Actinobacillosis

A disease characterized by suppurative and granulomatous lesions in the respiratory tract, upper alimentary tract, skin, kidneys, joints, and other tissues. Actinobacillus lignieresii infects cattle and sheep while A. equuli infects horses and pigs.

Synonyms(1)

Synonym
Actinobacillosis

Research

Studies (6)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	3 (50.00)	23.3326
1990's	1 (16.67)	12.5806
2000's	2 (33.33)	18.1394
2010's	0 (0.00)	28.8240
2020's	0 (0.00)	9.53

Drug	Relationship Strength	Studies
sodium iodide	low	1
streptomycin	low	1
trolamine salicylate	low	1
trimethoprim, sulfamethoxazole drug combination	low	1
sulfur	low	1
rifampin	low	1

Protein Targets (59)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Cruzipain	1	0	0	1
interleukin 8	1	0	0	1
15-lipoxygenase, partial	1	0	0	1
Microtubule-associated protein tau	1	0	0	1
AR protein	1	0	0	1
aldehyde dehydrogenase 1 family, member A1	2	0	0	2
thyroid stimulating hormone receptor	1	0	0	1
glucocorticoid receptor [Homo sapiens]	2	0	0	2
retinoid X nuclear receptor alpha	2	0	0	2
pregnane X nuclear receptor	2	0	0	2
estrogen nuclear receptor alpha	1	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
peroxisome proliferator-activated receptor delta	1	0	0	1
peroxisome proliferator activated receptor gamma	1	0	0	1
vitamin D (1,25- dihydroxyvitamin D3) receptor	2	0	0	2
euchromatic histone-lysine N-methyltransferase 2	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
ATP-binding cassette sub-family C member 3	0	1	0	1
Multidrug resistance-associated protein 4	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Bile salt export pump	0	3	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Bile salt export pump	0	2	0	2
Albumin	0	0	1	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Cytochrome P450 2B6	0	0	1	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Alpha-synuclein	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Histamine H2 receptor	1	0	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	2	0	3
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
vitamin D3 receptor isoform VDRA	1	0	0	1
Protein-arginine deiminase type-4	0	2	0	2
RAR-related orphan receptor gamma	1	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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Actinobacillosis

Synonyms(1)

Research

Studies (6)

Drugs Studied (8)

Protein Targets (59)