Page last updated: 2024-09-28

Femoral Hernia

A groin hernia occurring inferior to the inguinal ligament and medial to the FEMORAL VEIN and FEMORAL ARTERY. The femoral hernia sac has a small neck but may enlarge considerably when it enters the subcutaneous tissue of the thigh. It is caused by defects in the ABDOMINAL WALL.

Synonyms(2)

Synonym
Hernia, Femoral
Femoral Hernia

Research Excerpts

Research

Studies (47)

TimeframeStudies, This Condition (%)All Conditions %
pre-199024 (51.06)23.3326
1990's11 (23.40)12.5806
2000's5 (10.64)18.1394
2010's6 (12.77)28.8240
2020's1 (2.13)9.53
DrugIndicatedRelationship StrengthStudiesTrials
iodine0low10
urea0low10
diatrizoic acid0low10
bupivacaine0medium41
metrizoate0low10
diazepam0low10
ddt0low10
diethylcarbamazine0low10
lidocaine0medium21
iohexol0low10
mepivacaine0low10
midazolam0low10
papaverine0low10
procaine0low20
propofol0low30
suramin0low10
penicillin g0low10
ethylene0low40
reticulin0low10
streptomycin0low10
iodinated glycerol0low10
methylglucamine metrizoate0low10
tantalum0low10
titanium0medium11
barium sulfate0low10
chlorine0low10
trolamine salicylate0low10
cefonicid0medium11
remifentanil0low10
cephalosporin c0low20
ropivacaine0medium11
dabigatran0low10
cortisone0low10
amoxicillin-potassium clavulanate combination0low10
dextrothyroxine0low10
indocyanine green0low10
sodium ethylxanthate0low10
piperidines0low10
eye0low10

Protein Targets (418)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Potassium channel subfamily K member 30404
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20112
Potassium channel subfamily K member 90101
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
endonuclease IV2002
dopamine D1 receptor1001
thioredoxin reductase5005
pregnane X receptor2002
RAR-related orphan receptor gamma7007
GLS protein5005
TDP1 protein5005
GLI family zinc finger 36006
AR protein6006
aldehyde dehydrogenase 1 family, member A15005
progesterone receptor6006
regulator of G-protein signaling 42002
glucocorticoid receptor [Homo sapiens]3003
retinoic acid nuclear receptor alpha variant 16006
retinoid X nuclear receptor alpha6006
pregnane X nuclear receptor7007
estrogen nuclear receptor alpha6006
peroxisome proliferator-activated receptor delta4004
peroxisome proliferator activated receptor gamma5005
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
euchromatic histone-lysine N-methyltransferase 2100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
v-jun sarcoma virus 17 oncogene homolog (avian)6006
peripheral myelin protein 22 isoform 12002
atrial natriuretic peptide receptor 1 precursor2002
chromobox protein homolog 14004
heat shock protein beta-14004
flap endonuclease 12002
nuclear factor erythroid 2-related factor 2 isoform 15005
geminin6006
survival motor neuron protein isoform d2002
cytochrome P450 3A4 isoform 14004
M-phase phosphoprotein 82002
muscarinic acetylcholine receptor M15005
Gamma-aminobutyric acid receptor subunit pi44210
Bile salt export pump011011
Glucocorticoid receptor0202
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Gamma-aminobutyric acid receptor subunit beta-144210
Gamma-aminobutyric acid receptor subunit delta44210
Gamma-aminobutyric acid receptor subunit gamma-244210
Gamma-aminobutyric acid receptor subunit alpha-544210
Gamma-aminobutyric acid receptor subunit alpha-344210
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit gamma-144210
Gamma-aminobutyric acid receptor subunit alpha-244210
Glycine receptor subunit alpha-30202
Gamma-aminobutyric acid receptor subunit alpha-444210
Gamma-aminobutyric acid receptor subunit gamma-344210
Gamma-aminobutyric acid receptor subunit alpha-644210
Gamma-aminobutyric acid receptor subunit alpha-144210
Gamma-aminobutyric acid receptor subunit beta-344210
Gamma-aminobutyric acid receptor subunit beta-244210
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 431001
GABA theta subunit44210
Multidrug and toxin extrusion protein 10303
Gamma-aminobutyric acid receptor subunit epsilon44210
cytochrome P450 family 3 subfamily A polypeptide 45005
EWS/FLI fusion protein3003
G4004
cytochrome P450 2D62002
Solute carrier family 22 member 20101
Prothrombin0202
Coagulation factor X0101
Plasminogen0101
Coagulation factor XII0101
Tissue-type plasminogen activator0101
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 4004
Vitamin K-dependent protein C0101
Serine protease hepsin0101
Trypsin-10101
Trypsin-20101
Muscarinic acetylcholine receptor M10101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Trypsin-30101
Multidrug and toxin extrusion protein 20101
Inositol hexakisphosphate kinase 14004
cytochrome P450 2C9, partial4004
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, Cruzipain2002
interleukin 81001
hypoxia-inducible factor 1 alpha subunit3003
SMAD family member 21001
SMAD family member 31001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
thyroid stimulating hormone receptor4004
estrogen receptor 2 (ER beta)3003
nuclear receptor subfamily 1, group I, member 35005
estrogen-related nuclear receptor alpha7007
farnesoid X nuclear receptor3003
aryl hydrocarbon receptor2002
thyroid stimulating hormone receptor1001
activating transcription factor 63003
Histone H2A.x4004
Caspase-72002
cellular tumor antigen p53 isoform a1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
thyroid hormone receptor beta isoform a1001
potassium voltage-gated channel subfamily H member 2 isoform d2002
caspase-32002
thyroid hormone receptor beta isoform 24004
mitogen-activated protein kinase 14004
nuclear factor NF-kappa-B p105 subunit isoform 11001
peripheral myelin protein 224004
lethal factor (plasmid)2002
lamin isoform A-delta107007
Voltage-dependent calcium channel gamma-2 subunit3003
Cellular tumor antigen p533003
Androgen receptor0101
Glutamate receptor 23003
Nuclear receptor ROR-gamma1001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, Ferritin light chain2002
Microtubule-associated protein tau3003
nonstructural protein 11001
glucocerebrosidase2002
Bloom syndrome protein isoform 12002
DNA polymerase beta1001
DNA polymerase iota isoform a (long)3003
neuropeptide S receptor isoform A1001
Spike glycoprotein2002
ATP-binding cassette sub-family C member 30505
Multidrug resistance-associated protein 40505
Canalicular multispecific organic anion transporter 10404
Gamma-aminobutyric acid 0101
glp-1 receptor, partial2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Fatty acid-binding protein, liver0101
Alpha-1-acid glycoprotein 10001
Albumin0012
Albumin0011
ATP-dependent translocase ABCB10102
Gamma-aminobutyric acid receptor subunit alpha-10203
Gamma-aminobutyric acid receptor subunit beta-10203
Neuronal acetylcholine receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit alpha-20203
Gamma-aminobutyric acid receptor subunit alpha-30203
Neuronal acetylcholine receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-10336
Translocator protein0214
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20325
5-hydroxytryptamine receptor 1A0213
Gamma-aminobutyric acid receptor subunit alpha-40203
Gamma-aminobutyric acid receptor subunit gamma-20203
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30325
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50235
Gamma-aminobutyric acid receptor subunit alpha-30224
Gamma-aminobutyric acid receptor subunit alpha-20224
Gamma-aminobutyric acid receptor subunit beta-20224
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Neuronal acetylcholine receptor subunit alpha-70101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit pi0101
Sphingosine-1-phosphate lyase 10101
ATPase family AAA domain-containing protein 51001
Ataxin-21001
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0202
Luciferase3003
acetylcholinesterase1001
histone deacetylase 9 isoform 31001
ATAD5 protein, partial1001
Chain A, Beta-lactamase1001
IDH11001
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Potassium voltage-gated channel subfamily H member 20303
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0101
Solute carrier family 22 member 1 0101
ATP-dependent translocase ABCB10101
Cytochrome P450 3A40101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40101
UDP-glucuronosyltransferase 2B10 0101
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0101
15-lipoxygenase, partial1001
phosphopantetheinyl transferase2002
Fumarate hydratase1001
NFKB1 protein, partial1001
PPM1D protein1001
Thrombopoietin1001
polyprotein1001
cytochrome P450 2D6 isoform 12002
hexokinase-4 isoform 11001
polyunsaturated fatty acid lipoxygenase ALOX121001
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor1001
glucokinase regulatory protein1001
atrial natriuretic peptide receptor 2 precursor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
ras-related protein Rab-9A1001
nuclear receptor ROR-gamma isoform 11001
DNA polymerase kappa isoform 12002
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
3',5'-cyclic-AMP phosphodiesterase 0101
Vascular endothelial growth factor receptor 1 0101
Acetylcholinesterase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Cytochrome P450 2C190101
Serine hydroxymethyltransferase, mitochondrial0101
Vascular endothelial growth factor receptor 30101
Vascular endothelial growth factor receptor 20101
Histamine H2 receptor1001
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Disintegrin and metalloproteinase domain-containing protein 171001
Inositol monophosphatase 12002
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0202
CREB-binding protein1001
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A 0202
Phosphodiesterase 0101
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A0102
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
streptokinase A precursor0011
Solute carrier family 22 member 60101
Beta-lactamase0001
Solute carrier family 22 member 80102
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase0001
Kappa-type opioid receptor0001
Solute carrier family 15 member 10101
Beta-lactamase TEM0102
Guanine nucleotide-binding protein G1001
Beta-lactamase0001
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Metallo-beta-lactamase VIM-130001
Beta-lactamase 0001
Beta-lactamase 0001
Efflux transporter 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Beta-lactamase 0001
Class D beta-lactamase0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 22 member 80101
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Beta-lactamase VIM-1 0001
histone acetyltransferase KAT2A isoform 11001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
USP1 protein, partial2002
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
D(1A) dopamine receptor1001
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
5-hydroxytryptamine receptor 40202
Carbonic anhydrase 10101
Carbonic anhydrase 20101
Aldo-keto reductase family 1 member B10202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Prostaglandin G/H synthase 10101
Sodium-dependent noradrenaline transporter 0202
Sodium- and chloride-dependent GABA transporter 10101
5-hydroxytryptamine receptor 2C0202
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
5-hydroxytryptamine receptor 2B0202
Sodium- and chloride-dependent betaine transporter0101
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A80001
Mu-type opioid receptor0101
Sigma non-opioid intracellular receptor 10101
vitamin D3 receptor isoform VDRA2002
Bile salt export pump0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Protein-arginine deiminase type-40202
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
ATP-dependent 6-phosphofructokinase0101
Ectonucleoside triphosphate diphosphohydrolase 20101
Nuclear receptor subfamily 1 group I member 20011
Serine/threonine-protein kinase D30101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Cathepsin B0101
Protein kinase C alpha type0101
Tyrosine-protein phosphatase non-receptor type 10101
D(3) dopamine receptor0101
Protein kinase C eta type0101
Mu-type opioid receptor0011
Delta-type opioid receptor0011
Kappa-type opioid receptor0011
P2Y purinoceptor 20112
Protein kinase C iota type0101
P2X purinoceptor 10011
P2Y purinoceptor 10011
P2X purinoceptor 20112
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2Y purinoceptor 40011
NAD-dependent protein deacetylase HST20101
P2X purinoceptor 30011
DNA-dependent protein kinase catalytic subunit0101
Ectonucleoside triphosphate diphosphohydrolase 10101
DNA primase0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
P2Y purinoceptor 60101
Serine/threonine-protein kinase D10101
Dual specificity protein phosphatase 50101
Ectonucleoside triphosphate diphosphohydrolase 80101
RmtA0101
Reverse transcriptase/RNaseH 0101
Ectonucleoside triphosphate diphosphohydrolase 3 0101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase sirtuin-10101
P2Y purinoceptor 110112
P2X purinoceptor 70011
Protein arginine N-methyltransferase 10101
P2Y purinoceptor 120011
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
ATP-dependent phosphofructokinase1001
Rap guanine nucleotide exchange factor 31001
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]