| ID Source | ID |
|---|---|
| PubMed CID | 18497 |
| CHEMBL ID | 2105052 |
| CHEBI ID | 168619 |
| SCHEMBL ID | 22120282 |
| MeSH ID | M0073995 |
| Synonym |
|---|
| 1-cyclohexyl-3-[4-(1-hydroxyethyl)phenyl]sulonylurea |
| 3168-01-2 |
| CHEBI:168619 |
| hydroxyhexamide , |
| 1-cyclohexyl-3-[4-(1-hydroxyethyl)phenyl]sulfonylurea |
| n-((cyclohexylamino)carbonyl)-4-(1-hydroxyethyl)benzenesulfonamide |
| f3f26tz9hn , |
| unii-f3f26tz9hn |
| (+/-)-hydroxyhexamide |
| benzenesulfonamide, n-((cyclohexylamino)carbonyl)-4-(1-hydroxyethyl)- |
| 1-cyclohexyl-3-((p-(1-hydroxyethyl)-phenyl)sulfonyl)urea |
| CHEMBL2105052 |
| S5672 |
| CS-4694 |
| HY-B1103 |
| ( inverted exclamation marka)-hydroxyhexamid |
| AKOS026749805 |
| SCHEMBL22120282 |
| BS-16497 |
| BCP29980 |
| ( inverted exclamation marka)-hydroxyhexamid;hydroxyhexamide, (+-)-isomer |
| mfcd00871870 |
| CCG-267768 |
| (+/-)-hydroxyhexamid |
| Q27277583 |
| D83671 |
| DTXSID50953633 |
| n-[(cyclohexylamino)carbonyl]-4-(1-hydroxyethyl)benzenesulfonamide |
| ()-hydroxyhexamid |
The pharmacokinetic profiles of the hypoglycemic agent, acetohexamide (AH) and its major active metabolite, hydroxy hexamide (HH) were studied in three species of laboratory animals.
| Excerpt | Reference | Relevance |
|---|---|---|
| "The pharmacokinetic profiles of the hypoglycemic agent, acetohexamide (AH) and its major active metabolite, hydroxyhexamide (HH) were studied in three species of laboratory animals after intraperitoneal (ipl) administration in comparison with those after intravenous (iv) administration of AH and of the preformed metabolite HH." | ( Comparative pharmacokinetics of acetohexamide and its metabolite, hydroxyhexamide in laboratory animals. Asada, S; Nagamine, S; Nakae, H, 1989) | 0.73 |
| "The pharmacokinetic profile of S(-)-hydroxyhexamide (S-HH), a pharmacologically active metabolite of acetohexamide, was examined in male and female rats." | ( Sex-dependent pharmacokinetics of S(-)-hydroxyhexamide, a pharmacologically active metabolite of acetohexamide, in rats. Akita, H; Imamura, Y; Kaneko, M; Otagiri, M; Shimada, H; Takada, H, 2002) | 0.86 |
| Class | Description |
|---|---|
| sulfonamide | An amide of a sulfonic acid RS(=O)2NR'2. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (19.14) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 1 (7.69%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 12 (92.31%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||