benserazide has been researched along with Hypothyroidism in 2 studies
Benserazide: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.
benserazide : A carbohydrazide that results from the formal condensation of the carboxy group of DL-serine with the primary amino group of 4-(hydrazinylmethyl)benzene-1,2,3-triol. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as its hydrochloride salt as an adjunct to levodopa in the treatment of parkinsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide has no antiparkinson actions when given alone.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
Excerpt | Relevance | Reference |
---|---|---|
"200 mg of the 4-aromatic amino acid decarboxylase inhibitor benserazide were administered orally to five patients with primary hypothyroidism." | 7.66 | TSH and prolactin stimulation by the decarboxylase inhibitor benserazide in primary hypothyroidism. ( Delitala, G; Devilla, L; Lotti, G, 1980) |
"200 mg of the 4-aromatic amino acid decarboxylase inhibitor benserazide were administered orally to five patients with primary hypothyroidism." | 3.66 | TSH and prolactin stimulation by the decarboxylase inhibitor benserazide in primary hypothyroidism. ( Delitala, G; Devilla, L; Lotti, G, 1980) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Delitala, G | 1 |
Devilla, L | 1 |
Lotti, G | 1 |
Jacoby, JH | 1 |
Mueller, G | 1 |
Wurtman, RJ | 1 |
2 other studies available for benserazide and Hypothyroidism
Article | Year |
---|---|
TSH and prolactin stimulation by the decarboxylase inhibitor benserazide in primary hypothyroidism.
Topics: Adult; Benserazide; Female; Humans; Hydrazines; Hypothyroidism; Male; Middle Aged; Prolactin; Secret | 1980 |
Thyroid state and brain monoamine metabolism.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Dihydroxyphenylalanine; Hyperthyroidism; Hypothyro | 1975 |