ketoconazole has been researched along with Hypothyroidism in 5 studies
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine : A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a patient with type I diabetes mellitus and hypothyroidism who developed frank adrenocortical insufficiency while receiving a high-dose ketoconazole therapy for keratitis caused by Acanthamoeba species." | 3.67 | Adrenal crisis in the setting of high-dose ketoconazole therapy. ( Demerjian, Z; Godine, JE; Khosla, S; Wolfson, JS, 1989) |
| "To investigate a possible inhibitory effect of the antifungal agent ketoconazole on thyroid function, five patients with hypothyroidism and ten normal subjects were treated with ketoconazole at high doses (600 mg/daily in three 20-mg oral doses) for four weeks." | 3.67 | No effect of ketoconazole on thyroid function of normal subjects and hypothyroid patients. ( De Pedrini, P; Montemurro, G; Tommaselli, A, 1988) |
| "In women with CD treated by GK, pregnancy can occur." | 1.38 | Course of pregnancies in women with Cushing's disease treated by gamma-knife. ( Cannavò, S; Cotta, OR; Ferraù, F; Losa, M; Ragonese, M; Torre, ML; Trimarchi, F, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferraù, F | 1 |
| Losa, M | 1 |
| Cotta, OR | 1 |
| Torre, ML | 1 |
| Ragonese, M | 1 |
| Trimarchi, F | 1 |
| Cannavò, S | 1 |
| Khosla, S | 1 |
| Wolfson, JS | 1 |
| Demerjian, Z | 1 |
| Godine, JE | 1 |
| Kitching, NH | 1 |
| Tanner, AR | 1 |
| De Pedrini, P | 1 |
| Tommaselli, A | 1 |
| Montemurro, G | 1 |
5 other studies available for ketoconazole and Hypothyroidism
| Article | Year |
|---|---|
Course of pregnancies in women with Cushing's disease treated by gamma-knife.
Topics: 14-alpha Demethylase Inhibitors; Abortion, Spontaneous; Abruptio Placentae; Adult; Female; Humans; H | 2012 |
Adrenal crisis in the setting of high-dose ketoconazole therapy.
Topics: Acanthamoeba; Acute Disease; Adrenal Cortex Diseases; Amebiasis; Animals; Diabetes Mellitus, Type 1; | 1989 |
Hypothyroidism after treatment with ketoconazole.
Topics: Adult; Candidiasis, Chronic Mucocutaneous; Candidiasis, Oral; Child; Humans; Hypothyroidism; Ketocon | 1986 |
Hypothyroidism after treatment with ketoconazole.
Topics: Candidiasis; Candidiasis, Chronic Mucocutaneous; Humans; Hypothyroidism; Ketoconazole; Male | 1987 |
No effect of ketoconazole on thyroid function of normal subjects and hypothyroid patients.
Topics: Adult; Alkaline Phosphatase; Bilirubin; Female; Humans; Hypothyroidism; Ketoconazole; Liver; Male; T | 1988 |