Page last updated: 2024-08-18

pyrroles and Hypothyroidism

pyrroles has been researched along with Hypothyroidism in 71 studies

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (1.41)	18.2507
2000's	24 (33.80)	29.6817
2010's	45 (63.38)	24.3611
2020's	1 (1.41)	2.80

Authors

Authors	Studies
Blackwood, L; Harper, A; Mason, S	1
Buda-Nowak, A; Dumnicka, P; Herman, RM; Kucharz, J; Kusnierz-Cabala, B; Kuzniewski, M; Zygulska, AL	1
Balkman, CE; Cawley, JR; Hume, KR; Rizzo, VL	1
Banerjee, D; Bhowmick, R; Manir, KS; Roy, C	1
Haq, S; Hershman, JM; Liwanpo, L; Ro, C	1
Bolanča, A; Jakšić, B; Jazvić, M; Krilić, D; Kusić, Z; Kust, D; Murgić, J; Prpić, M	1
Cao, J; Hu, X; Lv, F; Wang, B; Wang, L; Wang, Z; Zhang, J	1
Cserháti, A; Kahán, Z; Maráz, A; Szilágyi, E; Uhercsák, G; Varga, Z	1
Baldazzi, V; Carini, M; Lapini, A; Mazzanti, R; Tassi, R	1
Berk, V; Bozkurt, O; Duran, AO; Duzkopru, Y; Hacıbekiroglu, I; Inanc, M; Kaplan, MA; Karaca, H; Ozaslan, E; Ozkan, M; Ucar, M; Uysal, M	1
Charles, LP; DeAnnuntis, L; Escudier, B; Gore, ME; Hariharan, S; Motzer, RJ; Porta, C; Rini, BI; Yang, L	1
Čaržavec, D; Gaćina, P; Kruljac, I; Kust, D; Ostojić, J; Peternac, AŠ; Prpić, M	1
Lin, Z; Shu, M; Wang, R; Zai, X; Zhang, B	1
Keck, B; Lieb, V; Lüdecke, G; Sikic, D	1
Atzori, F; Baghino, G; Boi, F; Ionta, MT; Mariotti, S; Pani, F; Scartozzi, M; Tanca, L	1
Golčić, M; Petković, M	1
Aubert, RE; Clore, G; Epstein, RS; Herrera, V; Kourlas, H; La-Beck, NM; McLeod, HL; Walko, CM	1
Bex, M; Carmeliet, P; Decallonne, B; Dumez, H; Schöffski, P; Stefan, C; Wolter, P	1
Davis, P; Garfield, DH; Hercbergs, A; Schöffski, P; Wolter, P	1
Porta, C; Szczylik, C	1
Barnabei, A; Corsello, SM; Gasparini, G; Longo, R; Torino, F	2
Knopp, RH; Krieger, EV	1
Kosák, M; Koskuba, J; Kreze, A; Stáhalová, V; Zadrazilová, A	1
Carbonell, CE; Coleman, TA; Davis, CH; Davis, WB; La Vine, DB	1
Díaz-Rubio, E; López-Tarruella, S; Manzano, A; Martin, M; Puente, J	1
Decallonne, B; Op de Beeck, K; Rogiers, A; Schöffski, P; Thijs, M; Wolter, P	1
Hershman, JM; Liwanpo, L	1
Fujita, T; Iiri, T; Makita, N; Miyakawa, M	1
Boyle, H; Fléchon, A; Négrier, S	1
De Miguel Novoa, MP; Díaz Pérez, JÁ; Fuertes Zamorano, N; Molino González, A; Montañez Zorrilla, MC; Rojas-Marcos, PM	1
Hiromatsu, Y; Matsuoka, K; Miyajima, J; Muraishi, K; Sasaki, Y; Sato, S; Suekane, S; Tajiri, Y; Tani, J; Tokubuchi, I; Yamada, K	1
Arihara, Z; Fukazawa, H; Sakurai, K; Yoshida, K	1
Bojic, M; Clodi, M; Haitel, A; Heinzl, H; Kramer, G; Lamm, W; Schmidinger, M; Vogl, UM; Zielinski, CC	1
Baldazzi, V; Carini, M; Lapini, A; Mazzanti, R; Santomaggio, C; Tassi, R	1
Rini, B	1
Berkin, L; Brown, JE; Collinson, FJ; Khan, MM; Selby, PJ; Vasudev, NS	1
Bierer, S; Herrmann, E; Hertle, L; Hoffmeister, I; Köpke, T; Papavassilis, P; Riesenbeck, LM; Thielen, B	1
Cano Megías, M; Carrasco De La Fuente, M; González Albarrán, O; Menacho Román, M; Pérez López, G	1
Ceresoli, GL; Colombo, P; De Sanctis, R; De Vincenzo, F; Gianoncelli, L; Graziotti, P; Lorenzi, E; Perrino, M; Santoro, A; Simonelli, M; Zucali, PA	1
Bjarnason, G; Bukowski, R; Burnett, P; Creel, P; Davis, M; Dawson, N; Feldman, D; George, S; Hershman, J; Kollmannsberger, C; Lechner, T; Potter, A; Raymond, E; Treister, N; Wood, L; Wu, S	1
Bladou, F; Boher, JM; Brunelle, S; Deville, JL; Eymard, JC; Gravis, G; Marcy, M; Narbonne, H; Sabatier, R; Salem, N; Viens, P; Walz, J	1
Fujii, M; Fujisawa, M; Kitajima, K; Maeda, T; Miyake, H; Ohno, Y; Sugimura, K; Takahashi, S; Yoshikawa, T	1
Danser, AH; de Krijger, RR; Eechoute, K; Kappers, MH; Leijten, F; Mathijssen, RH; Sleijfer, S; Smedts, FM; van den Meiracker, AH; van Esch, JH; Visser, TJ	1
Brown, RL	1
Antón-Aparicio, L; Aparicio-Gallego, G; Blanco, M; Figueroa, A; García-Campelo, R; Grande-Pulido, E; Valladares-Ayerbes, M	1
Eisen, T; Escudier, B; Izzedine, H; Mulders, P; Pyle, L; Robert, C; Sternberg, CN; Zbinden, S	1
Czeche, S; Feldt, S; Franzmann, A; Ludwig, WD; Quinzler, R; Schulz, M; Schüssel, K	1
Hanovich, E; Hercbergs, AH; Kovel, S; Sella, A	1
Breaker, K; Clemons, J; Flaig, TW; Gao, D; Garfield, D; Naam, M	1
Bruera, E; Busaidy, NL; Cabanillas, ME; Del Fabbro, E; Dev, R; Rodriguez, EC	1
Funakoshi, T; Shimada, YJ	1
Iiri, T; Makita, N	1
Cording, SA; Newnham, HH; Rando, LP	1
Borbely, A; Mezosi, E; Nagy, EV; Paragh, G; Szabo, J; Varga, E; Varga, Z	1
de Groot, JW; Links, TP; van der Graaf, WT	1
Alexander, EK; Chen, MH; Demetri, GD; Desai, J; Dychter, SS; Frates, MC; George, S; Larsen, PR; Marqusee, E; Morgan, JA; Yassa, L	1
Bukowski, RM; Dreicer, R; Garcia, J; Reddy, S; Rini, BI; Salas, R; Shaheen, P; Tamaskar, I; Wood, L	1
Senior, K	1
Dumez, H; Schöffski, P; Wolter, P	1
Dinolfo, M; Hershman, JM; Mulay, M; Rosen, LS; Sugawara, M; Tomoda, C; Vanvugt, A; Wong, E	1
Davis, PJ; Garfield, DH; Hercbergs, A	1
Feldman, DR; Martorella, AJ; Motzer, RJ; Robbins, RJ	1
Beck-Peccoz, P; Bertuelli, R; Carletto, M; Casali, PG; Coco, P; Fugazzola, L; Mannavola, D; Vannucchi, G	1
Bihan, H; Cohen, R; des Guetz, G; Krivitzky, A; Uzzan, B	1
Berets, O; Bladé, JS; Defuentes, G	1
Davis, P; Garfield, D; Hercbergs, A	1
Calvo, E; Prat, A; Serrano, C; Valverde, C	1
Jagadish, M; Mishra, SK; Raviprakash, V; Telang, AG	1

Reviews

10 review(s) available for pyrroles and Hypothyroidism

Article	Year
[Side effect management of tyrosine kinase inhibitors in urology : Fatigue and hypothyroidism]. Der Urologe. Ausg. A, 2016, Volume: 55, Issue:5 Topics: Anilides; Antineoplastic Agents; Axitinib; Carcinoma, Renal Cell; Disease Progression; Enzyme Inhibitors; Fatigue; Humans; Hypothyroidism; Imidazoles; Indazoles; Indoles; Kidney Neoplasms; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Quality of Life; Sorafenib; Sulfonamides; Sunitinib	2016
Tolerability of first-line therapy for metastatic renal cell carcinoma. Cancer treatment reviews, 2009, Volume: 35, Issue:3 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Blood Coagulation Disorders; Carcinoma, Renal Cell; Cardiovascular Diseases; Clinical Trials, Phase III as Topic; Disease-Free Survival; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hypothyroidism; Indoles; Interferons; Kidney Neoplasms; Multicenter Studies as Topic; Neoplasm Proteins; Pyrroles; Randomized Controlled Trials as Topic; Receptors, Vascular Endothelial Growth Factor; Sirolimus; Sunitinib; Wound Healing	2009
Hypothyroidism related to tyrosine kinase inhibitors: an emerging toxic effect of targeted therapy. Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:4 Topics: Antineoplastic Agents; Benzenesulfonates; Drug Therapy, Combination; Humans; Hypothyroidism; Indoles; Neoplasms; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Risk Assessment; Sorafenib; Sunitinib; Thyroid Function Tests; Treatment Outcome	2009
Sunitinib in metastatic renal cell carcinoma: recommendations for management of noncardiovascular toxicities. The oncologist, 2011, Volume: 16, Issue:5 Topics: Asthenia; Carcinoma, Renal Cell; Diarrhea; Dose-Response Relationship, Drug; Erythema; Exanthema; Fatigue; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Practice Guidelines as Topic; Protein Kinase Inhibitors; Pyrroles; Standard of Care; Sunitinib	2011
Tyrosine kinase inhibitor-induced hypothyroidism: incidence, etiology, and management. Targeted oncology, 2011, Volume: 6, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Humans; Hypothyroidism; Incidence; Indoles; Protein Kinase Inhibitors; Pyrroles; Sunitinib	2011
New insights into molecular mechanisms of sunitinib-associated side effects. Molecular cancer therapeutics, 2011, Volume: 10, Issue:12 Topics: Animals; Antineoplastic Agents; Carcinoma, Renal Cell; Drug-Related Side Effects and Adverse Reactions; Humans; Hypertension; Hypothyroidism; Indoles; Kidney Neoplasms; Models, Biological; Pigmentation Disorders; Pyrroles; Signal Transduction; Sunitinib	2011
Targeted therapies for renal cell carcinoma: review of adverse event management strategies. Journal of the National Cancer Institute, 2012, Jan-18, Volume: 104, Issue:2 Topics: Anorexia; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Cardiovascular System; Drug Eruptions; Europe; Everolimus; Evidence-Based Medicine; Gastrointestinal Tract; Humans; Hypothyroidism; Indazoles; Indoles; Kidney Neoplasms; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Pneumonia; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Sirolimus; Sorafenib; Sulfonamides; Sunitinib; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A; Weight Loss; Wound Healing	2012
Risk of hypothyroidism in patients with cancer treated with sunitinib: a systematic review and meta-analysis. Acta oncologica (Stockholm, Sweden), 2013, Volume: 52, Issue:4 Topics: Algorithms; Antineoplastic Agents; Humans; Hypothyroidism; Incidence; Indoles; Neoplasms; Pyrroles; Randomized Controlled Trials as Topic; Risk; Risk Factors; Sunitinib	2013
Tyrosine kinase inhibitor-induced thyroid disorders: a review and hypothesis. Thyroid : official journal of the American Thyroid Association, 2013, Volume: 23, Issue:2 Topics: Humans; Hypothyroidism; Indoles; Neovascularization, Pathologic; Protein Kinase Inhibitors; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Sunitinib; Thyroid Diseases; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2	2013
[Sunitinib and hypothyroidism]. Annales d'endocrinologie, 2007, Volume: 68, Issue:5 Topics: Angiogenesis Inhibitors; Clinical Trials as Topic; Humans; Hypothyroidism; Indoles; Pyrroles; Sunitinib	2007

Trials

5 trial(s) available for pyrroles and Hypothyroidism

Article	Year
Hypothyroidism as a potential biomarker of efficacy of famitinib, a novel VEGFR-2 inhibitor in metastatic breast cancer. Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:2 Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Female; Follow-Up Studies; Humans; Hypothyroidism; Indoles; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Prognosis; Pyrroles; Survival Rate; Thyrotropin; Vascular Endothelial Growth Factor Receptor-2; Young Adult	2014
The impact of sunitinib-induced hypothyroidism on progression-free survival of metastatic renal cancer patients: a prospective single-center study. Urologic oncology, 2012, Volume: 30, Issue:5 Topics: Aged; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypothyroidism; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib; Thyroid Function Tests; Thyrotropin; Time Factors; Treatment Outcome	2012
Thyroid size change by CT monitoring after sorafenib or sunitinib treatment in patients with renal cell carcinoma: comparison with thyroid function. European journal of radiology, 2012, Volume: 81, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Organ Size; Phenylurea Compounds; Pyridines; Pyrroles; Sorafenib; Sunitinib; Thyroid Gland; Tomography, X-Ray Computed; Treatment Outcome	2012
Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors. Annals of internal medicine, 2006, Nov-07, Volume: 145, Issue:9 Topics: Adult; Antineoplastic Agents; Drug Administration Schedule; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Prospective Studies; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Pyrroles; Sunitinib; Thyroiditis; Thyrotropin	2006
A novel tyrosine-kinase selective inhibitor, sunitinib, induces transient hypothyroidism by blocking iodine uptake. The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:9 Topics: Adult; Aged; Biological Transport; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Iodine; Iodine Radioisotopes; Male; Middle Aged; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Thyrotropin	2007

Other Studies

56 other study(ies) available for pyrroles and Hypothyroidism

Article	Year
Investigation of thyroid function in dogs treated with the tyrosine kinase inhibitor toceranib. Veterinary and comparative oncology, 2020, Volume: 18, Issue:3 Topics: Animals; Dog Diseases; Dogs; Female; Hypothyroidism; Indoles; Male; Neoplasms; Prospective Studies; Pyrroles; Thyroid Gland; Thyrotropin; Thyroxine; United Kingdom	2020
Sunitinib-induced hypothyroidism predicts progression-free survival in metastatic renal cell carcinoma patients. Medical oncology (Northwood, London, England), 2017, Volume: 34, Issue:4 Topics: Aged; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypothyroidism; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Sunitinib	2017
Effects of Toceranib Phosphate on the Hypothalamic-Pituitary-Thyroid Axis in Tumor-Bearing Dogs. Journal of veterinary internal medicine, 2018, Volume: 32, Issue:1 Topics: Animals; Autoantibodies; Dog Diseases; Dogs; Female; Hypothalamus; Hypothyroidism; Indoles; Male; Neoplasms; Pituitary Gland; Prospective Studies; Pyrroles; Thyroglobulin; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	2018
Sunitinib-induced acute severe hypothyroidism in a case of metastatic gastrointestinal stromal tumor: A case report. Journal of cancer research and therapeutics, 2018, Volume: 14, Issue:Supplement Topics: Aged; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Male; Pyrroles; Sunitinib; Thyrotropin	2018
Sunitinib does not block thyroid peroxidase in patients. Thyroid : official journal of the American Thyroid Association, 2014, Volume: 24, Issue:8 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Hypothyroidism; Indoles; Iodide Peroxidase; Kidney Neoplasms; Perchlorates; Pyrroles; Sunitinib; Thyroid Function Tests; Thyrotropin	2014
Hypothyroidism as a predictive clinical marker of better treatment response to sunitinib therapy. Anticancer research, 2014, Volume: 34, Issue:6 Topics: Aged; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Cohort Studies; Female; Follow-Up Studies; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Neoplasm Staging; Pyrroles; Sunitinib; Survival Rate; Treatment Outcome	2014
[Therapeutic significance of sunitinib-induced "off-target" side effects]. Magyar onkologia, 2014, Volume: 58, Issue:3 Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Drug Administration Schedule; Female; Hand-Foot Syndrome; Humans; Hypertension; Hypothyroidism; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Predictive Value of Tests; Pyrroles; Retrospective Studies; Stomatitis; Sunitinib; Treatment Outcome	2014
Hyperlipidemia and hypothyroidism among metastatic renal cell carcinoma patients taking sunitinib malate. Related or unrelated adverse events? Clinical genitourinary cancer, 2015, Volume: 13, Issue:2 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Cholesterol; Female; Humans; Hyperlipidemias; Hypothyroidism; Incidence; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prospective Studies; Pyrroles; Sunitinib; Triglycerides	2015
Is sunitinib-induced hypothyroidism a predictive clinical marker for better response in metastatic renal cell carcinoma patients? Journal of chemotherapy (Florence, Italy), 2016, Volume: 28, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypothyroidism; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome; Young Adult	2016
Long-term Safety of Sunitinib in Metastatic Renal Cell Carcinoma. European urology, 2016, Volume: 69, Issue:2 Topics: Anorexia; Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Dysgeusia; Dyspepsia; Fatigue; Female; Humans; Hypertension; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Mucositis; Nausea; Pyrroles; Stomatitis; Sunitinib; Time Factors	2016
Pleural and pericardial effusions combined with ascites in a patient with severe sunitinib-induced hypothyroidism. Acta clinica Belgica, 2016, Volume: 71, Issue:3 Topics: Antineoplastic Agents; Ascites; Carcinoma, Renal Cell; Fatal Outcome; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Pericardial Effusion; Pleural Effusion; Pyrroles; Sunitinib	2016
Hypothyroidism Side Effect in Patients Treated with Sunitinib or Sorafenib: Clinical and Structural Analyses. PloS one, 2016, Volume: 11, Issue:1 Topics: Carcinoma, Renal Cell; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Models, Molecular; Molecular Docking Simulation; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; Retinoid X Receptor alpha; Sorafenib; Sunitinib	2016
Hypothyroidism and Thyroid Autoimmunity as a Prognostic Biomarker of Better Response in Metastatic Cancer Long-Term Survivors Treated with Sunitinib. Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:9 Topics: Aged; Antineoplastic Agents; Biomarkers; Female; Humans; Hypothyroidism; Immunoenzyme Techniques; Indoles; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Pyrroles; Sunitinib; Survivors; Thyroid Neoplasms; Thyroiditis, Autoimmune; Treatment Outcome	2016
Changes in metabolic profile, iron and ferritin levels during the treatment of metastatic renal cancer - A new potential biomarker? Medical hypotheses, 2016, Volume: 94 Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Renal Cell; Cholesterol; Ferritins; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertriglyceridemia; Hypothyroidism; Indazoles; Indoles; Iron; Kidney Neoplasms; Lipids; Metabolome; Models, Theoretical; Neoplasm Metastasis; Prognosis; Pyrimidines; Pyrroles; Sirolimus; Sulfonamides; Sunitinib; TOR Serine-Threonine Kinases; Triglycerides	2016
Pharmacoepidemiology of Clinically Relevant Hypothyroidism and Hypertension from Sunitinib and Sorafenib. The oncologist, 2017, Volume: 22, Issue:2 Topics: Cohort Studies; Female; Humans; Hypertension; Hypothyroidism; Indoles; Male; Middle Aged; Niacinamide; Pharmacoepidemiology; Phenylurea Compounds; Pyrroles; Sorafenib; Sunitinib	2017
The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluation. British journal of cancer, 2008, Aug-05, Volume: 99, Issue:3 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Prospective Studies; Pyrroles; Sunitinib; Thyroid Function Tests	2008
Documentation of thyroid function in clinical studies with sunitinib: why does it matter? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Nov-01, Volume: 26, Issue:31 Topics: Angiogenesis Inhibitors; Female; Humans; Hypothyroidism; Indoles; Male; Neoplasms; Pyrroles; Sunitinib; Thyroid Function Tests; Treatment Outcome	2008
Is hypothyroidism a clinically relevant toxicity of tyrosine kinase inhibitors? Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:5 Topics: Antineoplastic Agents; Benzenesulfonates; Humans; Hypothyroidism; Indoles; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Risk Assessment; Sorafenib; Sunitinib	2009
Hypothyroidism misdiagnosed as statin intolerance. Annals of internal medicine, 2009, Jul-07, Volume: 151, Issue:1 Topics: Anticholesteremic Agents; Atorvastatin; Diagnostic Errors; Dyslipidemias; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypothyroidism; Male; Middle Aged; Myositis; Pyrroles	2009
[Treatment with sunitinib and hypothyroidism--a case report and overview of literature]. Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2009, Volume: 22, Issue:4 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Sunitinib	2009
Frequent dose interruptions are required for patients receiving oral kinase inhibitor therapy for advanced renal cell carcinoma. American journal of clinical oncology, 2010, Volume: 33, Issue:3 Topics: Administration, Oral; Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Disease Progression; Drug Administration Schedule; Drug Eruptions; Female; Humans; Hypertension; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib	2010
Breast cancer: complete response with the combination of sunitinib and trastuzumab in a patient with grade III ductal carcinoma. Anti-cancer drugs, 2010, Volume: 21 Suppl 1 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Diarrhea; Female; Heart Function Tests; Humans; Hypothyroidism; Indoles; Lymphatic Metastasis; Middle Aged; Paclitaxel; Pyrroles; Remission Induction; Sunitinib; Trastuzumab	2010
Shrinkage of thyroid volume in sunitinib-treated patients with renal-cell carcinoma: a potential marker of irreversible thyroid dysfunction? Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:3 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Fatal Outcome; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Organ Size; Pyrroles; Sunitinib; Thyroid Gland	2010
How does sunitinib cause hypothyroidism? Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib	2010
Sunitinib induces hypothyroidism with a markedly reduced vascularity. Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:3 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Middle Aged; Organ Size; Pyrroles; Sunitinib; Thyroid Gland	2010
[Management of side effects associated with antiangiogenic treatment in renal cell carcinoma]. Bulletin du cancer, 2010, Volume: 97 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Digestive System; Heart; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Lung Injury; Mucous Membrane; Muscle Fatigue; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Sirolimus; Sorafenib; Sunitinib	2010
[Thyroid dysfunction in patients with advanced renal cell carcinoma treated with sunitinib: a multifactorial issue]. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2010, Volume: 57, Issue:10 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Middle Aged; Prevalence; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Sunitinib; Thyroid Hormones; Thyrotropin	2010
Clinical characteristics of thyroid abnormalities induced by sunitinib treatment in Japanese patients with renal cell carcinoma. Endocrine journal, 2010, Volume: 57, Issue:10 Topics: Adult; Aged; Antineoplastic Agents; Atrophy; Carcinoma, Renal Cell; Disease Progression; Female; Humans; Hyperthyroidism; Hypothyroidism; Indoles; Japan; Male; Middle Aged; Organ Size; Protein Kinase Inhibitors; Pyrroles; Regional Blood Flow; Sunitinib; Thyroid Gland; Thyroiditis; Thyrotoxicosis	2010
Sunitinib-induced thyrotoxicosis followed by persistent hypothyroidism with shrinkage of thyroid volume. The Tohoku journal of experimental medicine, 2010, Volume: 222, Issue:1 Topics: Female; Humans; Hypothyroidism; Indoles; Middle Aged; Organ Size; Protein Kinase Inhibitors; Pyrroles; Sunitinib; Thyroid Function Tests; Thyroid Gland; Thyrotoxicosis; Ultrasonography	2010
Hypothyroidism in patients with renal cell carcinoma: blessing or curse? Cancer, 2011, Feb-01, Volume: 117, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Prognosis; Pyridines; Pyrroles; Sorafenib; Sunitinib; Thyrotropin; Treatment Outcome	2011
Kidney cancer: Does hypothyroidism predict clinical outcome? Nature reviews. Urology, 2011, Volume: 8, Issue:1 Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Niacinamide; Phenylurea Compounds; Prognosis; Pyridines; Pyrroles; Sorafenib; Sunitinib	2011
Sunitinib-induced severe hypothyroidism with cardiac compromise. Medical oncology (Northwood, London, England), 2011, Volume: 28 Suppl 1 Topics: Heart Diseases; Humans; Hypothyroidism; Indoles; Male; Middle Aged; Pyrroles; Severity of Illness Index; Sunitinib	2011
Hypothyroidism correlates with a better prognosis in metastatic renal cancer patients treated with sorafenib or sunitinib. World journal of urology, 2011, Volume: 29, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Prognosis; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Survival Rate; Thyrotropin; Thyroxine; Treatment Outcome; Triiodothyronine	2011
[Management of hypothyroidism secondary to tyrosine kinase inhibitors: description of treatment in three distinct clinical settings]. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2011, Volume: 58, Issue:2 Topics: Adult; Benzamides; Benzenesulfonates; Carcinoma, Renal Cell; Choristoma; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Imatinib Mesylate; Indoles; Kidney Neoplasms; Middle Aged; Niacinamide; Phenylurea Compounds; Piperazines; Pleural Diseases; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sunitinib; Thymus Gland; Thyroxine	2011
Response to sunitinib in an adult patient with rhabdoid renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-20, Volume: 29, Issue:18 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Cell Dedifferentiation; Combined Modality Therapy; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Lung Neoplasms; Middle Aged; Nephrectomy; Peripheral Nervous System Diseases; Protein Kinase Inhibitors; Pyrroles; Remission Induction; Rhabdoid Tumor; Sunitinib	2011
Could thyroid dysfunction influence outcome in sunitinib-treated metastatic renal cell carcinoma? Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypothyroidism; Incidence; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Proportional Hazards Models; Pyrroles; Sunitinib; Treatment Outcome	2012
Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression. The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:10 Topics: Aged; Animals; Antineoplastic Agents; Body Weight; Capillaries; Carcinoma, Renal Cell; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Iodide Peroxidase; Kidney Neoplasms; Male; Middle Aged; Prospective Studies; Protein-Tyrosine Kinases; Pyrroles; Rats; Rats, Inbred WKY; Regional Blood Flow; Regression Analysis; Retrospective Studies; Stomach Neoplasms; Sunitinib; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	2011
Incidence of thyroid hormone therapy in patients treated with sunitinib or sorafenib: a cohort study. European journal of cancer (Oxford, England : 1990), 2012, Volume: 48, Issue:7 Topics: Antineoplastic Agents; Benzenesulfonates; Carcinoma, Renal Cell; Cohort Studies; Databases as Topic; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Thyroid Hormones	2012
Does sunitinib-induced hypothyroidism play a role in the activity of sunitinib in metastatic renal cell carcinoma? Chemotherapy, 2012, Volume: 58, Issue:3 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Humans; Hypothyroidism; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Middle Aged; Neoplasm Metastasis; Nephrectomy; Prognosis; Pyrroles; Retrospective Studies; Sunitinib; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	2012
Thyroid dysfunction in patients treated with sunitinib or sorafenib. Clinical genitourinary cancer, 2012, Volume: 10, Issue:4 Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Thyroid Gland; Thyroid Hormones	2012
Extreme hypothyroidism associated with sunitinib treatment for metastatic renal cancer. Journal of chemotherapy (Florence, Italy), 2012, Volume: 24, Issue:4 Topics: Adult; Angiogenesis Inhibitors; Bone Neoplasms; Carcinoma, Renal Cell; Drug Resistance; Fatal Outcome; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Liver Neoplasms; Pyrroles; Severity of Illness Index; Sunitinib; Thyroid Gland; Thyroxine	2012
Successful reintroduction of statin therapy after myositis: was there another cause? The Medical journal of Australia, 2004, May-03, Volume: 180, Issue:9 Topics: Adult; Anticholesteremic Agents; Atorvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Hypothyroidism; Male; Myositis; Pyrroles; Simvastatin	2004
Nongenomic effect of thyroid hormone on free-radical production in human polymorphonuclear leukocytes. The Journal of endocrinology, 2005, Volume: 185, Issue:1 Topics: Adult; Aged; Case-Control Studies; Cell Culture Techniques; Chelating Agents; Diiodothyronines; Dose-Response Relationship, Drug; Egtazic Acid; Female; Free Radicals; GTP-Binding Proteins; Humans; Hyperthyroidism; Hypothyroidism; Indoles; Iodine Radioisotopes; Middle Aged; Naphthalenes; Neutrophil Activation; Neutrophils; Peroxidase; Pertussis Toxin; Protein Kinase C; Pyrroles; Reactive Oxygen Species; Stimulation, Chemical; Superoxides; Thyroid Diseases; Thyroid Hormones; Thyroxine; Triiodothyronine	2005
Tyrosine kinase inhibitors causing hypothyroidism in a patient on levothyroxine. Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:11 Topics: Aged; Benzamides; Drug Interactions; Female; Humans; Hypothyroidism; Imatinib Mesylate; Indoles; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib; Thyroid Function Tests; Thyrotropin; Thyroxine	2006
Summaries for patients. Underactive thyroid function after treatment with sunitinib for gastrointestinal cancer. Annals of internal medicine, 2006, Nov-07, Volume: 145, Issue:9 Topics: Adult; Antineoplastic Agents; Drug Administration Schedule; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Prospective Studies; Protein-Tyrosine Kinases; Pyrroles; Sunitinib; Thyroiditis; Thyrotropin	2006
Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. Journal of the National Cancer Institute, 2007, Jan-03, Volume: 99, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Female; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Sunitinib; Thyroid Function Tests; Thyroid Hormones	2007
Fatigue with sunitinib-induced hypothyroidism. The Lancet. Oncology, 2007, Volume: 8, Issue:2 Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Fatigue; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib	2007
Sunitinib and hypothyroidism. The New England journal of medicine, 2007, Apr-12, Volume: 356, Issue:15 Topics: Angiogenesis Inhibitors; Carcinoma, Renal Cell; Fatigue; Humans; Hypothyroidism; Indoles; Interferon-alpha; Kidney Neoplasms; Pyrroles; Sunitinib	2007
Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activity. Thyroid : official journal of the American Thyroid Association, 2007, Volume: 17, Issue:4 Topics: Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Iodide Peroxidase; Protein-Tyrosine Kinases; Pyrroles; Retrospective Studies; Sunitinib; Thyroid Function Tests	2007
Re: Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. Journal of the National Cancer Institute, 2007, Jun-20, Volume: 99, Issue:12 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Hormone Replacement Therapy; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib; Thyroid Hormones	2007
Re: Hypothyroidism in patients with metastatic renal cell carcinoma treated with sunitinib. Journal of the National Cancer Institute, 2007, Jun-20, Volume: 99, Issue:12 Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib; Thyroid Function Tests; Thyroid Hormones	2007
Sunitinib: new drug. For some gastrointestinal stromal tumours. Prescrire international, 2007, Volume: 16, Issue:90 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Interferon-alpha; Kidney Neoplasms; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles	2007
Tyrosine kinase inhibitors for chronic myelogenous leukemia. The New England journal of medicine, 2007, Oct-11, Volume: 357, Issue:15 Topics: Benzamides; Fusion Proteins, bcr-abl; Humans; Hypothyroidism; Imatinib Mesylate; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Sunitinib	2007
Unanswered questions regarding the management of sunitinib-induced hypothyroidism. Nature clinical practice. Oncology, 2007, Volume: 4, Issue:12 Topics: Antineoplastic Agents; Drug Therapy, Combination; Humans; Hypothyroidism; Indoles; Neoplasms; Pyrroles; Sunitinib; Thyroid Hormones	2007
Acute severe hypothyroidism induced by sunitinib. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2008, Volume: 89, Issue:1 Topics: Acute Disease; Aged; Antineoplastic Agents; Female; Gastrointestinal Stromal Tumors; Humans; Hypothyroidism; Indoles; Pyrroles; Sunitinib	2008
Modulation of vascular KATP channels in hypothyroidism. European journal of pharmacology, 1996, Aug-01, Volume: 309, Issue:1 Topics: Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Guanidines; Hypothyroidism; Male; Pinacidil; Portal Vein; Potassium Channels; Pyrroles; Rats; Vasodilator Agents	1996