| Assay ID | Title | Year | Journal | Article |
|---|
| AID515292 | Antibacterial activity against Staphylococcus aureus MTCC 96 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID600599 | Inhibition of IKK-beta in human OCI-LY10 cells assessed as decrease in renilla values at 2.5 to 10 ug/ml after 10 hrs by IkB-photinus/Renilla assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa. |
| AID600602 | Inhibition of IKK-beta in human OCI-LY19 cells assessed as decrease in renilla values at 10 ug/ml after 10 hrs by IkB-photinus/Renilla assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa. |
| AID515298 | Antifungal activity against Aspergillus niger MTCC 1344 at 30 ug/ml after 24 to 96 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID1075967 | Cytotoxicity against estrogen receptor-negative human MDA-MB-231 cells assessed as cell viability after 72 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID1075946 | Reduction in HDAC-8 nuclear expression in estrogen receptor-negative human MDA-MB-231 cells at 2 uM after 24 hrs by Western blotting analysis | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID1075960 | Cell cycle arrest in estrogen receptor-negative human MDA-MB-231 cells assessed as decrease in Cyclin E expression at 2 uM after 24 hrs by Western blotting analysis | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID515297 | Antifungal activity against Rhizopus oryzae MTCC 262 at 30 ug/ml after 24 to 96 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID1075962 | Cell cycle arrest in estrogen receptor-negative human MDA-MB-231 cells assessed as accumulation at S phase at 2 uM after 24 hrs by Propidium iodide staining-based flow cytometric analysis (Rvb = 19 +/- 1%) | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID600597 | Induction of IkappaB in human OCI-LY3 cells assessed as fold increase in luciferase reporter gene | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa. |
| AID1075959 | Cell cycle arrest in estrogen receptor-negative human MDA-MB-231 cells assessed as decrease in CDK2 expression at 2 uM after 24 hrs by Western blotting analysis | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID515300 | Antifungal activity against Saccharomyces cerevisiae MTCC 171 at 30 ug/ml after 24 to 96 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID1075948 | Reduction in HDAC-3 nuclear expression in estrogen receptor-negative human MDA-MB-231 cells at 2 uM after 24 hrs by Western blotting analysis | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID1075947 | Inhibition of NFkappaB activity in estrogen receptor-negative human MDA-MB-231 cells assessed as retention of NFKappaB/Rel A in cytoplasm at 2 uM after 24 hrs by DAPI/PI staining-based confocal microscopy | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID515303 | Antifungal activity against Candida albicans MTCC 227 at 100 ug/ml after 24 to 96 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID1075964 | Inhibition of NFkappaB activity in estrogen receptor-positive human MCF7 cells at 2 uM after 24 hrs by SEAP reporter assay | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID1075955 | Effect on p21 gene expression in estrogen receptor-negative human MDA-MB-231 cells at 2 uM after 24 hrs by luciferase reporter gene assay | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID515296 | Antibacterial activity against Klebsiella pneumoniae MTCC 39 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID600601 | Inhibition of IKK-beta in human OCI-LY19 cells assessed as decrease in renilla values at 10 ug/ml after 2.5 to 10 hrs by IkB-photinus/Renilla assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa. |
| AID600598 | Induction of IkappaB in human OCI-LY3 cells assessed as fold increase in luciferase reporter gene after 10 hrs | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa. |
| AID1075965 | Inhibition of NFkappaB activity in estrogen receptor-negative human MDA-MB-231 cells at 2 uM after 24 hrs by SEAP reporter assay | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID515302 | Antifungal activity against Aspergillus niger MTCC 1344 at 100 ug/ml after 24 to 96 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID515301 | Antifungal activity against Rhizopus oryzae MTCC 262 at 100 ug/ml after 24 to 96 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID600600 | Inhibition of IKK-beta in human OCI-LY3 cells assessed as decrease in renilla values at 2.5 to 5 ug/ml after 10 hrs by IkB-photinus/Renilla assay | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa. |
| AID1075963 | Cell cycle arrest in estrogen receptor-negative human MDA-MB-231 cells assessed as accumulation at G1 phase at 2 uM after 24 hrs by Propidium iodide staining-based flow cytometric analysis (Rvb = 54.66 +/- 2.51%) | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID515304 | Antifungal activity against Saccharomyces cerevisiae MTCC 171 at 100 ug/ml after 24 to 96 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID1075966 | Cytotoxicity against estrogen receptor-positive human MCF7 cells assessed as cell viability after 72 hrs by MTT assay | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID1075958 | Induction of apoptosis in estrogen receptor-negative human MDA-MB-231 cells assessed as increase in PARP cleavage at 2 uM after 24 hrs by Western blotting analysis | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID1075961 | Cell cycle arrest in estrogen receptor-negative human MDA-MB-231 cells assessed as accumulation at G2/M phase at 2 uM after 24 hrs by Propidium iodide staining-based flow cytometric analysis (Rvb = 26.33 +/- 3.05%) | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID1075956 | Induction of apoptosis in estrogen receptor-negative human MDA-MB-231 cells assessed as reduced procaspase-3 level at 2 uM after 24 hrs by Western blotting analysis | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID515293 | Antibacterial activity against Staphylococcus epidermidis MTCC 437 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID600595 | Induction of IkappaB in human OCI-LY3 cells assessed as fold increase in luciferase reporter gene at 11 uM | 2009 | Journal of natural products, Mar-27, Volume: 72, Issue:3
| Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa. |
| AID515294 | Antibacterial activity against Escherichia coli MTCC 443 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID515299 | Antifungal activity against Candida albicans MTCC 227 at 30 ug/ml after 24 to 96 hrs by agar cup diffusion method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID515295 | Antibacterial activity against Pseudomonas aeruginosa MTCC 741 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| AID1075957 | Induction of apoptosis in estrogen receptor-negative human MDA-MB-231 cells assessed as increase in Rb cleavage at 2 uM after 24 hrs by Western blotting analysis | 2014 | Bioorganic & medicinal chemistry letters, Mar-01, Volume: 24, Issue:5
| Rugulactone derivatives act as inhibitors of NF-κB activation and modulates the transcription of NF-κB dependent genes in MDA-MB-231cells. |
| AID515291 | Antibacterial activity against Bacillus subtilis MTCC 441 by broth dilution method | 2010 | European journal of medicinal chemistry, Oct, Volume: 45, Issue:10
| Stereoselective synthesis and biological evaluation of (R)-rugulactone, (6R)-((4R)-hydroxy-6-phenyl-hex-2-enyl)-5,6-dihydro-pyran-2-one and its 4S epimer. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |