Canine Distemper

A name for several highly contagious viral diseases of animals, especially canine distemper. In dogs, it is caused by the canine distemper virus (DISTEMPER VIRUS, CANINE). It is characterized by a diphasic fever, leukopenia, gastrointestinal and respiratory inflammation and sometimes, neurologic complications. In cats it is known as FELINE PANLEUKOPENIA.

Synonym
Distemper, Canine
Distemper
Canine Distemper

Excerpt	Reference
"Although canine distemper is enzootic worldwide and has a wide host range, there are no reports of canine distemper virus in crab-eating foxes (Cerdocyon thous) that provide information on virus phylogeny and histopathologic lesions."	( Amorin, RL; Cagnini, DQ; Cortez, A; de Souza, VA; Heinemman, MB; Megid, J; Richtzenhain, LJ; Teixeira, CR, 2009)
"Canine distemper is a highly contagious disease with high incidence and lethality in the canine population."	( Almeida, MR; Bressan, GC; Carvalho, OV; Felix, DM; Ferreira, CG; Fietto, JL; Saraiva, GL; Silva Júnior, A, 2014)
"Canine distemper is a high-impact disease of many mammal species and has caused substantial carnivore population declines."	( Fenton, H; Gottdenker, NL; Keel, MK; Nemeth, NM; Park, AW; Taylor, K; Wilson, JJ; Yabsley, MJ, 2021)
"Canine distemper is a widespread disease affecting both domestic and wild carnivores."	( Cooley, TM; Fitzgerald, SD; Maes, RK; Melotti, JR; O'Brien, DJ; Wise, AG, 2022)
"Canine distemper is caused by canine distemper virus (CDV), a multisystemic infectious disease with a high morbidity and mortality rate in dogs."	( Almanza-Reyes, H; Almeida-Pérez, J; Alvarado-Vera, M; Alvelais-Palacios, JA; Bogdanchikova, N; Gándara-Mireles, JA; Gastelum-Leyva, F; Lares-Asseff, I; Leal-Ávila, MÁ; Loera-Castañeda, V; Patrón-Romero, L; Pena-Jasso, A; Pestryakov, A; Plascencia-López, I, 2022)

Excerpt	Reference
"Canine distemper virus should remain a clinical suspicion for ferrets with skin lesions that do not respond to appropriate therapy, even in animals that were previously vaccinated."	( Benak, J; Hawkins, MG; Koski, MA; Lowenstine, LJ; Luff, JA; White, SD; Zehnder, AM, 2008)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	62 (35.84)	23.3326
1990's	21 (12.14)	12.5806
2000's	34 (19.65)	18.1394
2010's	34 (19.65)	28.8240
2020's	22 (12.72)	9.53

Drug	Relationship Strength	Studies	Trials
dinitrochlorobenzene	low	1	0
creatine	low	1	0
formaldehyde	low	2	0
methanol	low	1	0
mercaptoethanol	low	1	0
azathioprine	low	1	0
barbital	low	1	0
camphor, (+-)-isomer	low	1	0
diazepam	low	1	0
ddt	low	3	0
erythrosine	low	1	0
glutaral	low	1	0
indomethacin	low	1	0
methenamine	low	1	0
pentobarbital	low	1	0
phenobarbital	low	1	0
propofol	low	1	0
sulfanilamide	low	1	0
corticosterone	low	1	0
prednisolone	low	1	0
thymidine	low	1	0
azauridine	low	1	0
idoxuridine	low	1	0
chloramphenicol	low	1	0
tyrosine	low	1	0
methionine	low	1	0
egtazic acid	low	1	0
chloroform	low	1	0
valine	low	1	0
threonine	low	1	0
tryptophan	low	1	0
arginine	low	1	0
phencyclidine	low	1	0
pantothenic acid	low	1	0
methylprednisolone	low	1	0
phenylhydrazine	low	1	0
amprotropine	low	1	0
diphenhydramine hydrochloride	low	1	0
perfluorooctanoic acid	low	1	0
perfluorobutane	low	1	0
citrulline	low	3	0
methamphetamine	low	1	0
eosine yellowish-(ys)	low	1	0
digoxigenin	low	2	0
fluorescein	low	2	0
streptomycin	low	1	0
neon	low	1	0
silver	medium	1	1
barium sulfate	low	1	0
ozone	low	1	0
glutamic acid	low	1	0
ribavirin	low	3	0
delphinidin	low	1	0
medetomidine	low	1	0
perfluorooctane sulfonic acid	low	1	0
clarithromycin	low	1	0
tebuconazole	low	2	0
foxes	low	72	0
caprylates	low	1	0
(3-dimyristyloxypropyl)(dimethyl)(hydroxyethyl)ammonium	low	1	0
methotrexate	low	3	0
proline	low	1	0
biotin	low	1	0
strychnine	low	1	0
retinol	low	1	0
bromochloroacetic acid	low	1	0
cystine	low	1	0
sodium borohydride	low	1	0
myelin basic protein	low	6	0
bilirubin	low	1	0
dinoprostone	low	1	0
phenylephrine hydrochloride	low	3	0
hydrocodone	low	1	0
lead	low	1	0
cysteine	low	1	0
phosphorus	low	1	0
acid phosphatase	low	1	0
dolichol monophosphate	low	1	0
galactocerebroside	low	1	0
interleukin-8	low	4	0
ascorbic acid	low	3	0
transforming growth factor beta	low	3	0
thymic factor, circulating	low	1	0
vitamin b 12	low	1	0
inosine	low	1	0
eye	low	4	0
concanavalin a	low	1	0
metallothionein	low	1	0
leptin	low	2	0

Protein Targets (838)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	10	0	0	10
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
thioredoxin reductase	12	0	0	12
phosphopantetheinyl transferase	9	0	0	9
NFKB1 protein, partial	2	0	0	2
GLS protein	6	0	0	6
thyroid stimulating hormone receptor	9	0	0	9
alpha-galactosidase	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	18	0	0	18
cytochrome P450 2C19 precursor	2	0	0	2
chromobox protein homolog 1	13	0	0	13
flap endonuclease 1	3	0	0	3
DNA polymerase iota isoform a (long)	12	0	0	12
muscarinic acetylcholine receptor M1	4	0	0	4
lethal factor (plasmid)	5	0	0	5
Cytochrome P450 3A4	0	3	1	5
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	6	0	0	6
Chain A, Hyaluronidase, phage associated	0	1	0	1
acetylcholinesterase	11	0	0	11
RAR-related orphan receptor gamma	20	0	0	20
GLI family zinc finger 3	22	0	0	22
AR protein	32	0	0	32
thioredoxin glutathione reductase	6	0	0	6
cytochrome P450 family 3 subfamily A polypeptide 4	12	0	0	12
glucocorticoid receptor [Homo sapiens]	24	0	0	24
retinoic acid nuclear receptor alpha variant 1	24	0	0	24
estrogen-related nuclear receptor alpha	30	0	0	30
estrogen nuclear receptor alpha	35	0	0	35
vitamin D (1,25- dihydroxyvitamin D3) receptor	15	0	0	15
IDH1	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
thyroid hormone receptor beta isoform 2	24	0	0	24
nuclear factor erythroid 2-related factor 2 isoform 1	22	0	0	22
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
geminin	20	0	0	20
lamin isoform A-delta10	19	0	0	19
Polyphenol oxidase 2	0	1	0	2
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	1	0	1
Alpha-2B adrenergic receptor	0	0	1	1
Spike glycoprotein	7	0	1	8
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	8	0	0	8
Chain A, Ferritin light chain	6	0	0	6
interleukin 8	8	0	0	8
SMAD family member 2	11	0	0	11
ATAD5 protein, partial	7	0	0	7
Fumarate hydratase	2	0	0	2
SMAD family member 3	11	0	0	11
TDP1 protein	23	0	0	23
Microtubule-associated protein tau	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	17	0	0	17
EWS/FLI fusion protein	6	0	0	6
retinoid X nuclear receptor alpha	19	0	0	19
farnesoid X nuclear receptor	15	0	0	15
pregnane X nuclear receptor	19	0	0	19
G	10	0	0	10
polyprotein	2	0	0	2
P53	1	0	0	1
peroxisome proliferator-activated receptor delta	13	0	0	13
peroxisome proliferator activated receptor gamma	18	0	0	18
arylsulfatase A	5	0	0	5
aryl hydrocarbon receptor	11	0	0	11
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	15	0	0	15
thyroid stimulating hormone receptor	14	0	0	14
activating transcription factor 6	12	0	0	12
v-jun sarcoma virus 17 oncogene homolog (avian)	14	0	0	14
Histone H2A.x	10	0	0	10
Bloom syndrome protein isoform 1	8	0	0	8
peripheral myelin protein 22 isoform 1	6	0	0	6
hemoglobin subunit beta	1	0	0	1
cellular tumor antigen p53 isoform a	4	0	0	4
heat shock protein beta-1	11	0	0	11
peripheral myelin protein 22	9	0	0	9
survival motor neuron protein isoform d	9	0	0	9
cytochrome P450 3A4 isoform 1	8	0	0	8
M-phase phosphoprotein 8	4	0	0	4
muscleblind-like protein 1 isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	8	3	2	13
ATP-binding cassette sub-family C member 3	0	9	0	9
Multidrug resistance-associated protein 4	0	9	0	11
Bile salt export pump	0	3	0	3
Voltage-dependent calcium channel gamma-2 subunit	15	0	0	15
Bile salt export pump	0	13	0	13
Interferon beta	11	0	0	11
HLA class I histocompatibility antigen, B alpha chain	10	0	0	10
Cellular tumor antigen p53	23	0	0	23
Gamma-aminobutyric acid receptor subunit beta-1	8	3	2	13
Gamma-aminobutyric acid receptor subunit delta	8	3	2	13
Gamma-aminobutyric acid receptor subunit gamma-2	8	3	2	13
Glutamate receptor 2	15	2	1	18
Gamma-aminobutyric acid receptor subunit alpha-5	8	3	2	13
Gamma-aminobutyric acid receptor subunit alpha-3	8	3	2	13
Gamma-aminobutyric acid receptor subunit gamma-1	8	3	2	13
Gamma-aminobutyric acid receptor subunit alpha-2	8	3	2	13
Gamma-aminobutyric acid receptor subunit alpha-4	8	3	2	13
Gamma-aminobutyric acid receptor subunit gamma-3	8	3	2	13
Gamma-aminobutyric acid receptor subunit alpha-6	8	3	2	13
Nuclear receptor ROR-gamma	11	0	0	11
Gamma-aminobutyric acid receptor subunit alpha-1	8	3	2	13
Gamma-aminobutyric acid receptor subunit beta-3	8	3	2	13
Gamma-aminobutyric acid receptor subunit beta-2	8	3	2	13
GABA theta subunit	8	3	2	13
Inositol hexakisphosphate kinase 1	10	0	0	10
Canalicular multispecific organic anion transporter 1	0	7	0	7
ATPase family AAA domain-containing protein 5	10	0	0	10
Ataxin-2	11	0	0	11
Gamma-aminobutyric acid receptor subunit epsilon	8	3	2	13
Protein-arginine deiminase type-4	0	4	0	4
cytochrome P450 2C9, partial	10	0	0	10
glp-1 receptor, partial	7	0	0	7
Skn7p	0	0	0	1
apical membrane antigen 1, AMA1	4	0	0	4
nonstructural protein 1	3	0	0	3
67.9K protein	9	0	0	9
Janus kinase 2 (a protein tyrosine kinase)	0	1	0	1
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Orotidine 5'-phosphate decarboxylase	0	1	0	1
Integrin beta-3	2	0	1	3
Integrin alpha-IIb	2	0	1	3
Alpha-synuclein	2	2	0	4
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, 2-oxoglutarate Oxygenase	7	0	0	7
Chain A, Cruzipain	5	0	0	5
USP1 protein, partial	6	0	0	6
aldehyde dehydrogenase 1 family, member A1	10	0	0	10
vitamin D3 receptor isoform VDRA	10	0	0	10
DNA polymerase kappa isoform 1	6	0	0	6
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	2	0	0	2
Inositol monophosphatase 1	3	0	0	3
Solute carrier organic anion transporter family member 1B3	0	5	0	7
Solute carrier organic anion transporter family member 1B1	0	5	0	6
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
Chain A, Beta-lactoglobulin	0	0	1	1
Chain A, Beta-lactoglobulin	0	0	1	1
UDP-3-O-acyl-N-acetylglucosamine deacetylase	0	0	1	1
hypoxia-inducible factor 1 alpha subunit	11	0	0	11
caspase 7, apoptosis-related cysteine protease	3	0	0	3
estrogen receptor 2 (ER beta)	13	0	0	13
progesterone receptor	16	0	0	16
caspase-3	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	2	0	0	2
thyrotropin-releasing hormone receptor	3	0	0	3
mitogen-activated protein kinase 1	8	0	0	8
nuclear receptor ROR-gamma isoform 1	3	0	0	3
Caspase-2	0	0	1	1
cytochrome P450 2D6	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
streptokinase A precursor	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Methionine--tRNA ligase, mitochondrial	0	0	1	1
Luciferase	5	0	0	5
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
General amino-acid permease GAP1	0	0	0	1
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
ATP-dependent translocase ABCB1	0	2	0	3
Potassium voltage-gated channel subfamily H member 2	0	4	0	4
pregnane X receptor	4	0	0	4
GALC protein	3	0	0	3
Thrombopoietin	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
thyroid hormone receptor beta isoform a	6	0	0	6
serine/threonine-protein kinase mTOR isoform 1	2	0	0	2
Solute carrier family 22 member 2	0	1	0	2
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 3	0	2	0	2
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	2	2	4
Androgen receptor	0	5	0	5
C-8 sterol isomerase	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	3	0	3
Solute carrier family 22 member 2	0	2	0	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Smad3	4	0	0	4
PINK1	1	0	0	1
Parkin	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	6	0	0	6
neutrophil cytosol factor 1	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	2	0	0	2
ras-related protein Rab-9A	3	0	0	3
Solute carrier family 2, facilitated glucose transporter member 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 3	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Caspase-7	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
caspase-3	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
Epidermal growth factor receptor	0	2	0	2
Vascular endothelial growth factor receptor 2	0	1	0	1
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
CREB-binding protein	0	1	0	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Fatty acid-binding protein, liver	0	2	0	2
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	1	2	4
Albumin	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	0	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	0	3
Neuronal acetylcholine receptor subunit alpha-4	1	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	0	3
Neuronal acetylcholine receptor subunit beta-2	1	2	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	3	7
Translocator protein	0	1	1	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	3	6
5-hydroxytryptamine receptor 1A	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	4	2	6
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	3	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	3	5
Gamma-aminobutyric acid receptor subunit beta-2	0	2	3	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	2	0	2
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
PAX8	0	0	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Chain A, Beta-lactamase	2	0	0	2
Vpr	3	0	0	3
Rap guanine nucleotide exchange factor 3	2	0	0	2
Glutathione S-transferase omega-1	0	1	0	1
TAR DNA-binding protein 43	4	0	0	4
regulator of G-protein signaling 4	3	0	0	3
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	2	0	2
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 6	0	1	0	3
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	2	0	2
Solute carrier family 22 member 8	0	1	0	3
Solute carrier family 22 member 6	0	2	0	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
endonuclease IV	2	0	0	2
eyes absent homolog 2 isoform a	2	0	0	2
D(1A) dopamine receptor	2	0	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Genome polyprotein	0	1	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
hypothetical protein, conserved	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
relaxin receptor 1 isoform 1	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
large T antigen	0	1	0	1
P-selectin	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	3	0	0	3
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Glutamate receptor ionotropic, NMDA 2D	0	2	0	2
Excitatory amino acid transporter 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
Carbonic anhydrase 1	0	3	0	7
Carbonic anhydrase 2	0	3	2	9
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, NMDA 1	0	5	1	8
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	1	7
Glutamate receptor ionotropic, NMDA 2B	0	4	1	7
Glutamate receptor ionotropic, NMDA 2C	0	4	1	8
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	0	3
Glutamate receptor ionotropic, NMDA 2A	0	3	0	3
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	3	0	3
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	4	1	7
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	4	1	7
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	4	1	7
Mu-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Thymidine kinase	0	2	0	3
Thymidine kinase, cytosolic	0	3	0	5
Thymidine phosphorylase	0	0	0	2
Thymidine kinase	0	0	0	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
glucocerebrosidase	1	0	0	1
cytochrome P450 2D6 isoform 1	1	0	0	1
cytochrome P450 2C9 precursor	2	0	0	2
neuropeptide S receptor isoform A	1	0	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
Prostaglandin G/H synthase 2	0	1	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	3
Procathepsin L	0	1	1	2
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Adenosine receptor A1	0	1	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	2	0	2
Caspase-1	0	0	0	1
Adenosine receptor A2a	0	1	0	2
Substance-P receptor	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	1	0	1
Prostaglandin G/H synthase 2	0	4	1	5
Prostaglandin G/H synthase 2	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Histamine H2 receptor	2	0	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Multidrug and toxin extrusion protein 1	0	1	0	1
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain A, ADENOSINE DEAMINASE	0	1	0	1
Chain A, ADENOSINE DEAMINASE	0	1	0	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	2	2
Purine nucleoside phosphorylase	0	0	0	1
Adenosylhomocysteinase	0	1	0	4
Adenosine deaminase	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1B adrenergic receptor	0	1	1	2
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	1	1	2
Glutaminyl-peptide cyclotransferase	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	1	3
Sodium-dependent serotonin transporter	0	0	1	1
Amine oxidase [flavin-containing] B	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Trace amine-associated receptor 1	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	0	0	1
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Fatty acid synthase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	4	0	4
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
dopamine D1 receptor	1	0	0	1
ClpP	1	0	0	1
15-lipoxygenase, partial	2	0	0	2
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
DNA polymerase beta	1	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
DNA polymerase eta isoform 1	1	0	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	4	0	5
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	0	1	1
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	3
5-hydroxytryptamine receptor 2C	0	2	0	3
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	0	0	1
PPM1D protein	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Glucocorticoid receptor	0	4	1	10
Glycine receptor subunit alpha-1	0	5	0	5
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Muscarinic acetylcholine receptor M1	0	2	1	4
Muscarinic acetylcholine receptor M3	0	2	1	4
Muscarinic acetylcholine receptor M4	0	2	1	4
Muscarinic acetylcholine receptor M5	0	2	1	4
Muscarinic acetylcholine receptor M2	0	2	1	4
Muscarinic acetylcholine receptor M1	0	0	2	3
Cytochrome P450 2B6	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Muscarinic acetylcholine receptor M4	0	0	1	2
Delta-type opioid receptor	0	1	0	2
Kappa-type opioid receptor	0	0	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Mu-type opioid receptor	0	1	0	2
Cholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2D6	0	1	0	1
Cytochrome P450 2C9	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Cytochrome P450 2C19	0	1	0	1
Histone acetyltransferase KAT8	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	1	2
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	2	3
Cytochrome P450 2A6	0	1	1	2
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	1	0	1
Estrogen receptor beta	0	2	0	2
Glutamate 5-kinase	0	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Aldo-keto reductase family 1 member B1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
5-hydroxytryptamine receptor 2B	0	2	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Amyloid-beta precursor protein	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	2	0	0	2
NS5	0	0	1	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Adenosine receptor A3	0	1	0	1
Replicase polyprotein 1ab	0	0	1	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Angiotensin-converting enzyme 2	0	0	1	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	0	1
Glycine receptor subunit alpha-1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	0	1
Gamma-aminobutyric acid receptor subunit rho-2	0	0	0	1
Glycine receptor subunit beta	0	1	0	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 10	0	0	1	2
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 12	0	1	0	3
Carbonic anhydrase 2	0	1	1	2
Cholinesterase	0	1	0	1
Carbonic anhydrase 3	0	1	0	3
Acetylcholinesterase	0	1	0	1
Carbonic anhydrase 4	0	1	0	3
Carbonic anhydrase 6	0	2	0	4
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	2	0	5
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase 7	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase 9	0	2	0	4
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 15	0	1	0	3
Carbonic anhydrase 13	0	1	0	2
Protein argonaute-2	0	0	1	1
Carbonic anhydrase 14	0	1	0	3
Carbonic anhydrase 5B, mitochondrial	0	1	0	4
Cytochrome P450 14alpha-demethylase	0	0	1	1
Sterol 14-alpha demethylase	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidine kinase	0	0	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Plasma kallikrein	0	0	0	2
Myeloperoxidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Stromelysin-1	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
SLC16A10 protein	0	0	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Monocarboxylate transporter 10	0	0	0	2
Phospholipase A-2-activating protein	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Arginase 1	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (173)

Protein Targets (838)

Canine Distemper

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (173)

Drugs Studied (103)

Protein Targets (838)