Page last updated: 2024-09-28

Pott Disease

Osteitis or caries of the vertebrae, usually occurring as a complication of tuberculosis of the lungs.

Synonyms(4)

Synonym
Tuberculosis, Spinal
Pott Disease
Pott's Disease
Pott's Paraplegia

Research Excerpts

Overview

ExcerptReference
"The pathogenesis of Pott's disease is not established."( Coates, AR; Fossati, G; Henderson, B; Heron, K; Hunt, JF; Mascagni, P; Meghji, S; Nair, SP; Reddi, K; Roberts, MM; White, PA; Zaliani, A, 1997)
"Spinal tuberculosis is a frequent skeletal involvement in tuberculosis."( Gharbi, A; Kadiri, R; Ousehal, A; Saidi, A; Zamiati, W, 2002)
"Pott's disease is an uncommon extrapulmonary form of tuberculosis."( Kim, DS; Kim, IJ; Kim, SJ; Kim, YK; Seok, JW, 2003)
"Spinal tuberculosis is the commonest form of skeletal tuberculosis."( Kumar, R, 2005)
"Spinal tuberculosis is a global disease, timely diagnosis with clinical, imaging, microbiological, histopathological features and complete course of anti-tubercular treatment along with symptomatic treatment appears to be safe and effective."( Bahubali, VH; Bharath, RD; Divya, A; Kruthika, P; Nandeesh, BN; Shukla, DP; Siddaiah, N; Srinivas, D, 2021)
"Mid-thoracic spinal tuberculosis is prone to kyphotic deformities and neurologic impairment."( Jia, R; Jiang, D; Sun, G; Wang, X; Xu, Z; Zhang, Y, 2023)

Context

ExcerptReference
"As the incidence of Pott disease has decreased so too has the medical awareness of this condition."( Lifeso, RM; Weaver, P, 1984)
"Evidences of spinal tuberculosis have been found in Egyptian mummies and the disease is one of the oldest diseases afflicting humans."( Agarwal, S; Jain, UK, 2004)

Treatment

ExcerptReference
"We have treated 75 cases of spinal tuberculosis with chemotherapy as outpatients."( Kim, I; Moon, MS; Park, YO; Woo, YK, 1987)
"For surgical treatment of spinal tuberculosis, carbon-carbonic implants were used for anterior spondylosis in 29 patients; in 14 of them bone autografts were additionally applied."( Beliakov, MV; Garbuz, AE; Gordeev, SK; Guseva, VN; Kuklin, DV, 2003)

Research

Studies (392)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990149 (38.01)23.3326
1990's57 (14.54)12.5806
2000's64 (16.33)18.1394
2010's81 (20.66)28.8240
2020's41 (10.46)9.53
DrugIndicatedRelationship StrengthStudiesTrials
citric acid, anhydrous0low20
lactic acid0low10
formaldehyde0low10
nickel0low10
niacin0low30
nitrous oxide0low20
phenol0low10
pyrazinamide0low360
pyridoxine0low30
albendazole0low10
alendronate0low10
aspirin0low10
azathioprine0low10
carisoprodol0low10
chlormezanone0low10
ciprofloxacin0low30
clofazimine0low10
diazepam0low10
pentetic acid0medium101
ether0low10
gentamicin0low20
halothane0low10
isoniazid0medium11815
ketamine0low10
ketoconazole0low10
leflunomide0low10
mechlorethamine0low30
nalidixic acid0low10
ofloxacin0low10
aminosalicylic acid0medium257
succinylcholine0low20
mitomycin0low10
prednisolone0low30
prednisone0low40
chloramphenicol0low10
cloxacillin0low10
colchicine0low10
methylprednisolone0low10
meglumine0low20
isoxazoles0low10
aminophylline0low10
ethambutol0medium342
durapatite0low20
vancomycin0low10
streptomycin0medium7113
technetium0low70
titanium0low340
gadolinium0low90
calcium sulfate0medium21
fluorine0low20
poloxalene0low10
trolamine salicylate0low150
acetylacetone0low10
methiodal0low10
gallium citrate0low20
fomesafen0low20
xenon radioisotopes0low10
fluorodeoxyglucose f180low90
6-amino-1-hydroxyhexane-1,1-diphosphonate0low10
acetylisoniazid0low10
oxazolidin-2-one0low20
acryloxide0low20
clarithromycin0low10
fibrinogen0low10
vitamin b 60low10
deoxypyridinoline0low10
methotrexate0low20
levofloxacin0low20
moxifloxacin0low20
ropivacaine0medium11
cortisone0low10
trimethoprim, sulfamethoxazole drug combination0low10
linezolid0medium41
metrizamide0low20
fosfomycin0low10
diclazuril0low10
pyrophosphate0low20
ethionamide0low10
thiopental0low10
17-ketosteroids0low20
vitamin k semiquinone radical0low20
amphotericin b0low40
gallium0low20
nitrofurazone0low10
strontium radioisotopes0low10
oxalates0low10
technetium tc 99m pyrophosphate0low10
gadolinium dtpa0medium121
thioacetazone0low40
technetium tc 99m diphosphonate0low10
technetium tc 99m exametazime0low10
enerbol0low10
clove0low10
cosyntropin0low10
ro13-99040low20
cortisol succinate, sodium salt0low10
glycolipids0low10
chondroitin0low10
calca protein, human0low10
technetium tc 99m medronate0low60
technetium tc-99m tetrofosmin0low10
exudates0low60
rifampin0medium867
rifapentine0low10
trifazid0low10

Protein Targets (770)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Geranylgeranyl pyrophosphate synthase0202
Farnesyl pyrophosphate synthase0404
estrogen nuclear receptor alpha370037
Cocaine esterase0101
Coagulation factor XII0101
Cholinesterase0101
Liver carboxylesterase 10101
Acetylcholinesterase0202
Liver carboxylesterase 10101
Chain A, Beta-lactamase5005
cellular tumor antigen p53 isoform a8008
chromobox protein homolog 1120012
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
Guanine nucleotide-binding protein G1001
Inositol monophosphatase 12002
Luciferase6006
glp-1 receptor, partial4004
hypoxia-inducible factor 1 alpha subunit8008
RAR-related orphan receptor gamma180018
ATAD5 protein, partial7007
Fumarate hydratase6006
TDP1 protein210021
GLI family zinc finger 3180018
AR protein250025
caspase 7, apoptosis-related cysteine protease3003
nuclear receptor subfamily 1, group I, member 3120012
progesterone receptor120012
glucocorticoid receptor [Homo sapiens]220022
retinoic acid nuclear receptor alpha variant 1170017
retinoid X nuclear receptor alpha140014
estrogen-related nuclear receptor alpha190019
farnesoid X nuclear receptor100010
pregnane X nuclear receptor150015
polyprotein6006
67.9K protein6006
peroxisome proliferator activated receptor gamma140014
vitamin D (1,25- dihydroxyvitamin D3) receptor200020
caspase-33003
IDH19009
euchromatic histone-lysine N-methyltransferase 2220022
aryl hydrocarbon receptor100010
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a150015
v-jun sarcoma virus 17 oncogene homolog (avian)100010
nuclear receptor subfamily 1, group I, member 26006
Histone H2A.x7007
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 16006
nuclear factor erythroid 2-related factor 2 isoform 2110011
transcriptional regulator ERG isoform 34004
thyroid hormone receptor beta isoform 2170017
histone deacetylase 9 isoform 32002
heat shock protein beta-16006
mitogen-activated protein kinase 13003
urokinase-type plasminogen activator precursor6006
plasminogen precursor6006
urokinase plasminogen activator surface receptor precursor6006
geminin200020
Vif0001
peripheral myelin protein 22110011
survival motor neuron protein isoform d6006
muscleblind-like protein 1 isoform 16006
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
lamin isoform A-delta10190019
neuropeptide S receptor isoform A3003
ATP-binding cassette sub-family C member 3027027
Multidrug resistance-associated protein 4027028
Voltage-dependent calcium channel gamma-2 subunit100010
Bile salt export pump037037
Interferon beta160016
Cellular tumor antigen p53150015
Integrin beta-35106
Integrin alpha-IIb5106
Methionine aminopeptidase0101
Glutamate receptor 2100010
Fatty-acid amide hydrolase 10303
Canalicular multispecific organic anion transporter 1025025
ATPase family AAA domain-containing protein 5100010
Ataxin-2100010
Chain A, farnesyl pyrophosphate synthase0101
Hypoxanthine-guanine phosphoribosyltransferase0101
Farnesyl pyrophosphate synthase 0101
Farnesyl pyrophosphate synthase 0101
histone acetyltransferase KAT2A isoform 1120012
Aminoglycoside 3'-phosphotransferase 0001
ATP-dependent phosphofructokinase8008
thioredoxin reductase160016
USP1 protein, partial110011
Microtubule-associated protein tau6006
Chain A, 2-oxoglutarate Oxygenase100010
thioredoxin glutathione reductase6006
Smad34004
microphthalmia-associated transcription factor isoform 90101
Carbonic anhydrase 10707
Carbonic anhydrase 20718
Tyrosine-protein phosphatase non-receptor type 10011
Chain A, HADH2 protein9009
Chain B, HADH2 protein9009
Chain A, Cruzipain5005
interleukin 87007
phosphopantetheinyl transferase7007
GLS protein5005
peroxisome proliferator-activated receptor delta150015
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA9009
nuclear factor erythroid 2-related factor 2 isoform 1170017
Cytochrome P450 1A20607
Cytochrome P450 3A4012014
Cytochrome P450 2D60506
Cytochrome P450 2C9 0618
Cytochrome P450 2C190506
Nuclear receptor ROR-gamma7007
Potassium voltage-gated channel subfamily H member 2010113
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20304
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE150015
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
aldehyde dehydrogenase 1 family, member A1140014
thyroid stimulating hormone receptor7007
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 4160016
EWS/FLI fusion protein160016
cytochrome P450 2D6100010
glucocerebrosidase2002
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Bloom syndrome protein isoform 15005
DNA polymerase iota isoform a (long)100010
DNA polymerase kappa isoform 13003
muscarinic acetylcholine receptor M17007
lethal factor (plasmid)3003
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0202
Prostaglandin G/H synthase 2 0202
Epidermal growth factor receptor0101
Fatty acid-binding protein, liver0303
Myeloperoxidase0202
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10202
Adenosine receptor A2a0202
Substance-P receptor0101
Prostaglandin G/H synthase 20303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-176114
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10011
Sigma non-opioid intracellular receptor 10011
Chain A, Ferritin light chain6006
acetylcholinesterase5005
SMAD family member 22002
SMAD family member 32002
G110011
P532002
arylsulfatase A6006
thyroid stimulating hormone receptor5005
activating transcription factor 68008
peripheral myelin protein 22 isoform 15005
hemoglobin subunit beta1001
cytochrome P450 3A4 isoform 17007
M-phase phosphoprotein 85005
Gamma-aminobutyric acid receptor subunit pi75113
Bile salt export pump012012
HLA class I histocompatibility antigen, B alpha chain 110011
Gamma-aminobutyric acid receptor subunit beta-175113
Gamma-aminobutyric acid receptor subunit delta75113
Gamma-aminobutyric acid receptor subunit gamma-275113
Gamma-aminobutyric acid receptor subunit alpha-575113
Gamma-aminobutyric acid receptor subunit alpha-375113
Gamma-aminobutyric acid receptor subunit gamma-175113
Gamma-aminobutyric acid receptor subunit alpha-275113
Gamma-aminobutyric acid receptor subunit alpha-475113
Gamma-aminobutyric acid receptor subunit gamma-375113
Gamma-aminobutyric acid receptor subunit alpha-675113
Gamma-aminobutyric acid receptor subunit beta-375113
Gamma-aminobutyric acid receptor subunit beta-275113
GABA theta subunit75113
Inositol hexakisphosphate kinase 1110011
Gamma-aminobutyric acid receptor subunit epsilon75113
Protein-arginine deiminase type-40505
cytochrome P450 2C9, partial110011
ATP synthase subunit c0011
Replicase polyprotein 1ab0202
Spike glycoprotein100010
ATP synthase subunit c 0101
Sigma intracellular receptor 20202
NFKB1 protein, partial1001
flap endonuclease 16006
ras-related protein Rab-9A3003
Rap guanine nucleotide exchange factor 34004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
streptokinase A precursor0066
Dihydroxyacetone phosphate acyltransferase0001
30S ribosomal protein S60202
30S ribosomal protein S70202
50S ribosomal protein L150202
50S ribosomal protein L100202
50S ribosomal protein L110202
50S ribosomal protein L7/L120202
50S ribosomal protein L190202
50S ribosomal protein L10202
50S ribosomal protein L200202
50S ribosomal protein L270202
50S ribosomal protein L280202
50S ribosomal protein L290202
50S ribosomal protein L310202
50S ribosomal protein L31 type B0202
50S ribosomal protein L320202
50S ribosomal protein L330202
50S ribosomal protein L340202
50S ribosomal protein L350202
50S ribosomal protein L360202
30S ribosomal protein S100202
30S ribosomal protein S110202
30S ribosomal protein S120202
30S ribosomal protein S130202
30S ribosomal protein S160202
30S ribosomal protein S180202
30S ribosomal protein S190202
30S ribosomal protein S200202
30S ribosomal protein S20202
30S ribosomal protein S30202
30S ribosomal protein S40202
30S ribosomal protein S50202
30S ribosomal protein S80202
30S ribosomal protein S90202
50S ribosomal protein L130202
50S ribosomal protein L140202
50S ribosomal protein L160202
50S ribosomal protein L230202
30S ribosomal protein S150202
50S ribosomal protein L170202
50S ribosomal protein L210202
50S ribosomal protein L300202
50S ribosomal protein L60202
30S ribosomal protein S140202
30S ribosomal protein S170202
30S ribosomal protein S10202
50S ribosomal protein L180202
50S ribosomal protein L20202
50S ribosomal protein L30202
50S ribosomal protein L240202
50S ribosomal protein L40202
50S ribosomal protein L220202
50S ribosomal protein L50202
30S ribosomal protein S210202
50S ribosomal protein L250202
50S ribosomal protein L36 20202
Methionine--tRNA ligase, mitochondrial0011
thyroid hormone receptor beta isoform a6006
cytochrome P450 2C9 precursor3003
DNA gyrase subunit B0202
DNA gyrase subunit A0202
DNA gyrase subunit B0203
DNA gyrase subunit A06010
DNA gyrase subunit B06010
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0203
DNA topoisomerase 2-alpha0105
DNA gyrase subunit A0203
Multidrug resistance protein MdtK0011
Histamine H2 receptor5005
DNA gyrase subunit B0608
DNA gyrase subunit A0709
Enoyl-[acyl-carrier-protein] reductase [NADH]0207
DNA topoisomerase 4 subunit A0202
DNA topoisomerase 4 subunit B0202
Integrase 0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, JmjC domain-containing histone demethylation protein 3A4004
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0001
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
importin subunit beta-1 isoform 16006
snurportin-16006
GTP-binding nuclear protein Ran isoform 14004
ATP-dependent translocase ABCB10508
Solute carrier organic anion transporter family member 1B30305
Solute carrier organic anion transporter family member 1B10304
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
cytochrome P450 2D6 isoform 14004
potassium voltage-gated channel subfamily H member 2 isoform d4004
mitogen-activated protein kinase kinase kinase kinase 2 isoform 10011
eyes absent homolog 2 isoform a1001
mitogen-activated protein kinase kinase kinase 3 isoform 10011
Estrogen receptor0022
Spike glycoprotein0011
5-hydroxytryptamine receptor 1A0224
Cruzipain0101
C-terminal-binding protein 11001
Estrogen receptor beta0022
Beta-lactamase 0101
Solute carrier family 22 member 80101
Beta-lactamase OXA-70001
Solute carrier family 15 member 10101
Beta-lactamase TEM0101
Solute carrier family 15 member 20101
Efflux transporter 0101
Beta-lactamase 0101
Solute carrier family 15 member 20101
Metallo-b-lactamase 0001
Beta-lactamase class B VIM-2 0001
endonuclease IV3003
PAX80001
pregnane X receptor3003
PPM1D protein4004
Thrombopoietin2002
estrogen receptor 2 (ER beta)9009
nuclear receptor subfamily 0 group B member 10101
cytochrome P450 2C19 precursor3003
atrial natriuretic peptide receptor 2 precursor1001
steroidogenic factor 10101
caspase-1 isoform alpha precursor2002
Solute carrier family 22 member 30101
Tubulin alpha-1A chain0213
Tubulin beta chain0213
Plasma kallikrein0001
Tubulin beta-4A chain0326
ATP-dependent translocase ABCB10303
Tubulin beta chain0326
Tubulin alpha-3C chain0326
Serine/threonine-protein kinase pim-10101
ATP-dependent translocase ABCB10303
Tubulin alpha-1B chain0326
Tubulin alpha-4A chain0326
Tubulin beta-4B chain0326
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain0326
Tubulin beta-2A chain0326
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain0326
Tubulin beta-2B chain0202
Tubulin alpha-3E chain0326
Tubulin alpha-1A chain0326
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
CREB-binding protein1001
Tubulin alpha-1C chain0326
Tubulin beta-6 chain0326
Tubulin beta-2B chain0326
Tubulin beta-1 chain0326
nuclear receptor ROR-gamma isoform 17007
dopamine D1 receptor3003
regulator of G-protein signaling 41001
atrial natriuretic peptide receptor 1 precursor1001
Glucocorticoid receptor08215
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10808
Corticosteroid-binding globulin0202
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 432002
Multidrug and toxin extrusion protein 10303
Gamma-aminobutyric acid 0101
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Alpha-1-acid glycoprotein 10001
Albumin0146
Albumin0011
Gamma-aminobutyric acid receptor subunit alpha-10203
Gamma-aminobutyric acid receptor subunit beta-10203
Neuronal acetylcholine receptor subunit alpha-41102
Gamma-aminobutyric acid receptor subunit alpha-20203
Gamma-aminobutyric acid receptor subunit alpha-30203
Neuronal acetylcholine receptor subunit beta-21102
Gamma-aminobutyric acid receptor subunit alpha-10235
Translocator protein0214
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit gamma-20224
Gamma-aminobutyric acid receptor subunit alpha-40203
Gamma-aminobutyric acid receptor subunit gamma-20203
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30213
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50224
Gamma-aminobutyric acid receptor subunit alpha-30213
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit beta-20224
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Neuronal acetylcholine receptor subunit alpha-70101
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Gamma-aminobutyric acid receptor subunit alpha-60202
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit pi0101
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0202
Nuclear receptor subfamily 1 group I member 20033
Polymerase acidic protein0011
Nuclear receptor subfamily 1 group I member 20022
Pantothenate synthetase0202
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
DNA polymerase beta3003
Polyphenol oxidase 20305
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
UDP-N-acetylglucosamine 1-carboxyvinyltransferase0101
Amine oxidase [flavin-containing] B0202
Amine oxidase [flavin-containing] A 0101
Amine oxidase [flavin-containing] A0404
Amine oxidase [flavin-containing] B0202
C-X-C chemokine receptor type 30101
bromodomain adjacent to zinc finger domain 2B5005
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
N-glycosylase/DNA lyase0101
Formamidopyrimidine-DNA glycosylase0101
Cytochrome P450 2C80202
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Endonuclease III-like protein 10101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
Glutamate receptor ionotropic, NMDA 2D0101
Acetylcholinesterase0101
Glutamate receptor ionotropic, NMDA 3B0101
Glutamate receptor ionotropic, NMDA 1 0202
Sodium channel protein type 4 subunit alpha0101
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 2A 0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0202
Glutamate receptor ionotropic, NMDA 3A0202
Estrogen receptor beta0101
Solute carrier family 22 member 1 0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Chymotrypsinogen A0101
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0202
Epoxide hydrolase 10001
Aldo-keto reductase family 1 member B10404
Muscarinic acetylcholine receptor M20202
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Alpha-2A adrenergic receptor0303
Aromatase0202
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Polyunsaturated fatty acid lipoxygenase ALOX150202
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
5-hydroxytryptamine receptor 2A0202
Indoleamine 2,3-dioxygenase 10202
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0202
Cytochrome P450 11B1, mitochondrial0101
Alpha-2B adrenergic receptor0202
Cytochrome P450 7A1 0101
Cytochrome P450 11B2, mitochondrial0101
Estrogen receptor0101
Substance-K receptor0202
UDP-glucuronosyltransferase 1A1 0101
Sodium-dependent noradrenaline transporter 0404
Thromboxane-A synthase 0101
Histamine H2 receptor0202
Gonadotropin-releasing hormone receptor0112
Sodium-dependent serotonin transporter0202
Type-1 angiotensin II receptor0101
Malate dehydrogenase, cytoplasmic0101
Delta-type opioid receptor0202
Cytochrome P450 4F20101
Sodium-dependent dopamine transporter 0404
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Lanosterol 14-alpha demethylase0314
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
matrix metalloproteinase 1, partial0011
nonstructural protein 14004
Parkin1001
pyruvate kinase1001
NPC intracellular cholesterol transporter 1 precursor1001
huntingtin isoform 21001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Endothelin receptor type B1001
Endothelin-1 receptor1001
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Dihydroorotate dehydrogenase (quinone), mitochondrial0101
Replicase polyprotein 1ab0101
CAAX prenyl protease 2 isoform 20001
DNA primase0101
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial0101
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Renin0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
15-lipoxygenase, partial3003
Thymidylate synthase 0101
alpha-galactosidase2002
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Androgen receptor0303
Voltage-dependent L-type calcium channel subunit alpha-1C0101
DNA gyrase subunit B0101
Replicase polyprotein 1ab0101
Potassium voltage-gated channel subfamily E member 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Potassium voltage-gated channel subfamily KQT member 10101
Sodium channel protein type 5 subunit alpha0101
Caspase-71001
caspase-31001
Pyruvate kinase PKM0101
thyrotropin-releasing hormone receptor1001
lysosomal alpha-glucosidase preproprotein1001
Amyloid-beta precursor protein0101
Cholesteryl ester transfer protein0101
D-amino-acid oxidase0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Metabotropic glutamate receptor 50101
Snake venom metalloproteinase BaP10101
NAD(+) hydrolase SARM10202
STE240001
CAAX prenyl protease0001
Trypsin0001
Vpr1001
Rap guanine nucleotide exchange factor 41001
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
GALC protein1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Carbonic anhydrase 120101
Endolysin0011
Carbonic anhydrase 30101
Sulfotransferase 1A1 0001
Cannabinoid receptor 10101
Carbonic anhydrase 40101
Carbonic anhydrase 60202
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 70101
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 90101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Carbonic anhydrase 30202
Carbonic anhydrase0101
Carbonic anhydrase 130101
Carbonic anhydrase 150101
Carbonic anhydrase 130101
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
NAD-dependent protein deacetylase sirtuin-60101
Pyridoxal kinase0001
Chain A, dATP pyrophosphohydrolase0101
Chain A, Adenylate cyclase type 50101
Chain B, Adenylate cyclase type 20101
Carbonic anhydrase0101
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 1A40101
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
60 kDa heat shock protein, mitochondrial0202
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Caspase-10101
Alpha-synuclein0101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
10 kDa heat shock protein, mitochondrial0202
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Potassium channel subfamily K member 30101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
D(1A) dopamine receptor1001
Acetylcholinesterase0101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Alpha-1B adrenergic receptor0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0101
Sodium-dependent serotonin transporter0101
Alpha-1A adrenergic receptor0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]