Tuberculosis, Urogenital

A general term for MYCOBACTERIUM infections of any part of the UROGENITAL SYSTEM in either the male or the female.

Synonym
Urogenital Tuberculosis
Tuberculosis, Urogenital

Excerpt	Reference
"Modern therapy of urogenital tuberculosis is divisible into conservative, purely medicamentous treatment, possibly in combination with corticosteroids, and operative therapy, procedures preserving organs and rational eradication of tuberculous processes having to be carefully weighed against each other."	( Eisenberger, F; Schmiedt, E, 1978)

Excerpt	Reference
"Urogenital tuberculosis has not decreased in incidence like other forms of tuberculosis and this is not to be expected in the coming years."	( Haubensak, K; Osterhage, HR, 1975)

Excerpt	Reference
"Modern therapy of urogenital tuberculosis is divisible into conservative, purely medicamentous treatment, possibly in combination with corticosteroids, and operative therapy, procedures preserving organs and rational eradication of tuberculous processes having to be carefully weighed against each other."	( Eisenberger, F; Schmiedt, E, 1978)
"The present therapy of the urogenital tuberculosis is based on the effective medicaments (rifampizin, isonicotinic acid hydrazid, streptomycin, and ethambutol)."	( Kalweit, H; Lenk, S; Rothkopf, M, 1978)
"Previous studies have shown that urogenital tuberculosis (GuTb) patients treated or untreated with regular anti-Tb regimen excrete comparatively high levels of urinary stone forming constituents than normal subjects."	( Jenita, X; Kalaiselvi, P; Muthu, V; Pragasam, V; Srinivasan, S; Varalakshmi, P, 2004)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	300 (87.21)	23.3326
1990's	15 (4.36)	12.5806
2000's	14 (4.07)	18.1394
2010's	12 (3.49)	28.8240
2020's	3 (0.87)	9.53

Drug	Relationship Strength	Studies	Trials
chlorine	low	1	0
dimethyl sulfoxide	low	1	0
niacin	low	32	0
pyrazinamide	low	32	0
pyridoxine	low	5	0
uracil	medium	1	1
diatrizoic acid	low	1	0
p-aminohippuric acid	low	1	0
antipyrine	low	1	0
bisoprolol	low	2	0
verapamil	low	1	0
carbonyl cyanide m-chlorophenyl hydrazone	low	1	0
iothalamic acid	low	2	0
isoniazid	medium	122	2
mebendazole	low	1	0
metronidazole	low	1	0
ofloxacin	low	1	0
aminosalicylic acid	medium	51	1
phenazopyridine	low	1	0
praziquantel	low	1	0
sulfadimethoxine	low	1	0
sulfamethizole	low	1	0
sulfamethoxazole	low	1	0
sulfobromophthalein	low	1	0
trimethoprim	low	2	0
mitomycin	low	1	0
prednisolone	low	9	0
reserpine	low	1	0
hydroxyproline	low	1	0
prednisone	low	4	0
androsterone	medium	2	1
etiocholanolone	medium	1	1
cyanides	low	2	0
kanamycin a	low	7	0
edetic acid	low	1	0
barbituric acid	low	1	0
norethindrone	low	1	0
cycloserine	low	19	0
mannitol	medium	1	1
methylprednisolone	low	2	0
n-vinyl-2-pyrrolidinone	low	1	0
iodohippuric acid	low	5	0
cyacetacide	low	2	0
oxazoles	low	1	0
pyrazines	medium	3	1
hydrazine	low	3	0
cyanoacetic acid	low	2	0
betamethasone	low	1	0
lucanthone hydrochloride	low	1	0
6-methyluracil	medium	1	1
ethambutol	low	32	0
d-alpha tocopherol	low	2	0
streptomycin	medium	131	1
nitroxoline	medium	1	1
technetium	low	1	0
gold	low	1	0
chlormerodrin	low	1	0
phenyl acetate	low	3	0
fludrocortisone	low	1	0
4-methoxyamphetamine	low	1	0
trimethoprim sulfamethizole	low	1	0
xenon radioisotopes	low	1	0
pregnanetriol	medium	1	1
zd 7288	low	1	0
moxifloxacin	low	1	0
technetium tc 99m pentetate	low	2	0
cortisone	low	9	0
fibrin	low	1	0
retinol	low	1	0
prothionamide	low	1	0
phenylthiourea	low	5	0
enclomiphene	medium	1	1
thiourea	low	1	0
ethionamide	low	8	0
thiocarlide	low	2	0
oxychlorosene	low	1	0
sodium dodecyl sulfate	low	1	0
17-ketosteroids	medium	3	1
amphotericin b	low	1	0
phthioic acid	low	1	0
arsenic	low	1	0
indinavir sulfate	low	1	0
rifamycin sv	low	1	0
nitrofurantoin	medium	1	1
thioacetazone	low	4	0
candicidin	medium	1	1
nystatin a1	low	1	0
pituitrin	low	1	0
enerbol	low	1	0
rifamycins	low	1	0
clove	low	1	0
gastrins	low	1	0
cellulose	low	1	0
cardiovascular agents	low	1	0
piperidines	low	1	0
ascorbic acid	medium	2	1
oxytetracycline, anhydrous	low	3	0
warfarin	low	1	0
sybr green i	low	1	0
caseins	low	1	0
hyaluronoglucosaminidase	low	2	0
viomycin	low	6	0
rifampin	low	52	0

Protein Targets (729)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
5-hydroxytryptamine receptor 2C	0	1	1	2
5-hydroxytryptamine receptor 2A	0	4	1	5
5-hydroxytryptamine receptor 1A	0	4	1	5
5-hydroxytryptamine receptor 1B	0	3	1	4
5-hydroxytryptamine receptor 1D	0	1	1	2
5-hydroxytryptamine receptor 1F	0	1	1	2
5-hydroxytryptamine receptor 2B	0	2	1	3
5-hydroxytryptamine receptor 6	0	0	1	1
Sodium-dependent serotonin transporter	0	6	1	7
Sodium-dependent serotonin transporter	0	1	0	1
5-hydroxytryptamine receptor 7	0	0	1	1
5-hydroxytryptamine receptor 5A	0	0	1	1
5-hydroxytryptamine receptor 5B	0	0	1	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 4	0	0	1	1
5-hydroxytryptamine receptor 3B	0	0	1	1
estrogen-related nuclear receptor alpha	34	0	0	34
Carbonic anhydrase 1	0	6	0	7
Chain A, 2-oxoglutarate Oxygenase	13	0	0	13
Microtubule-associated protein tau	17	0	0	17
thioredoxin glutathione reductase	9	0	0	9
Smad3	5	0	0	5
euchromatic histone-lysine N-methyltransferase 2	21	0	0	21
microphthalmia-associated transcription factor isoform 9	0	2	0	2
Carbonic anhydrase 2	0	5	0	6
Tyrosine-protein phosphatase non-receptor type 1	0	0	1	1
Chain A, HADH2 protein	12	0	0	12
Chain B, HADH2 protein	12	0	0	12
Chain A, Cruzipain	8	0	0	8
interleukin 8	11	0	0	11
phosphopantetheinyl transferase	13	0	0	13
GLS protein	11	0	0	11
glucocorticoid receptor [Homo sapiens]	29	0	0	29
farnesoid X nuclear receptor	16	0	0	16
peroxisome proliferator-activated receptor delta	19	0	0	19
vitamin D (1,25- dihydroxyvitamin D3) receptor	23	0	0	23
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	13	0	0	13
nuclear factor erythroid 2-related factor 2 isoform 1	26	0	0	26
peripheral myelin protein 22	9	0	0	9
lamin isoform A-delta10	24	0	0	24
Cytochrome P450 1A2	0	2	0	2
Cytochrome P450 3A4	0	8	0	9
Cytochrome P450 2D6	0	3	0	3
Cytochrome P450 2C9	0	7	1	8
Cytochrome P450 2C19	0	2	0	2
Nuclear receptor ROR-gamma	10	0	0	10
Potassium voltage-gated channel subfamily H member 2	0	6	0	7
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	5
Chain A, retinol dehydratase	0	1	0	1
acetylcholinesterase	9	0	0	9
RAR-related orphan receptor gamma	30	0	0	30
TDP1 protein	26	0	0	26
GLI family zinc finger 3	39	0	0	39
AR protein	35	0	0	35
estrogen receptor 2 (ER beta)	17	0	0	17
progesterone receptor	17	0	0	17
retinoic acid nuclear receptor alpha variant 1	30	0	0	30
retinoid X nuclear receptor alpha	26	0	0	26
pregnane X nuclear receptor	25	0	0	25
estrogen nuclear receptor alpha	45	0	0	45
v-jun sarcoma virus 17 oncogene homolog (avian)	16	0	0	16
histone acetyltransferase KAT2A isoform 1	8	0	0	8
Gamma-aminobutyric acid receptor subunit pi	15	2	0	17
Voltage-dependent calcium channel gamma-2 subunit	13	0	0	13
Sex hormone-binding globulin	0	0	5	5
Corticosteroid-binding globulin	0	5	0	5
Glucose-6-phosphate 1-dehydrogenase	0	3	0	3
Androgen receptor	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	15	2	0	17
Gamma-aminobutyric acid receptor subunit delta	15	2	0	17
Gamma-aminobutyric acid receptor subunit gamma-2	15	2	0	17
Glutamate receptor 2	13	0	0	13
Gamma-aminobutyric acid receptor subunit alpha-5	15	2	0	17
Gamma-aminobutyric acid receptor subunit alpha-3	15	2	0	17
Gamma-aminobutyric acid receptor subunit gamma-1	15	2	0	17
Gamma-aminobutyric acid receptor subunit alpha-2	15	2	0	17
Gamma-aminobutyric acid receptor subunit alpha-4	15	2	0	17
Gamma-aminobutyric acid receptor subunit gamma-3	15	2	0	17
Gamma-aminobutyric acid receptor subunit alpha-6	15	2	0	17
Solute carrier organic anion transporter family member 1A1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	15	2	0	17
Gamma-aminobutyric acid receptor subunit beta-3	15	2	0	17
Gamma-aminobutyric acid receptor subunit beta-2	15	2	0	17
TAR DNA-binding protein 43	8	0	0	8
G-protein coupled bile acid receptor 1	0	0	3	3
GABA theta subunit	15	2	0	17
Gamma-aminobutyric acid receptor subunit epsilon	15	2	0	17
ATAD5 protein, partial	8	0	0	8
USP1 protein, partial	16	0	0	16
nuclear receptor subfamily 1, group I, member 3	18	0	0	18
67.9K protein	5	0	0	5
chromobox protein homolog 1	15	0	0	15
thyroid hormone receptor beta isoform a	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 2	11	0	0	11
geminin	28	0	0	28
ATP-binding cassette sub-family C member 3	0	23	0	23
Multidrug resistance-associated protein 4	0	23	0	23
Bile salt export pump	0	38	0	38
Cytochrome P450 2J2	0	4	0	4
Nicotinate phosphoribosyltransferase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	24	0	25
Chain A, Hyaluronidase, phage associated	0	1	0	1
cytochrome P450 family 3 subfamily A polypeptide 4	19	0	0	19
IDH1	10	0	0	10
thyroid hormone receptor beta isoform 2	23	0	0	23
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
lethal factor (plasmid)	11	0	0	11
Polyphenol oxidase 2	0	8	0	10
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	1	0	1
Urease	0	3	0	4
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	3	0	3
Alpha-2B adrenergic receptor	0	2	1	3
Spike glycoprotein	7	0	0	7
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	10	0	0	10
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
Chain A, Ferritin light chain	4	0	0	4
thioredoxin reductase	15	0	0	15
SMAD family member 2	10	0	0	10
Fumarate hydratase	5	0	0	5
SMAD family member 3	10	0	0	10
EWS/FLI fusion protein	12	0	0	12
G	9	0	0	9
polyprotein	5	0	0	5
P53	1	0	0	1
peroxisome proliferator activated receptor gamma	15	0	0	15
arylsulfatase A	6	0	0	6
aryl hydrocarbon receptor	18	0	0	18
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	17	0	0	17
thyroid stimulating hormone receptor	11	0	0	11
activating transcription factor 6	10	0	0	10
Histone H2A.x	11	0	0	11
Bloom syndrome protein isoform 1	6	0	0	6
peripheral myelin protein 22 isoform 1	4	0	0	4
hemoglobin subunit beta	3	0	0	3
cellular tumor antigen p53 isoform a	3	0	0	3
heat shock protein beta-1	7	0	0	7
DNA polymerase iota isoform a (long)	10	0	0	10
survival motor neuron protein isoform d	7	0	0	7
cytochrome P450 3A4 isoform 1	15	0	0	15
M-phase phosphoprotein 8	6	0	0	6
muscleblind-like protein 1 isoform 1	8	0	0	8
muscarinic acetylcholine receptor M1	8	0	0	8
Bile salt export pump	0	13	0	13
Interferon beta	15	0	0	15
HLA class I histocompatibility antigen, B alpha chain	9	0	0	9
Cellular tumor antigen p53	18	0	0	18
Inositol hexakisphosphate kinase 1	9	0	0	9
ATPase family AAA domain-containing protein 5	7	0	0	7
Ataxin-2	8	0	0	8
Protein-arginine deiminase type-4	0	6	0	6
cytochrome P450 2C9, partial	9	0	0	9
pregnane X receptor	5	0	0	5
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	12	2	19
Glycine receptor subunit alpha-1	0	12	0	12
Glycine receptor subunit beta	0	12	0	12
Glycine receptor subunit alpha-2	0	12	0	12
Glycine receptor subunit alpha-3	0	12	0	12
ORF73	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	9	0	0	9
aldehyde dehydrogenase 1 family, member A1	24	0	0	24
DNA polymerase kappa isoform 1	6	0	0	6
caspase-1 isoform alpha precursor	2	0	0	2
Caspase-7	3	0	0	3
Inositol monophosphatase 1	3	0	0	3
Solute carrier organic anion transporter family member 1B3	0	5	0	7
Solute carrier organic anion transporter family member 1B1	0	8	0	10
Beta-2 adrenergic receptor	0	1	1	2
Beta-1 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	1	0	1
Chain A, PAPAIN	1	0	0	1
Luciferase	8	0	0	8
15-lipoxygenase, partial	4	0	0	4
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
thyroid stimulating hormone receptor	16	0	0	16
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
histone deacetylase 9 isoform 3	2	0	0	2
nuclear receptor ROR-gamma isoform 1	7	0	0	7
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Histamine H2 receptor	7	0	0	7
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Carbonic anhydrase 4	0	3	0	4
Carbonic anhydrase	0	3	0	4
Carbonic anhydrase 15	0	2	0	3
endonuclease IV	3	0	0	3
dopamine D1 receptor	3	0	0	3
regulator of G-protein signaling 4	6	0	0	6
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
flap endonuclease 1	7	0	0	7
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	4	0	4
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
Chain A, N-methyl-D-aspartate Receptor Subunit 1	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
cytochrome P450 2C9 precursor	3	0	0	3
mitogen-activated protein kinase 1	8	0	0	8
Glutamate receptor ionotropic, NMDA 1	0	1	1	3
Glutamate receptor ionotropic, NMDA 2A	0	1	1	3
Glutamate receptor ionotropic, NMDA 2B	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	1	3
D-alanine--D-alanine ligase	0	1	0	1
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	1	1	3
Proton-coupled amino acid transporter 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 3B	0	1	1	3
Glutamate receptor ionotropic, NMDA 3A	0	1	1	3
ATP-dependent phosphofructokinase	7	0	0	7
importin subunit beta-1 isoform 1	4	0	0	4
snurportin-1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
cytochrome P450 2D6	8	0	0	8
Beta-glucuronidase	0	1	0	1
Beta-glucuronidase	0	1	0	1
Alpha-synuclein	3	2	0	5
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	0	1	1
Cereblon isoform 4	0	2	0	2
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
Protein cereblon	0	4	0	4
Eyes absent homolog 2	0	1	0	1
Amyloid-beta precursor protein	0	3	0	3
Angiotensin-converting enzyme	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Chain A, Beta-lactamase	9	0	0	9
Chain A, JmjC domain-containing histone demethylation protein 3A	5	0	0	5
glp-1 receptor, partial	7	0	0	7
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	8	0	0	8
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	4	0	0	4
5-hydroxytryptamine receptor 4	0	4	0	4
Epidermal growth factor receptor	0	1	0	1
Estrogen receptor	0	6	0	6
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	3	0	3
Muscarinic acetylcholine receptor M5	0	3	0	3
Alpha-2A adrenergic receptor	0	4	0	4
Adenosine receptor A3	0	2	0	2
Muscarinic acetylcholine receptor M1	0	3	0	3
Alpha-1B adrenergic receptor	0	3	0	3
Alpha-2C adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M3	0	3	0	3
Substance-K receptor	0	4	0	4
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
5-hydroxytryptamine receptor 2A	0	5	0	5
5-hydroxytryptamine receptor 2C	0	4	0	4
C-8 sterol isomerase	0	1	0	1
D(3) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 2B	0	4	0	4
Alpha-1A adrenergic receptor	0	3	0	3
5-hydroxytryptamine receptor 6	0	4	0	4
Sodium-dependent dopamine transporter	0	2	0	2
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	2	0	6
Pantothenate synthetase	0	2	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
DNA polymerase beta	3	0	0	3
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	1	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Guanine nucleotide-binding protein G	1	0	0	1
GALC protein	2	0	0	2
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, PROTEIN (PROTEASE)	0	1	0	1
Chain B, PROTEIN (PROTEASE)	0	1	0	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, HIV-II PROTEASE	0	1	0	1
Chain B, HIV-II PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, POL polyprotein	0	0	1	1
Chain B, POL polyprotein	0	0	1	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, protease RETROPEPSIN	0	1	0	1
Chain B, protease RETROPEPSIN	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, HIV-1 protease	0	1	0	1
Chain B, HIV-1 protease	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Pol polyprotein	0	1	0	1
Chain B, Pol polyprotein	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Chain A, Hiv-1 Protease	0	1	0	1
Chain B, Hiv-1 Protease	0	1	0	1
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 1	0	4	0	4
Solute carrier family 22 member 3	0	1	0	1
Albumin	0	0	4	6
Gag-Pol polyprotein	0	2	0	2
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
ATP-dependent translocase ABCB1	0	5	1	13
Replicase polyprotein 1ab	0	2	0	2
Replicase polyprotein 1ab	0	3	0	3
Gag-Pol polyprotein	0	2	0	2
Alpha-1D adrenergic receptor	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Thromboxane-A synthase	0	0	0	1
Genome polyprotein	0	1	0	1
Solute carrier family 22 member 1	0	3	0	3
Protease	0	4	2	8
Multidrug and toxin extrusion protein 2	0	1	0	1
Protease	0	2	1	3
Protease	0	1	0	1
Peptidylglycine alpha-amidating monooxygenase	0	0	0	2
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
cytochrome P450 2D6 isoform 1	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	7	0	0	7
N-glycosylase/DNA lyase	0	1	0	1
Myeloperoxidase	0	2	0	2
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	3	0	5
DNA gyrase subunit B	0	3	0	5
Cytochrome P450 2C8	0	2	0	2
Cytochrome P450 2A6	0	1	0	1
Macrophage migration inhibitory factor	0	1	0	1
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	4	0	6
DNA gyrase subunit A	0	4	0	6
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sodium channel protein type 9 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
PPM1D protein	6	0	0	6
huntingtin isoform 2	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	5	0	0	5
Tyrosine-protein kinase ABL1	0	2	0	2
Methionine aminopeptidase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	0	2
Vascular endothelial growth factor receptor 2	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
Calmodulin-domain protein kinase 1	0	1	0	1
nonstructural protein 1	3	0	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Lanosterol 14-alpha demethylase	0	2	0	2
caspase 7, apoptosis-related cysteine protease	3	0	0	3
caspase-3	3	0	0	3
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
Indoleamine 2,3-dioxygenase 1	0	2	0	3
Glycoprotein hormones alpha chain	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
DNA gyrase subunit B	0	1	0	1
DNA topoisomerase 4 subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	3	0	0	3
Neuronal acetylcholine receptor subunit alpha-4	2	0	0	2
Cholesteryl ester transfer protein	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	2	0	0	2
D-amino-acid oxidase	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
Hydroxycarboxylic acid receptor 2	0	2	1	3
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
glucocerebrosidase	2	0	0	2
streptokinase A precursor	0	0	3	3
Estrogen receptor	0	0	2	2
60 kDa chaperonin	0	2	0	2
Estrogen receptor beta	0	0	2	2
10 kDa chaperonin	0	2	0	2
Chain B, Cathepsin B	0	1	0	1
citrate synthase 2, partial	0	0	1	1
MSH	0	0	0	1
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
nonstructural protein 1	0	1	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
heat shock protein 90	0	0	1	1
LAP4	0	0	1	1
RPL19A	0	0	1	1
Caspase-7	1	0	0	1
beta-2 adrenergic receptor	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
caspase-3	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
amino acid transporter AGP1	0	0	1	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
Vif	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	1	0	2
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Bromodomain-containing protein 4	0	1	0	1
Cathepsin B	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Cystathionine gamma-lyase	0	2	0	2
Mu-type opioid receptor	0	3	0	3
Prostaglandin G/H synthase 2	0	2	0	2
Methionine aminopeptidase 2	0	1	0	1
Methionine aminopeptidase 1	0	1	0	1
heat shock protein 90, putative	0	0	0	1
Progesterone receptor	0	4	2	7
STE24	0	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
CAAX prenyl protease	0	0	0	1
Trypsin	0	0	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
WRN	1	0	0	1
Valosin-containing protein	0	1	0	1
apical membrane antigen 1, AMA1	1	0	0	1
transcriptional regulator ERG isoform 3	2	0	0	2
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	1	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
DNA polymerase eta isoform 1	2	0	0	2
eukaryotic translation initiation factor 4E isoform 1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
phosphoglycerate kinase	1	0	0	1
Solute carrier family 22 member 6	0	0	0	1
Multidrug resistance-associated protein 1	0	2	1	5
Solute carrier family 22 member 6	0	2	0	3
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Solute carrier family 22 member 6	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 8	0	1	0	2
Succinyl-diaminopimelate desuccinylase	0	2	0	2
cytochrome P450 2C19 precursor	2	0	0	2
Chain A, PROTEIN (CATECHOL OXIDASE)	0	1	0	1
Integrin beta-3	1	0	0	1
Integrin alpha-IIb	1	0	0	1
Tyrosinase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
neuropeptide S receptor isoform A	2	0	0	2
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
Pyridoxal kinase	0	0	0	1
Thrombopoietin	1	0	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
ATP-dependent translocase ABCB1	0	2	0	2
Quinolone resistance protein NorA	0	1	0	2
DNA topoisomerase 1	0	1	0	1
ATP-dependent translocase ABCB1	0	2	0	3
Mu-type opioid receptor	0	2	0	2
Chromaffin granule amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	1	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Solute carrier organic anion transporter family member 2B1	0	3	0	3
NH(3)-dependent NAD(+) synthetase	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Cytochrome P450 2B6	0	0	1	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	2	0	2
10 kDa heat shock protein, mitochondrial	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
B-cell lymphoma 6 protein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	2
Carbonic anhydrase 9	0	1	0	2
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	2
alpha-galactosidase	1	0	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
Peroxisome proliferator-activated receptor alpha	1	0	0	1
exodeoxyribonuclease V subunit RecD	0	2	0	2
exodeoxyribonuclease V subunit RecB	0	2	0	2
exodeoxyribonuclease V subunit RecC	0	2	0	2
ATP-dependent 6-phosphofructokinase	0	1	0	1
Dihydropteroate synthase	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Endothelin-1 receptor	0	1	0	1
Hematopoietic prostaglandin D synthase	0	1	0	1
Hydrolase, alpha/beta hydrolase fold family	0	1	0	1
isocitrate dehydrogenase 1, partial	1	0	0	1
serine-protein kinase ATM isoform a	1	0	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Urease subunit alpha	0	2	0	2
D(3) dopamine receptor	0	1	0	1
Urease subunit alpha	0	1	0	1
Urease subunit beta	0	2	0	2
Urease subunit beta	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
NFKB1 protein, partial	1	0	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	4	0	4
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Carbonic anhydrase 12	0	0	0	1
Plasma kallikrein	0	0	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Carbonic anhydrase 3	0	0	0	1
Stromelysin-1	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Carbonic anhydrase 6	0	0	0	1
Substance-P receptor	0	1	0	1
Carbonic anhydrase 7	0	0	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Carbonic anhydrase	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
SLC16A10 protein	0	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Tryprostatin B synthase	0	0	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Carbonic anhydrase	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Carbonic anhydrase 14	0	0	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, Uracil-DNA Glycosylase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Histamine H2 receptor	0	2	0	2
Delta-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
twin arginine protein translocation system - TatA protein	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (344)

Protein Targets (729)

Tuberculosis, Urogenital

Synonyms(2)

Research Excerpts

Overview

Context

Treatment

Research

Studies (344)

Drugs Studied (125)

Protein Targets (729)