pharmacologic actions similar to those of DIAZEPAM that can cause ANTEROGRADE AMNESIA. Some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. The United States Government has banned the importation of this drug.
flunitrazepam : A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In rats rendered hyperthyroid by chronic treatment with L-triiodothyronine (T3) hormone there was a 21 and 27% decrease, respectively, in the number of binding sites for [3H]flunitrazepam ([3H]FNZ) and [3H]ethyl-beta-carboline-3-carboxylate ([3H]beta-CCE) without changes in affinity for the two ligands." | 3.67 | Benzodiazepine receptor and thyroid hormones: in vivo and in vitro modulation. ( De Robertis, E; Medina, JH, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ortiz-Butron, R | 1 |
| Pacheco-Rosado, J | 1 |
| Hernández-Garcia, A | 1 |
| Briones-Velasco, M | 1 |
| Rocha, L | 1 |
| Medina, JH | 1 |
| De Robertis, E | 1 |
2 other studies available for flunitrazepam and Hypothyroidism
| Article | Year |
|---|---|
Mild thyroid hormones deficiency modifies benzodiazepine and mu-opioid receptor binding in rats.
Topics: Animals; Antithyroid Agents; Autoradiography; Binding, Competitive; Brain; Enkephalin, Ala(2)-MePhe( | 2003 |
Benzodiazepine receptor and thyroid hormones: in vivo and in vitro modulation.
Topics: Animals; Cerebral Cortex; Female; Flunitrazepam; Hyperthyroidism; Hypothyroidism; Male; Rats; Recept | 1985 |