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ChEBI ID: 46767
| Member | Definition | Role |
|---|---|---|
| 2,2,5,5-tetramethyl-1-pyrrolidinyloxy-3-carboxylic acid | 3-carboxy-PROXYL | |
| 5-oxo-1-(2-phenylethyl)-3-pyrrolidinecarboxylic acid | 5-oxo-1-(2-phenylethyl)-3-pyrrolidinecarboxylic acid | |
| acromelic acid a | A pyrrolidinecarboxylic acid that is siolated from the poisonous mushroom Clitocybe amoenolens. | acromelic acid A |
| domoic acid | An L-proline derivative that is L-proline substituted by a carboxymethyl group at position 3 and a 6-carboxyhepta-2,4-dien-2-yl group at position 4. It is produced by the diatomic algal Pseudo-nitzschia. It is an analogue of kainic acid and a neurotoxin which causes amnesic shellfish poisoning (ASP). | domoic acid |
| kainic acid | kainic acid | |
| spirapril | spirapril | |
| spiraprilat | An azaspiro compound that is spirapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid group. It is the active metabolite of the angiotensin-converting enzyme (ACE) inhibitor spirapril. | spiraprilat |
| Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1,853 (19.64) | 18.7374 |
| 1990's | 3,203 (33.94) | 18.2507 |
| 2000's | 2,376 (25.18) | 29.6817 |
| 2010's | 1,619 (17.16) | 24.3611 |
| 2020's | 386 (4.09) | 2.80 |
| Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
|---|---|---|
| Trials | 70 (0.67%) | 5.53% |
| Reviews | 259 (2.46%) | 6.00% |
| Case Studies | 14 (0.13%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 10,166 (96.74%) | 84.16% |