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chlorpromazine and Hypothyroidism

chlorpromazine has been researched along with Hypothyroidism in 12 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"The effect of hypo- and hyperthyroidism on the plasma growth hormone (GH) response to synthetic human growth hormone releasing factor (GRF) was determined in conscious, freely moving rats pretreated with chlorpromazine and antiserum against somatostatin."7.67Plasma growth hormone response to human growth hormone releasing factor in rats administered with chlorpromazine and antiserum against somatostatin. Effects of hypo- and hyperthyroidism. ( Hattori, M; Ihara, T; Ling, N; Shibasaki, T; Tonegawa, Y; Wakabayashi, I, 1985)
"The effect of hypo- and hyperthyroidism on the plasma growth hormone (GH) response to synthetic human growth hormone releasing factor (GRF) was determined in conscious, freely moving rats pretreated with chlorpromazine and antiserum against somatostatin."3.67Plasma growth hormone response to human growth hormone releasing factor in rats administered with chlorpromazine and antiserum against somatostatin. Effects of hypo- and hyperthyroidism. ( Hattori, M; Ihara, T; Ling, N; Shibasaki, T; Tonegawa, Y; Wakabayashi, I, 1985)
"Chlorpromazine was stopped due to concern of NMS."1.46Neuroleptic malignant syndrome with thyroid disorder: An unusual case report. ( Goldman, J; Kanzali, P; Paras, C; Rubin, V; Zhang, F, 2017)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's2 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, F1
Kanzali, P1
Rubin, V1
Paras, C1
Goldman, J1
YANO, S1
TAKEUCHI, K1
KLEIN, JJ1
SEGAL, RL1
WARNER, RR1
ALESHIN, BV1
US, LA1
Beyssen, ML1
Lagorce, JF1
Cledat, D1
Buxeraud, J1
Lombardi, G1
Panza, N1
Cei, S1
Cosimato, F1
Minozzi, M1
Schermann, J1
Chen, HT1
Lu, KH1
Meites, J1
Galen, RS1
Hamatani, Y1
Inoue, M1
Kimura, K1
Shiota, M1
Ohta, M1
Sugano, T1
Wakabayashi, I1
Tonegawa, Y1
Ihara, T1
Hattori, M1
Shibasaki, T1
Ling, N1
Greig, WR1

Reviews

1 review available for chlorpromazine and Hypothyroidism

ArticleYear
Treatment of thyrotoxicosis--the current position. 3. Radioiodine therapy. Special considerations.
    Current medical research and opinion, 1973, Volume: 1, Issue:6

    Topics: Adult; Age Factors; Carbimazole; Chlorpromazine; Female; Heart Diseases; Humans; Hyperthyroidism; Hy

1973

Other Studies

11 other studies available for chlorpromazine and Hypothyroidism

ArticleYear
Neuroleptic malignant syndrome with thyroid disorder: An unusual case report.
    Medicine, 2017, Volume: 96, Issue:39

    Topics: Aged; Antipsychotic Agents; Aripiprazole; Chlorpromazine; Creatine Kinase; Diagnosis, Differential;

2017
[ON THE PITUITARY-ADRENAL FEED-BACK TEST].
    Nihon Naibunpi Gakkai zasshi, 1963, Nov-20, Volume: 39

    Topics: Addison Disease; Adrenal Cortex Hormones; Adrenal Insufficiency; Adrenogenital Syndrome; Anorexia Ne

1963
GALACTORRHEA DUE TO IMIPRAMINE. REPORT OF A CASE.
    The New England journal of medicine, 1964, Sep-03, Volume: 271

    Topics: Amenorrhea; Chlorpromazine; Depression; Depressive Disorder; Female; Galactorrhea; Humans; Hypothyro

1964
[DEMASKING THE EFFECT EXERTED BY SYMPATHETIC IMPULSES ON THE THYROID GLAND].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 58

    Topics: Animals; Autonomic Nervous System; Chlorpromazine; Ganglia; Ganglia, Autonomic; Hypothyroidism; Neur

1964
Influence of dietary iodine on drug-induced hypothyrodism in the rat.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:6

    Topics: Animals; Antithyroid Agents; Chlorpromazine; Clomipramine; Female; Hypothyroidism; Iodine; Lactopero

1999
Radioimmunoassay of thyrotrophin-releasing hormone (TRH) in normal subjects, in abnormal thyroid states and under catecholaminergic influences.
    Acta endocrinologica, 1978, Volume: 87, Issue:1

    Topics: Adenoma; Adult; Bromocriptine; Child; Chlorpromazine; Female; Humans; Hyperthyroidism; Hypothyroidis

1978
[Abnormal galactorrhea and the amenorrhea-galactorrhea syndrome].
    AMB : revista da Associacao Medica Brasileira, 1976, Volume: 22, Issue:10

    Topics: Amenorrhea; Chiari-Frommel Syndrome; Chlorpromazine; Female; Galactorrhea; Humans; Hypothyroidism; I

1976
Effects of hypo- and hyperthyroidism on 5-hydroxytriptophan and chlorpromazine- induced prolactin release in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 151, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Chlorpromazine; Hyperthyroidism; Hypothyroidism; Male; Pituitary Gland

1976
The enzyme diagnosis of myocardial infarction.
    Human pathology, 1975, Volume: 6, Issue:2

    Topics: Angiography; Aspartate Aminotransferases; Cardiac Surgical Procedures; Chlorpromazine; Clinical Enzy

1975
Effects of calmodulin antagonists on hydrogen-translocating shuttles in perfused rat liver.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1

    Topics: Adrenalectomy; Alanine; Aminooxyacetic Acid; Animals; Asparagine; Calcium; Calmodulin; Chlorpromazin

1991
Plasma growth hormone response to human growth hormone releasing factor in rats administered with chlorpromazine and antiserum against somatostatin. Effects of hypo- and hyperthyroidism.
    Neuroendocrinology, 1985, Volume: 41, Issue:4

    Topics: Animals; Cells, Cultured; Chlorpromazine; Growth Hormone-Releasing Hormone; Hyperthyroidism; Hypothy

1985