3,3',5-triiodothyroacetic acid has been researched along with Hypothyroidism in 15 studies
tiratricol : A monocarboxylic acid that is (4-hydroxy-3,5-diiodophenyl)acetic acid in which the phenolic hydroxy group has been replaced by a 4-hydroxy-3-iodophenoxy group. It is a thyroid hormone analogue that has been used in the treatment of thyroid hormone resistance syndrome.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
Excerpt | Relevance | Reference |
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"Euthyroid goiter is usually treated with TSH-inhibitory doses of levo-T(4) (L-T(4))." | 6.71 | Comparative efficacy and side effects of the treatment of euthyroid goiter with levo-thyroxine or triiodothyroacetic acid. ( Blanco, A; Brenta, G; Damilano, S; Facco, E; Fretes, O; Gonzalez, E; Gurfinkel, M; Pacenza, N; Pisarev, MA; Schnitman, M, 2003) |
"The diagnosis of fetal hypothyroidism is based at present on measurements of TSH and free thyroxine (FT4) in fetal blood samples obtained by cordocentesis." | 3.70 | Maternal compound W serial measurements for the management of fetal hypothyroidsm. ( Beck-Peccoz, P; Cortelazzi, D; Fisher, DA; Morpurgo, PS; Wu, SY; Zamperini, P, 1999) |
"Following the diagnosis of fetal goitre at 22 and 24 weeks' gestation in two hyperthyroid pregnant women who underwent treatment with 400-500 mg of propylthiouracil in the first weeks of pregnancy, a total of seven fetal blood samplings were performed to evaluate thyroid function before and after the initiation of two different treatment regimens." | 3.69 | Prenatal treatment of fetal hypothyroidism: is there more than one option? ( Acaia, B; Beck-Peccoz, P; Cortelazzi, D; Nicolini, U; Venegoni, E, 1996) |
"In order to compare the effect of 3,5,3'-triiodothyroacetic acid (TRIAC) with those of triiodothyronine (T3) and thyroxine (T4), severely hypothyroid rats (n=56) were infused over 13 days with 1, 2 or 4 nmol/100 g body weight (BW) per day of T3 or 2, 4 or 8 nmol/100 g BW per day of T4 or TRIAC." | 3.69 | Organ-specific effects of 3,5,3'-triiodothyroacetic acid in rats. ( Burger, AG; Juge-Aubry, CE; Liang, H; O'Connell, M, 1997) |
"Euthyroid goiter is usually treated with TSH-inhibitory doses of levo-T(4) (L-T(4))." | 2.71 | Comparative efficacy and side effects of the treatment of euthyroid goiter with levo-thyroxine or triiodothyroacetic acid. ( Blanco, A; Brenta, G; Damilano, S; Facco, E; Fretes, O; Gonzalez, E; Gurfinkel, M; Pacenza, N; Pisarev, MA; Schnitman, M, 2003) |
"After successful treatment of hyperthyroidism, SHBG levels normalized in patients with nIST, but they did not change in patients with nnIST." | 1.28 | Sex hormone-binding globulin measurement in patients with inappropriate secretion of thyrotropin (IST): evidence against selective pituitary thyroid hormone resistance in nonneoplastic IST. ( Beck-Peccoz, P; Brabant, G; Faglia, G; Forloni, F; Marcocci, C; Mariotti, S; Medri, G; Pinchera, A; Roncoroni, R, 1990) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (26.67) | 18.7374 |
1990's | 8 (53.33) | 18.2507 |
2000's | 3 (20.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Scally, MC | 1 |
Hodge, A | 1 |
Brenta, G | 1 |
Schnitman, M | 1 |
Fretes, O | 1 |
Facco, E | 1 |
Gurfinkel, M | 1 |
Damilano, S | 1 |
Pacenza, N | 1 |
Blanco, A | 1 |
Gonzalez, E | 1 |
Pisarev, MA | 1 |
Bentin, J | 1 |
Désir, D | 1 |
Mockel, J | 1 |
Medeiros-Neto, G | 1 |
Kallas, WG | 1 |
Knobel, M | 1 |
Cavaliere, H | 1 |
Mattar, E | 1 |
Heim, J | 1 |
Gavin, LA | 1 |
Livermore, BM | 1 |
Cavalieri, RR | 1 |
Hammond, ME | 1 |
Castle, JN | 1 |
Juge-Aubry, CE | 2 |
Morin, O | 1 |
Pernin, AT | 1 |
Liang, H | 2 |
Philippe, J | 1 |
Burger, AG | 2 |
Carlin, K | 1 |
Carlin, S | 1 |
Nicolini, U | 1 |
Venegoni, E | 1 |
Acaia, B | 1 |
Cortelazzi, D | 3 |
Beck-Peccoz, P | 4 |
Bertola, G | 1 |
Bocchia, M | 1 |
Milani, D | 1 |
Sherman, SI | 1 |
Ringel, MD | 1 |
Smith, MJ | 1 |
Kopelen, HA | 1 |
Zoghbi, WA | 1 |
Ladenson, PW | 1 |
O'Connell, M | 1 |
Morpurgo, PS | 1 |
Zamperini, P | 1 |
Fisher, DA | 1 |
Wu, SY | 1 |
Ciulla, MM | 1 |
Paliotti, R | 1 |
Tortora, G | 1 |
Barelli, MV | 1 |
Buonamici, V | 1 |
Magrini, F | 1 |
Roncoroni, R | 1 |
Mariotti, S | 1 |
Medri, G | 1 |
Marcocci, C | 1 |
Brabant, G | 1 |
Forloni, F | 1 |
Pinchera, A | 1 |
Faglia, G | 1 |
2 trials available for 3,3',5-triiodothyroacetic acid and Hypothyroidism
Article | Year |
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Comparative efficacy and side effects of the treatment of euthyroid goiter with levo-thyroxine or triiodothyroacetic acid.
Topics: Adult; Blood Pressure; Bone and Bones; Goiter; Heart Rate; Humans; Hypothyroidism; Liver; Male; Midd | 2003 |
Augmented hepatic and skeletal thyromimetic effects of tiratricol in comparison with levothyroxine.
Topics: Adult; Aged; Apolipoproteins; Bone and Bones; Cardiovascular System; Cholesterol; Double-Blind Metho | 1997 |
13 other studies available for 3,3',5-triiodothyroacetic acid and Hypothyroidism
Article | Year |
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A report of hypothyroidism induced by an over-the-counter fat loss supplement (Tiratricol).
Topics: Adult; Anti-Obesity Agents; Diet, Fat-Restricted; Dietary Supplements; Fatigue; Female; Humans; Hypo | 2003 |
Triac (3,5,3'-triiodo-thyroacetic acid) induced "pseudohypothyroidism".
Topics: Adult; Female; Humans; Hypothyroidism; Obesity; Thyroid Hormones; Thyrotropin; Triiodothyronine | 1984 |
Triac (3,5,3'-triiodothyroacetic acid) partially inhibits the thyrotropin response to synthetic thyrotropin-releasing hormone in normal and thyroidectomized hypothyroid patients.
Topics: Adult; Female; Humans; Hypothyroidism; Male; Prolactin; Reference Values; Thyroidectomy; Thyrotropin | 1980 |
[Hypothyroidism of central origin corrected by the cessation of Triac therapy].
Topics: Female; Humans; Hypothalamo-Hypophyseal System; Hypothyroidism; Middle Aged; Obesity; Thyroid Hormon | 1982 |
Serum concentration, metabolic clearance, and production rates of 3,5,3'-triiodothyroacetic acid in normal and athyreotic man.
Topics: Humans; Hypothyroidism; Kinetics; Male; Metabolic Clearance Rate; Radioimmunoassay; Thyroxine; Triio | 1980 |
Long-lasting effects of Triac and thyroxine on the control of thyrotropin and hepatic deiodinase type I.
Topics: Animals; Hypothyroidism; Iodide Peroxidase; Kidney; Liver; Male; Organ Specificity; Pituitary Gland; | 1995 |
Possible etiology for euthyroid sick syndrome.
Topics: Animals; Euthyroid Sick Syndromes; Feedback; Gluconeogenesis; Humans; Hypothalamo-Hypophyseal System | 1993 |
Prenatal treatment of fetal hypothyroidism: is there more than one option?
Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Gestational Age; Humans; Hyperthyroidism; Hypothyroidism | 1996 |
[Inhibitory effects of triiodothyroacetic acid on TSH secretion. A case of apparent central hypothyroidism].
Topics: Diagnosis, Differential; Female; Humans; Hypothyroidism; Middle Aged; Thyrotropin; Triiodothyronine | 1996 |
Organ-specific effects of 3,5,3'-triiodothyroacetic acid in rats.
Topics: Animals; Body Weight; Growth Hormone; Hypothyroidism; Iodide Peroxidase; Myocardium; Organ Size; Rat | 1997 |
Maternal compound W serial measurements for the management of fetal hypothyroidsm.
Topics: Biomarkers; Cordocentesis; Diiodothyronines; Female; Fetal Blood; Fetal Diseases; Gestational Age; H | 1999 |
Effects of thyroid hormones on cardiac structure: a tissue characterization study in patients with thyroid disorders before and after treatment.
Topics: Adult; Antithyroid Agents; Collagen; Echocardiography; Electrocardiography; Female; Humans; Hyperthy | 2001 |
Sex hormone-binding globulin measurement in patients with inappropriate secretion of thyrotropin (IST): evidence against selective pituitary thyroid hormone resistance in nonneoplastic IST.
Topics: Adenoma; Adolescent; Adult; Child; Diagnosis, Differential; Drug Resistance; Female; Humans; Hyperth | 1990 |