Page last updated: 2024-10-20

pyruvic acid and Hypothyroidism

pyruvic acid has been researched along with Hypothyroidism in 11 studies

Pyruvic Acid: An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
pyruvic acid : A 2-oxo monocarboxylic acid that is the 2-keto derivative of propionic acid. It is a metabolite obtained during glycolysis.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Isolated hepatocytes from hypothyroid, euthyroid and hyperthyroid rats have been employed to investigate the relative importance of reducing-equivalent shuttles for the transfer of hydrogen between cytoplasm and mitochondria during simultaneous ureogenesis and gluconeogenesis."3.68Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status. ( Berry, MN; Gregory, RB; Phillips, JW, 1992)
"Glucose metabolism was studied as evidenced by the sugar and pyruvic acid levels in blood and glycogen and pyruvic acid content of tissues in euthyroid, hypothyroid and hyperthyroid rats by giving insulin."3.67Glucose metabolism in insulin administered euthyroid, hypothyroid and hyperthyroid rats. ( Chandra, AK; Mukherjee, AK, 1985)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's4 (36.36)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Hiraki, N1
Tanaka, TD1
Yoshimura, M1
Venditti, P1
Napolitano, G1
Barone, D1
Coppola, I1
Di Meo, S1
SAKUNO, T1
Katyare, SS1
Rajan, RR1
Müller, MJ1
Seitz, HJ1
Pehowich, DJ1
Gregory, RB3
Phillips, JW2
Henly, DC1
Berry, MN3
Kneer, N1
Lardy, H1
Chandra, AK1
Mukherjee, AK1

Other Studies

11 other studies available for pyruvic acid and Hypothyroidism

ArticleYear
A Man With Left Ventricular Hypertrophy.
    JAMA cardiology, 2022, 02-01, Volume: 7, Issue:2

    Topics: Adult; Atrophy; Cardiomyopathies; Cerebellar Diseases; Cognitive Dysfunction; Echocardiography; Gluc

2022
Effect of thyroid state on enzymatic and non-enzymatic processes in H2O2 removal by liver mitochondria of male rats.
    Molecular and cellular endocrinology, 2015, Mar-05, Volume: 403

    Topics: Animals; Cell Fractionation; Cytochromes c; Glutathione Peroxidase; Glutathione Reductase; Hepatocyt

2015
[STUDIES ON THE METABOLISM OF PYRUVIC AND ALPHA-KETOGLUTARIC ACIDS. 3. OBSERVATIONS ON THE CHANGES OF THE BLOOD PYRUVIC ACID LEVEL FOLLOWING THE ADMINISTRATION OF FRUCTOSE OR GLUCOSE IN THYROID DISEASES].
    Naika hokan. Japanese archives of internal medicine, 1963, Volume: 10

    Topics: Blood Chemical Analysis; Fructose; Glucose; Hyperthyroidism; Hypothyroidism; Injections, Intravenous

1963
Influence of thyroid hormone treatment on the respiratory activity of cerebral mitochondria from hypothyroid rats. A critical re-assessment.
    Experimental neurology, 2005, Volume: 195, Issue:2

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Cytochromes; Dose-Response Relationship, Drug; Hypothyro

2005
Starvation-induced changes of hepatic glucose metabolism in hypo- and hyperthyroid rats in vivo.
    The Journal of nutrition, 1981, Volume: 111, Issue:8

    Topics: Animals; Citrates; Citric Acid; Cyclic AMP; Energy Metabolism; Gluconeogenesis; Hyperthyroidism; Hyp

1981
Hypothyroid state and membrane fatty acid composition influence cardiac mitochondrial pyruvate oxidation.
    Biochimica et biophysica acta, 1995, May-04, Volume: 1235, Issue:2

    Topics: Animals; Delta-5 Fatty Acid Desaturase; Dietary Fats; Fatty Acid Desaturases; Fatty Acids; Fatty Aci

1995
Effects of thyroid status on glucose cycling by isolated rat hepatocytes.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Fructosediphosphates; Fructosephosphates; Glucose; Glucos

1996
Thyroid hormone and dehydroepiandrosterone permit gluconeogenic hormone responses in hepatocytes.
    Archives of biochemistry and biophysics, 2000, Mar-01, Volume: 375, Issue:1

    Topics: Aminooxyacetic Acid; Animals; Calcium; Cyclic AMP; Dehydroepiandrosterone; Glucagon; Gluconeogenesis

2000
Reducing-equivalent transfer to the mitochondria during gluconeogenesis and ureogenesis in hepatocytes from rats of different thyroid status.
    Biochimica et biophysica acta, 1992, Oct-06, Volume: 1137, Issue:1

    Topics: Alanine; Animals; Aspartic Acid; Biological Transport; Cells, Cultured; Cytoplasm; Gluconeogenesis;

1992
Stimulation by thyroid hormone of coupled respiration and of respiration apparently not coupled to the synthesis of ATP in rat hepatocytes.
    The Journal of biological chemistry, 1992, May-05, Volume: 267, Issue:13

    Topics: Adenosine Triphosphate; Animals; Atractyloside; Energy Metabolism; Gluconeogenesis; Hyperthyroidism;

1992
Glucose metabolism in insulin administered euthyroid, hypothyroid and hyperthyroid rats.
    Endocrinologia japonica, 1985, Volume: 32, Issue:4

    Topics: Animals; Blood Glucose; Female; Glucose; Glycogen; Hyperthyroidism; Hypothyroidism; Insulin; Kidney;

1985