Diaphragmatic Paralysis

Complete or severe weakness of the muscles of respiration. This condition may be associated with MOTOR NEURON DISEASES; PERIPHERAL NERVE DISEASES; NEUROMUSCULAR JUNCTION DISEASES; SPINAL CORD DISEASES; injury to the PHRENIC NERVE; and other disorders.

Synonym
Diaphragmatic Paralysis
Paralysis, Respiratory Muscle
Respiratory Paralysis

Excerpt	Reference
"Diaphragmatic paralysis is commonly caused by surgical and traumatic injuries, malignant neoplasm, and neurodegenerative disorders."	( Dambara, T; Isonuma, H; Kikuchi, Y; Naito, T; Ohshima, H; Oike, M; Otsuki, Y; Sakamoto, N; Tsukada, M; Yokokawa, H, 2012)
"Hemidiaphragmatic paralysis is the most common adverse effect associated with interscalene block."	( Awoniyi, CA; Chiaghana, CO, 2016)

Excerpt	Reference
"Bulbar and respiratory paralysis developed in one patient and required prolonged ventilation therapy; the other patient had peripheral muscular and unilateral facial weakness, with notable pleocytosis was present in both."	( SMith, WR; Wilson, AF, 1975)
"Prolonged postoperative neuromuscular respiratory paralysis after administration of a nondepolarizing neuromuscular blocking agent is a serious concern during anesthetic management of patients with Charcot-Marie-Tooth disease (CMTD)."	( Hiramatsu, S; Moriwaki, K; Nakao, M; Tsutsumi, YM, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	161 (47.08)	23.3326
1990's	56 (16.37)	12.5806
2000's	67 (19.59)	18.1394
2010's	51 (14.91)	28.8240
2020's	7 (2.05)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	3	0
ethylene glycol	low	1	0
acetone	low	1	0
carbon monoxide	low	1	0
choline	low	2	0
chlorine	low	1	0
hydrochloric acid	low	1	0
salicylic acid	low	1	0
hydrogen sulfide	low	1	0
lactic acid	low	1	0
dimethyl sulfoxide	low	1	0
hydrogen carbonate	low	3	0
hydrogen	low	1	0
nitrates	low	1	0
nitrous oxide	low	3	0
parathion	low	3	0
pyruvic acid	low	1	0
uric acid	low	1	0
8-hydroxy-2-(di-n-propylamino)tetralin	low	1	0
1,3-dipropyl-8-cyclopentylxanthine	low	2	0
4-aminopyridine	low	1	0
phenytoin	low	1	0
theophylline	low	3	0
amiodarone	low	1	0
amitriptyline	low	1	0
anastrozole	low	1	0
aspirin	low	1	0
azathioprine	low	1	0
aztreonam	low	1	0
baclofen	low	2	0
bupivacaine	medium	12	2
caffeine	low	1	0
chlordiazepoxide	low	1	0
chlorpromazine	low	2	0
clebopride	low	1	0
clonidine	low	1	0
cypermethrin	low	1	0
cyproheptadine	low	1	0
diazepam	low	1	0
dibucaine	low	1	0
pentetic acid	low	1	0
dimethoate	low	4	0
valproic acid	low	1	0
doxapram	low	1	0
edrophonium	low	1	0
enflurane	low	1	0
brl 42810	low	1	0
fentanyl	low	2	0
fenthion	low	1	0
fluphenazine	low	1	0
fluoxetine	low	2	0
furosemide	low	1	0
gentamicin	low	2	0
guaifenesin	low	1	0
guanidine	low	1	0
halothane	low	5	0
hexobarbital	low	1	0
lidocaine	medium	11	1
imipramine	low	1	0
isoproterenol	low	2	0
ketorolac	low	1	0
malathion	low	4	0
mepivacaine	medium	5	1
metaproterenol	low	1	0
methadone	low	1	0
methamidophos	low	1	0
methomyl	low	1	0
methyl parathion	low	1	0
midazolam	low	2	0
apnea	low	14	0
neostigmine	low	14	0
pentobarbital	low	4	0
pentoxifylline	low	1	0
procainamide	low	2	0
procaine	low	3	0
propofol	low	1	0
riluzole	low	1	0
succinylcholine	low	12	0
tetracaine	medium	1	1
krypton	low	3	0
thalidomide	low	1	0
nikethamide	low	1	0
tolmetin	low	1	0
triazolam	low	1	0
trimeprazine	low	1	0
urethane	low	1	0
prednisolone	low	5	0
thymidine	low	1	0
hydroxyproline	low	1	0
trichlorfon	low	2	0
prednisone	low	2	0
pentylenetetrazole	low	2	0
amifampridine	low	1	0
isoflurophate	low	1	0
physostigmine	low	1	0
tubocurarine	low	2	0
aminopyrine	low	1	0
uridine diphosphate	low	1	0
kanamycin a	low	2	0
edetic acid	low	4	0
gallamine triethiodide	low	6	0
barbituric acid	low	1	0
chloroform	low	1	0
mannitol	low	2	0
valine	low	1	0
triamcinolone acetonide	low	1	0
phencyclidine	low	1	0
cyclizine	low	4	0
methylprednisolone	low	3	0
soman	low	1	0
sarin	low	1	0
cyclohexanol	low	1	0
obidoxime chloride	low	2	0
ambenonium chloride	low	1	0
framycetin	low	2	0
yohimbine	low	1	0
pyrazines	low	2	0
paraoxon	low	2	0
aminophylline	low	2	0
2-aminopurine	low	1	0
2,3-diaminopyridine	low	1	0
coniine	low	1	0
limestone	low	1	0
fusarium	low	1	0
alpha-aminopyridine	low	1	0
copper gluconate	low	1	0
dimethoxon	low	2	0
sulfur hexafluoride	low	1	0
streptomycin	low	4	0
carbonates	low	1	0
trimethaphan	low	1	0
mercury	low	1	0
neon	low	1	0
helium	low	2	0
magnesium sulfate	low	1	0
barium sulfate	low	1	0
methyl demeton	low	1	0
barium nitrate	low	1	0
trolamine salicylate	low	1	0
tiletamine hydrochloride	low	1	0
fluorides	low	1	0
phenyl acetate	low	1	0
4-methoxyamphetamine	low	1	0
glutamic acid	low	2	0
tramadol	low	1	0
emepronium	low	1	0
gallium citrate	low	1	0
vecuronium bromide	low	7	0
sufentanil	low	1	0
captopril	low	1	0
atracurium	medium	3	1
fomesafen	low	10	0
adenosine	low	1	0
cisatracurium	medium	1	1
triazoles	low	1	0
zoledronic acid	low	1	0
methotrimeprazine	low	1	0
nicotine	low	1	0
levobupivacaine	medium	4	2
nimbolide	low	1	0
nitisinone	low	1	0
alphaprodine	low	1	0
xaliproden	low	1	0
omega-n-methylarginine	low	1	0
proline	low	1	0
technetium tc 99m pentetate	low	1	0
atropine	low	10	0
ropivacaine	medium	7	5
colistimethate sodium	low	1	0
bortezomib	low	1	0
glycogen	low	1	0
inositol 3-phosphate	low	1	0
pancuronium	medium	8	1
rocuronium	medium	6	1
phosphoramidon	low	1	0
melphalan	low	1	0
thiosemicarbazide	low	1	0
thiopental	low	1	0
quinine	low	1	0
2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine	low	1	0
bilirubin	low	1	0
mivacurium	low	2	0
phenylephrine hydrochloride	medium	7	1
hydromorphone	low	2	0
naloxone	low	4	0
morphine	medium	5	1
lead	low	1	0
barium	low	5	0
levallorphan	low	1	0
gallium	low	1	0
monocrotophos	low	1	0
veratrine	low	1	0
heroin	low	1	0
pregabalin	low	1	0
tetrodotoxin	low	8	0
radium	low	2	0
g(m1) ganglioside	low	1	0
ro13-9904	low	1	0
picrotoxin	low	1	0
cardiovascular agents	low	1	0
piperidines	low	1	0
colistin	low	4	0
warfarin	low	3	0
bromfenacoum	low	1	0
saxitoxin	low	1	0
pyrethrins	low	1	0
vitamin b 12	low	1	0
acyclovir	low	4	0
cyclic gmp	low	1	0
valacyclovir	low	1	0
pralidoxime	medium	6	1
gq1b ganglioside	low	1	0

Protein Targets (1,280)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
thioredoxin reductase	36	0	0	36
ATAD5 protein, partial	12	0	0	12
TDP1 protein	41	0	0	41
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	10	0	0	10
thyroid stimulating hormone receptor	18	0	0	18
estrogen-related nuclear receptor alpha	44	0	0	44
67.9K protein	5	0	0	5
euchromatic histone-lysine N-methyltransferase 2	54	0	0	54
peripheral myelin protein 22 isoform 1	7	0	0	7
chromobox protein homolog 1	23	0	0	23
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
DNA polymerase iota isoform a (long)	5	0	0	5
nuclear receptor ROR-gamma isoform 1	13	0	0	13
geminin	38	0	0	38
muscarinic acetylcholine receptor M1	21	0	0	21
lamin isoform A-delta10	40	0	0	40
5-hydroxytryptamine receptor 1A	0	7	1	9
Adenosine receptor A3	0	10	3	14
Adenosine receptor A1	0	9	3	15
Adenosine receptor A1	0	3	0	3
Adenosine receptor A3	0	6	0	6
Adenosine receptor A2a	0	9	8	21
Adenosine receptor A2b	0	6	3	12
Adenosine receptor A2b	0	6	2	13
Adenosine receptor A1	0	9	7	21
Adenosine receptor A2a	0	7	3	17
Vasopressin V2 receptor	0	0	0	3
Mu-type opioid receptor	0	18	6	26
Adenosine receptor A1	0	4	2	6
Adenylate cyclase type 5	0	2	0	3
Adenylate cyclase type 1	0	0	0	3
Sigma non-opioid intracellular receptor 1	0	8	1	9
dopamine D1 receptor	4	0	0	4
GLS protein	23	0	0	23
regulator of G-protein signaling 4	21	0	0	21
DNA polymerase kappa isoform 1	7	0	0	7
histone acetyltransferase KAT2A isoform 1	16	0	0	16
Mu-type opioid receptor	0	9	3	12
ATP-dependent phosphofructokinase	17	0	0	17
Chain A, Beta-lactamase	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	31	0	0	31
IDH1	16	0	0	16
Phosphatidylinositol 4-kinase alpha	0	5	0	6
Xanthine dehydrogenase/oxidase	0	1	0	1
Guanine nucleotide-binding protein G	3	0	0	3
TAR DNA-binding protein 43	9	0	0	9
Phosphatidylinositol 4-kinase type 2-beta	0	5	0	6
Phosphatidylinositol 4-kinase type 2-alpha	0	5	0	6
Phosphatidylinositol 4-kinase beta	0	5	0	6
acetylcholinesterase	22	0	0	22
GLI family zinc finger 3	40	0	0	40
nuclear receptor subfamily 1, group I, member 3	34	0	0	34
pregnane X nuclear receptor	36	0	0	36
thyroid stimulating hormone receptor	14	0	0	14
Histone H2A.x	20	0	0	20
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	13	0	0	13
Chain A, Cruzipain	5	0	0	5
RAR-related orphan receptor gamma	35	0	0	35
USP1 protein, partial	19	0	0	19
Microtubule-associated protein tau	15	0	0	15
estrogen receptor 2 (ER beta)	20	0	0	20
cytochrome P450 family 3 subfamily A polypeptide 4	32	0	0	32
glucocorticoid receptor [Homo sapiens]	35	0	0	35
cytochrome P450 2D6	27	0	0	27
glucocerebrosidase	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	15	0	0	15
cytochrome P450 2D6 isoform 1	13	0	0	13
transcriptional regulator ERG isoform 3	5	0	0	5
thyroid hormone receptor beta isoform 2	36	0	0	36
mitogen-activated protein kinase 1	10	0	0	10
peripheral myelin protein 22	24	0	0	24
survival motor neuron protein isoform d	12	0	0	12
lethal factor (plasmid)	9	0	0	9
Potassium channel subfamily K member 2	0	5	6	11
Rap guanine nucleotide exchange factor 3	3	0	0	3
Cellular tumor antigen p53	33	0	0	33
Potassium voltage-gated channel subfamily A member 3	0	0	1	1
Acetylcholinesterase	0	2	0	2
Pteridine reductase 1	0	3	0	3
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	25	0	25
5-hydroxytryptamine receptor 2C	0	11	1	12
5-hydroxytryptamine receptor 2A	0	12	1	14
5-hydroxytryptamine receptor 1A	0	21	3	26
5-hydroxytryptamine receptor 1B	0	15	1	17
5-hydroxytryptamine receptor 1D	0	4	1	6
5-hydroxytryptamine receptor 1F	0	4	1	6
5-hydroxytryptamine receptor 2B	0	11	1	12
5-hydroxytryptamine receptor 6	0	2	1	3
Sodium-dependent serotonin transporter	0	15	3	18
Sodium-dependent serotonin transporter	0	9	0	9
5-hydroxytryptamine receptor 7	0	5	1	6
5-hydroxytryptamine receptor 5A	0	2	1	3
5-hydroxytryptamine receptor 5B	0	2	1	3
5-hydroxytryptamine receptor 3A	0	4	1	5
5-hydroxytryptamine receptor 4	0	2	1	3
5-hydroxytryptamine receptor 3B	0	4	1	5
phosphopantetheinyl transferase	18	0	0	18
mu-type opioid receptor isoform MOR-1	0	0	4	4
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
5-hydroxytryptamine receptor 2A	0	0	4	4
Gamma-aminobutyric acid receptor subunit pi	16	11	2	29
Cytochrome P450 3A4	0	6	1	8
Neuronal acetylcholine receptor subunit alpha-4	3	5	2	11
Cytochrome P450 2C9	0	12	0	12
Neuronal acetylcholine receptor subunit beta-2	3	5	2	11
D(2) dopamine receptor	0	20	0	21
Gamma-aminobutyric acid receptor subunit beta-1	16	11	2	29
Alpha-1B adrenergic receptor	0	18	1	19
Translocator protein	0	5	2	8
Gamma-aminobutyric acid receptor subunit delta	16	11	2	29
Gamma-aminobutyric acid receptor subunit gamma-2	16	11	4	31
D	0	7	0	7
D(3) dopamine receptor	0	9	0	9
Alpha-2B adrenergic receptor	0	14	1	16
Gamma-aminobutyric acid receptor subunit alpha-5	16	11	2	29
Gamma-aminobutyric acid receptor subunit alpha-3	16	11	2	29
D(2) dopamine receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	14	1	16
Alpha-2A adrenergic receptor	0	14	1	16
Gamma-aminobutyric acid receptor subunit gamma-1	16	11	2	29
Gamma-aminobutyric acid receptor subunit alpha-2	16	11	2	29
Alpha-1D adrenergic receptor	0	14	1	16
Sodium-dependent dopamine transporter	0	7	0	7
Alpha-1D adrenergic receptor	0	19	2	22
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	1	2
5-hydroxytryptamine receptor 2C	0	22	0	22
Gamma-aminobutyric acid receptor subunit alpha-4	16	11	2	29
Gamma-aminobutyric acid receptor subunit gamma-3	16	11	2	29
Gamma-aminobutyric acid receptor subunit alpha-6	16	11	2	29
5-hydroxytryptamine receptor 7	0	4	0	4
Alpha-1A adrenergic receptor	0	3	2	6
Alpha-1B adrenergic receptor	0	3	2	6
Alpha-1A adrenergic receptor	0	19	2	21
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 6	0	16	0	16
5-hydroxytryptamine receptor 7	0	9	0	9
D(2) dopamine receptor	0	12	0	13
Gamma-aminobutyric acid receptor subunit alpha-1	16	12	4	32
Gamma-aminobutyric acid receptor subunit beta-3	16	11	2	29
Gamma-aminobutyric acid receptor subunit beta-2	16	11	4	31
D	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
GABA theta subunit	16	11	2	29
Sigma non-opioid intracellular receptor 1	0	20	1	21
Gamma-aminobutyric acid receptor subunit epsilon	16	11	2	29
Lysosomal alpha-glucosidase	0	2	0	2
Transporter	0	6	1	8
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	16	0	0	16
Chain B, HADH2 protein	16	0	0	16
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Ferritin light chain	8	0	0	8
Thymidine kinase	0	2	0	3
Smad3	5	0	0	5
EWS/FLI fusion protein	20	0	0	20
arylsulfatase A	22	0	0	22
activating transcription factor 6	17	0	0	17
Bloom syndrome protein isoform 1	14	0	0	14
hemoglobin subunit beta	2	0	0	2
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Solute carrier family 22 member 1	0	17	0	23
ATP-binding cassette sub-family C member 3	0	39	0	39
Multidrug resistance-associated protein 4	0	39	0	40
Solute carrier family 22 member 6	0	3	0	4
Bile salt export pump	0	9	0	9
Bile salt export pump	0	64	0	64
Purine nucleoside phosphorylase	0	2	0	2
Thymidine kinase, cytosolic	0	2	0	5
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2J2	0	7	0	7
Disintegrin and metalloproteinase domain-containing protein 17	4	0	0	4
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	1	0	3
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	4
Canalicular multispecific organic anion transporter 1	0	38	0	38
Thymidine kinase	0	1	0	2
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Membrane lipoprotein tmpC	0	0	1	1
Chain A, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain B, Structure of PAE2307 in complex with adenosine	0	0	1	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, ADENOSINE RECEPTOR A2A	0	1	0	1
Chain A, tRNA (guanine-N(1)-)-methyltransferase	0	0	1	1
Chain A, Uncharacterized protein MJ0883	0	0	1	1
AR protein	55	0	0	55
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
retinoid X nuclear receptor alpha	31	0	0	31
estrogen nuclear receptor alpha	66	0	0	66
NPYLR7B	0	0	3	3
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
flap endonuclease 1	8	0	0	8
high affinity choline transporter 1 isoform a	0	1	0	1
Sodium/nucleoside cotransporter 1	0	2	0	2
Calcium dependent protein kinase	0	1	0	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Sodium/nucleoside cotransporter 2	0	2	0	2
Voltage-dependent calcium channel gamma-2 subunit	18	0	0	18
Epidermal growth factor receptor	0	5	0	5
Phosphoglycerate kinase 1	0	1	0	1
Adenosine deaminase	0	0	0	1
Avidin	0	0	1	1
Adenosine deaminase	0	0	0	1
Glyceraldehyde-3-phosphate dehydrogenase	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	4	0	4
Insulin receptor	0	0	0	1
Phosphoglycerate kinase 2	0	1	0	1
Heat shock protein HSP 90-alpha	0	1	2	3
Platelet-derived growth factor receptor beta	0	0	0	1
Heat shock 70 kDa protein 1A	0	1	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	1	0	1
Endoplasmin	0	1	1	2
Glutamate receptor 2	18	2	1	21
Inosine-5'-monophosphate dehydrogenase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	0	1
Fibroblast growth factor receptor 4	0	0	0	1
Fibroblast growth factor receptor 3	0	0	0	1
Streptavidin	0	0	1	1
Adenosylhomocysteinase	0	0	0	1
Adenylate kinase 2, mitochondrial	0	1	0	1
Adenylate kinase isoenzyme 1	0	1	0	1
Adenosine kinase	0	0	0	1
Adenosine deaminase	0	0	0	1
Equilibrative nucleoside transporter 2	0	2	0	2
Histone-lysine N-methyltransferase, H3 lysine-79 specific	0	1	0	1
Equilibrative nucleoside transporter 1	0	2	0	2
Solute carrier family 28 member 3	0	2	0	2
Adenosine kinase	0	1	0	2
5-methylthioadenosine/S-adenosylhomocysteine deaminase	0	0	0	1
Adenosine transporter 1	0	0	0	1
retinoic acid nuclear receptor alpha variant 1	38	0	0	38
Botulinum neurotoxin type A	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	3	0	3
Nitric oxide synthase, brain	0	3	0	3
Nitric oxide synthase, brain	0	3	0	3
Nitric oxide synthase, inducible	0	3	0	3
Kappa-type opioid receptor	0	7	2	9
Tyrosine-protein kinase	0	0	1	1
glp-1 receptor, partial	12	0	0	12
aryl hydrocarbon receptor	22	0	0	22
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
urokinase-type plasminogen activator precursor	5	0	0	5
plasminogen precursor	5	0	0	5
urokinase plasminogen activator surface receptor precursor	5	0	0	5
POU domain, class 2, transcription factor 1	0	0	0	3
Luciferase	14	0	0	14
interleukin 8	6	0	0	6
15-lipoxygenase, partial	7	0	0	7
G	16	0	0	16
peroxisome proliferator-activated receptor delta	17	0	0	17
vitamin D (1,25- dihydroxyvitamin D3) receptor	25	0	0	25
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	22	0	0	22
v-jun sarcoma virus 17 oncogene homolog (avian)	21	0	0	21
thyroid hormone receptor beta isoform a	12	0	0	12
histone deacetylase 9 isoform 3	3	0	0	3
nuclear factor erythroid 2-related factor 2 isoform 1	36	0	0	36
Interferon beta	22	0	0	22
HLA class I histocompatibility antigen, B alpha chain	16	0	0	16
Nicotinate phosphoribosyltransferase	0	3	0	3
Inositol hexakisphosphate kinase 1	16	0	0	16
cytochrome P450 2C9, partial	16	0	0	16
ORF73	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
SMAD family member 2	7	0	0	7
Fumarate hydratase	10	0	0	10
NFKB1 protein, partial	7	0	0	7
PPM1D protein	6	0	0	6
SMAD family member 3	7	0	0	7
Thrombopoietin	4	0	0	4
caspase 7, apoptosis-related cysteine protease	7	0	0	7
progesterone receptor	25	0	0	25
farnesoid X nuclear receptor	20	0	0	20
polyprotein	10	0	0	10
peroxisome proliferator activated receptor gamma	22	0	0	22
caspase-3	7	0	0	7
cellular tumor antigen p53 isoform a	8	0	0	8
cytochrome P450 2C9 precursor	5	0	0	5
D(1A) dopamine receptor	15	0	0	15
potassium voltage-gated channel subfamily H member 2 isoform d	17	0	0	17
heat shock protein beta-1	12	0	0	12
huntingtin isoform 2	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	10	0	0	10
cytochrome P450 3A4 isoform 1	16	0	0	16
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	0	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Solute carrier organic anion transporter family member 1A4	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	9	0	9
5-hydroxytryptamine receptor 4	0	20	0	20
Lysine-specific demethylase PHF2	0	1	0	1
Thyroid hormone receptor alpha	0	1	0	1
Integrin beta-3	6	1	1	8
Tyrosine-protein kinase Fyn	0	4	0	4
ATP-dependent translocase ABCB1	0	3	0	3
Aldo-keto reductase family 1 member B1	0	19	0	19
Muscarinic acetylcholine receptor M2	0	16	1	20
Muscarinic acetylcholine receptor M4	0	14	1	17
ATP-dependent translocase ABCB1	0	12	1	16
Integrin alpha-IIb	6	1	1	8
Beta-1 adrenergic receptor	0	6	2	8
Muscarinic acetylcholine receptor M5	0	14	1	17
Alpha-2A adrenergic receptor	0	17	3	20
Cytochrome P450 2C8	0	2	0	2
Thyroid hormone receptor alpha	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Muscarinic acetylcholine receptor M1	0	16	1	20
Beta-3 adrenergic receptor	0	5	2	7
Androgen receptor	0	6	0	6
Lethal factor	0	2	0	2
Alpha-2B adrenergic receptor	0	18	1	19
Thyroid hormone receptor beta	0	2	0	2
Muscarinic acetylcholine receptor M3	0	16	1	19
ATP-dependent translocase ABCB1	0	3	0	3
Substance-K receptor	0	6	0	6
D(1A) dopamine receptor	0	11	0	12
D(4) dopamine receptor	0	10	0	11
Carnitine O-palmitoyltransferase 2, mitochondrial	0	1	0	1
Sodium-dependent noradrenaline transporter	0	22	2	24
Histamine H2 receptor	0	10	0	10
Endothelin-1 receptor	0	2	0	2
5-hydroxytryptamine receptor 2A	0	18	0	18
Lysine-specific demethylase 5A	0	1	0	1
B2 bradykinin receptor	0	2	0	2
Melanocortin receptor 4	0	4	0	4
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	6	0	6
D(3) dopamine receptor	0	18	0	19
Sodium channel protein type 1 subunit alpha	0	6	0	6
Sodium channel protein type 4 subunit alpha	0	7	0	8
Squalene synthase	0	1	0	1
Delta-type opioid receptor	0	15	2	19
Kappa-type opioid receptor	0	15	4	21
5-hydroxytryptamine receptor 2B	0	16	0	16
C-C chemokine receptor type 2	0	2	0	2
Melanocortin receptor 3	0	4	0	4
Histamine H2 receptor	13	2	1	19
D(1A) dopamine receptor	7	0	0	7
Carnitine O-palmitoyltransferase 1, liver isoform	0	1	0	1
C-C chemokine receptor type 4	0	2	0	2
Spike glycoprotein	23	2	3	28
Sodium channel protein type 7 subunit alpha	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1D	0	9	0	9
Sodium-dependent dopamine transporter	0	16	1	17
Voltage-dependent L-type calcium channel subunit alpha-1S	0	9	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	10	0	10
Sodium channel protein type 5 subunit alpha	0	8	0	8
Squalene monooxygenase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	10	0	10
Lysine-specific demethylase 7A	0	1	0	1
Carnitine O-palmitoyltransferase 1, muscle isoform	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	7	0	7
Ataxin-2	21	0	0	21
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	0	1	1
Sodium channel protein type 3 subunit alpha	0	8	0	8
Sodium channel protein type 11 subunit alpha	0	5	0	5
Histone lysine demethylase PHF8	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	6	0	6
Sodium channel protein type 10 subunit alpha	0	5	0	5
atrial natriuretic peptide receptor 2 precursor	5	0	0	5
Albumin	0	0	5	5
High affinity nerve growth factor receptor	0	1	2	3
Muscarinic acetylcholine receptor M1	0	8	2	12
Muscarinic acetylcholine receptor M3	0	8	2	12
Muscarinic acetylcholine receptor M4	0	9	2	13
Muscarinic acetylcholine receptor M5	0	9	2	13
Muscarinic acetylcholine receptor M2	0	9	2	14
Angiotensin-converting enzyme	0	12	0	13
Alpha-2C adrenergic receptor	0	12	1	13
D(1B) dopamine receptor	0	3	0	4
UDP-glucuronosyltransferase 1A4	0	2	0	6
Histamine H1 receptor	0	2	0	2
Histamine H1 receptor	0	15	1	16
UDP-glucuronosyltransferase 1A3	0	0	0	4
Voltage-dependent N-type calcium channel subunit alpha-1B	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	10	0	10
Histamine H3 receptor	0	4	0	4
Aromatase	0	2	0	2
Amine oxidase [flavin-containing] A	0	1	1	2
neuropeptide S receptor isoform A	2	0	0	2
Chain A, Phospholipase A2 isoform 3	0	0	1	1
Chain A, 2-oxoglutarate Oxygenase	12	0	0	12
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	1	0	0	1
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 1	0	18	0	21
Carbonic anhydrase 2	0	18	0	21
Fatty acid-binding protein, liver	0	4	0	4
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	4	0	4
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	8	0	8
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	6	0	6
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Nuclear receptor ROR-gamma	10	0	0	10
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	6	1	7
Small conductance calcium-activated potassium channel protein 3	0	1	1	2
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	2	0	0	2
short transient receptor potential channel 6 isoform 1	0	0	1	1
Muscarinic acetylcholine receptor M1	0	0	1	3
Muscarinic acetylcholine receptor M4	0	2	1	4
Reverse transcriptase/RNaseH	0	0	0	1
Muscarinic acetylcholine receptor	0	1	1	3
thioredoxin glutathione reductase	5	0	0	5
P53	1	0	0	1
M-phase phosphoprotein 8	7	0	0	7
muscleblind-like protein 1 isoform 1	3	0	0	3
ATPase family AAA domain-containing protein 5	11	0	0	11
Protein-arginine deiminase type-4	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 2	0	3	0	3
Gamma-aminobutyric acid type B receptor subunit 1	0	2	2	4
Gamma-aminobutyric acid type B receptor subunit 1	0	2	0	2
Polyphenol oxidase 2	0	3	0	4
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
vitamin D3 receptor isoform VDRA	10	0	0	10
caspase-1 isoform alpha precursor	1	0	0	1
Caspase-7	1	0	0	1
Inositol monophosphatase 1	8	0	0	8
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Solute carrier organic anion transporter family member 1B1	0	2	0	3
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	2
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
Caspase-7	6	0	0	6
caspase-3	6	0	0	6
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	2
Histone deacetylase 3	0	4	0	4
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	5	0	6
Prothrombin	0	2	1	3
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 3	0	4	0	4
Cathepsin B	0	1	0	1
Neutrophil elastase	0	2	0	2
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	2	0	2
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	3
Carbonic anhydrase 4	0	11	0	12
Carbonic anhydrase 6	0	6	0	7
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	2
Proteasome subunit alpha type-2	0	1	0	2
Proteasome subunit alpha type-3	0	1	0	2
Proteasome subunit alpha type-4	0	1	0	2
Proteasome subunit beta type-8	0	1	0	2
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	2
Proteasome subunit alpha type-5	0	1	0	2
Proteasome subunit beta type-4	0	1	0	2
Proteasome subunit beta type-6	0	1	0	2
Proteasome subunit beta type-5	0	2	0	4
Carbonic anhydrase 5A, mitochondrial	0	6	0	7
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	2
Carbonic anhydrase 7	0	6	0	7
26S proteasome regulatory subunit 6B	0	1	0	1
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	2
Proteasome subunit beta type-2	0	1	0	3
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	1	3
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	4	0	4
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	7	0	8
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	2	0	2
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	2
Histone deacetylase 2	0	4	0	4
Proteasome subunit beta type-7	0	1	0	2
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	8	0	8
Histone deacetylase 8	0	4	0	4
Histone deacetylase 6	0	4	0	4
Carbonic anhydrase 14	0	5	0	6
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	6	0	7
relaxin receptor 1 isoform 1	2	0	0	2
Potassium channel subfamily K member 3	0	5	0	5
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 9	0	2	0	2
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Glycogen phosphorylase, liver form	0	0	2	2
Chain A, Chitinase	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	3	0	3
Cholinesterase	0	9	0	9
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	4	3	7
Replicase polyprotein 1ab	0	4	3	7
Amine oxidase [flavin-containing] A	0	4	0	4
Acetylcholinesterase	0	16	1	18
Amine oxidase [flavin-containing] B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	6	0	6
Serine/threonine-protein kinase mTOR	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Chitotriosidase-1	0	4	1	5
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	4	1	5
Phosphodiesterase	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	0	2
Guanine deaminase	0	2	0	2
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Metallo-beta-lactamase type 2	0	1	1	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Neprilysin	0	2	0	2
Neprilysin	0	2	0	2
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	2	0	2
Angiotensin-converting enzyme	0	5	1	6
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	2
Endothelin-converting enzyme 1	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Solute carrier family 15 member 1	0	2	0	2
Beta-lactamase TEM	0	1	0	1
Beta-lactamase	0	3	0	4
Beta-lactamase	0	3	0	3
Angiotensin-converting enzyme 2	0	3	3	6
Beta-lactamase class B VIM-2	0	1	1	2
Carbonic anhydrase	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	0	5
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	0	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	0	9	5	14
Gamma-aminobutyric acid receptor subunit gamma-2	0	8	4	12
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	0	5
Gamma-aminobutyric acid receptor subunit beta-3	0	9	3	12
Cholecystokinin receptor type A	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	0	7	5	12
Gamma-aminobutyric acid receptor subunit alpha-3	0	7	3	10
Gamma-aminobutyric acid receptor subunit alpha-2	0	7	4	11
NADPH oxidase 1	0	2	0	2
Snq2p	0	0	0	4
Adenylate cyclase type 1	0	2	0	2
Spike glycoprotein	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
ras-related protein Rab-9A	4	0	0	4
Transmembrane protease serine 2	0	2	3	5
Glutamate receptor ionotropic, NMDA 2D	0	3	0	3
Transient receptor potential cation channel subfamily V member 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	3	0	3
Albumin	0	5	5	11
Major prion protein	0	0	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Major prion protein	0	0	1	1
Cytochrome P450 1A2	0	2	1	4
Procathepsin L	0	2	3	5
Replicase polyprotein 1a	0	2	3	5
Replicase polyprotein 1ab	0	2	3	5
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Cytochrome P450 2D6	0	13	1	14
Polyunsaturated fatty acid lipoxygenase ALOX15	0	4	0	4
Sphingomyelin phosphodiesterase	0	2	0	2
Adenylate cyclase type 3	0	2	0	2
D(1B) dopamine receptor	0	6	0	6
Adenylate cyclase type 2	0	2	0	2
Adenylate cyclase type 4	0	2	0	2
Trypanothione reductase	0	6	0	6
D(4) dopamine receptor	0	6	0	6
Histamine H1 receptor	0	1	1	2
Pleiotropic ABC efflux transporter of multiple drugs	0	4	0	8
Glutamate receptor ionotropic, NMDA 1	1	7	2	10
Adenylate cyclase type 8	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	0	1
Calmodulin	0	1	1	2
Aldehyde oxidase 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	6	2	8
Glutamate receptor ionotropic, NMDA 2B	0	6	2	8
Glutamate receptor ionotropic, NMDA 2C	0	6	2	9
Adenylate cyclase type 6	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Aldehyde oxidase	0	2	0	2
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	3	0	3
Glutamate receptor ionotropic, NMDA 2D	0	6	2	8
Adenylyl cyclase 7	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	3	0	3
Glutamate receptor ionotropic, NMDA 3B	0	6	2	8
D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	6	2	8
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	3	0	4
Solute carrier family 22 member 2	0	5	0	7
Solute carrier family 22 member 2	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-3	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-2	0	3	2	6
Neuronal acetylcholine receptor subunit beta-3	0	3	2	6
Neuronal acetylcholine receptor subunit beta-4	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-5	0	3	2	6
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-9	0	3	2	6
Neuronal acetylcholine receptor subunit alpha-7	0	4	2	7
Solute carrier family 22 member 1	0	10	0	13
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	3	2	6
Solute carrier family 22 member 2	0	9	0	11
Beta-1 adrenergic receptor	0	0	2	3
Alpha-1B adrenergic receptor	0	0	1	1
cytochrome P450 2C19 precursor	5	0	0	5
Membrane primary amine oxidase	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
Solute carrier family 22 member 3	0	6	0	7
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-2B adrenergic receptor	0	1	0	2
Delta-type opioid receptor	0	8	1	12
Alpha-2C adrenergic receptor	0	1	0	2
Alpha-2A adrenergic receptor	0	1	0	2
Alpha-2A adrenergic receptor	0	1	0	1
Nischarin	0	2	0	2
Multidrug and toxin extrusion protein 1	0	6	0	6
Nischarin	0	1	0	1
Phosphodiesterase	0	3	0	3
Multidrug resistance-associated protein 5	0	0	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
pregnane X receptor	4	0	0	4
chaperonin GroEL	1	0	0	1
Sodium-dependent noradrenaline transporter	0	3	0	3
Glycogen phosphorylase, brain form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Endothelin receptor type B	0	1	0	1
Endothelin receptor type B	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	3	0	3
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Gamma-aminobutyric acid	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	5	0	5
Gamma-aminobutyric acid receptor subunit delta	0	5	0	5
Alpha-1-acid glycoprotein 1	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	5	2	7
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	5	4	9
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	2	7
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-6	0	6	2	8
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	5	0	5
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	5	0	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	5	0	5
lysosomal alpha-glucosidase preproprotein	3	0	0	3
polyadenylate-binding protein 1	0	1	0	1
Cereblon isoform 4	0	4	0	4
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	4	1	6
GALC protein	3	0	0	3
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
Tyrosine-protein kinase Lck	0	1	0	1
Beta-2 adrenergic receptor	0	4	5	10
Eyes absent homolog 2	0	1	0	1
Amyloid-beta precursor protein	0	1	0	1
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Acetylcholinesterase	0	5	0	5
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Delta-type opioid receptor	0	9	3	13
Mu-type opioid receptor	0	10	4	17
Kappa-type opioid receptor	0	6	3	10
Mu-type opioid receptor	0	4	1	9
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
importin subunit beta-1 isoform 1	5	0	0	5
snurportin-1	5	0	0	5
GTP-binding nuclear protein Ran isoform 1	3	0	0	3
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
Sodium channel protein type 1 subunit alpha	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
Cytochrome P450 2C19	0	2	0	3
Gastrin/cholecystokinin type B receptor	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	5	0	5
Cytochrome P450 1B1	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
Transporter	0	1	0	1
Beta-2 adrenergic receptor	0	3	2	5
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Tyrosyl-DNA phosphodiesterase 1	0	1	0	1
thyrotropin-releasing hormone receptor	1	0	0	1
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Serum paraoxonase/arylesterase 1	0	2	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Carbonic anhydrase 13	0	5	0	7
G-protein coupled receptor 35	0	1	1	2
CDGSH iron-sulfur domain-containing protein 1	0	2	0	2
endonuclease IV	4	0	0	4
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
bromodomain adjacent to zinc finger domain 2B	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Sodium- and chloride-dependent GABA transporter 1	0	3	0	3
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	3	0	3
Sodium- and chloride-dependent GABA transporter 3	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	3	0	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Histone deacetylase 4	0	3	0	3
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	0	0	1
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	3	0	3
Histone deacetylase 7	0	3	0	3
Polyamine deacetylase HDAC10	0	3	0	3
Histone deacetylase 11	0	3	0	3
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	5	0	0	5
Metabotropic glutamate receptor 8	0	2	0	2
Metabotropic glutamate receptor 6	0	1	1	3
Excitatory amino acid transporter 4	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	2	1	3
Glutamate receptor 3	0	2	1	3
Glutamate receptor 4	0	2	1	3
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Excitatory amino acid transporter 1	0	2	0	3
Excitatory amino acid transporter 2	0	2	0	3
Excitatory amino acid transporter 3	0	2	0	3
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	3	0	3
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 1	0	1	1	3
Metabotropic glutamate receptor 2	0	1	1	3
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Liver carboxylesterase 1	0	1	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	2	0	2
Carbonic anhydrase	0	2	0	2
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Envelope glycoprotein	0	0	1	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Acetylcholinesterase	0	6	3	10
Acetylcholinesterase	0	1	1	2
Fatty acid synthase	0	1	0	1
Liver carboxylesterase	0	1	0	1
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
Beta-2 adrenergic receptor	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	4
Beta-2 adrenergic receptor	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	3	3
Beta-3 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	1	1	2
Vasopressin V1a receptor	0	0	1	1
Beta-1 adrenergic receptor	0	1	1	2
Beta-2 adrenergic receptor	0	1	0	1
Taste receptor type 2 member 38	0	0	1	1
Taste receptor type 2 member 39	0	0	1	1
Taste receptor type 2 member 40	0	0	1	1
Taste receptor type 2 member 41	0	0	1	1
Taste receptor type 2 member 43	0	0	1	1
Taste receptor type 2 member 31	0	0	1	1
Taste receptor type 2 member 45	0	0	1	1
Taste receptor type 2 member 46	0	0	1	1
Taste receptor type 2 member 30	0	0	1	1
Taste receptor type 2 member 19	0	0	1	1
Taste receptor type 2 member 20	0	0	1	1
Taste receptor type 2 member 50	0	0	1	1
Taste receptor type 2 member 60	0	0	1	1
Oxytocin receptor	0	0	1	1
Beta-2 adrenergic receptor	0	1	3	6
Taste receptor type 2 member 42	0	0	1	1
Taste receptor type 2 member 16	0	0	1	1
Taste receptor type 2 member 14	0	0	1	1
Taste receptor type 2 member 13	0	0	1	1
Taste receptor type 2 member 10	0	0	1	1
Taste receptor type 2 member 9	0	0	1	1
Taste receptor type 2 member 8	0	0	1	1
Taste receptor type 2 member 7	0	0	1	1
Taste receptor type 2 member 5	0	0	1	1
Taste receptor type 2 member 4	0	0	1	1
Taste receptor type 2 member 3	0	0	1	1
Taste receptor type 2 member 1	0	0	1	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	1	2
Caspase-1	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	3	0	3
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	2	0	0	2
Carboxylic ester hydrolase	0	2	0	2
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Cytochrome P450 2B6	0	2	0	2
Mas-related G-protein coupled receptor member X2	0	0	2	2
Aldehyde oxidase 1	0	1	0	1
nonstructural protein 1	4	0	0	4
Glucocorticoid receptor	0	8	2	15
Glycine receptor subunit alpha-1	0	8	0	8
Glycine receptor subunit beta	0	8	0	8
Glycine receptor subunit alpha-2	0	8	0	8
Glycine receptor subunit alpha-3	0	8	0	8
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
UDP-glucuronosyltransferase 2B7	0	2	0	3
UDP-glucuronosyltransferase 1-6	0	1	0	2
UDP-glucuronosyltransferase 1A1	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Opioid receptor, delta 1b	0	1	0	1
Opioid receptor homologue	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Histidine decarboxylase	0	0	2	2
Proteinase-activated receptor 1	0	2	1	3
Kappa-type opioid receptor	0	3	1	7
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	1	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
Cholinesterase	0	3	0	4
5-hydroxytryptamine receptor 3E	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit alpha	0	2	1	3
Acetylcholine receptor subunit beta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Acetylcholine receptor subunit delta	0	2	1	3
Acetylcholine receptor subunit gamma	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Acetylcholine receptor subunit beta	0	2	1	3
Cytochrome P450 2A6	0	3	1	4
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Cytochrome P450 2A5	0	1	0	1
Acetylcholine receptor subunit beta-like 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	0	1	1
Neuronal acetylcholine receptor subunit beta-4	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-3	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-7	0	2	2	4
Neuronal acetylcholine receptor subunit alpha-4	0	2	1	3
5-hydroxytryptamine receptor 3A	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Acetylcholine-binding protein	0	1	1	2
Acetylcholine receptor subunit epsilon	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	1	1	2
Acetylcholine receptor subunit delta	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	1	2
Cytochrome P450 2A13	0	1	1	2
Neuronal acetylcholine receptor subunit alpha-5	0	2	0	2
Liver carboxylesterase B-1	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Neuronal acetylcholine receptor subunit beta-3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Soluble acetylcholine receptor	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	0	2	1	3
Neuronal acetylcholine receptor subunit alpha-6	0	2	0	2
Integrin beta	0	0	1	1
Glycoprotein IIb	0	0	1	1
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
4-hydroxyphenylpyruvate dioxygenase	0	1	0	1
Sodium/iodide cotransporter	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	2
Nitric oxide synthase, endothelial	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Collagenase 3	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Xaa-Pro dipeptidase	0	0	0	1
vasopressin V1b receptor	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Tumor necrosis factor	0	1	0	1
Alpha-synuclein	2	0	0	2
Chain A, Immunoglobulin	0	0	1	1
Chain B, Immunoglobulin	0	0	1	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Cholinesterase	0	2	0	2
Muscarinic acetylcholine receptor M5	0	0	1	2
Muscarinic acetylcholine receptor M3	0	0	1	2
Muscarinic acetylcholine receptor M2	0	0	1	2
Vpr	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chain E, THERMOLYSIN	0	1	0	1
Chain E, Thermolysin	0	1	0	1
Thermolysin	0	2	0	2
Neprilysin	0	2	0	2
P2Y purinoceptor 12	0	1	0	1
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Sterol O-acyltransferase 1	0	1	0	1
Solute carrier family 22 member 4	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Glutamate 5-kinase	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	2
Monocarboxylate transporter 4	0	0	0	1
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Histidine-rich protein PFHRP-II	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
Parkin	1	0	0	1
pyruvate kinase	1	0	0	1
pyruvate kinase PKM isoform b	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Ornithine decarboxylase	1	0	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	1	0	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	1	0	2
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	0	0	1
cGMP-gated cation channel alpha-1	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Thymidine kinase	0	1	0	2
Thymidylate synthase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Interleukin-8	0	1	0	1
Lactoylglutathione lyase	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit	0	1	0	1
Seminal ribonuclease	0	1	0	1
Ribonucleoside-diphosphate reductase large subunit	0	0	0	1
Ribonucleoside-diphosphate reductase subunit M2	0	0	0	1
P2Y purinoceptor 2	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 4	0	0	1	1
Ribonuclease pancreatic	0	1	0	1
UDP-galactopyranose mutase	0	0	1	1
P2Y purinoceptor 6	0	0	1	1
P2Y purinoceptor 14	0	0	1	1
UDP-galactopyranose mutase	0	0	1	1
P2Y purinoceptor 6	0	0	1	1
Ribonucleoside-diphosphate reductase subunit M2 B	0	0	0	1
Solute carrier family 15 member 1	0	2	0	3
Solute carrier family 15 member 2	0	1	0	1
Valacyclovir hydrolase	0	0	0	1
Chain A, Arginase 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Cocaine esterase	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
ClpP	1	0	0	1
POsterior Segregation	0	0	1	1
DNA topoisomerase 1	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
M-phase inducer phosphatase 1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Zinc finger protein mex-5	0	0	1	1
Butyrophilin subfamily 3 member A1	0	0	1	2
Geranylgeranyl pyrophosphate synthase	0	2	0	3
72 kDa type IV collagenase	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Matrix metalloproteinase-9	0	1	0	1
Neutrophil collagenase	0	1	0	1
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Farnesyl pyrophosphate synthase	0	2	0	2
Geranylgeranyl pyrophosphate synthase	0	2	0	2
Farnesyl pyrophosphate synthase	0	1	0	1
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (342)

Protein Targets (1,280)

Diaphragmatic Paralysis

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (342)

Drugs Studied (239)

Protein Targets (1,280)