Page last updated: 2024-09-28

Male Genital Tuberculosis

MYCOBACTERIUM infections of the male reproductive tract (GENITALIA, MALE).

Synonyms(2)

Synonym
Male Genital Tuberculosis
Tuberculosis, Male Genital

Research

Studies (74)

TimeframeStudies, This Condition (%)All Conditions %
pre-199042 (56.76)23.3326
1990's6 (8.11)12.5806
2000's14 (18.92)18.1394
2010's10 (13.51)28.8240
2020's2 (2.70)9.53
DrugIndicatedRelationship StrengthStudiesTrials
niacin0low50
pyrazinamide0low100
pyridoxine0low30
urea0low10
aspirin0low10
iothalamic acid0low10
isoniazid0low390
metronidazole0low20
aminosalicylic acid0low50
phenobarbital0low10
praziquantel0low10
procaine0low10
sulfamethoxazole0low10
trimethoprim0low10
prednisolone0low10
prednisone0low10
oxazoles0low10
lucanthone hydrochloride0low10
ethambutol0low120
sulfur hexafluoride0low10
streptomycin0low170
dihydrostreptomycin sulfate0low30
fludrocortisone0low10
fluorodeoxyglucose f180low20
cortisone0low10
D-fructopyranose0low30
alpha-chymotrypsin0low10
clove0low30
ascorbic acid0low10
minocycline0low10
phenprocoumon0low10
rifampin0low230

Protein Targets (466)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, 2-oxoglutarate Oxygenase6006
Microtubule-associated protein tau4004
thioredoxin glutathione reductase5005
Smad31001
euchromatic histone-lysine N-methyltransferase 2120012
microphthalmia-associated transcription factor isoform 90101
Carbonic anhydrase 10506
Carbonic anhydrase 20506
Tyrosine-protein phosphatase non-receptor type 10011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase7007
phosphopantetheinyl transferase3003
NFKB1 protein, partial2002
GLS protein6006
thyroid stimulating hormone receptor9009
alpha-galactosidase1001
cytochrome P450 2C19 precursor2002
chromobox protein homolog 17007
flap endonuclease 13003
DNA polymerase iota isoform a (long)4004
muscarinic acetylcholine receptor M16006
lethal factor (plasmid)5005
Cytochrome P450 3A40304
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase4004
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase2002
RAR-related orphan receptor gamma7007
GLI family zinc finger 3120012
AR protein140014
cytochrome P450 family 3 subfamily A polypeptide 47007
glucocorticoid receptor [Homo sapiens]100010
retinoic acid nuclear receptor alpha variant 1120012
estrogen-related nuclear receptor alpha110011
estrogen nuclear receptor alpha180018
vitamin D (1,25- dihydroxyvitamin D3) receptor8008
IDH13003
nuclear factor erythroid 2-related factor 2 isoform 23003
thyroid hormone receptor beta isoform 26006
nuclear factor erythroid 2-related factor 2 isoform 18008
lethal(3)malignant brain tumor-like protein 1 isoform I1001
geminin8008
lamin isoform A-delta107007
Polyphenol oxidase 20303
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0011
Spike glycoprotein2002
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 85005
aldehyde dehydrogenase 1 family, member A1130013
hypothetical protein, conserved1001
EWS/FLI fusion protein6006
cytochrome P450 2D62002
glucocerebrosidase1001
peroxisome proliferator-activated receptor delta6006
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Bloom syndrome protein isoform 14004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
DNA polymerase kappa isoform 11001
Prostaglandin-H2 D-isomerase0101
ATP-binding cassette sub-family C member 3011011
Multidrug resistance-associated protein 4011011
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Bile salt export pump016016
Epidermal growth factor receptor0101
Fatty acid-binding protein, liver0202
Integrin beta-30101
Myeloperoxidase0303
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb0101
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10202
Adenosine receptor A10101
Adenosine receptor A2a0101
Substance-P receptor0202
Prostaglandin G/H synthase 20303
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma3003
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-15207
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Canalicular multispecific organic anion transporter 1011011
Sigma non-opioid intracellular receptor 10011
Sigma non-opioid intracellular receptor 10011
Carbonic anhydrase 40102
Carbonic anhydrase0102
Carbonic anhydrase 150102
Chain A, Cruzipain2002
TDP1 protein8008
cytochrome P450 2C9 precursor1001
Gamma-aminobutyric acid receptor subunit pi5106
Cytochrome P450 1A20202
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit B0102
DNA gyrase subunit A0204
DNA gyrase subunit B0204
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0102
DNA topoisomerase 4 subunit A0102
Cytochrome P450 2D60202
DNA topoisomerase 2-alpha0104
Cytochrome P450 2C9 0516
Gamma-aminobutyric acid receptor subunit beta-15106
Gamma-aminobutyric acid receptor subunit delta5106
Gamma-aminobutyric acid receptor subunit gamma-25106
Gamma-aminobutyric acid receptor subunit alpha-55106
Gamma-aminobutyric acid receptor subunit alpha-35106
DNA gyrase subunit A0102
Gamma-aminobutyric acid receptor subunit gamma-15106
Gamma-aminobutyric acid receptor subunit alpha-25106
Gamma-aminobutyric acid receptor subunit alpha-45106
Gamma-aminobutyric acid receptor subunit gamma-35106
Gamma-aminobutyric acid receptor subunit alpha-65106
Cytochrome P450 2C190202
Multidrug resistance protein MdtK0011
Histamine H2 receptor2002
Gamma-aminobutyric acid receptor subunit beta-35106
Gamma-aminobutyric acid receptor subunit beta-25106
DNA gyrase subunit B0303
DNA gyrase subunit A0303
Enoyl-[acyl-carrier-protein] reductase [NADH]0207
Potassium voltage-gated channel subfamily H member 20405
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Integrase 0101
GABA theta subunit5106
Gamma-aminobutyric acid receptor subunit epsilon5106
endonuclease IV2002
dopamine D1 receptor3003
pregnane X receptor2002
progesterone receptor5005
regulator of G-protein signaling 42002
retinoid X nuclear receptor alpha7007
pregnane X nuclear receptor8008
peroxisome proliferator activated receptor gamma4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
v-jun sarcoma virus 17 oncogene homolog (avian)5005
peripheral myelin protein 22 isoform 12002
atrial natriuretic peptide receptor 1 precursor1001
heat shock protein beta-11001
survival motor neuron protein isoform d2002
cytochrome P450 3A4 isoform 15005
M-phase phosphoprotein 83003
Glucocorticoid receptor06213
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10606
Corticosteroid-binding globulin0202
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 433003
Multidrug and toxin extrusion protein 10202
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
Pantothenate synthetase0202
GALC protein1001
aryl hydrocarbon receptor5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
nuclear receptor subfamily 1, group I, member 24004
Interferon beta4004
Luciferase1001
nuclear receptor subfamily 1, group I, member 33003
67.9K protein2002
bromodomain adjacent to zinc finger domain 2B3003
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
cytochrome P450 2D6 isoform 12002
potassium voltage-gated channel subfamily H member 2 isoform d1001
nuclear receptor ROR-gamma isoform 12002
histone acetyltransferase KAT2A isoform 12002
N-glycosylase/DNA lyase0101
Bile salt export pump0606
Formamidopyrimidine-DNA glycosylase0101
Cytochrome P450 2C80101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Endonuclease III-like protein 10101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
Thioredoxin reductase 0101
Histone H2A.x2002
vitamin D3 receptor isoform VDRA3003
thyroid hormone receptor beta isoform a2002
mitogen-activated protein kinase 12002
muscleblind-like protein 1 isoform 12002
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Cellular tumor antigen p534004
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Lanosterol 14-alpha demethylase0202
Albumin0022
Stromelysin-10202
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Cytochrome P450 2J20303
Protein mono-ADP-ribosyltransferase PARP150101
Protein-arginine deiminase type-40707
Chain A, JmjC domain-containing histone demethylation protein 3A1001
glp-1 receptor, partial2002
thyrotropin-releasing hormone receptor1001
lysosomal alpha-glucosidase preproprotein1001
Amyloid-beta precursor protein0101
Neuronal acetylcholine receptor subunit alpha-41001
Cholesteryl ester transfer protein0101
Neuronal acetylcholine receptor subunit beta-21001
D-amino-acid oxidase0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Protease 0314
SMAD family member 21001
PPM1D protein2002
SMAD family member 31001
estrogen receptor 2 (ER beta)4004
arylsulfatase A3003
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b0011
cellular tumor antigen p53 isoform a1001
neuropeptide S receptor isoform A1001
luciferase0001
hypoxia-inducible factor 1 alpha subunit1001
Voltage-dependent calcium channel gamma-2 subunit1001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Glutamate receptor 21001
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
ATPase family AAA domain-containing protein 51001
Ataxin-21001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
ATAD5 protein, partial2002
USP1 protein, partial1001
NAD-dependent protein deacetylase sirtuin-60101
activating transcription factor 62002
Pyridoxal kinase0001
15-lipoxygenase, partial1001
DNA-directed RNA polymerase subunit beta0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Solute carrier organic anion transporter family member 1A40101
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0202
60 kDa heat shock protein, mitochondrial0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Caspase-10101
Alpha-synuclein0101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
10 kDa heat shock protein, mitochondrial0101
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Solute carrier organic anion transporter family member 1B30203
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Solute carrier organic anion transporter family member 1B10203
farnesoid X nuclear receptor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
ATP-dependent 6-phosphofructokinase0101
Dihydropteroate synthase0101
5-hydroxytryptamine receptor 2A0202
Dihydrofolate reductase0304
Endothelin-1 receptor0101
Chain A, Dihydrofolate Reductase0011
Chain A, Dihydrofolate reductase0101
Chain A, dihydrofolate reductase (DHFR)0101
Chain A, Dihydrofolate reductase0101
Chain A, Dihydrofolate reductase0101
Solute carrier family 22 member 1 0101
Dihydrofolate reductase 0102
Dihydrofolate reductase0404
Dihydrofolate reductase0101
Dihydrofolate reductase 0101
Dihydrofolate reductase0202
Dihydrofolate reductase0202
Dihydrofolate reductase type 10102
Dihydrofolate reductase0101
Thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase0101
Dihydrofolate reductase0202
Thymidylate synthase0101
Dihydrofolate reductase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Dihydrofolate reductase type 1 from Tn40030101
Dipeptidyl peptidase 40101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
5-hydroxytryptamine receptor 2B0101
Metabotropic glutamate receptor 50101
5-hydroxytryptamine receptor 70101
Mu-type opioid receptor0101
Bifunctional dihydrofolate reductase-thymidylate synthase0102
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Trace amine-associated receptor 50011
Dihydrofolate reductase 0202
Dihydrofolate reductase 0101
Dihydrofolate reductase0102
Dihydrofolate reductase 0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
thyroid stimulating hormone receptor2002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Carbonic anhydrase 120001
Plasma kallikrein0001
Alkaline phosphatase, tissue-nonspecific isozyme0101
Carbonic anhydrase 30001
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Carbonic anhydrase 60001
Carbonic anhydrase 5A, mitochondrial0001
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase 70001
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 90001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2D0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Carbonic anhydrase 130001
Glutamate receptor ionotropic, NMDA 3A0001
Carbonic anhydrase 140001
Phospholipase A-2-activating protein0101
Carbonic anhydrase 5B, mitochondrial0001
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
Rap guanine nucleotide exchange factor 31001
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
streptokinase A precursor0011
twin arginine protein translocation system - TatA protein0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]