hydroxyquinoline

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ChEBI ID: 38774

Members (29)

Research

Studies (107)

Timeframe	Studies, Drugs in This Class (%)	All Drugs %
pre-1990	21 (19.63)	18.7374
1990's	8 (7.48)	18.2507
2000's	14 (13.08)	29.6817
2010's	50 (46.73)	24.3611
2020's	14 (13.08)	2.80

Study Types

Publication Type	Studies, Drugs in This Class (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	5 (1.96%)	6.00%
Case Studies	5 (1.96%)	4.05%
Observational	0 (0.00%)	0.25%
Other	245 (96.08%)	84.16%

Member	Definition	Role
2-(4-hydroxy-2-oxo-1H-quinolin-3-yl)acetic acid pentyl ester		2-(4-hydroxy-2-oxo-1H-quinolin-3-yl)acetic acid pentyl ester
2-(4-hydroxy-2-oxo-1H-quinolin-3-yl)acetic acid propyl ester		2-(4-hydroxy-2-oxo-1H-quinolin-3-yl)acetic acid propyl ester
3-benzyl-4-hydroxyquinolin-2(1H)-one		3-benzyl-4-hydroxyquinolin-2(1H)-one
3-hydroxyquinolin-2(1h)-one		Quinolinediol
5-(phenylmethoxymethyl)-7-(1-piperidinylmethyl)-8-quinolinol		5-(phenylmethoxymethyl)-7-(1-piperidinylmethyl)-8-quinolinol
5-[(2-bromoanilino)methyl]-8-quinolinol		5-[(2-bromoanilino)methyl]-8-quinolinol
5-[(2-fluoroanilino)methyl]-8-quinolinol		5-[(2-fluoroanilino)methyl]-8-quinolinol
5-[[2-(trifluoromethyl)anilino]methyl]-8-quinolinol		5-[[2-(trifluoromethyl)anilino]methyl]-8-quinolinol
5-[[2-furanylmethyl(methyl)amino]methyl]-8-quinolinol		5-[[2-furanylmethyl(methyl)amino]methyl]-8-quinolinol
5-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]methyl]-8-quinolinol		5-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]methyl]-8-quinolinol
5-methyl-8-hydroxyquinoline		tiliquinol
6-chloro-4-hydroxy-3-(phenylmethyl)-1H-quinolin-2-one		6-chloro-4-hydroxy-3-(phenylmethyl)-1H-quinolin-2-one
7-[(4-methyl-1-piperazinyl)methyl]-5-(phenylmethoxymethyl)-8-quinolinol		7-[(4-methyl-1-piperazinyl)methyl]-5-(phenylmethoxymethyl)-8-quinolinol
7-chloro-3-[cyclopropyl(oxo)methyl]-4-hydroxy-1H-quinolin-2-one		7-chloro-3-[cyclopropyl(oxo)methyl]-4-hydroxy-1H-quinolin-2-one
7-hydroxy-4-methyl-1H-quinolin-2-one		7-hydroxy-4-methyl-1H-quinolin-2-one
8-hydroxy-2-methylquinoline		2-Methylquinolin-8-ol
8-hydroxy-7-iodo-5-quinolinesulfonic acid		loretin
N-(4-hydroxy-2-oxo-1H-quinolin-3-yl)heptanamide		N-(4-hydroxy-2-oxo-1H-quinolin-3-yl)heptanamide
N-(4-hydroxy-2-oxo-1H-quinolin-3-yl)pentanamide		N-(4-hydroxy-2-oxo-1H-quinolin-3-yl)pentanamide
N-[(5-bromo-8-hydroxy-7-quinolinyl)-(2-furanyl)methyl]propanamide		N-[(5-bromo-8-hydroxy-7-quinolinyl)-(2-furanyl)methyl]propanamide
N-[(5-bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide		N-[(5-bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide
N-[(5-chloro-8-hydroxy-7-quinolinyl)-(2-furanyl)methyl]acetamide		N-[(5-chloro-8-hydroxy-7-quinolinyl)-(2-furanyl)methyl]acetamide
N-[(5-chloro-8-hydroxy-7-quinolinyl)-(4-methoxyphenyl)methyl]acetamide		N-[(5-chloro-8-hydroxy-7-quinolinyl)-(4-methoxyphenyl)methyl]acetamide
N-[(5-chloro-8-hydroxy-7-quinolinyl)-cyclopropylmethyl]acetamide		N-[(5-chloro-8-hydroxy-7-quinolinyl)-cyclopropylmethyl]acetamide
N-[(5-fluoro-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide		N-[(5-fluoro-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide
N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide		N-[2-furanyl-(8-hydroxy-7-quinolinyl)methyl]-2-methylpropanamide
nsc 3852		5-nitroso-8-quinolinol
uc-112		5-(phenylmethoxymethyl)-7-(1-pyrrolidinylmethyl)-8-quinolinol
viridicatin	A hydroxyquinolone that is 3-hydroxyuinolin-2(1H)-one which is substituted at position 4 by a phenyl groups. Isolated from the mycelium of several Penicillium species, it exhibits strong antibiotic activity against M. tuberculosis and also against B. subtilis, S. aureus and S. cerevisiae.	viridicatin