antipyrine has been researched along with Hypothyroidism in 7 studies
Antipyrine: An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
antipyrine : A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The salivary kinetics and rates of metabolite formation of antipyrine were studied in 6 hyperthyroid and 6 hypothyroid out-patients on 2 occasions, on admission and when T3 and T4 levels had returned to normal after treatment with carbimazole (hyperthyroidism) or l-thyroxine (hyperthyroidism)." | 3.67 | Influence of mild thyroid dysfunction on antipyrine clearance and metabolite formation in man. ( Breimer, DD; Doodeman, PJ; Teunissen, MW; van der Veen, EA, 1984) |
| "The metabolism of phenytoin was studied in 9 hyperthyroid and 7 hypothyroid patients before and after treatment with either antithyroid drugs or 1-thyroxine." | 3.66 | Unaltered metabolism of phenytoin in thyroid disorders. ( Kampmann, JP; Lumholtz, BI; Mølholm Hansen, J; Siersbaek-Nielsen, K; Skovsted, L, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teunissen, MW | 1 |
| van der Veen, EA | 1 |
| Doodeman, PJ | 1 |
| Breimer, DD | 1 |
| Mølholm Hansen, J | 1 |
| Skovsted, L | 1 |
| Kampmann, JP | 1 |
| Lumholtz, BI | 1 |
| Siersbaek-Nielsen, K | 1 |
| Vesell, ES | 1 |
| Shapiro, JR | 1 |
| Passananti, T | 1 |
| Jorgensen, H | 1 |
| Shively, CA | 1 |
| Saenger, P | 1 |
| Rifkind, AB | 1 |
| New, MI | 1 |
| Gugler, R | 2 |
| Eichelbaum, M | 2 |
| Schneider-Deters, C | 1 |
| Bodem, G | 2 |
| Dengler, HJ | 2 |
| Schneider-Deters, D | 1 |
| Wilkinson, R | 1 |
| Anderson, M | 1 |
| Smart, GA | 1 |
7 other studies available for antipyrine and Hypothyroidism
| Article | Year |
|---|---|
Influence of mild thyroid dysfunction on antipyrine clearance and metabolite formation in man.
Topics: Adult; Aged; Antipyrine; Biotransformation; Female; Half-Life; Humans; Hyperthyroidism; Hypothyroidi | 1984 |
Unaltered metabolism of phenytoin in thyroid disorders.
Topics: Adult; Aged; Antipyrine; Female; Half-Life; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Ag | 1978 |
Altered plasma half-lives of antipyrine, propylthiouracil, and methimazole in thyroid dysfunction.
Topics: Adult; Aged; Antipyrine; Biotransformation; Female; Half-Life; Humans; Hyperthyroidism; Hypothyroidi | 1975 |
Changes in drug metabolism in children with thyroid disorders.
Topics: Adolescent; Antipyrine; Child; Child, Preschool; Half-Life; Humans; Hyperthyroidism; Hypothyroidism; | 1976 |
[Influence of thyroid function on human drug metabolism].
Topics: Antipyrine; Humans; Hyperthyroidism; Hypothyroidism; Pharmaceutical Preparations; Thyroid Gland | 1973 |
Influence of thyroid status on plasma half-life of antipyrine in man.
Topics: Administration, Oral; Adult; Aged; Antipyrine; Biotransformation; Cholesterol; Female; Half-Life; He | 1974 |
Growth-hormone deficiency in iatrogenic hypothyroidism.
Topics: Adult; Antipyrine; Body Height; Caffeine; Dwarfism, Pituitary; Growth Hormone; Humans; Hypothyroidis | 1972 |