eflornithine has been researched along with Hypothyroidism in 1 studies
Eflornithine: An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
eflornithine : A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "DFMO induced hypothyroidism was reversed by the administration of Putrescine." | 3.77 | Reversal of difluoromethylornithine effects by the administration of putrescine in rats. ( Aslam, M; Rehman, R; Soomro, MS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rehman, R | 1 |
| Aslam, M | 1 |
| Soomro, MS | 1 |
1 other study available for eflornithine and Hypothyroidism
| Article | Year |
|---|---|
Reversal of difluoromethylornithine effects by the administration of putrescine in rats.
Topics: Animals; Antineoplastic Agents; Drug Interactions; Eflornithine; Female; Hypothyroidism; Putrescine; | 2011 |