thalidomide has been researched along with Hypothyroidism in 14 studies
Thalidomide: A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
thalidomide : A racemate comprising equimolar amounts of R- and S-thalidomide.
2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione : A dicarboximide that is isoindole-1,3(2H)-dione in which the hydrogen attached to the nitrogen is substituted by a 2,6-dioxopiperidin-3-yl group.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thalidomide is highly effective against multiple myeloma, but some patients must discontinue this medication due to adverse effects." | 7.81 | [Thalidomide-associated hypothyroidism in a patient with multiple myeloma]. ( Ikeda, T; Kimura, F; Okamura, I; Sato, K, 2015) |
| "Pomalidomide is an immunomodulatory drug used for relapsed and refractory multiple myeloma (RRMM)." | 5.62 | Hyponatraemia due to hypothyroidism: a rare side effect from pomalidomide. ( Qureshi, A; Rhee, JH, 2021) |
| " Central hypothyroidism is a well-recognized side effect of bexarotene." | 4.89 | Thyroid dysfunction as an unintended side effect of anticancer drugs. ( Appetecchia, M; Baldelli, R; Barnabei, A; Corsello, SM; Paragliola, R; Torino, F, 2013) |
| "Thalidomide is highly effective against multiple myeloma, but some patients must discontinue this medication due to adverse effects." | 3.81 | [Thalidomide-associated hypothyroidism in a patient with multiple myeloma]. ( Ikeda, T; Kimura, F; Okamura, I; Sato, K, 2015) |
| "Primary hypothyroidism is the most common side effect, although thyrotoxicosis and effects on thyroid-stimulating hormone secretion and thyroid hormone metabolism have also been described." | 2.47 | Thyroid dysfunction from antineoplastic agents. ( Hamnvik, OP; Larsen, PR; Marqusee, E, 2011) |
| "Pomalidomide is an immunomodulatory drug used for relapsed and refractory multiple myeloma (RRMM)." | 1.62 | Hyponatraemia due to hypothyroidism: a rare side effect from pomalidomide. ( Qureshi, A; Rhee, JH, 2021) |
| "Hypothyroidism is an often underreported complication of cancer treatment." | 1.35 | Hypothyroidism: a growing complication of cancer treatment. ( Kurtin, SE, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (57.14) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Qureshi, A | 1 |
| Rhee, JH | 1 |
| Torino, F | 1 |
| Barnabei, A | 1 |
| Paragliola, R | 1 |
| Baldelli, R | 1 |
| Appetecchia, M | 1 |
| Corsello, SM | 1 |
| Iams, WT | 1 |
| Hames, ML | 1 |
| Tsai, JP | 1 |
| Dahlman, KB | 1 |
| Talbott, MS | 1 |
| Richards, KL | 1 |
| Reddy, NM | 1 |
| Okamura, I | 1 |
| Ikeda, T | 1 |
| Sato, K | 1 |
| Kimura, F | 1 |
| Kurtin, SE | 1 |
| Hamnvik, OP | 1 |
| Larsen, PR | 1 |
| Marqusee, E | 1 |
| de Savary, N | 1 |
| Lee, R | 1 |
| Vaidya, B | 1 |
| Dimopoulos, MA | 1 |
| Eleutherakis-Papaiakovou, V | 1 |
| Horiuchi, R | 1 |
| Yamamoto, K | 1 |
| Chowta, MN | 1 |
| Chowta, NK | 1 |
| Bermúdez Rodríguez, A | 1 |
| Palazuelos Blanco, LR | 1 |
| González Díaz, CI | 1 |
| Amado Señarís, JA | 1 |
| Menon, S | 1 |
| Habermann, T | 1 |
| Witzig, T | 1 |
| Badros, AZ | 1 |
| Siegel, E | 1 |
| Bodenner, D | 1 |
| Zangari, M | 1 |
| Zeldis, J | 1 |
| Barlogie, B | 1 |
| Tricot, G | 1 |
| Lewis, HB | 1 |
| Albert-Recht, F | 1 |
| Walker, W | 1 |
4 reviews available for thalidomide and Hypothyroidism
| Article | Year |
|---|---|
Thyroid dysfunction as an unintended side effect of anticancer drugs.
Topics: Alemtuzumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agen | 2013 |
Thyroid dysfunction from antineoplastic agents.
Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antica | 2011 |
Adverse effects of thalidomide administration in patients with neoplastic diseases.
Topics: Angiogenesis Inhibitors; Anti-Inflammatory Agents; Antineoplastic Agents; Clinical Trials, Phase II | 2004 |
[Hypothyroidisms induced by drugs].
Topics: Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Endocrine Disruptors; Humans; Hypothyroidism | 2006 |
1 trial available for thalidomide and Hypothyroidism
| Article | Year |
|---|---|
Increased serum tumor necrosis factor α levels in patients with lenalidomide-induced hypothyroidism.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic A | 2015 |
9 other studies available for thalidomide and Hypothyroidism
| Article | Year |
|---|---|
Hyponatraemia due to hypothyroidism: a rare side effect from pomalidomide.
Topics: Aged; Humans; Hyponatremia; Hypothyroidism; Male; Thalidomide; Thyrotropin; Thyroxine; Triiodothyron | 2021 |
[Thalidomide-associated hypothyroidism in a patient with multiple myeloma].
Topics: Aged; Constipation; Humans; Hypothyroidism; Lenalidomide; Male; Multiple Myeloma; Thalidomide; Thyro | 2015 |
Hypothyroidism: a growing complication of cancer treatment.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Female; Humans; Hypothyroidism; Incidence; Iodide Per | 2009 |
Severe hypothyroidism after thalidomide treatment.
Topics: Humans; Hypothyroidism; Immunosuppressive Agents; Male; Middle Aged; Multiple Myeloma; Thalidomide | 2004 |
Hypothyroidism caused by thalidomide.
Topics: Adult; Angiogenesis Inhibitors; Female; Humans; Hypothyroidism; Multiple Myeloma; Obesity; Thalidomi | 2006 |
[Thalidomide-induced hypothyroidism].
Topics: Aged; Female; Humans; Hypothyroidism; Immunosuppressive Agents; Thalidomide | 2007 |
Lenalidomide-associated hypothyroidism.
Topics: Antineoplastic Agents; Female; Humans; Hypothyroidism; Lenalidomide; Lymphoma, B-Cell; Lymphoma, Lar | 2007 |
Hypothyroidism in patients with multiple myeloma following treatment with thalidomide.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Hypothyroidism; Male; Middle Aged; Multiple Myeloma | 2002 |
Cold haemagglutination disease treated by thalidomide.
Topics: Aged; Blood Protein Disorders; Cold Temperature; Cryoglobulins; Female; Hemagglutination; Humans; Hy | 1968 |