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phenoxybenzamine and Hypothyroidism

phenoxybenzamine has been researched along with Hypothyroidism in 7 studies

Phenoxybenzamine: An alpha-adrenergic antagonist with long duration of action. It has been used to treat hypertension and as a peripheral vasodilator.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"To investigate the mechanism of the antagonistic effect of Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L-prolin amide monohydrate (CAS 131404-34-7, JTP-2942) on reserpine-induced hypothermia, the role of the autonomic nervous system, adrenal gland, and thyroid gland regarding the effects of JTP-2942 has been studied in mice."7.69Mechanism of the hyperthermic effect of the novel thyrotropin-releasing hormone analogue Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L- prolinamide monohydrate in mice with reserpine-induced hypothermia. ( Iwata, K; Matsushita, M; Ohta, A; Yonemori, F, 1995)
"To investigate the mechanism of the antagonistic effect of Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L-prolin amide monohydrate (CAS 131404-34-7, JTP-2942) on reserpine-induced hypothermia, the role of the autonomic nervous system, adrenal gland, and thyroid gland regarding the effects of JTP-2942 has been studied in mice."3.69Mechanism of the hyperthermic effect of the novel thyrotropin-releasing hormone analogue Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L- prolinamide monohydrate in mice with reserpine-induced hypothermia. ( Iwata, K; Matsushita, M; Ohta, A; Yonemori, F, 1995)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Simpson, WW1
McNeill, JH1
Matsushita, M1
Yonemori, F1
Ohta, A1
Iwata, K1
Männistö, PT1
Ranta, T1
Wagner, J1
Brodde, OE1
Kunos, G1
Vermes-Kunos, I1
Nickerson, M1
Bray, GA1
Hauger-Klevene, JH1
Brown, H1
Zavaleta, J1

Other Studies

7 other studies available for phenoxybenzamine and Hypothyroidism

ArticleYear
Effect of adrenergic agonists on tension development and rate in atria from euthyroid and hypothyroid rats.
    Advances in myocardiology, 1980, Volume: 1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Heart Atria; Heart Rate; Hypothyro

1980
Mechanism of the hyperthermic effect of the novel thyrotropin-releasing hormone analogue Na-((1S,2R)-2-methyl-4-oxocyclopentylcarbonyl)-L-histidyl-L- prolinamide monohydrate in mice with reserpine-induced hypothermia.
    Arzneimittel-Forschung, 1995, Volume: 45, Issue:6

    Topics: Adrenal Medulla; Animals; Body Temperature; Hexamethonium; Hypothermia; Hypothyroidism; Male; Mice;

1995
Neurotransmitter control of thyrotrophin secretion in hypothyroid rats.
    Acta endocrinologica, 1978, Volume: 89, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonidine; Ditiocarb; Fenclonine; Hypothyr

1978
On the presence and distribution of alpha-adrenoceptors in the heart of various mammalian species.
    Naunyn-Schmiedeberg's archives of pharmacology, 1978, Volume: 302, Issue:3

    Topics: Animals; Cats; Cyclic AMP; Cyclic GMP; Electric Stimulation; Female; Guinea Pigs; Heart; Hypothyroid

1978
Effects of thyroid state on adrenoceptor properties.
    Nature, 1974, Aug-30, Volume: 250, Issue:5469

    Topics: Adrenergic Agonists; Animals; Hypothyroidism; In Vitro Techniques; Isoproterenol; Male; Myocardium;

1974
Effects of thyroid status and adrenergic blocking drugs on isoproterenol-induced enlargement of the salivary glands.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 124, Issue:4

    Topics: Animals; Hypertrophy; Hypothyroidism; Isoproterenol; Organ Size; Phenoxybenzamine; Propranolol; Rats

1967
Plasma renin activity in hyper- and hypothyroidism: effect of adrenergic blocking agents.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Blood Pressure; Depressio

1972