Page last updated: 2024-10-18

hydrogen carbonate and Hypothyroidism

hydrogen carbonate has been researched along with Hypothyroidism in 16 studies

Bicarbonates: Inorganic salts that contain the -HCO3 radical. They are an important factor in determining the pH of the blood and the concentration of bicarbonate ions is regulated by the kidney. Levels in the blood are an index of the alkali reserve or buffering capacity.
hydrogencarbonate : The carbon oxoanion resulting from the removal of a proton from carbonic acid.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Metformin-associated lactic acidosis (MALA) carries a high mortality rate."7.96Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020)
"Metformin-associated lactic acidosis (MALA) carries a high mortality rate."3.96Metformin-associated lactic acidosis: reinforcing learning points. ( Creagh, F; Goonoo, MS; Morris, R; Raithatha, A, 2020)
"Mild hypothyroidism is associated only with a very mild defect in renal acid handling, which appears to be mainly located in the proximal tubule and is compensated by the distal nephron."1.34Thyroid hormone deficiency alters expression of acid-base transporters in rat kidney. ( Kovacikova, J; Mohebbi, N; Nowik, M; Wagner, CA, 2007)
"Hypothyroidism was induced by the intraperitoneal injection of Na131I and animals were studied 10 or more weeks thereafter under anesthesia and compared with their age-matched littermates."1.26Renal acidification in the hypothyroid rat. Evaluation by urinary CO2 tension. ( Kelley, J; Meeks, LA; Michael, UF; Vaamonde, CA, 1981)
"Hypothyroidism was induced by the intraperitoneal injection of Na131I and the animals were studied 10 or more wk thereafter under anesthesia and compared to their age-matched litter-mates."1.26Impaired renal bicarbonate reabsorption in the hypothyroid rat. ( Kelley, J; Michael, UF; Vaamonde, CA, 1979)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's2 (12.50)18.2507
2000's2 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Goonoo, MS1
Morris, R1
Raithatha, A1
Creagh, F1
Gupta, N1
Dwarakanath, V1
Baum, M1
Mohebbi, N1
Kovacikova, J1
Nowik, M1
Wagner, CA1
Pittman, JA1
Beschi, RJ1
Michael, UF4
Kelley, J2
Meeks, LA1
Vaamonde, CA4
Winaver, J1
Sylk, DB1
Teredesai, PR1
Robertson, JS1
Puschett, JB1
Marcos Morales, M1
Purchio Brucoli, HC1
Malnic, G1
Gil Lopes, A1
Tenore, A1
Fasano, A1
Gasparini, N1
Sandomenico, ML1
Ferrara, A1
Di Carlo, A1
Guandalini, S1
Chavez, R1
Cookson, SL1
Oster, JR1
Perez, GO1
Sonneborn, RE1
Okajima, F1
Ui, M1
Maclean, D1
Murison, J1
Griffiths, PD1
Dörr, D2
Wolf, MB2
Maloney, JV2
Deland, EC2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Metformin Overdose in Adult Patients Treated at the University Hospital of Nancy: Single-center Descriptive Retrospective Observational Study[NCT04762966]50 participants (Anticipated)Observational2021-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

16 other studies available for hydrogen carbonate and Hypothyroidism

ArticleYear
Metformin-associated lactic acidosis: reinforcing learning points.
    BMJ case reports, 2020, Sep-02, Volume: 13, Issue:9

    Topics: Acidosis, Lactic; Acute Kidney Injury; Bicarbonates; Continuous Renal Replacement Therapy; Diabetes

2020
Maturation of the Na+/H+ antiporter (NHE3) in the proximal tubule of the hypothyroid adrenalectomized rat.
    American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:3

    Topics: Adrenalectomy; Animals; Animals, Newborn; Bicarbonates; Body Weight; Corticosterone; Female; Glucoco

2004
Thyroid hormone deficiency alters expression of acid-base transporters in rat kidney.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:1

    Topics: Acidosis; Ammonium Chloride; Animals; Antithyroid Agents; Bicarbonates; Blotting, Western; Carrier P

2007
Taste thresholds in hyper- and hypothyroidism.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:6

    Topics: Addison Disease; Bicarbonates; Humans; Hydrochloric Acid; Hyperthyroidism; Hypothyroidism; Myxedema;

1967
Renal acidification in the hypothyroid rat. Evaluation by urinary CO2 tension.
    Canadian journal of physiology and pharmacology, 1981, Volume: 59, Issue:3

    Topics: Animals; Bicarbonates; Carbon Dioxide; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Hypot

1981
Dissociative effects of piretanide on proximal tubular PO4 and HCO3 transport.
    The American journal of physiology, 1980, Volume: 238, Issue:1

    Topics: Animals; Bicarbonates; Biological Transport, Active; Calcium; Dogs; Female; Glomerular Filtration Ra

1980
Role of thyroid hormones in renal tubule acidification.
    Molecular and cellular biochemistry, 1996, Jan-12, Volume: 154, Issue:1

    Topics: Animals; Bicarbonates; Calcium; Hydrogen-Ion Concentration; Hypothyroidism; Kidney Tubules; Kidney T

1996
Thyroxine effect on intestinal Cl-/HCO3- exchange in hypo- and hyperthyroid rats.
    The Journal of endocrinology, 1996, Volume: 151, Issue:3

    Topics: Animals; Bicarbonates; Chlorides; Gastrointestinal Transit; Hyperthyroidism; Hypothyroidism; In Vitr

1996
Impaired urinary acidification in the hypothyroid rat.
    Pflugers Archiv : European journal of physiology, 1976, Feb-24, Volume: 361, Issue:3

    Topics: Acidosis, Renal Tubular; Ammonium Chloride; Animals; Bicarbonates; Diet, Sodium-Restricted; Diuresis

1976
Renal acidification in hypothyroid man.
    Clinical nephrology, 1976, Volume: 6, Issue:3

    Topics: Acidosis, Renal Tubular; Adult; Ammonia; Ammonium Chloride; Bicarbonates; Calcium Chloride; Carbon D

1976
Impaired renal bicarbonate reabsorption in the hypothyroid rat.
    The American journal of physiology, 1979, Volume: 236, Issue:6

    Topics: Animals; Bicarbonates; Biological Transport; Hypothyroidism; Iodine; Kidney; Male; Nephrons; Rats; S

1979
Metabolism of glucose in hyper- and hypo-thyroid rats in vivo. Minor role of endogenous insulin in thyroid-dependent changes in glucose turnover.
    The Biochemical journal, 1979, Aug-15, Volume: 182, Issue:2

    Topics: Animals; Bicarbonates; Blood Glucose; Diabetes Mellitus, Experimental; Hyperthyroidism; Hypothyroidi

1979
Serum enzyme activities in accidental hypothermia and hypothermic myxoedema.
    Clinica chimica acta; international journal of clinical chemistry, 1974, Volume: 52, Issue:2

    Topics: Adult; Aged; Alcohol Oxidoreductases; Aspartate Aminotransferases; Bicarbonates; Body Temperature; C

1974
The anomalous distribution of body water under an alkaline osmotic stress in hypothyroid dogs.
    The Journal of surgical research, 1969, Volume: 9, Issue:8

    Topics: Alkalies; Animals; Bicarbonates; Blood Chemical Analysis; Body Fluids; Carbon Isotopes; Chromium Iso

1969
Water distribution abnormalities in hypothyroid dogs due to acid-base disturbances.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 133, Issue:4

    Topics: Acidosis; Animals; Bicarbonates; Blood; Chlorides; Connective Tissue; Dogs; Erythrocytes; Hydrochlor

1970
[171. Influence of thyroid function on the stress reaction in the dog].
    Langenbecks Archiv fur Chirurgie, 1967, Volume: 319

    Topics: Animals; Bicarbonates; Dogs; Extracellular Space; Hypertonic Solutions; Hypothyroidism; Infusions, P

1967