An EC 2.3.2.* (aminoacyltransferase) inhibitor that interferes with the action of protein-glutamine gamma-glutamyltransferase (EC 2.3.2.13).
ChEBI ID: 72716
| Member | Definition | Class |
|---|---|---|
| cystamine | An organic disulfide obtgained by oxidative dimerisation of cysteamine. | cystamine |
| monodansylcadaverine | A sulfonamide obtained by formal condensation of the sulfo group of 5-(dimethylamino)naphthalene-1-sulfonic acid with one of the amino groups of cadaverine. | monodansylcadaverine |
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 688 (48.25) | 18.7374 |
| 1990's | 246 (17.25) | 18.2507 |
| 2000's | 226 (15.85) | 29.6817 |
| 2010's | 227 (15.92) | 24.3611 |
| 2020's | 39 (2.73) | 2.80 |
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 4 (0.24%) | 5.53% |
| Reviews | 34 (2.00%) | 6.00% |
| Case Studies | 7 (0.41%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 1,651 (97.35%) | 84.16% |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| GLS protein | Homo sapiens (human) | Potency | 5.6234 | 1 | 1 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 0.0355 | 1 | 1 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 5.9728 | 1 | 1 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 11.3894 | 4 | 4 |
| Thrombopoietin | Homo sapiens (human) | Potency | 31.6228 | 2 | 2 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 6.3096 | 2 | 2 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 25.1189 | 1 | 1 |