chloroquine has been researched along with Hypothyroidism in 7 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In two separate experiments, treatment of C3H/He mice bearing transplantable mammary adenocarcinomas (C3HBA) with a regimen of 6-propylthiouracil (PTUra) and 5-fluorouracil (FUra) plus chloroquine phosphate (CP) resulted in complete remissions of 77 and 65%, respectively." | 7.66 | Remissions of mammary adenocarcinoma in hypothyroid mice given 5-fluorouracil and chloroquine phosphate. ( Dagher, RK; Shoemaker, JP, 1979) |
| "In two separate experiments, treatment of C3H/He mice bearing transplantable mammary adenocarcinomas (C3HBA) with a regimen of 6-propylthiouracil (PTUra) and 5-fluorouracil (FUra) plus chloroquine phosphate (CP) resulted in complete remissions of 77 and 65%, respectively." | 3.66 | Remissions of mammary adenocarcinoma in hypothyroid mice given 5-fluorouracil and chloroquine phosphate. ( Dagher, RK; Shoemaker, JP, 1979) |
| "A 19-year-old girl presented with cutaneous lupus erythematosus and hypothyroidism, and developed a thyrotoxic crisis when chloroquine therapy was discontinued." | 3.66 | Cutaneous lupus erythematosus and autoimmune thyroiditis. ( Faber, WR; Maes, EP; van deer Meer-Roosen, CH, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BETTLEY, FR | 1 |
| Munera, Y | 1 |
| Hugues, FC | 1 |
| Le Jeunne, C | 1 |
| Pays, JF | 1 |
| Shoemaker, JP | 1 |
| Dagher, RK | 1 |
| van deer Meer-Roosen, CH | 1 |
| Maes, EP | 1 |
| Faber, WR | 1 |
| Ito, S | 1 |
| Roelofs, RI | 1 |
| Engel, WK | 1 |
| Schimrigk, K | 1 |
7 other studies available for chloroquine and Hypothyroidism
| Article | Year |
|---|---|
CHILBLAIN LUPUS ERYTHEMATOSUS.
Topics: Chilblains; Chloroquine; Fluocinolone Acetonide; Frostbite; Humans; Hydroxychloroquine; Hypothyroidi | 1964 |
Interaction of thyroxine sodium with antimalarial drugs.
Topics: Antimalarials; Chloroquine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypothyroi | 1997 |
Remissions of mammary adenocarcinoma in hypothyroid mice given 5-fluorouracil and chloroquine phosphate.
Topics: Adenocarcinoma; Animals; Chloroquine; Drug Therapy, Combination; Female; Fluorouracil; Hypothyroidis | 1979 |
Cutaneous lupus erythematosus and autoimmune thyroiditis.
Topics: Adult; Chloroquine; Female; Humans; Hypothyroidism; Lupus Erythematosus, Discoid; Thyroid Crisis; Th | 1979 |
[Thyroid hormones].
Topics: Androgens; Chloroquine; Diethylstilbestrol; Estrogens; Female; Humans; Hydrocortisone; Hydroflumethi | 1967 |
Myopathies associated with systemic diseases.
Topics: Alcoholism; Anti-Bacterial Agents; Chloroquine; Collagen Diseases; Endocrine System Diseases; Erythe | 1971 |
[Clinical aspects and therapy of metabolic and other symptomatic muscular diseases].
Topics: Acromegaly; Addison Disease; Adolescent; Adrenal Cortex Hormones; Chloroquine; Cushing Syndrome; Ele | 1972 |