pioglitazone has been researched along with Hypothyroidism in 2 studies
Pioglitazone: A thiazolidinedione and PPAR GAMMA agonist that is used in the treatment of TYPE 2 DIABETES MELLITUS.
pioglitazone : A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypothyroidism was induced by PTU administration, which was indicated by lower serum thyroxine levels." | 4.12 | Cardiovascular protective effects of PPARĪ³ agonists in hypothyroid rats: protection against oxidative stress. ( Ali-Hassanzadeh, M; Baghcheghi, Y; Beheshti, F; Gowhari-Shabgah, A; Hedayati-Moghadam, M; Hosseini, M, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baghcheghi, Y | 1 |
| Beheshti, F | 1 |
| Hosseini, M | 1 |
| Gowhari-Shabgah, A | 1 |
| Ali-Hassanzadeh, M | 1 |
| Hedayati-Moghadam, M | 1 |
| Alhowail, AH | 1 |
2 other studies available for pioglitazone and Hypothyroidism
| Article | Year |
|---|---|
Cardiovascular protective effects of PPARĪ³ agonists in hypothyroid rats: protection against oxidative stress.
Topics: Animals; Antioxidants; Heart; Hypothyroidism; Oxidative Stress; Pioglitazone; PPAR gamma; Propylthio | 2022 |
Pioglitazone ameliorates doxorubicin-induced hypothyroidism and cardiotoxicity in rat models.
Topics: Animals; Cardiotoxicity; Creatine Kinase; Creatine Kinase, MB Form; Doxorubicin; Female; Hypothyroid | 2023 |