Page last updated: 2024-10-29

iopanoic acid and Hypothyroidism

iopanoic acid has been researched along with Hypothyroidism in 18 studies

Iopanoic Acid: Radiopaque medium used as diagnostic aid.

Hypothyroidism: A syndrome that results from abnormally low secretion of THYROID HORMONES from the THYROID GLAND, leading to a decrease in BASAL METABOLIC RATE. In its most severe form, there is accumulation of MUCOPOLYSACCHARIDES in the SKIN and EDEMA, known as MYXEDEMA. It may be primary or secondary due to other pituitary disease, or hypothalamic dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Treatment with propylthiouracil (PTU; 0."1.28Effects of hypothyroidism on hypothalamic release of thyrotropin-releasing hormone in rats. ( de Greef, WJ; Klootwijk, W; Rondeel, JM; Visser, TJ, 1992)
"Iopanoic acid (IOP) was administered to newborn rats that were either euthyroid or rendered hypothyroid in utero by propylthiouracil (PTU) or methimazole (MMI) administration to the mothers during gestation and injected with thyroxine on postnatal days 6 and 7."1.28Influence of chronic treatment with iopanoic acid on thyroxine metabolism in the newborn rat. ( Redjem, M; Verdaguer, M; Vigouroux, E, 1990)
"Pretreatment with iopanoic acid blocked the ability of T4 but not of T3 to suppress TRH-induced TSH secretion 2 hr after administration of the respective thyroid hormone."1.27Evidence that thyroxine inhibits either basal or TRH-induced TSH secretion only after conversion to triiodothyronine. ( Greer, MA; Maruta, S, 1988)
"Dithiothreitol (DTT) was required for detectable metabolic reactions: 100 mM DTT was routinely used."1.26Phenolic and tyrosyl ring deiodination of iodothyronines in rat brain homogenates. ( Kaplan, MM; Yaskoski, KA, 1980)
"Iopanoic acid pretreatment did not interfere with the acute TSH response of chronically hypothyroid rats to 70 ng of T3/100 g body weight."1.26Inhibition of intrapituitary thyroxine to 3.5.3'-triiodothyronine conversion prevents the acute suppression of thyrotropin release by thyroxine in hypothyroid rats. ( Dick, TE; Gard, TG; Kaplan, MM; Larsen, PR; Markovitz, BP, 1979)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19908 (44.44)18.7374
1990's7 (38.89)18.2507
2000's3 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Monteforte, R1
Santillo, A1
Lanni, A3
D'Aniello, S1
Baccari, GC1
Larsen, PR3
Silva, JE1
Kaplan, MM3
Yaskoski, KA1
Garcia-Macias, JF1
Molinero, P1
Rubio, A1
Guerrero, JM1
Osuna, C1
Osorio, A1
Ruiz, E1
Ortega, E1
Moreno, M2
Lombardi, A2
Lombardi, P1
Goglia, F2
Petrović, N1
Cvijić, G1
Davidović, V1
Beneduce, L1
Silvestri, E1
Pinna, G1
Dick, TE1
Markovitz, BP1
Gard, TG1
Cageao, LF1
Mignone, IR1
Ricci, CR1
Brignone, CC1
Brignone, JA1
Zaninovich, AA1
Rondeel, JM1
de Greef, WJ1
Klootwijk, W1
Visser, TJ1
Kieffer, JD1
Redjem, M1
Verdaguer, M1
Vigouroux, E1
Maruta, S1
Greer, MA1
St Germain, DL1
West, CD2
Chavré, VJ2
Wolfe, M2
Sparagana, M1
Phillips, G1
Kucera, L1

Reviews

1 review available for iopanoic acid and Hypothyroidism

ArticleYear
Relationships between circulating and intracellular thyroid hormones: physiological and clinical implications.
    Endocrine reviews, 1981,Winter, Volume: 2, Issue:1

    Topics: Acids; Animals; Fasting; Humans; Hypothyroidism; Iodides; Iodine; Iodine Compounds; Iopanoic Acid; K

1981

Trials

1 trial available for iopanoic acid and Hypothyroidism

ArticleYear
Serum thyroxine by competitive protein binding analysis: clinical, statistical and comparative evaluation.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: Blood Chemical Analysis; Blood Proteins; Chemistry, Clinical; Chromatography, Ion Exchange; Clinical

1969

Other Studies

16 other studies available for iopanoic acid and Hypothyroidism

ArticleYear
Morphological and biochemical changes in the Harderian gland of hypothyroid rats.
    The Journal of experimental biology, 2008, Volume: 211, Issue:Pt 4

    Topics: Animals; Antithyroid Agents; Cytochromes c; Cytosol; Gene Expression Regulation; Harderian Gland; Hy

2008
Phenolic and tyrosyl ring deiodination of iodothyronines in rat brain homogenates.
    The Journal of clinical investigation, 1980, Volume: 66, Issue:3

    Topics: Animals; Brain; Dithiothreitol; Hydrogen-Ion Concentration; Hyperthyroidism; Hypothyroidism; In Vitr

1980
Different experimental conditions which regulate type II 5'-deiodinase mRNA in rat Harderian gland.
    Life sciences, 1997, Volume: 61, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Circadian Rhythm; Darkness; Female; Gene Expression Regulation, E

1997
Possible role of GH/IGF-1 in the ovarian function of adult hypothyroid rats.
    Molecular and cellular biochemistry, 1998, Volume: 179, Issue:1-2

    Topics: Animals; Estradiol; Estrus; Female; Growth Hormone; Hypothyroidism; Insulin-Like Growth Factor I; Io

1998
Effect of 3,5-diiodo-L-thyronine on thyroid stimulating hormone and growth hormone serum levels in hypothyroid rats.
    Life sciences, 1998, Volume: 62, Issue:26

    Topics: Animals; Antithyroid Agents; Basal Metabolism; Diiodothyronines; Growth Hormone; Hypothyroidism; Iod

1998
The activity of antioxidant enzymes and the content of uncoupling protein-1 in the brown adipose tissue of hypothyroid rats: comparison with effects of iopanoic acid.
    Physiological research, 2001, Volume: 50, Issue:3

    Topics: Adipose Tissue, Brown; Animals; Antithyroid Agents; Carrier Proteins; Catalase; Contrast Media; Dopa

2001
Are the effects of T3 on resting metabolic rate in euthyroid rats entirely caused by T3 itself?
    Endocrinology, 2002, Volume: 143, Issue:2

    Topics: Animals; Antithyroid Agents; Basal Metabolism; Dactinomycin; Diiodothyronines; Enzyme Inhibitors; Hy

2002
Inhibition of intrapituitary thyroxine to 3.5.3'-triiodothyronine conversion prevents the acute suppression of thyrotropin release by thyroxine in hypothyroid rats.
    The Journal of clinical investigation, 1979, Volume: 64, Issue:1

    Topics: Animals; Cell Nucleus; Hypothyroidism; Iopanoic Acid; Kidney; Liver; Myocardium; Pituitary Gland, An

1979
Effects of thyroid hormones on mitochondrial oxygen consumption in brown adipose tissue and heart from cold-exposed hypothyroid rats.
    Acta endocrinologica, 1992, Volume: 127, Issue:1

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Body Temperature Regulation; Cold Temperature; Glyce

1992
Effects of hypothyroidism on hypothalamic release of thyrotropin-releasing hormone in rats.
    Endocrinology, 1992, Volume: 130, Issue:2

    Topics: Animals; Hypothalamus; Hypothyroidism; In Vitro Techniques; Iopanoic Acid; Male; Median Eminence; Me

1992
Photoaffinity labeling of rat type I iodothyronine deiodinase.
    Endocrinology, 1991, Volume: 129, Issue:2

    Topics: Affinity Labels; Animals; Binding, Competitive; Diazonium Compounds; Hyperthyroidism; Hypothyroidism

1991
Influence of chronic treatment with iopanoic acid on thyroxine metabolism in the newborn rat.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1990, Volume: 22, Issue:6

    Topics: Animals; Animals, Newborn; Hypothyroidism; Iopanoic Acid; Methimazole; Propylthiouracil; Rats; Rats,

1990
Evidence that thyroxine inhibits either basal or TRH-induced TSH secretion only after conversion to triiodothyronine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1988, Volume: 187, Issue:4

    Topics: Animals; Hypothyroidism; Iopanoic Acid; Male; Propylthiouracil; Rats; Thyrotropin; Thyrotropin-Relea

1988
The effects and interactions of substrates, inhibitors, and the cellular thiol-disulfide balance on the regulation of type II iodothyronine 5'-deiodinase.
    Endocrinology, 1988, Volume: 122, Issue:5

    Topics: Animals; Cell Line; Cerebral Cortex; Cycloheximide; Diamide; Dithiothreitol; Hypothyroidism; Iopanoi

1988
A simple method for estimating serum thyroxine concentration in thyroid disease and iodine-treated patients.
    The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:9

    Topics: Chemistry, Clinical; Contrast Media; Diatrizoate; Humans; Hyperthyroidism; Hypothyroidism; Iopanoic

1966
A serum thyroxine method: application in thyroid disease and iodine-treated patients.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25, Issue:9

    Topics: Blood Chemical Analysis; Chromatography; Chromatography, Thin Layer; Contrast Media; Diatrizoate; Hu

1965