sotalol has been researched along with Hypothyroidism in 3 studies
Sotalol: An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
sotalol : A sulfonamide that is N-phenylmethanesulfonamide in which the phenyl group is substituted at position 4 by a 1-hydroxy-2-(isopropylamino)ethyl group. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is a substudy of a prospective randomized controlled trial (SAFE-Trial) in which amiodarone, sotalol, and placebo for persistent atrial fibrillation were evaluated." | 9.12 | Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. ( Batcher, EL; Hershman, JM; Reda, DJ; Singh, BN; Singh, SN; Tang, XC, 2007) |
| "This is a substudy of a prospective randomized controlled trial (SAFE-Trial) in which amiodarone, sotalol, and placebo for persistent atrial fibrillation were evaluated." | 5.12 | Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. ( Batcher, EL; Hershman, JM; Reda, DJ; Singh, BN; Singh, SN; Tang, XC, 2007) |
| " Because sympathetic activity is greatly enhanced with hyperthyroidism, we studied the effects of isoproterenol and the beta-blocker sotalol on cardiac contractility." | 3.68 | Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations. ( Grupp, G; Grupp, IL; Hewett, TE; Robbins, J; Subramaniam, A, 1993) |
| "Sotalol is a unique beta blocker in not only antagonizing sympathetic stimulation competitively, but also in exerting a potent antiarrhythmic effect by prolonging repolarization." | 2.38 | Is class III antiarrhythmic activity important? ( Singh, BN, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batcher, EL | 1 |
| Tang, XC | 1 |
| Singh, BN | 2 |
| Singh, SN | 1 |
| Reda, DJ | 1 |
| Hershman, JM | 1 |
| Grupp, IL | 1 |
| Subramaniam, A | 1 |
| Hewett, TE | 1 |
| Robbins, J | 1 |
| Grupp, G | 1 |
1 review available for sotalol and Hypothyroidism
| Article | Year |
|---|---|
Is class III antiarrhythmic activity important?
Topics: Animals; Arrhythmias, Cardiac; Humans; Hypothyroidism; In Vitro Techniques; Sotalol | 1990 |
1 trial available for sotalol and Hypothyroidism
| Article | Year |
|---|---|
Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Female; Humans; Hyper | 2007 |
1 other study available for sotalol and Hypothyroidism
| Article | Year |
|---|---|
Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations.
Topics: Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Female; Heart; Hyperthyroidi | 1993 |