isoproterenol has been researched along with Hypothyroidism in 90 studies
Isoproterenol: Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
isoprenaline : A secondary amino compound that is noradrenaline in which one of the hydrogens attached to the nitrogen is replaced by an isopropyl group. A sympathomimetic acting almost exclusively on beta-adrenergic receptors, it is used (mainly as the hydrochloride salt) as a bronghodilator and heart stimulant for the management of a variety of cardiac disorders.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adrenoceptor-mediated responses of the cardiovascular system during propylthiouracil-induced hypothyroidism were investigated." | 7.66 | Changes of adrenoceptor-mediated responses in the pithed rat during propylthiouracil-induced hypothyroidism. ( Borowski, E; Gross, G; Schümann, HJ, 1979) |
| " The possibility that thyroid disease might result in alterations in the plasma proteins binding of drugs has been investigated by studying the binding of propranolol and isoprenaline in patients with hyperthyroidism and hypothyroidism." | 7.66 | Plasma protein binding of propranolol and isoprenaline in hyperthyroidism and hypothyroidism. ( Kelly, JG; McDevitt, DG, 1978) |
| " IPR administered to euthyroid rats in a dosage of 5 mg/kg/day for 4 days induced cardiomegaly." | 5.27 | Study of the factors influencing cardiac growth. I. Comparison of cardiomegaly induced by isoproterenol in euthyroid and thyroidectomized rats. ( Nosztray, K; Szabó, J; Szegi, J; Takács, IE, 1984) |
| "T cells from eu-, hypo- (by propylthiouracil treatment) and hyperthyroid (by thyroxine, T4 administration) mice were purified and specific radioligand binding assays were performed." | 3.73 | Different mitogen-mediated Beta-adrenergic receptor modulation in murine T lymphocytes depending on the thyroid status. ( Barreiro Arcos, ML; Caro, R; Cremaschi, GA; Genaro, AM; Gorelik, G; Klecha, AJ; Silberman, DM, 2005) |
| " To treat bradycardia, the patient was given isoproterenol hydrochloride (ISP: 0." | 3.71 | [A case of bradycardia in a patient with secondary hypothyroidism]. ( Imasyuku, Y; Ishii, T; Iwashita, N; Kitagawa, H; Takahashi, K, 2002) |
| "5 microg of thyroxine/kg of body weight, PO, q 12 h, and 0." | 3.70 | Hemodynamic effects of thyroidectomy in sedentary horses. ( Benson, GJ; Campbell, KL; Constable, PD; Foreman, JH; Freeman, DE; Grubb, TL; Kline, KH; Vischer, CM, 1999) |
| " Because sympathetic activity is greatly enhanced with hyperthyroidism, we studied the effects of isoproterenol and the beta-blocker sotalol on cardiac contractility." | 3.68 | Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations. ( Grupp, G; Grupp, IL; Hewett, TE; Robbins, J; Subramaniam, A, 1993) |
| " Hypothyroidism was induced by treatment of the rats with propylthiouracil for 6 weeks." | 3.68 | Lack of effect of isoproterenol on unloaded velocity of sarcomere shortening in rat cardiac trabeculae. ( de Tombe, PP; ter Keurs, HE, 1991) |
| "Cardiovascular sensitivity to catecholamines was assessed in 15 patients with hypothyroidism (mean [+/- SEM] thyroxine [T4] index 2." | 3.68 | Decreased adrenergic sensitivity in patients with hypothyroidism. ( Dittrich, H; Kennedy, B; Maisel, A; Nicod, P; Polikar, R; Smith, J; Ziegler, M, 1990) |
| " There was a decrease in sensitivity to isoproterenol in spontaneously beating right atria, electrically driven left atria and field-stimulated vas deferens associated with hypothyroidism, with no change in maximum response." | 3.67 | Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness. ( Abel, PW; Fox, AW; Johnson, RD; Juberg, EN; May, JM; Minneman, KP, 1985) |
| " In order to find out whether similar changes exist in the central nervous system, we investigated adrenoceptor-mediated responses in the rat brain cortex during propylthiouracil-induced hypothyroidism." | 3.66 | Effects of thyroid hormone deficiency on pre- and postsynaptic noradrenergic mechanisms in the rat cerebral cortex. ( Brodde, OE; Gross, G; Schümann, HJ, 1980) |
| "1 The effect of hypothyroidism, induced by methimazole, upon the response of the isolated portal vein of the rat to adrenoceptor agonists and antagonists, to angiotensin II and to papaverine has been investigated." | 3.66 | Adrenoreceptor-mediated responses in the isolated portal vein of the hypothyroid rat. ( Handberg, GM; Ishac, EJ; Pennefather, JN; Story, ME; Yoong, YL, 1982) |
| "Adrenoceptor-mediated responses of the cardiovascular system during propylthiouracil-induced hypothyroidism were investigated." | 3.66 | Changes of adrenoceptor-mediated responses in the pithed rat during propylthiouracil-induced hypothyroidism. ( Borowski, E; Gross, G; Schümann, HJ, 1979) |
| " The possibility that thyroid disease might result in alterations in the plasma proteins binding of drugs has been investigated by studying the binding of propranolol and isoprenaline in patients with hyperthyroidism and hypothyroidism." | 3.66 | Plasma protein binding of propranolol and isoprenaline in hyperthyroidism and hypothyroidism. ( Kelly, JG; McDevitt, DG, 1978) |
| "Subclinical hypothyroidism has been linked to cystic fibrosis, and the cystic fibrosis transmembrane conductance regulator (CFTR) shown to be expressed in the thyroid." | 1.36 | Altered ion transport by thyroid epithelia from CFTR(-/-) pigs suggests mechanisms for hypothyroidism in cystic fibrosis. ( Fong, P; Ganta, S; Li, H, 2010) |
| "Methimazole (0." | 1.31 | Effect of hypothyroidism on beta-adrenoceptor-mediated relaxation in the rat thoracic aortae. A time-dependent study. ( Ampong, B; Honda, H; Kogo, H, 2002) |
| " Furthermore, isoproterenol dose-response relationships of these contractile parameters were blunted in the hypothyroid animals and augmented in the hyperthyroid animals compared with euthyroid control animals." | 1.30 | Measurement of intraventricular pressure and cardiac performance in the intact closed-chest anesthetized mouse. ( Lorenz, JN; Robbins, J, 1997) |
| "Hypothyroidism was associated with significant decreases in heart/body weight ratio in wild-type and phospholamban-deficient mice, whereas hyperthyroidism was associated with significant increases in heart/body weight ratio in both groups." | 1.30 | The effect of isoproterenol on phospholamban-deficient mouse hearts with altered thyroid conditions. ( Brittsan, AG; Edes, I; Grupp, G; Grupp, IL; Kiss, E; Kranias, EG, 1999) |
| "Hypothyroidism was induced by providing drinking water containing methimazole and hyperthyroidism was induced by addition of thyroid powder to the diet." | 1.28 | Brown adipose tissue cell respiration in hypo- and hyperthyroidism after stimulation with selective and non selective beta-adrenergic agonists. ( Ilyés, I; Stock, M; Yahata, T, 1991) |
| " IPR administered to euthyroid rats in a dosage of 5 mg/kg/day for 4 days induced cardiomegaly." | 1.27 | Study of the factors influencing cardiac growth. I. Comparison of cardiomegaly induced by isoproterenol in euthyroid and thyroidectomized rats. ( Nosztray, K; Szabó, J; Szegi, J; Takács, IE, 1984) |
| "Prazosin (1 microM) was used to define nonspecific binding of [3H]DHE." | 1.27 | Alpha 1-adrenoreceptors and alpha 1-adrenoreceptor-mediated thyrotropin release in cultures of euthyroid and hypothyroid rat anterior pituitary cells. ( Dieguez, C; Foord, SM; Hall, R; Peters, JR; Scanlon, MF, 1985) |
| "The effects of chronic MtTW15 pituitary adenoma implantation on beta-adrenergic responsiveness, cardiac beta-adrenoreceptors, and muscarinic receptors were studied in the rat." | 1.27 | Beta-adrenergic responsiveness and cardiac autonomic receptors after implantation of the MtTW15 pituitary adenoma in the rat. ( Baker, SP; Katovich, MJ; Nelson, CA, 1987) |
| " The full isoproterenol dose-response curves were similar in all groups." | 1.26 | Unaltered lymphocyte beta-adrenoceptor responsiveness in hyperthyroidism and hypothyroidism. ( Silas, JH; Smith, BM; Yates, RO, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (58.89) | 18.7374 |
| 1990's | 26 (28.89) | 18.2507 |
| 2000's | 10 (11.11) | 29.6817 |
| 2010's | 1 (1.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ballard, B | 1 |
| Torres, LM | 1 |
| Romani, A | 1 |
| Li, H | 1 |
| Ganta, S | 1 |
| Fong, P | 1 |
| Ampong, B | 1 |
| Honda, H | 1 |
| Kogo, H | 1 |
| Ishii, T | 1 |
| Iwashita, N | 1 |
| Imasyuku, Y | 1 |
| Takahashi, K | 1 |
| Kitagawa, H | 1 |
| Haluzik, M | 1 |
| Nedvidkova, J | 2 |
| Bartak, V | 1 |
| Dostalova, I | 1 |
| Vlcek, P | 1 |
| Racek, P | 1 |
| Taus, M | 1 |
| Svacina, S | 1 |
| Alesci, S | 1 |
| Pacak, K | 1 |
| Zung, A | 1 |
| Yaron, A | 1 |
| Altman, Y | 1 |
| Zadik, Z | 1 |
| Klecha, AJ | 1 |
| Barreiro Arcos, ML | 1 |
| Genaro, AM | 1 |
| Gorelik, G | 1 |
| Silberman, DM | 1 |
| Caro, R | 1 |
| Cremaschi, GA | 1 |
| Polak, J | 1 |
| Moro, C | 1 |
| Klimcakova, E | 1 |
| Kovacikova, M | 1 |
| Bajzova, M | 1 |
| Vitkova, M | 1 |
| Kovacova, Z | 1 |
| Sotornik, R | 1 |
| Berlan, M | 1 |
| Viguerie, N | 1 |
| Langin, D | 1 |
| Stich, V | 1 |
| Medina, JH | 1 |
| Wolfman, C | 1 |
| Levi de Stein, M | 1 |
| Tumilasci, O | 1 |
| Houssay, AB | 1 |
| Sundin, U | 1 |
| Mills, I | 2 |
| Fain, JN | 2 |
| Simpson, WW | 3 |
| McNeill, JH | 5 |
| Rodgers, RL | 1 |
| Tachibana, M | 3 |
| Hagino, Y | 5 |
| Szabó, J | 1 |
| Nosztray, K | 1 |
| Takács, IE | 1 |
| Szegi, J | 1 |
| Brodde, OE | 2 |
| Schümann, HJ | 3 |
| Wagner, J | 1 |
| Ui, M | 2 |
| Honma, M | 1 |
| Kunitada, S | 1 |
| Okada, F | 1 |
| Ide, H | 1 |
| Hata, S | 1 |
| Satoh, T | 1 |
| Gross, G | 2 |
| Malbon, CC | 4 |
| Furukawa, H | 1 |
| Loeb, JN | 1 |
| Bilezikian, JP | 1 |
| Smith, BM | 1 |
| Silas, JH | 1 |
| Yates, RO | 1 |
| Rub, HP | 1 |
| Thommen, H | 1 |
| Porzig, H | 1 |
| Stiles, GL | 1 |
| Stadel, JM | 1 |
| De Lean, A | 1 |
| Lefkowitz, RJ | 1 |
| Campbell, R | 1 |
| Oguro, K | 1 |
| Ohguchi, S | 1 |
| Nakashima, M | 3 |
| Yoong, YL | 1 |
| Story, ME | 1 |
| Ishac, EJ | 1 |
| Pennefather, JN | 1 |
| Handberg, GM | 1 |
| Robberecht, P | 1 |
| Pochet, R | 1 |
| Chatelain, P | 1 |
| Verloes, A | 1 |
| Camus, JC | 1 |
| de Neef, P | 1 |
| Christophe, J | 1 |
| MacLeod, KM | 1 |
| Molinero, P | 3 |
| Osuna, C | 2 |
| Guerrero, JM | 3 |
| Grupp, IL | 2 |
| Subramaniam, A | 1 |
| Hewett, TE | 1 |
| Robbins, J | 2 |
| Grupp, G | 2 |
| Kaasik, A | 1 |
| Seppet, EK | 1 |
| Ohisalo, JJ | 1 |
| Ben Cheikh, R | 1 |
| Chomard, P | 1 |
| Dumas, P | 1 |
| Autissier, N | 1 |
| Medina-Martínez, O | 1 |
| García-Sáinz, JA | 4 |
| Kragie, L | 1 |
| Kwon, YW | 1 |
| Smiehorowski, R | 1 |
| Tielens, ET | 1 |
| Forder, JR | 1 |
| Chatham, JC | 1 |
| Marrelli, SP | 1 |
| Ladenson, PW | 1 |
| Lorenz, JN | 1 |
| Garcia-Macias, JF | 1 |
| Rubio, A | 1 |
| Barceló, AC | 1 |
| Bozzini, C | 1 |
| Olivera, MI | 1 |
| Bozzini, CE | 1 |
| Araki, O | 1 |
| Murakami, M | 2 |
| Kamiya, Y | 1 |
| Hosoi, Y | 1 |
| Ogiwara, T | 1 |
| Mizuma, H | 1 |
| Iriuchijima, T | 1 |
| Mori, M | 1 |
| Vischer, CM | 1 |
| Foreman, JH | 1 |
| Constable, PD | 1 |
| Benson, GJ | 1 |
| Kline, KH | 1 |
| Freeman, DE | 1 |
| Campbell, KL | 1 |
| Grubb, TL | 1 |
| Novotny, J | 1 |
| Bourová, L | 1 |
| Málková, O | 1 |
| Svoboda, P | 1 |
| Kolár, F | 1 |
| Brittsan, AG | 1 |
| Kiss, E | 1 |
| Edes, I | 1 |
| Kranias, EG | 1 |
| Ojamaa, K | 1 |
| Klein, I | 1 |
| Sabet, A | 1 |
| Steinberg, SF | 1 |
| Gharami, K | 1 |
| Das, S | 1 |
| Brown, KJ | 1 |
| Summers, RJ | 1 |
| Fregly, MJ | 3 |
| Resch, GE | 2 |
| Nelson, EL | 2 |
| Field, FP | 2 |
| Tyler, PE | 1 |
| Lutherer, LO | 1 |
| Osnes, JB | 1 |
| Katovich, MJ | 2 |
| Barney, CC | 1 |
| Popovic, WJ | 1 |
| Brown, JE | 1 |
| Adamson, JW | 1 |
| Borowski, E | 1 |
| Uematsu, T | 1 |
| Okajima, F | 1 |
| Kelly, JG | 1 |
| McDevitt, DG | 2 |
| Riddell, JG | 1 |
| Hadden, DR | 1 |
| Montgomery, DA | 1 |
| Li, S | 1 |
| Dowell, RT | 1 |
| Atkins, FL | 1 |
| Love, S | 1 |
| Pracyk, JB | 1 |
| Slotkin, TA | 1 |
| Tan, LB | 1 |
| Benjamin, IJ | 1 |
| Clark, WA | 1 |
| Ilyés, I | 2 |
| Yahata, T | 1 |
| Stock, M | 1 |
| Stock, MJ | 1 |
| Venkatesh, N | 1 |
| Lynch, JJ | 1 |
| Uprichard, AC | 1 |
| Kitzen, JM | 1 |
| Singh, BN | 1 |
| Lucchesi, BR | 1 |
| de Tombe, PP | 1 |
| ter Keurs, HE | 1 |
| Polikar, R | 1 |
| Kennedy, B | 1 |
| Maisel, A | 1 |
| Ziegler, M | 1 |
| Smith, J | 1 |
| Dittrich, H | 1 |
| Nicod, P | 1 |
| Gunasekera, RD | 1 |
| Kuriyama, H | 1 |
| Ramanadham, S | 1 |
| Doroudian, A | 1 |
| Beekman, RE | 2 |
| van Hardeveld, C | 2 |
| Simonides, WS | 2 |
| Elks, ML | 1 |
| Manganiello, VC | 1 |
| Nomura, H | 1 |
| Izuhara, K | 1 |
| Nomura, T | 1 |
| Kodama, M | 1 |
| Sugiura, N | 1 |
| Greer, SE | 1 |
| McAdams, S | 1 |
| Greer, MA | 1 |
| Huerta-Bahena, ME | 1 |
| Chess-Williams, R | 1 |
| Coker, SJ | 1 |
| Michel, B | 1 |
| Hernández-Sotomayor, SM | 1 |
| Macías-Silva, M | 1 |
| Plebañski, M | 1 |
| Raasmaja, A | 1 |
| Moolten, N | 1 |
| Lemack, G | 1 |
| Silva, JE | 1 |
| Larsen, PR | 1 |
| Dieguez, C | 1 |
| Foord, SM | 1 |
| Peters, JR | 1 |
| Hall, R | 1 |
| Scanlon, MF | 1 |
| Felt, V | 1 |
| Fox, AW | 1 |
| Juberg, EN | 1 |
| May, JM | 1 |
| Johnson, RD | 1 |
| Abel, PW | 1 |
| Minneman, KP | 1 |
| Nelson, CA | 1 |
| Baker, SP | 1 |
| Holubarsch, C | 1 |
| Hasenfuss, G | 1 |
| Blanchard, E | 1 |
| Alpert, NR | 1 |
| Mulieri, LA | 1 |
| Just, H | 1 |
| Kunos, G | 1 |
| Vermes-Kunos, I | 1 |
| Nickerson, M | 1 |
| Coville, PF | 1 |
| Telford, JM | 1 |
| Bray, GA | 1 |
| Catanzaro, OL | 1 |
| Marzi, A | 1 |
| Kobayashi, K | 1 |
| Rosenqvist, U | 1 |
| Efendić, S | 1 |
| Jereb, B | 1 |
| Ostman, J | 1 |
| Maeda, K | 1 |
| Sekiya, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Thyroid Hormone-Induced Lipolysis: An In Vivo Microdialysis Study[NCT00312715] | 41 participants (Actual) | Observational | 2006-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for isoproterenol and Hypothyroidism
| Article | Year |
|---|---|
The atrial natriuretic peptide- and catecholamine-induced lipolysis and expression of related genes in adipose tissue in hypothyroid and hyperthyroid patients.
Topics: Adult; Aged; Atrial Natriuretic Factor; Body Weight; Catecholamines; Energy Metabolism; Female; Gene | 2007 |
89 other studies available for isoproterenol and Hypothyroidism
| Article | Year |
|---|---|
Effect of thyroid hormone on Mg(2+) homeostasis and extrusion in cardiac cells.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Cell Compartmentation; Cell Separation | 2008 |
Altered ion transport by thyroid epithelia from CFTR(-/-) pigs suggests mechanisms for hypothyroidism in cystic fibrosis.
Topics: Amiloride; Animals; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Cystic Fibrosis | 2010 |
Effect of hypothyroidism on beta-adrenoceptor-mediated relaxation in the rat thoracic aortae. A time-dependent study.
Topics: Acetylcholine; Adrenergic beta-Agonists; Animals; Antithyroid Agents; Aorta, Thoracic; Endothelium, | 2002 |
[A case of bradycardia in a patient with secondary hypothyroidism].
Topics: Aged; Anesthesia, General; Bradycardia; Gastrectomy; Heart Rate; Humans; Hypothyroidism; Isoproteren | 2002 |
Effects of hypo- and hyperthyroidism on noradrenergic activity and glycerol concentrations in human subcutaneous abdominal adipose tissue assessed with microdialysis.
Topics: Abdomen; Adipose Tissue; Adrenergic beta-Agonists; Adult; Case-Control Studies; Female; Glycerol; Hu | 2003 |
Beta-adrenergic hyperresponsiveness in compensated hypothyroidism associated with Down syndrome.
Topics: Adenylyl Cyclases; Adolescent; Adult; Alprostadil; Child; Child, Preschool; Cholera Toxin; Colforsin | 2005 |
Different mitogen-mediated Beta-adrenergic receptor modulation in murine T lymphocytes depending on the thyroid status.
Topics: Adrenergic beta-Agonists; Animals; Cell Proliferation; Cyclic AMP; Down-Regulation; Female; Hyperthy | 2005 |
Thyroid hormone regulation of adrenergic receptors and beta-adrenergic responsiveness in the rat submandibular gland.
Topics: Animals; Dihydroalprenolol; Hyperthyroidism; Hypothyroidism; Isoproterenol; Kinetics; Male; Prazosin | 1984 |
Thyroid-catecholamine interactions in isolated rat brown adipocytes.
Topics: Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Caprylates; Catecholamines; Colforsin; Cyclic AMP | 1984 |
Effect of adrenergic agonists on tension development and rate in atria from euthyroid and hypothyroid rats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Heart Atria; Heart Rate; Hypothyro | 1980 |
Cardiac responsiveness to alpha and beta adrenergic amines: effects of carbachol and hypothyroidism.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Carbachol; Heart; Hypothyroidism; In V | 1981 |
Amylase release from parotid glands of hypothyroid rats. I. Altered responsiveness to adrenergic agents.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Amylases; Animals; Bucladesine; Hypothyroidism; | 1982 |
Study of the factors influencing cardiac growth. I. Comparison of cardiomegaly induced by isoproterenol in euthyroid and thyroidectomized rats.
Topics: Animals; Cardiomegaly; Heart; Hypothyroidism; Isoproterenol; Oxygen Consumption; Rats; Thyroidectomy | 1984 |
Decreased responsiveness of the adenylate cyclase system on left atria from hypothyroid rats.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Electric Stimulation; Hypothyroidism; In Vitro Techniques; I | 1980 |
Adrenergic and cholinergic modulation of extracellular cyclic nucleotides.
Topics: Acetylcholine; Animals; Blood Pressure; Catecholamines; Cyclic AMP; Cyclic GMP; Epinephrine; Humans; | 1980 |
Effects of thyroid hormone deficiency on pre- and postsynaptic noradrenergic mechanisms in the rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Hypothyroidism; I | 1980 |
Liver cell adenylate cyclase and beta-adrenergic receptors. Increased beta-adrenergic receptor number and responsiveness in the hypothyroid rat.
Topics: Adenylyl Cyclases; Animals; Cell Membrane; Enzyme Activation; Female; Glucagon; Hypothyroidism; Isop | 1980 |
Beta-adrenergic receptors and isoproterenol-stimulated potassium transport in erythrocytes from normal and hypothyroid turkeys. Quantitative relation between receptor occupancy and physiologic responsiveness.
Topics: Animals; Biological Transport, Active; Erythrocytes; Female; Hypothyroidism; Isoproterenol; Ouabain; | 1980 |
Unaltered lymphocyte beta-adrenoceptor responsiveness in hyperthyroidism and hypothyroidism.
Topics: Adult; Aged; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Hyperthyroidism; Hypothyr | 1981 |
Quantitative changes in beta-adrenergic responses of isolated atria from hyper- and hypothyroid rats.
Topics: Animals; Dose-Response Relationship, Drug; Heart Atria; Heart Rate; Hyperthyroidism; Hypothyroidism; | 1981 |
Hypothyroidism modulates beta adrenergic receptor adenylate cyclase interactions in rat reticulocytes.
Topics: Adenylyl Cyclases; Animals; Binding, Competitive; Dihydroalprenolol; GTP-Binding Proteins; Hypothyro | 1981 |
Thyroid hormone administration in vivo regulates the activity of hepatic glycogen phosphorylase phosphatase.
Topics: Angiotensin II; Animals; Epinephrine; Female; Glucagon; Hypothyroidism; Isoproterenol; Liver; Phosph | 1982 |
Induction of opposite response of hindlimb vasculature to adrenergic agents in hypothyroid rats.
Topics: Acetylcholine; Animals; Blood Pressure; Clonidine; Heart Rate; Hindlimb; Hypothyroidism; In Vitro Te | 1984 |
Adrenoreceptor-mediated responses in the isolated portal vein of the hypothyroid rat.
Topics: Angiotensin II; Animals; Hypothyroidism; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; P | 1982 |
Decreased secretin and glucagon responsiveness of adenylate cyclase in cardiac membranes from hypothyroid rats.
Topics: Adenylyl Cyclases; Animals; Enzyme Activation; Glucagon; Guanine Nucleotides; Hypothyroidism; Isopro | 1981 |
The effect of carbachol and isoproterenol on the responses of the atria to methoxamine in euthyroid and hypothyroid rats.
Topics: Animals; Carbachol; Heart; Heart Rate; Hypothyroidism; In Vitro Techniques; Isoproterenol; Methoxami | 1980 |
The effect of changes in thyroid state on histamine receptors and adrenoceptors in guinea pig isolated tissues.
Topics: Animals; Diphenhydramine; Female; Guinea Pigs; Heart; Heart Rate; Hypothyroidism; Isoproterenol; Mal | 1980 |
Type II thyroxine 5'-deiodinase in the rat thymus.
Topics: Animals; Cell Membrane; Clonidine; Female; Hypothyroidism; Iodide Peroxidase; Isoproterenol; Male; M | 1995 |
Comparison of normal, hypodynamic, and hyperdynamic mouse hearts using isolated work-performing heart preparations.
Topics: Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Female; Heart; Hyperthyroidi | 1993 |
Enhanced negative inotropic effect of an adenosine A1-receptor agonist in rat left atria in hypothyroidism.
Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Atrial Function; Blotting, Western; Body Weight; Cate | 1994 |
Influence of prolonged fasting on thyroid hormone modulation of lipolysis in isolated epididymal adipocytes of Wistar rats.
Topics: Adenosine Deaminase; Adipose Tissue; Animals; Basal Metabolism; Epididymis; Epinephrine; Fasting; Hy | 1994 |
Hepatocyte homologous beta 2-adrenergic desensitization is associated with a decrease in number of plasma membrane beta 2-adrenoceptors.
Topics: Adenosine Diphosphate Ribose; Adenylyl Cyclases; Alkaline Phosphatase; Animals; Autoradiography; Bin | 1993 |
Rat cardiac calcium channels and their relationships with beta-adrenergic and muscarinic receptors in hypothyroidism.
Topics: Animals; Calcium; Calcium Channels; Carbachol; Dose-Response Relationship, Drug; Heart Rate; Hypothy | 1993 |
Vasoactive intestinal peptide stimulates type II thyroxine 5'-deiodinase and N-acetyltransferase activities in dispersed pineal cells of euthyroid and hypothyroid rats.
Topics: Animals; Arylamine N-Acetyltransferase; Colforsin; Hypothyroidism; In Vitro Techniques; Iodide Perox | 1993 |
Acute L-triiodothyronine administration potentiates inotropic responses to beta-adrenergic stimulation in the isolated perfused rat heart.
Topics: Adrenergic beta-Agonists; Animals; Dose-Response Relationship, Drug; Drug Synergism; Hypothyroidism; | 1996 |
Measurement of intraventricular pressure and cardiac performance in the intact closed-chest anesthetized mouse.
Topics: Anesthesia, General; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart; Heart | 1997 |
Different experimental conditions which regulate type II 5'-deiodinase mRNA in rat Harderian gland.
Topics: Adrenergic beta-Agonists; Animals; Circadian Rhythm; Darkness; Female; Gene Expression Regulation, E | 1997 |
Unmodified erythropoietic response to a beta adrenergic agonist in hypothyroid mice.
Topics: Adrenergic beta-Agonists; Animals; Erythropoiesis; Erythropoietin; Hypothyroidism; Isoproterenol; Ma | 1997 |
Northern analysis of type II iodothyronine deiodinase mRNA in rat Harderian gland.
Topics: Actins; Adrenergic beta-Agonists; Animals; Antithyroid Agents; Blotting, Northern; Harderian Gland; | 1998 |
Hemodynamic effects of thyroidectomy in sedentary horses.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Volume; Body Weight; Electrocard | 1999 |
G proteins, beta-adrenoreceptors and beta-adrenergic responsiveness in immature and adult rat ventricular myocardium: influence of neonatal hypo- and hyperthyroidism.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; GTP-Binding Proteins; Heart Ventricles; Hypert | 1999 |
The effect of isoproterenol on phospholamban-deficient mouse hearts with altered thyroid conditions.
Topics: Animals; Blood Pressure; Calcium-Binding Proteins; Coronary Circulation; Female; Gene Expression Reg | 1999 |
Changes in adenylyl cyclase isoforms as a mechanism for thyroid hormone modulation of cardiac beta-adrenergic receptor responsiveness.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Blotting, Northern; Colforsin; Guanylyl Imidod | 2000 |
Thyroid hormone-induced morphological differentiation and maturation of astrocytes are mediated through the beta-adrenergic receptor.
Topics: Actins; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; | 2000 |
beta(1)- and beta(3)-adrenoceptor mediated smooth muscle relaxation in hypothyroid rat ileum.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dioxoles; Hypothyroidism; Ileum; Imi | 2001 |
Effect of hypothyroidism on responsiveness to beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Animals; Blood Glucose; Blood Pressure; Body Temperature; Drinking Behavio | 1976 |
Reduced beta-adrenergic responsiveness in hypothyroid rats.
Topics: Animals; Antithyroid Agents; Hypothyroidism; Isoproterenol; Male; Phenylephrine; Rats; Skin Temperat | 1975 |
Positive inotropic effect without cyclic AMP elevation after alpha-adrenergic stimulation of perfused hearts from hypothyroid rats.
Topics: Animals; Cyclic AMP; Hypothyroidism; Isoproterenol; Male; Myocardial Contraction; Myocardium; Perfus | 1976 |
Reduced responsiveness to beta-adrenergic stimulation in renal hypertensive rats.
Topics: Animals; Body Temperature; Hypertension, Renal; Hypothyroidism; Isoproterenol; Male; Rats; Receptors | 1978 |
Modulation of in vitro erythropoiesis. Studies with euthyroid and hypothyroid dogs.
Topics: Adenylyl Cyclases; Animals; Colony-Forming Units Assay; Dogs; Erythropoiesis; Hypothyroidism; In Vit | 1979 |
Changes of adrenoceptor-mediated responses in the pithed rat during propylthiouracil-induced hypothyroidism.
Topics: Animals; Atropine; Blood Pressure; Bupranolol; Clonidine; Disease Models, Animal; Electric Stimulati | 1979 |
Effects of phenylephrine and isoproterenol on the activity of cyclic AMP-dependent protein kinase of hypothyroid rat tissues.
Topics: Animals; Centrifugation, Density Gradient; Cyclic AMP; Diaphragm; Hypothyroidism; Isoproterenol; Kid | 1979 |
Adrenergic modulation of insulin secretion in vivo dependent on thyroid states.
Topics: Animals; Blood Glucose; Drug Interactions; Epinephrine; Hyperthyroidism; Hypothyroidism; Insulin; In | 1978 |
Plasma protein binding of propranolol and isoprenaline in hyperthyroidism and hypothyroidism.
Topics: Adult; Blood Proteins; Female; Humans; Hyperthyroidism; Hypothyroidism; Isoproterenol; Male; Middle | 1978 |
Catecholamine sensitivity in hyperthyroidism and hypothyroidism.
Topics: Adult; Catecholamines; Female; Heart Rate; Humans; Hyperthyroidism; Hypothyroidism; Isoproterenol; M | 1978 |
Hormonal activation of glycogen phosphorylase in hepatocytes from hypothyroid rats.
Topics: Animals; Epinephrine; Female; Hypothyroidism; In Vitro Techniques; Isoproterenol; Liver; Phentolamin | 1978 |
Cardiovascular alterations in the hypothyroid rat.
Topics: Animals; Hemodynamics; Hypothyroidism; Isoproterenol; Male; Rats; Rats, Sprague-Dawley; Thyroidectom | 1992 |
Thyroid hormone regulates ontogeny of beta adrenergic receptors and adenylate cyclase in rat heart and kidney: effects of propylthiouracil-induced perinatal hypothyroidism.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Female; Heart; Hypothyroidism; Isoproterenol; Kidney; | 1992 |
beta Adrenergic receptor desensitisation may serve a cardioprotective role.
Topics: Adrenergic beta-Antagonists; Animals; Heart; Heart Diseases; Hypothyroidism; Infusion Pumps; Injecti | 1992 |
Brown adipose tissue cell respiration in hypo- and hyperthyroidism after stimulation with selective and non selective beta-adrenergic agonists.
Topics: Adipose Tissue, Brown; Adrenergic beta-Agonists; Animals; Body Temperature Regulation; Hyperthyroidi | 1991 |
Thermogenic responses to selective and nonselective beta-adrenerg agonists in hypothyroidism of Sprague-Dawley rats.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Animals; Body Weight; Disease Models, Animal; Guanosine Di | 1991 |
Hypothyroidism renders protection against lethal ventricular arrhythmias in a conscious canine model of sudden death.
Topics: Animals; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dogs; Electroencephalography; Electrophysiolo | 1991 |
Lack of effect of isoproterenol on unloaded velocity of sarcomere shortening in rat cardiac trabeculae.
Topics: Animals; Calcium; Female; Heart; Hypothyroidism; Isoproterenol; Male; Myocardial Contraction; Myocar | 1991 |
Decreased adrenergic sensitivity in patients with hypothyroidism.
Topics: Adrenergic beta-Agonists; Electrocardiography, Ambulatory; Epinephrine; Female; Heart Rate; Humans; | 1990 |
The influence of thyroid states upon responses of the rat aorta to catecholamines.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Catecholamines; H | 1990 |
Myocardial and metabolic abnormalities in streptozotocin-diabetic Wistar and Wistar-Kyoto rats.
Topics: Animals; Calcium; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hyperlipidemias | 1990 |
Thyroid status and beta-agonistic effects on cytosolic calcium concentrations in single rat cardiac myocytes activated by electrical stimulation or high-K+ depolarization.
Topics: Animals; Benzofurans; Calcium; Electric Stimulation; Fura-2; Hyperthyroidism; Hypothyroidism; Isopro | 1990 |
Effects of thyroid hormone on regulation of lipolysis and adenosine 3',5'-monophosphate metabolism in 3T3-L1 adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Adipose Tissue; | 1985 |
The interaction of alpha- and beta-adrenergic agonists on amylase release from parotid glands of euthyroid and hypothyroid rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Amylases; Animals; Bucladesine; Calcium; Clonid | 1986 |
Comparison of isoproterenol and dibutyryl adenosine cyclic 3',5'-monophosphate stimulation of thyroxine 5'-deiodinase activity in cultured pineal glands from euthyroid and hypothyroid rats.
Topics: Animals; Bucladesine; Culture Techniques; Dose-Response Relationship, Drug; Hypothyroidism; Iodide P | 1989 |
Hepatocyte beta-adrenergic responsiveness and guanine nucleotide-binding regulatory proteins.
Topics: Adenylyl Cyclases; Adrenalectomy; Animals; Cell Membrane; Cells, Cultured; Cholera Toxin; Cyclic AMP | 1989 |
Ventricular fibrillation is reduced in hypothyroid rats with enhanced myocardial alpha-adrenoceptor responsiveness.
Topics: Anesthesia; Animals; Coronary Disease; Hypothyroidism; Isoproterenol; Male; Myocardial Reperfusion I | 1989 |
Homologous beta-adrenergic desensitization in isolated rat hepatocytes.
Topics: Animals; Cyclic AMP; Female; Glucagon; Hypothyroidism; In Vitro Techniques; Isoproterenol; Liver; Pe | 1987 |
Homologous and heterologous beta-adrenergic desensitization in hepatocytes. Additivity and effect of pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Drug Interactions; Enzym | 1988 |
Effect of thyroid status on catecholamine stimulation of thyroxine 5'-deiodinase in brown adipocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue, Brown; Alprenolol; Animals; Catecholamines; | 1989 |
Alpha 1-adrenoreceptors and alpha 1-adrenoreceptor-mediated thyrotropin release in cultures of euthyroid and hypothyroid rat anterior pituitary cells.
Topics: Animals; Calcimycin; Cells, Cultured; Epinephrine; Hypothyroidism; Isoproterenol; Kinetics; Male; Pi | 1985 |
[The effect of isoprenaline on the levels of cyclic adenosine monophosphate (cAMP) in the lymphocytes of persons in euthyroid, hyperthyroid and hypothyroid states].
Topics: Adult; Aged; Cyclic AMP; Humans; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Isoproterenol | 1985 |
Thyroid status and adrenergic receptor subtypes in the rat: comparison of receptor density and responsiveness.
Topics: Animals; Cerebral Cortex; Ethanolamines; Heart; Heart Rate; Hyperthyroidism; Hypothyroidism; In Vitr | 1985 |
Beta-adrenergic responsiveness and cardiac autonomic receptors after implantation of the MtTW15 pituitary adenoma in the rat.
Topics: Adenoma; Animals; Cardiomegaly; Drinking; Guanylyl Imidodiphosphate; Heart Rate; Hypothyroidism; Iso | 1987 |
Effect of thyroid state on cytosolic free calcium in resting and electrically stimulated cardiac myocytes.
Topics: Animals; Calcium; Cytosol; Electric Stimulation; Hyperthyroidism; Hypothyroidism; Isoproterenol; Mal | 1988 |
Myothermal economy of rat myocardium, chronic adaptation versus acute inotropism.
Topics: Animals; Hypothyroidism; Isoproterenol; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred | 1986 |
Effects of thyroid state on adrenoceptor properties.
Topics: Adrenergic Agonists; Animals; Hypothyroidism; In Vitro Techniques; Isoproterenol; Male; Myocardium; | 1974 |
Influence of thyroid hormones on the responses of smooth muscle to drugs.
Topics: Acetylcholine; Animals; Calcium; Cell Membrane Permeability; Epinephrine; Female; Heart; Histamine; | 1968 |
Adrenergic receptors in rat liver. II. Effects of phenylephrine, isoproterenol and adrenergic blocking agents on gluconeogenesis in perfused liver.
Topics: Animals; Bucladesine; Carbon Radioisotopes; Cyclic AMP; Gluconeogenesis; Glucose; Hypothyroidism; In | 1974 |
Effects of thyroid status and adrenergic blocking drugs on isoproterenol-induced enlargement of the salivary glands.
Topics: Animals; Hypertrophy; Hypothyroidism; Isoproterenol; Organ Size; Phenoxybenzamine; Propranolol; Rats | 1967 |
Cell proliferaton in mouse kidney by isoproterenol and the relationship with the thyroid function.
Topics: Animals; Cell Division; DNA; Hypothyroidism; Iodine Radioisotopes; Isoproterenol; Kidney; Male; Mice | 1974 |
Clinical studies on apexcardiogram. II. Cardiac movement in thyroid dysfunction and coronary heart disease from the point of apexcardiogram.
Topics: Adolescent; Adult; Angina Pectoris; Arteriosclerosis; Coronary Disease; Electrocardiography; Female; | 1971 |
Influence of the hypothyroid state on lipolysis in human adipose tissue in vitro. Hypothyroid state and lipolysis.
Topics: Adenine Nucleotides; Adipose Tissue; Adult; Aged; Female; Glycerol; Humans; Hypothyroidism; In Vitro | 1971 |
Effect of hypothyroid status on myocardial responses to sympathomimetic drugs.
Topics: Animals; Heart; Heart Atria; Hypothyroidism; Isoproterenol; Male; Muscle Contraction; Phenylephrine; | 1971 |