Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
Beta-lactamase | 0 | 0 | 0 | 1 |
Beta-lactamase | 0 | 0 | 0 | 1 |
Beta-lactamase | 0 | 0 | 0 | 1 |
Beta-lactamase | 0 | 0 | 0 | 1 |
AR protein | 5 | 0 | 0 | 5 |
apical membrane antigen 1, AMA1 | 2 | 0 | 0 | 2 |
estrogen nuclear receptor alpha | 7 | 0 | 0 | 7 |
Beta-lactamase | 0 | 0 | 0 | 1 |
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
DNA polymerase iota isoform a (long) | 4 | 0 | 0 | 4 |
urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
plasminogen precursor | 1 | 0 | 0 | 1 |
urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
ATP-binding cassette sub-family C member 3 | 0 | 7 | 0 | 7 |
Multidrug resistance-associated protein 4 | 0 | 7 | 0 | 7 |
Bile salt export pump | 0 | 2 | 0 | 2 |
Bile salt export pump | 0 | 9 | 0 | 9 |
Beta-lactamase SHV-1 | 0 | 0 | 0 | 1 |
Beta-lactamase SHV-1 | 0 | 0 | 0 | 1 |
Cytochrome P450 2C9 | 0 | 4 | 0 | 4 |
Beta-lactamase | 0 | 0 | 0 | 1 |
Kappa-type opioid receptor | 0 | 0 | 0 | 1 |
Solute carrier family 15 member 1 | 0 | 1 | 0 | 1 |
Solute carrier family 15 member 1 | 0 | 1 | 0 | 1 |
Cytochrome P450 2J2 | 0 | 2 | 0 | 2 |
B2 metallo-beta-lactamase | 0 | 0 | 0 | 1 |
Solute carrier family 15 member 2 | 0 | 1 | 0 | 1 |
Beta-lactamase | 0 | 0 | 0 | 1 |
Beta-lactamase | 0 | 0 | 0 | 1 |
Solute carrier family 15 member 2 | 0 | 1 | 0 | 1 |
Beta-lactamase | 0 | 0 | 0 | 1 |
Beta-lactamase | 0 | 0 | 0 | 1 |
Canalicular multispecific organic anion transporter 1 | 0 | 7 | 0 | 7 |
Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
Chain A, Phospholipase A2 isoform 3 | 0 | 0 | 1 | 1 |
Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
GTP-binding protein (rab7) | 0 | 0 | 1 | 1 |
ras protein, partial | 0 | 0 | 1 | 1 |
interleukin 8 | 1 | 0 | 0 | 1 |
thioredoxin reductase | 1 | 0 | 0 | 1 |
GLS protein | 1 | 0 | 0 | 1 |
aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
hypothetical protein, conserved | 1 | 0 | 0 | 1 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 4 | 0 | 0 | 4 |
EWS/FLI fusion protein | 3 | 0 | 0 | 3 |
glucocorticoid receptor [Homo sapiens] | 5 | 0 | 0 | 5 |
retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
estrogen-related nuclear receptor alpha | 4 | 0 | 0 | 4 |
cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
glucocerebrosidase | 1 | 0 | 0 | 1 |
peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
Rac1 protein | 0 | 0 | 1 | 1 |
IDH1 | 2 | 0 | 0 | 2 |
cell division cycle 42 (GTP binding protein, 25kDa), partial | 0 | 0 | 1 | 1 |
euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
lethal factor (plasmid) | 1 | 0 | 0 | 1 |
Prostaglandin-H2 D-isomerase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
Fatty acid-binding protein, liver | 0 | 2 | 0 | 2 |
Integrin beta-3 | 0 | 1 | 0 | 1 |
Myeloperoxidase | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
Seed linoleate 13S-lipoxygenase-1 | 0 | 1 | 0 | 1 |
Integrin alpha-IIb | 0 | 1 | 0 | 1 |
Glutathione hydrolase 1 proenzyme | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 1 | 0 | 2 | 0 | 2 |
Adenosine receptor A1 | 0 | 1 | 0 | 1 |
Adenosine receptor A2a | 0 | 1 | 0 | 1 |
Substance-P receptor | 0 | 1 | 0 | 1 |
Prostaglandin G/H synthase 2 | 0 | 3 | 0 | 3 |
Urotensin-2 receptor | 0 | 1 | 0 | 1 |
4-aminobutyrate aminotransferase, mitochondrial | 0 | 1 | 0 | 1 |
Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
Ras-related protein Rab-2A | 0 | 0 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 1 | 0 | 2 |
Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
Rho-associated protein kinase 2 | 0 | 1 | 0 | 1 |
Nicotinate phosphoribosyltransferase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 20 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
Sigma non-opioid intracellular receptor 1 | 0 | 0 | 1 | 1 |
Chain A, BCL-2-RELATED PROTEIN A1 | 0 | 0 | 1 | 1 |
acetylcholinesterase | 2 | 0 | 0 | 2 |
GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
pregnane X nuclear receptor | 5 | 0 | 0 | 5 |
G | 3 | 0 | 0 | 3 |
unnamed protein product | 0 | 1 | 0 | 1 |
chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 2 |
geminin | 3 | 0 | 0 | 3 |
cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
bcl-2-like protein 11 isoform 1 | 0 | 0 | 1 | 1 |
lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
Histone deacetylase 3 | 0 | 1 | 0 | 1 |
Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
Chymotrypsinogen A | 0 | 1 | 0 | 1 |
Beta-lactamase | 0 | 1 | 0 | 1 |
Interferon beta | 4 | 0 | 0 | 4 |
HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
Steroid 17-alpha-hydroxylase/17,20 lyase | 0 | 1 | 0 | 1 |
Heme oxygenase 1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Cytochrome P450 3A4 | 0 | 3 | 0 | 3 |
Lanosterol 14-alpha demethylase | 0 | 1 | 2 | 3 |
Aromatase | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
Cytochrome P450 11B1, mitochondrial | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
Cytochrome P450 11B2, mitochondrial | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
Heme oxygenase 2 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
Malate dehydrogenase, cytoplasmic | 0 | 1 | 0 | 1 |
Histone deacetylase 4 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
Cytochrome P450 144 | 0 | 0 | 2 | 2 |
Steroid C26-monooxygenase | 0 | 0 | 2 | 2 |
Steroid C26-monooxygenase | 0 | 0 | 2 | 2 |
Mycocyclosin synthase | 0 | 0 | 1 | 1 |
Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
TAR DNA-binding protein 43 | 3 | 0 | 0 | 3 |
Histone deacetylase 1 | 0 | 1 | 0 | 1 |
Lanosterol 14-alpha demethylase | 0 | 2 | 1 | 3 |
Sterol 14-alpha demethylase | 0 | 0 | 2 | 2 |
Sterol 14-alpha demethylase | 0 | 1 | 1 | 2 |
Histone deacetylase 7 | 0 | 1 | 0 | 1 |
GABA theta subunit | 1 | 0 | 0 | 1 |
Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
Histone deacetylase 2 | 0 | 1 | 0 | 1 |
Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
Histone deacetylase 11 | 0 | 1 | 0 | 1 |
14-alpha sterol demethylase | 0 | 0 | 2 | 2 |
Histone deacetylase 8 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
Histone deacetylase 6 | 0 | 1 | 0 | 1 |
Histone deacetylase 9 | 0 | 1 | 0 | 1 |
Histone deacetylase 5 | 0 | 1 | 0 | 1 |
cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
heat shock protein 90, putative | 0 | 0 | 0 | 2 |
likely tRNA 2'-phosphotransferase | 0 | 1 | 0 | 1 |
Menin | 0 | 0 | 1 | 1 |
Lecithin retinol acyltransferase | 0 | 1 | 0 | 1 |
30S ribosomal protein S6 | 0 | 1 | 0 | 1 |
30S ribosomal protein S7 | 0 | 1 | 0 | 1 |
50S ribosomal protein L15 | 0 | 1 | 0 | 1 |
50S ribosomal protein L10 | 0 | 1 | 0 | 1 |
50S ribosomal protein L11 | 0 | 1 | 0 | 1 |
50S ribosomal protein L7/L12 | 0 | 1 | 0 | 1 |
50S ribosomal protein L19 | 0 | 1 | 0 | 1 |
50S ribosomal protein L1 | 0 | 1 | 0 | 1 |
50S ribosomal protein L20 | 0 | 1 | 0 | 1 |
50S ribosomal protein L27 | 0 | 1 | 0 | 1 |
50S ribosomal protein L28 | 0 | 1 | 0 | 1 |
50S ribosomal protein L29 | 0 | 1 | 0 | 1 |
50S ribosomal protein L31 | 0 | 1 | 0 | 1 |
50S ribosomal protein L31 type B | 0 | 1 | 0 | 1 |
50S ribosomal protein L32 | 0 | 1 | 0 | 1 |
50S ribosomal protein L33 | 0 | 1 | 0 | 1 |
50S ribosomal protein L34 | 0 | 1 | 0 | 1 |
50S ribosomal protein L35 | 0 | 1 | 0 | 1 |
50S ribosomal protein L36 | 0 | 1 | 0 | 1 |
30S ribosomal protein S10 | 0 | 1 | 0 | 1 |
30S ribosomal protein S11 | 0 | 1 | 0 | 1 |
30S ribosomal protein S12 | 0 | 1 | 0 | 1 |
30S ribosomal protein S13 | 0 | 1 | 0 | 1 |
30S ribosomal protein S16 | 0 | 1 | 0 | 1 |
30S ribosomal protein S18 | 0 | 1 | 0 | 1 |
30S ribosomal protein S19 | 0 | 1 | 0 | 1 |
30S ribosomal protein S20 | 0 | 1 | 0 | 1 |
30S ribosomal protein S2 | 0 | 1 | 0 | 1 |
30S ribosomal protein S3 | 0 | 1 | 0 | 1 |
30S ribosomal protein S4 | 0 | 1 | 0 | 1 |
30S ribosomal protein S5 | 0 | 1 | 0 | 1 |
30S ribosomal protein S8 | 0 | 1 | 0 | 1 |
30S ribosomal protein S9 | 0 | 1 | 0 | 1 |
50S ribosomal protein L13 | 0 | 1 | 0 | 1 |
50S ribosomal protein L14 | 0 | 1 | 0 | 1 |
50S ribosomal protein L16 | 0 | 1 | 0 | 1 |
50S ribosomal protein L23 | 0 | 1 | 0 | 1 |
30S ribosomal protein S15 | 0 | 1 | 0 | 1 |
50S ribosomal protein L17 | 0 | 1 | 0 | 1 |
50S ribosomal protein L21 | 0 | 1 | 0 | 1 |
50S ribosomal protein L30 | 0 | 1 | 0 | 1 |
50S ribosomal protein L6 | 0 | 1 | 0 | 1 |
30S ribosomal protein S14 | 0 | 1 | 0 | 1 |
30S ribosomal protein S17 | 0 | 1 | 0 | 1 |
30S ribosomal protein S1 | 0 | 1 | 0 | 1 |
50S ribosomal protein L18 | 0 | 1 | 0 | 1 |
Lethal factor | 0 | 1 | 0 | 1 |
50S ribosomal protein L2 | 0 | 1 | 0 | 1 |
50S ribosomal protein L3 | 0 | 1 | 0 | 1 |
50S ribosomal protein L24 | 0 | 1 | 0 | 1 |
50S ribosomal protein L4 | 0 | 1 | 0 | 1 |
50S ribosomal protein L22 | 0 | 1 | 0 | 1 |
50S ribosomal protein L5 | 0 | 1 | 0 | 1 |
30S ribosomal protein S21 | 0 | 1 | 0 | 1 |
50S ribosomal protein L25 | 0 | 1 | 0 | 1 |
50S ribosomal protein L36 2 | 0 | 1 | 0 | 1 |
Protein Rev | 0 | 0 | 1 | 1 |
Aminoglycoside 3'-phosphotransferase | 0 | 0 | 0 | 1 |
Tyrosyl-DNA phosphodiesterase 1 | 0 | 1 | 0 | 1 |
hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
PPM1D protein | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
progesterone receptor | 3 | 0 | 0 | 3 |
nonstructural protein 1 | 2 | 0 | 0 | 2 |
bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
muscleblind-like protein 1 isoform 1 | 2 | 0 | 0 | 2 |
Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
Glucocorticoid receptor | 0 | 4 | 1 | 10 |
Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
Androgen receptor | 0 | 3 | 0 | 3 |
Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
ATPase family AAA domain-containing protein 5 | 3 | 0 | 0 | 3 |
Ataxin-2 | 3 | 0 | 0 | 3 |
Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
TDP1 protein | 3 | 0 | 0 | 3 |
Thioredoxin reductase | 0 | 1 | 0 | 1 |
Histone H2A.x | 1 | 0 | 0 | 1 |
vitamin D3 receptor isoform VDRA | 3 | 0 | 0 | 3 |
thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
Flavodoxin | 0 | 0 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 2 | 0 | 2 |
Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 2 | 0 | 2 |
Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 2 | 0 | 2 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 2 | 0 | 2 |
luciferase | 0 | 0 | 0 | 1 |
RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
Estrogen receptor | 0 | 2 | 0 | 2 |
Progesterone receptor | 0 | 2 | 0 | 3 |
Glucocorticoid receptor | 0 | 1 | 1 | 2 |
Glucocorticoid receptor | 0 | 0 | 1 | 1 |
Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
Androgen receptor | 0 | 2 | 0 | 2 |
Glutamine synthetase | 0 | 0 | 1 | 1 |
Glutamate receptor 2 | 2 | 0 | 0 | 2 |
Histamine H1 receptor | 0 | 0 | 1 | 1 |
Nociceptin receptor | 0 | 0 | 1 | 1 |
Estrogen receptor beta | 0 | 2 | 0 | 2 |
Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
glp-1 receptor, partial | 1 | 0 | 0 | 1 |
pregnane X receptor | 1 | 0 | 0 | 1 |
phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
SMAD family member 2 | 1 | 0 | 0 | 1 |
SMAD family member 3 | 1 | 0 | 0 | 1 |
estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
Histamine H2 receptor | 1 | 0 | 0 | 1 |
Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
Enoyl-[acyl-carrier-protein] reductase [NADH] | 0 | 0 | 0 | 1 |
Protein-arginine deiminase type-4 | 0 | 2 | 0 | 2 |
Sterol 14-alpha-demethylase | 0 | 0 | 1 | 1 |
14-alpha sterol demethylase | 0 | 0 | 1 | 1 |
Cholesterol side-chain cleavage enzyme, mitochondrial | 0 | 0 | 1 | 1 |
Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
14-alpha sterol demethylase | 0 | 0 | 1 | 1 |
Cholesterol 24-hydroxylase | 0 | 2 | 1 | 3 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |