Page last updated: 2024-10-19

thioctic acid and Hypothyroidism

thioctic acid has been researched along with Hypothyroidism in 8 studies

Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"The present study evaluates the neuroprotective effect of α-lipoic acid (ALA) and/or metformin (MET) on the behavioral and neurochemical changes induced by hypothyroidism."8.12The Neuroprotective Effect of α-Lipoic Acid and/or Metformin against the Behavioral and Neurochemical Changes Induced by Hypothyroidism in Rat. ( Abdulla, MS; Hosny, EN; Khadrawy, YA; Khoder, NM; Sawie, HG; Sharada, HM, 2022)
"This study investigated possible mechanisms for cardioprotective effects of lipoic acid (LA), quercetin (Q) and resveratrol (R) on oxidative stress related to thyroid hormone alterations in long-term obesity."7.83Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. ( Cheserek, MJ; Karangwa, E; Le, G; Li, L; Shi, Y; Wu, G, 2016)
"The present study evaluates the neuroprotective effect of α-lipoic acid (ALA) and/or metformin (MET) on the behavioral and neurochemical changes induced by hypothyroidism."4.12The Neuroprotective Effect of α-Lipoic Acid and/or Metformin against the Behavioral and Neurochemical Changes Induced by Hypothyroidism in Rat. ( Abdulla, MS; Hosny, EN; Khadrawy, YA; Khoder, NM; Sawie, HG; Sharada, HM, 2022)
"This study investigated possible mechanisms for cardioprotective effects of lipoic acid (LA), quercetin (Q) and resveratrol (R) on oxidative stress related to thyroid hormone alterations in long-term obesity."3.83Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity. ( Cheserek, MJ; Karangwa, E; Le, G; Li, L; Shi, Y; Wu, G, 2016)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Khadrawy, YA1
Khoder, NM1
Sawie, HG1
Sharada, HM1
Hosny, EN1
Abdulla, MS1
Ibrahim, AA1
Mohammed, NA1
Eid, KA1
Abomughaid, MM1
Abdelazim, AM1
Aboregela, AM1
Chen, Y1
Zhou, Z1
Li, XX1
Wang, T1
Tanaka, T1
Masubuchi, Y1
Okada, R1
Nakajima, K1
Nakamura, K1
Masuda, S1
Nakahara, J1
Maronpot, RR1
Yoshida, T1
Koyanagi, M1
Hayashi, SM1
Shibutani, M1
Cheserek, MJ1
Wu, G1
Li, L2
Karangwa, E1
Shi, Y1
Le, G1
G D, X1
J H, P1
H L, S1
L S, Z1
Hamano, Y1
Femiano, F1
Lanza, A1
Buonaiuto, C1
Gombos, F1
Nunziata, M1
Cuccurullo, L1
Cirillo, N1

Trials

2 trials available for thioctic acid and Hypothyroidism

ArticleYear
Alpha-lipoic acid improves endothelial dysfunction in patients with subclinical hypothyroidism.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2010, Volume: 118, Issue:9

    Topics: Aged; Antioxidants; Asymptomatic Diseases; Brachial Artery; Cardiovascular Diseases; Endothelium, Va

2010
Alleviative effects of α-lipoic acid supplementation on acute heat stress-induced thermal panting and the level of plasma nonesterified fatty acids in hypothyroid broiler chickens.
    British poultry science, 2012, Volume: 53, Issue:1

    Topics: Animal Feed; Animals; Body Weight; Chickens; Diet; Dietary Supplements; Fatty Acids, Nonesterified;

2012

Other Studies

6 other studies available for thioctic acid and Hypothyroidism

ArticleYear
The Neuroprotective Effect of α-Lipoic Acid and/or Metformin against the Behavioral and Neurochemical Changes Induced by Hypothyroidism in Rat.
    Neuroendocrinology, 2022, Volume: 112, Issue:11

    Topics: Acetylcholinesterase; Adenosine Triphosphatases; Animals; Brain-Derived Neurotrophic Factor; Dopamin

2022
Hypothyroidism: morphological and metabolic changes in the testis of adult albino rat and the amelioration by alpha-lipoic acid.
    Folia morphologica, 2021, Volume: 80, Issue:2

    Topics: Animals; Hypothyroidism; Male; Rats; Sperm Motility; Spermatogenesis; Testis; Testosterone; Thioctic

2021
Research on the protective effects of antioxidants on metabolic syndrome induced by thyroid dysfunction.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:10

    Topics: Adult; Anthropometry; Antioxidants; Biomarkers; Cross-Sectional Studies; Female; Humans; Hypothyroid

2017
Ameliorating effect of postweaning exposure to antioxidant on disruption of hippocampal neurogenesis induced by developmental hypothyroidism in rats.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:5

    Topics: Animals; Antioxidants; Apoptosis; Doublecortin Protein; Female; Gene Expression Regulation, Developm

2019
Cardioprotective effects of lipoic acid, quercetin and resveratrol on oxidative stress related to thyroid hormone alterations in long-term obesity.
    The Journal of nutritional biochemistry, 2016, Volume: 33

    Topics: Animals; Anti-Obesity Agents; Antihypertensive Agents; Antioxidants; Biomarkers; Cardiotonic Agents;

2016
Burning mouth syndrome and burning mouth in hypothyroidism: proposal for a diagnostic and therapeutic protocol.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2008, Volume: 105, Issue:1

    Topics: Adult; Aged; Antioxidants; Burning Mouth Syndrome; Case-Control Studies; Chi-Square Distribution; Cl

2008